Advanced search
Publication Cover
Cancer Management and Research Volume 12, 2020 - Issue
Submit an article Journal homepage
74
Views
12
CrossRef citations to date
0
Altmetric
Original Research

miR-100-5p Inhibits Malignant Behavior of Chordoma Cells by Targeting IGF1R

Hongliang Zhang1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Kang Yang3 Department of Orthopedics, Yangzhou University Affiliated Hospital, Yangzhou, People’s Republic of China
,
Tingting Ren1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Yi Huang1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Xin Liang1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Yiyang Yu1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Wei Wang1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Jianfang Niu1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Jingbing Lou1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
,
Xiaodong Tang1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Wei Guo1 Musculoskeletal Tumor Center, Peking University People’s Hospital, Beijing, People’s Republic of China;2 Beijing Key Laboratory of Musculoskeletal Tumor, Beijing, People’s Republic of China
 show all
Pages 4129-4137 | Published online: 02 Jun 2020

References

  • Yamaguchi T, Yamato M, Saotome K. First histologically confirmed case of a classic chordoma arising in a precursor benign notochordal lesion: differential diagnosis of benign and malignant notochordal lesions. Skeletal Radiol. 2002;31(7):413–418. doi:10.1007/s00256-002-0514-z12107574
  • Smoll NR, Gautschi OP, Radovanovic I, Schaller K, Weber DC. Incidence and relative survival of chordomas: the standardized mortality ratio and the impact of chordomas on a population. Cancer. 2013;119(11):2029–2037. doi:10.1002/cncr.2803223504991
  • Yu SL, Chen HY, Chang GC, et al. MicroRNA signature predicts survival and relapse in lung cancer. Cancer Cell. 2008;13(1):48–57. doi:10.1016/j.ccr.2007.12.00818167339
  • Zhang H, Yang K, Ren T, Huang Y, Tang X, Guo W. miR-16-5p inhibits chordoma cell proliferation, invasion and metastasis by targeting Smad3. Cell Death Dis. 2018;9(6):680. doi:10.1038/s41419-018-0738-z29880900
  • Chen P, Lin C, Quan J, et al. Oncogenic miR-100-5p is associated with cellular viability, migration, and apoptosis in renal cell carcinoma. Mol Med Rep. 2017;16(4):5023–5030. doi:10.3892/mmr.2017.713928765937
  • Wang J, Yu M, Guan S, Zhang G, Wang J, Cheng Y. Prognostic significance of microRNA-100 in solid tumors: an updated meta-analysis. Onco Targets Ther. 2017;10:493–502. doi:10.2147/OTT.S12277428176958
  • Faustino-Rocha A, Oliveira PA, Pinho-Oliveira J, et al. Estimation of rat mammary tumor volume using caliper and ultrasonography measurements. Lab Anim. 2013;42(6):217–224. doi:10.1038/laban.254
  • Osaka E, Kelly AD, Spentzos D, et al. MicroRNA-155 expression is independently predictive of outcome in chordoma. Oncotarget. 2015;6(11):9125–9139. doi:10.18632/oncotarget.327325823817
  • Malgulwar PB, Pathak P, Singh M, et al. Downregulation of SMARCB1/INI1 expression in pediatric chordomas correlates with upregulation of miR-671-5p and miR-193a-5p expressions. Brain Tumor Pathol. 2017;34(4):155–159. doi:10.1007/s10014-017-0295-728825187
  • Zou MX, Huang W, Wang XB, et al. Reduced expression of miRNA-1237-3p associated with poor survival of spinal chordoma patients. Eur Spine J. 2015;24(8):1738–1746. doi:10.1007/s00586-015-3927-925850393
  • Zhang Y, Schiff D, Park D, Abounader R. MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET. PLoS One. 2014;9(3):e91546. doi:10.1371/journal.pone.009154624621885
  • Henson BJ, Bhattacharjee S, O’Dee DM, Feingold E, Gollin SM. Decreased expression of miR-125b and miR-100 in oral cancer cells contributes to malignancy. Genes Chromosomes Cancer. 2009;48(7):569–582. doi:10.1002/gcc.2066619396866
  • Rucker FG, Russ AC, Cocciardi S, et al. Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance. Leukemia. 2013;27(2):353–361. doi:10.1038/leu.2012.20822810507
  • Sun X, Liu X, Wang Y, Yang S, Chen Y, Yuan T. miR-100 inhibits the migration and invasion of nasopharyngeal carcinoma by targeting IGF1R. Oncol Lett. 2018;15(6):8333–8338. doi:10.3892/ol.2018.842029805566
  • Torres A, Torres K, Pesci A, et al. Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma. BMC Cancer. 2012;12:369. doi:10.1186/1471-2407-12-36922920721
  • Wang YH, Wang ZX, Qiu Y, et al. Lentivirus-mediated RNAi knockdown of insulin-like growth factor-1 receptor inhibits growth, reduces invasion, and enhances radiosensitivity in human osteosarcoma cells. Mol Cell Biochem. 2009;327(1–2):257–266. doi:10.1007/s11010-009-0064-y19229591
  • Codony-Servat J, Cuatrecasas M, Asensio E, et al. Nuclear IGF-1R predicts chemotherapy and targeted therapy resistance in metastatic colorectal cancer. Br J Cancer. 2017;117(12):1777–1786. doi:10.1038/bjc.2017.27929123263
  • Pian L, Wen X, Kang L, et al. Targeting the IGF1R pathway in breast cancer using antisense lncRNA-mediated promoter cis competition. Mol Ther Nucleic Acids. 2018;12:105–117. doi:10.1016/j.omtn.2018.04.01330195750
  • Ahearn TU, Peisch S, Pettersson A, et al. Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease. Carcinogenesis. 2018;39(12):1431–1437. doi:10.1093/carcin/bgy11230165429
  • Jentzsch T, Robl B, Husmann M, Bode-Lesniewska B, Fuchs B. Worse prognosis of osteosarcoma patients expressing IGF-1 on a tissue microarray. Anticancer Res. 2014;34(8):3881–3889.25075009

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.