Predicting Prognosis and Adverse Events by Hematologic Markers in Patients with Locally Advanced Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Chemoradiotherapy

References

• Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65:87–108. doi:10.3322/caac.2126225651787
   PubMed Web of Science ®Google Scholar
• Lin Y, Totsuka Y, He Y, et al. Epidemiology of esophageal cancer in Japan and China. J Epidemiol. 2013;23:233–242. doi:10.2188/jea.JE2012016223629646
   PubMed Web of Science ®Google Scholar
• Rustgi AK, El-Serag HB. Esophageal carcinoma. N Engl J Med. 2014;371:2499–2509. doi:10.1056/NEJMra131453025539106
   PubMed Web of Science ®Google Scholar
• Lagergren J, Smyth E, Cunningham D, et al. Oesophageal cancer. Lancet. 2017;390:2383–2396. doi:10.1016/S0140-6736(17)31462-928648400
   PubMed Web of Science ®Google Scholar
• Yang H, Liu H, Chen Y, et al. Neoadjuvant chemoradiotherapy followed by surgery versus surgery alone for locally advanced squamous cell carcinoma of the esophagus (NEOCRTEC5010): a Phase III multicenter, randomized, open-label clinical trial. J Clin Oncol. 2018;36:2796–2803. doi:10.1200/JCO.2018.79.148330089078
   PubMed Web of Science ®Google Scholar
• Coussens LM, Werb Z. Inflammation and cancer. Nature. 2002;420(6917):860–867. doi:10.1038/nature0132212490959
   PubMed Web of Science ®Google Scholar
• Grivennikov SI, Greten FR, Karin M. Immunity, inflammation and cancer. Cell. 2010;140:883–899. doi:10.1016/j.cell.2010.01.02520303878
   PubMed Web of Science ®Google Scholar
• Guthrie GJ, Charles KA, Roxburgh CS, et al. The systemic inflammation-based neutrophil-lymphocyte ratio: experience in patients with cancer. Crit Rev Oncol Hematol. 2013;88:218–230. doi:10.1016/j.critrevonc.2013.03.01023602134
   PubMed Web of Science ®Google Scholar
• Templeton AJ, Ace O, McNamara MG, et al. Prognostic role of platelet to lymphocyte ratio in solid tumors: a systematic review and meta-analysis. Cancer Epidemiol Biomarkers Prev. 2014;23:1204–1212. doi:10.1158/1055-9965.EPI-14-014624793958
   PubMed Web of Science ®Google Scholar
• Proctor MJ, McMillan DC, Morrison DS, et al. A derived neutrophil to lymphocyte ratio predicts survival in patients with cancer. Br J Cancer. 2012;107:695–699. doi:10.1038/bjc.2012.29222828611
   PubMed Web of Science ®Google Scholar
• Miyatani K, Saito H, Kono Y, et al. Combined analysis of the pre- and postoperative neutrophil-lymphocyte ratio predicts the outcomes of patients with gastric cancer. Surg Today. 2018;48(3):300–307. doi:10.1007/s00595-017-1587-628916967
   PubMed Web of Science ®Google Scholar
• Muhaxheri G, Vucicevic Boras V, Fucic A, et al. Multivariate analysis of preoperative and postoperative neutrophil-to-lymphocyte ratio as an indicator of head and neck squamous cell carcinoma outcome. Int J Oral Maxillofac Surg. 2018;47(8):965–970. doi:10.1016/j.ijom.2018.02.01129559186
   PubMed Web of Science ®Google Scholar
• Xie X, Luo KJ, Hu Y, et al. Prognostic value of preoperative platelet-lymphocyte and neutrophil-lymphocyte ratio in patients undergoing surgery for esophageal squamous cell cancer. Dis Esophagus. 2016;29:79–85. doi:10.1111/dote.1229625410116
   PubMed Web of Science ®Google Scholar
• Liu X, Li M, Zhao F, et al. The lymphocyte-monocyte ratio predicts tumor response and survival in patients with locally advanced esophageal cancer who received definitive chemoradiotherapy. Onco Targets Ther. 2017;10:871–877. doi:10.2147/OTT.S12491528243122
   PubMed Web of Science ®Google Scholar
• Barbetta A, Nobel TB, Sihag S, et al. Neutrophil to lymphocyte ratio as predictor of treatment response in esophageal squamous cell cancer. Ann Thorac Surg. 2018;106:864–871. doi:10.1016/j.athoracsur.2018.04.00729738752
   PubMed Web of Science ®Google Scholar
• Sun Y, Zhang L. The clinical use of pretreatment NLR, PLR, and LMR in patients with esophageal squamous cell carcinoma: evidence from a meta-analysis. Cancer Manag Res. 2018;10:6167–6179. doi:10.2147/CMAR.S17103530538564
   PubMed Web of Science ®Google Scholar
• Gao Y, Guo W, Cai S, et al. Systemic immune-inflammation index (SII) is useful to predict survival outcomes in patients with surgically resected esophageal squamous cell carcinoma. J Cancer. 2019;10:3188–3196. doi:10.7150/jca.3028131289589
   PubMed Web of Science ®Google Scholar
• Zhang H, Shang X, Ren P, et al. The predictive value of a preoperative systemic immune-inflammation index and prognostic nutritional index in patients with esophageal squamous cell carcinoma. J Cell Physiol. 2019;234:1794–1802.30070689
   PubMed Web of Science ®Google Scholar
• Davalos D, Akassoglou K. Fibrinogen as a key regulator of inflammation in disease. Semin Immunopathol. 2012;34:43–62. doi:10.1007/s00281-011-0290-822037947
   PubMed Web of Science ®Google Scholar
• Schafer AI. The hypercoagulable states. Ann Intern Med. 1985;102(6):814–828. doi:10.7326/0003-4819-102-6-8143158262
   PubMed Web of Science ®Google Scholar
• Ding J, Karp JE, Emadi A. Elevated lactate dehydrogenase (LDH) can be a marker of immune suppression in cancer: interplay between hematologic and solid neoplastic clones and their microenvironments. Cancer Biomark. 2017;19(4):353–363. doi:10.3233/CBM-16033628582845
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xiao G. Prognostic significance of the ratio of fibrinogen and albumin in human malignancies: a meta-analysis. Cancer Manag Res. 2019;11:3381–3393. doi:10.2147/CMAR.S19841931114374
   PubMed Web of Science ®Google Scholar
• Sun F, Tan YA, Gao QF, et al. Circulating fibrinogen to pre-albumin ratio is a promising biomarker for diagnosis of colorectal cancer. J Clin Lab Anal. 2019;33:e22635. doi:10.1002/jcla.2263530047185
   PubMed Web of Science ®Google Scholar
• Gupta D, Lis CG. Pretreatment serum albumin as a predictor of cancer survival: a systematic review of the epidemiological literature. Nutr J. 2010;9:69. doi:10.1186/1475-2891-9-6921176210
   PubMed Web of Science ®Google Scholar
• Song S, Li C, Li S, et al. Derived neutrophil to lymphocyte ratio and monocyte to lymphocyte ratio may be better biomarkers for predicting overall survival of patients with advanced gastric cancer. Onco Targets Ther. 2017;10:3145–3154. doi:10.2147/OTT.S13803928706446
   PubMed Web of Science ®Google Scholar
• Jin Y, Ye X, Shao L, et al. Serum lactic dehydrogenase strongly predicts survival in metastatic nasopharyngeal carcinoma treated with palliative chemotherapy. Eur J Cancer. 2013;49:1619–1626.23266049
   PubMed Web of Science ®Google Scholar
• Halabi S, Small EJ, Kantoff PW, et al. Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer. J Clin Oncol. 2003;21:1232–1237. doi:10.1200/JCO.2003.06.10012663709
   PubMed Web of Science ®Google Scholar
• Tan Z, Zhang M, Han Q, et al. A novel tool of cancer prognosis in esophageal squamous cell carcinoma: the Fibrinogen/Albumin Ratio. J Cancer. 2017;8:1025–1029. doi:10.7150/jca.1649128529615
   PubMed Web of Science ®Google Scholar
• Matsuda S, Takeuchi H, Kawakubo H, et al. Prognostic impact of change in the fibrinogen and albumin score during preoperative treatment in esophageal cancer patients. World J Surg. 2017;41:2788–2795. doi:10.1007/s00268-017-4074-828608015
   PubMed Web of Science ®Google Scholar
• asWei XL, Zhang DS, He MM, et al. The predictive value of alkaline phosphatase and lactate dehydrogenase for overall survival in patients with esophageal squamous cell carcinoma. Tumour Biol. 2016;37:1879–1887.26323257
   PubMedGoogle Scholar
• Rice TW, Blackstone EH, Rusch VW. 7th edition of the AJCC cancer staging manual: esophagus and esophagogastric junction. Ann Surg Oncol. 2010;17:1721–1724.20369299
   PubMed Web of Science ®Google Scholar
• Eisenhauer EA, Therasse P, Bogaerts J. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer. 2009;45:228–247. doi:10.1016/j.ejca.2008.10.02619097774
   PubMed Web of Science ®Google Scholar
• Wijsman R, Dankers FJWM, Troost EGC, et al. Inclusion of incidental radiation dose to the cardiac atria and ventricles does not improve the prediction of radiation pneumonitis in advanced-stage non-small cell lung cancer patients treated with intensity modulated radiation therapy. Int J Radiat Oncol Biol Phys. 2017;99:434–441. doi:10.1016/j.ijrobp.2017.04.01128871994
   PubMed Web of Science ®Google Scholar
• Kim DY, Kim IS, Park SG. Prognostic value of posttreatment neutrophil-lymphocyte ratio in head and neck squamous cell carcinoma treated by chemoradiotherapy. Auris Nasus Larynx. 2017;44:199–204. doi:10.1016/j.anl.2016.05.01327269133
   PubMed Web of Science ®Google Scholar
• Lin YH, Lin YS. Platelet-lymphocyte and neutrophil-lymphocyte ratios: predictive factors of response and toxicity for docetaxel-combined induction chemotherapy in advanced head and neck cancers. J Chin Med Assoc. 2019;82:849–855. doi:10.1097/JCMA.000000000000017831453862
   PubMed Web of Science ®Google Scholar
• Bekes EM, Schweighofer B, Kupriyanova TA, et al. Tumorrecruited neutrophils and neutrophil TIMP-free MMP-9 regulate coordinately the levels of tumor angiogenesis and efficiency of malignant cell intravasation. Am J Pathol. 2011;179:1455–1470. doi:10.1016/j.ajpath.2011.05.03121741942
   PubMed Web of Science ®Google Scholar
• Liang W, Ferrara N. The complex role of neutrophils in tumor angiogenesis and metastasis. Cancer Immunol Res. 2016;4:83–91. doi:10.1158/2326-6066.CIR-15-031326839309
   PubMed Web of Science ®Google Scholar
• Moses K, Brandau S. Human neutrophils: there role in cancer and relation to myeloid-derived suppressor cells. Semin Immunol. 2016;28:187–196. doi:10.1016/j.smim.2016.03.01827067179
   PubMed Web of Science ®Google Scholar
• Rabinowich H, Cohen R, Bruderman I, et al. Functional analysis of mononuclear cells infiltrating into tumors: lysis of autologous human tumor cells by cultured infiltrating lymphocytes. Cancer Res. 1987;47(1):173–177.3491673
   PubMed Web of Science ®Google Scholar
• Lanitis E, Dangaj D, Irving M, et al. Mechanisms regulating T-cell infiltration and activity in solid tumors. Ann Oncol. 2017;28:xii18–xii32. doi:10.1093/annonc/mdx23829045511
   PubMed Web of Science ®Google Scholar
• Jain S, Harris J, Ware J. Platelets: linking hemostasis and cancer. Arterioscler Thromb Vasc Biol. 2010;30:2362–2367. doi:10.1161/ATVBAHA.110.20751421071699
   PubMed Web of Science ®Google Scholar
• Honn KV, Tang DG, Crissman JD. Platelets and cancer metastasis: a causal relationship? Cancer Metastasis Rev. 1992;11:325–351. doi:10.1007/BF013071861423821
   PubMed Web of Science ®Google Scholar
• Gao QF, Qiu JC, Huang XH, et al. The predictive and prognostic role of a novel ADS score in esophageal squamous cell carcinoma patients undergoing esophagectomy. Cancer Cell Int. 2018;18:153. doi:10.1186/s12935-018-0648-230305803
   PubMed Web of Science ®Google Scholar
• Jain R, Yee JL, Shaikh T, et al. Treatment-related toxicity and outcomes in older versus younger patients with esophageal cancer treated with neoadjuvant chemoradiation. J Geriatr Oncol. 2019;S1879–4068(19):30088–30098.
   Google Scholar
• Yu X, Wen Y, Lin Y, et al. The value of preoperative glasgow prognostic score and the C-reactive protein to albumin ratio as prognostic factors for long-term survival in pathological T1N0 esophageal squamous cell carcinoma. J Cancer. 2018;9:807–815. doi:10.7150/jca.2275529581759
   PubMed Web of Science ®Google Scholar
• Hudson J, Semenkovich T, Puri V. Oncologic quality indicators in thoracic surgery. Thorac Surg Clin. 2017;27(3):227–244. doi:10.1016/j.thorsurg.2017.04.00128647069
   PubMed Web of Science ®Google Scholar