The circ-AMOTL1/ENO1 Axis Implicated in the Tumorigenesis of OLP-Associated Oral Squamous Cell Carcinoma

References

• Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018;68(6):394–424. doi:10.3322/caac.2149230207593
   PubMed Web of Science ®Google Scholar
• Chow LQM. Head and Neck Cancer. N Engl J Med. 2020;382(1):60–72. doi:10.1056/NEJMra171571531893516
   PubMed Web of Science ®Google Scholar
• González-Moles MÁ, Warnakulasuriya S, González-Ruiz I, et al. Worldwide prevalence of oral lichen planus: A systematic review and meta-analysis. Oral Dis. 2020. doi:10.1111/odi.13323
   Web of Science ®Google Scholar
• González-Moles MÁ, Ruiz-Ávila I, González-Ruiz L, Ayén Á, Gil-Montoya JA, Ramos-García P. Malignant transformation risk of oral lichen planus: A systematic review and comprehensive meta-analysis. Oral Oncol. 2019;96:121–130. doi:10.1016/j.oraloncology.2019.07.01231422203
   PubMed Web of Science ®Google Scholar
• Xing Y, Zhao S, Zhou BP, Mi J. Metabolic reprogramming of the tumour microenvironment. FEBS J. 2015;282(20):3892–3898. doi:10.1111/febs.1340226255648
   PubMed Web of Science ®Google Scholar
• San-Millan I, Brooks GA. Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect. Carcinogenesis. 2017;38(2):119–133. doi:10.1093/carcin/bgw12727993896
   PubMed Web of Science ®Google Scholar
• Asgari Y, Zabihinpour Z, Salehzadeh-Yazdi A, Schreiber F, Masoudi-Nejad A. Alterations in cancer cell metabolism: the Warburg effect and metabolic adaptation. Genomics. 2015;105(5–6):275–281. doi:10.1016/j.ygeno.2015.03.00125773945
   PubMed Web of Science ®Google Scholar
• Dai J, Zhou Q, Chen J, Rexius-Hall ML, Rehman J, Zhou G. Alpha-enolase regulates the malignant phenotype of pulmonary artery smooth muscle cells via the AMPK-Akt pathway. Nat Commun. 2018;9.29339724
   PubMed Web of Science ®Google Scholar
• Yan GR, Xu SH, Tan ZL, et al. Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells. Proteomics. 2011;11(18):3657–3664. doi:10.1002/pmic.20110021521751384
   PubMed Web of Science ®Google Scholar
• Yu S, Li N, Huang Z, et al. A novel lncRNA, TCONS_00006195, represses hepatocellular carcinoma progression by inhibiting enzymatic activity of ENO1. Cell Death Dis. 2018;9(12):1184. doi:10.1038/s41419-018-1231-430518748
   PubMedGoogle Scholar
• Cheng YS, Gould A, Kurago Z, et al. Diagnosis of oral lichen planus: a position paper of the American Academy of Oral and Maxillofacial Pathology. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122(3):332–354. doi:10.1016/j.oooo.2016.05.00427401683
   PubMed Web of Science ®Google Scholar
• Poliseno L, Salmena L, Zhang J, et al. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature. 2010;465(7301):1033–1038. doi:10.1038/nature0914420577206
   PubMed Web of Science ®Google Scholar
• Salmena L, Poliseno L, Tay Y, et al. A ceRNA hypothesis: the Rosetta Stone of a hidden RNA language? Cell. 2011;146(3):353–358. doi:10.1016/j.cell.2011.07.01421802130
   PubMed Web of Science ®Google Scholar
• Yang Q, Xu B, Sun H, et al. A genome-wide association scan of biological processes involved in oral lichen planus and oral squamous cell carcinoma. Medicine. 2017;96(25):e7012. doi:10.1097/MD.000000000000701228640079
   PubMed Web of Science ®Google Scholar
• Yu L, Shen J, Mannoor K, et al. Identification of ENO1 as a potential sputum biomarker for early-stage lung cancer by shotgun proteomics. Clin Lung Cancer. 2014;15(372–378):e1. doi:10.1016/j.cllc.2014.05.00324356090
   PubMedGoogle Scholar
• Okudela K, Mitsui H, Matsumura M, et al. The potential significance of alpha-enolase (ENO1) in lung adenocarcinomas - A utility of the immunohistochemical expression in pathologic diagnosis. Pathol Int. 2017;67(12):602–609. doi:10.1111/pin.1260729090499
   PubMed Web of Science ®Google Scholar
• Racz A, Brass N, Hofer M, Sybrecht GW, Remberger K, Meese EU. Gene amplification at chromosome 1pter-p33 including the genes PAX7 and ENO1 in squamous cell lung carcinoma. Int J Oncol. 2000;17(1):67–73. doi:10.3892/ijo.17.1.6710853020
   PubMed Web of Science ®Google Scholar
• Tsai ST, Chien IH, Shen WH, et al. ENO1, a potential prognostic head and neck cancer marker, promotes transformation partly via chemokine CCL20 induction. Eur J Cancer. 2010;46(9):1712–1723. doi:10.1016/j.ejca.2010.03.01820435467
   PubMed Web of Science ®Google Scholar
• Zhu X, Miao X, Wu Y, et al. ENO1 promotes tumor proliferation and cell adhesion mediated drug resistance (CAM-DR) in Non-Hodgkin’s Lymphomas. Exp Cell Res. 2015;335(2):216–223. doi:10.1016/j.yexcr.2015.05.02026024773
   PubMed Web of Science ®Google Scholar
• Yin H, Wang L, Liu HL. ENO1 Overexpression in Pancreatic Cancer Patients and Its Clinical and Diagnostic Significance. Gastroenterol Res Pract. 2018;2018:3842198.29483925
   PubMed Web of Science ®Google Scholar
• Wang L, Bi R, Yin H, et al. ENO1 silencing impairs hypoxia-induced gemcitabine chemoresistance associated with redox modulation in pancreatic cancer cells. Am J Transl Res. 2019;11(7):4470–4480.31396350
   PubMed Web of Science ®Google Scholar
• Cappello P, Rolla S, Chiarle R, et al. Vaccination with ENO1 DNA prolongs survival of genetically engineered mice with pancreatic cancer. Gastroenterology. 2013;144(5):1098–1106. doi:10.1053/j.gastro.2013.01.02023333712
   PubMed Web of Science ®Google Scholar
• Zhu X, Yu H, Li B, et al. Targeting a LncRNA P5848-ENO1 axis inhibits tumor growth in hepatocellular carcinoma. Biosci Rep. 2018;2:548.
   Google Scholar
• Cancemi P, Buttacavoli M, et al. Expression of Alpha-Enolase (ENO1), Myc Promoter-Binding Protein-1 (MBP-1) and Matrix Metalloproteinases (MMP-2 and MMP-9) Reflect the Nature and Aggressiveness of Breast Tumors. Int J Mol Sci. 2019;20.
   PubMed Web of Science ®Google Scholar
• Qiao H, Wang YF, Yuan WZ, et al. Silencing of ENO1 by shRNA Inhibits the Proliferation of Gastric Cancer Cells. Technol Cancer Res Treat. 2018;17:1533033818784411. doi:10.1177/153303381878441129986635
   PubMed Web of Science ®Google Scholar
• Cappello P, Principe M, Bulfamante S, Novelli F. Alpha-Enolase (ENO1), a potential target in novel immunotherapies. Front Biosci. 2017;22:944–959. doi:10.2741/4526
   PubMed Web of Science ®Google Scholar
• Ejeskar K, Krona C, Caren H, et al. Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death. BMC Cancer. 2005;5(1):161. doi:10.1186/1471-2407-5-16116359544
   PubMedGoogle Scholar
• Zhou X, Zhang Y, Han N, et al. [alpha-Enolase (ENO1) inhibits epithelial-mesenchymal transition in the A549 cell line by suppressing ERK1/2 phosphorylation]. Zhongguo Fei Ai Za Zhi. 2013;16(5):221–226. doi:10.3779/j.issn.1009-3419.2013.05.01. Chiense.23676977
   PubMedGoogle Scholar
• Liu X, Weng Y, Liu P, et al. Identification of PGAM1 as a putative therapeutic target for pancreatic ductal adenocarcinoma metastasis using quantitative proteomics. Onco Targets Ther. 2018;11:3345–3357. doi:10.2147/OTT.S16247029922073
   PubMed Web of Science ®Google Scholar
• Li C, Shu F, Lei B, et al. Expression of PGAM1 in renal clear cell carcinoma and its clinical significance. Int J Clin Exp Pathol. 2015;8(8):9410–9415.26464696
   PubMed Web of Science ®Google Scholar
• Shen Y, Zhao S, Wang S, et al. S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma. EBioMedicine. 2019;40:210–223. doi:10.1016/j.ebiom.2018.12.03830587459
   PubMed Web of Science ®Google Scholar
• Peng XC, Gong FM, Chen Y, et al. Proteomics identification of PGAM1 as a potential therapeutic target for urothelial bladder cancer. J Proteomics. 2016;132:85–92. doi:10.1016/j.jprot.2015.11.02726655504
   PubMed Web of Science ®Google Scholar
• Yang H, He J, Wei W, et al. The c.-360 T>C mutation affects PGAM2 transcription activity and is linked with the water holding capacity of the longissimus lumborum muscle in pigs. Meat Sci. 2016;122:139–144. doi:10.1016/j.meatsci.2016.07.02327538264
   PubMed Web of Science ®Google Scholar
• Geng J, Sun J, Lin Q, et al. Methylation status of NEUROG2 and NID2 improves the diagnosis of stage I NSCLC. Oncol Lett. 2012;3(4):901–906. doi:10.3892/ol.2012.58722741015
   PubMed Web of Science ®Google Scholar
• Knobloch TJ, Ryan NM, Bruschweiler-Li L, et al. Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention. Metabolites. 2019;9.
   PubMed Web of Science ®Google Scholar
• Sarathi A, Palaniappan A. Novel significant stage-specific differentially expressed genes in hepatocellular carcinoma. BMC Cancer. 2019;19(1):663. doi:10.1186/s12885-019-5838-331277598
   PubMedGoogle Scholar
• Zieker D, Konigsrainer I, Traub F, et al. PGK1 a potential marker for peritoneal dissemination in gastric cancer. Cell Physiol Biochem. 2008;21(5–6):429–436. doi:10.1159/00012963518453750
   PubMedGoogle Scholar
• Zhou JW, Tang JJ, Sun W, et al. PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma. Mol Med. 2019;25(1):11. doi:10.1186/s10020-019-0079-030925862
   PubMedGoogle Scholar
• Yu T, Zhao Y, Hu Z, et al. MetaLnc9 Facilitates Lung Cancer Metastasis via a PGK1-Activated AKT/mTOR Pathway. Cancer Res. 2017;77(21):5782–5794. doi:10.1158/0008-5472.CAN-17-067128923857
   PubMed Web of Science ®Google Scholar
• Xu D, Aka JA, Wang R, Lin SX. 17beta-hydroxysteroid dehydrogenase type 5 is negatively correlated to apoptosis inhibitor GRP78 and tumor-secreted protein PGK1, and modulates breast cancer cell viability and proliferation. J Steroid Biochem Mol Biol. 2017;171:270–280. doi:10.1016/j.jsbmb.2017.04.00928457968
   PubMed Web of Science ®Google Scholar
• Xie H, Tong G, Zhang Y, Liang S, Tang K, Yang Q. PGK1 Drives Hepatocellular Carcinoma Metastasis by Enhancing Metabolic Process. Int J Mol Sci. 2017;18.
   PubMed Web of Science ®Google Scholar
• Tarnopolsky MA. Myopathies Related to Glycogen Metabolism Disorders. Neurotherapeutics. 2018;15(4):915–927. doi:10.1007/s13311-018-00684-230397902
   PubMed Web of Science ®Google Scholar
• Wu G, Guo Z, Chatterjee A, et al. Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. Cancer Res. 2006;66(20):9829–9836. doi:10.1158/0008-5472.CAN-06-050617047043
   PubMed Web of Science ®Google Scholar
• Lyu Z, Chen Y, Guo X, Zhou F, Yan Z, Xing J. Genetic variants in glucose-6-phosphate isomerase gene as prognosis predictors in hepatocellular carcinoma. Clin Res Hepatol Gastroenterol. 2016;40(6):698–704. doi:10.1016/j.clinre.2016.05.00127288297
   PubMed Web of Science ®Google Scholar
• Ma YT, Xing XF, Dong B, Cheng XJ, Guo T, Du H. Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer. Cancer Manag Res. 2018;10:4969–4980. doi:10.2147/CMAR.S17744130464597
   PubMed Web of Science ®Google Scholar
• Puzone R, Savarino G, Salvi S, et al. Glyceraldehyde-3-phosphate dehydrogenase gene over expression correlates with poor prognosis in non small cell lung cancer patients. Mol Cancer. 2013;12(1):97. doi:10.1186/1476-4598-12-9723988223
   PubMedGoogle Scholar
• Husi H, Fernandes M, Skipworth RJ, Miller J, Cronshaw AD. Identification of diagnostic upper gastrointestinal cancer tissue type-specific urinary biomarkers. Biomed Rep. 2019;10(3):165–174. doi:10.3892/br.2019.119030906545
   PubMed Web of Science ®Google Scholar
• Kumamoto K, Nakachi Y, Mizuno Y, et al. Expressions of 10 genes as candidate predictors of recurrence in stage III colon cancer patients receiving adjuvant oxaliplatin-based chemotherapy. Oncol Lett. 2019;18(2):1388–1394. doi:10.3892/ol.2019.1043731423202
   PubMed Web of Science ®Google Scholar
• Yang Q, Du WW, Wu N, et al. A circular RNA promotes tumorigenesis by inducing c-myc nuclear translocation. Cell Death Differ. 2017;24(9):1609–1620. doi:10.1038/cdd.2017.8628622299
   PubMed Web of Science ®Google Scholar
• Yang Z, Qu CB, Zhang Y, et al. Dysregulation of p53-RBM25-mediated circAMOTL1L biogenesis contributes to prostate cancer progression through the circAMOTL1L-miR-193a-5p-Pcdha pathway. Oncogene. 2019;38(14):2516–2532. doi:10.1038/s41388-018-0602-830531834
   PubMed Web of Science ®Google Scholar
• Wan HY, Li QQ, Zhang Y, Tian W, Li YN, Liu M. MiR-124 represses vasculogenic mimicry and cell motility by targeting amotL1 in cervical cancer cells. Cancer Lett. 2014;355(1):148–158. doi:10.1016/j.canlet.2014.09.00525218344
   PubMed Web of Science ®Google Scholar
• Couderc C, Boin A, Fuhrmann L, et al. AMOTL1 Promotes Breast Cancer Progression and Is Antagonized by Merlin. Neoplasia. 2016;18(1):10–24. doi:10.1016/j.neo.2015.11.01026806348
   PubMed Web of Science ®Google Scholar
• Zheng Y, Zhang Y, Barutello G, Chiu K, Arigoni M, Giampietro C. Angiomotin like-1 is a novel component of the N-cadherin complex affecting endothelial/pericyte interaction in normal and tumor angiogenesis. Sci Rep. 2016;6(1):30622. doi:10.1038/srep3062227464479
   PubMedGoogle Scholar
• Lv KT, Liu Z, Feng J, Zhao W, Hao T. MiR-22-3p Regulates Cell Proliferation and Inhibits Cell Apoptosis through Targeting the eIF4EBP3 Gene in Human Cervical Squamous Carcinoma Cells. Int J Med Sci. 2018;15:142–152. doi:10.7150/ijms.2164529333098
   PubMed Web of Science ®Google Scholar
• Wang M, Chen B, Ru Z, Cong L. CircRNA circ-ITCH suppresses papillary thyroid cancer progression through miR-22-3p/CBL/beta-catenin pathway. Biochem Biophys Res Commun. 2018;504(1):283–288. doi:10.1016/j.bbrc.2018.08.17530190130
   PubMed Web of Science ®Google Scholar
• Hussein NA, Kholy ZA, Anwar MM, Ahmad MA, Ahmad SM. Plasma miR-22-3p, miR-642b-3p and miR-885-5p as diagnostic biomarkers for pancreatic cancer. J Cancer Res Clin Oncol. 2017;143(1):83–93. doi:10.1007/s00432-016-2248-727631726
   PubMed Web of Science ®Google Scholar
• Sha QK, Chen L, Xi JZ, Song H. Long non-coding RNA LINC00858 promotes cells proliferation, migration and invasion by acting as a ceRNA of miR-22-3p in colorectal cancer. Artif Cells Nanomed Biotechnol. 2019;47(1):1057–1066. doi:10.1080/21691401.2018.154414330931636
   PubMed Web of Science ®Google Scholar
• Chen J, Wu FX, Luo HL, Liu JJ, Luo T, Bai T. Berberine upregulates miR-22-3p to suppress hepatocellular carcinoma cell proliferation by targeting Sp1. Am J Transl Res. 2016;8(11):4932–4941.27904693
   PubMed Web of Science ®Google Scholar
• Zhang Y, Huang S, Guo Y, Li L. MiR-1294 confers cisplatin resistance in ovarian Cancer cells by targeting IGF1R. Biomed Pharmacother. 2018;106:1357–1363. doi:10.1016/j.biopha.2018.07.05930119207
   PubMed Web of Science ®Google Scholar
• Pan W, Pang LJ, Cai HL, Wu Y, Zhang W, Fang J-C. MiR-1294 acts as a tumor suppressor in clear cell renal cell carcinoma through targeting HOXA6. Eur Rev Med Pharmacol Sci. 2019;23(9):3719–3725. doi:10.26355/eurrev_201905_1779731114997
   PubMed Web of Science ®Google Scholar
• Xu Y, Yao Y, Gao P, Cui Y. Upregulated circular RNA circ_0030235 predicts unfavorable prognosis in pancreatic ductal adenocarcinoma and facilitates cell progression by sponging miR-1253 and miR-1294. Biochem Biophys Res Commun. 2019;509(1):138–142. doi:10.1016/j.bbrc.2018.12.08830591218
   PubMed Web of Science ®Google Scholar
• Zhang Z, Lin W, Gao L, et al. Hsa_circ_0004370 promotes esophageal cancer progression through miR-1294/LASP1 pathway. Biosci Rep. 2019;39.
   Web of Science ®Google Scholar
• Yang Q, Guo B, Sun H, et al. Identification of the key genes implicated in the transformation of OLP to OSCC using RNA-sequencing. Oncol Rep. 2017;37(4):2355–2365. doi:10.3892/or.2017.548728259920
   PubMed Web of Science ®Google Scholar