References
- KotlaVGoelSNischalSMechanism of action of lenalidomide in hematological malignanciesJ Hematol Oncol200923619674465
- ValletSWitzens-HarigMJaegerDPodarKUpdate on immunomodulatory drugs (IMiDs) in hematologic and solid malignanciesExpert Opin Pharmacother201213447349422324734
- DaviesFBazRLenalidomide mode of action: linking bench and clinical findingsBlood Rev201024 Suppl 1S13S1921126632
- RichardsonPGSchlossmanRLWellerEImmunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myelomaBlood200210093063306712384400
- HideshimaTChauhanDShimaYThalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapyBlood20009692943295011049970
- MitsiadesNMitsiadesCSPoulakiVApoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implicationsBlood200299124525453012036884
- VerhelleDCorralLGWongKLenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cellsCancer Res200767274675517234786
- JakubikovaJAdamiaSKost-AlimovaMLenalidomide targets clonogenic side population in multiple myeloma: pathophysiologic and clinical implicationsBlood2011117174409441921321360
- ItoTAndoHSuzukiTIdentification of a primary target of thalidomide teratogenicityScience201032759711345135020223979
- ZhuYXBraggioEShiCXCereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomideBlood2011118184771477921860026
- GeitzHHandtSZwingenbergerKThalidomide selectively modulates the density of cell surface molecules involved in the adhesion cascadeImmunopharmacology1996312–32132218861747
- HideshimaTChauhanDSchlossmanRRichardsonPAndersonKCThe role of tumor necrosis factor alpha in the pathophysiology of human multiple myeloma: therapeutic applicationsOncogene200120334519452711494147
- CorralLGHaslettPAMullerGWDifferential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alphaJ Immunol1999163138038610384139
- GuptaDTreonSPShimaYAdherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applicationsLeukemia200115121950196111753617
- De LuisiAFerrucciAColucciaAMLenalidomide restrains motility and overangiogenic potential of bone marrow endothelial cells in patients with active multiple myelomaClin Cancer Res20111771935194621307145
- BreitkreutzIRaabMSValletSLenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myelomaLeukemia200822101925193218596740
- DaviesFERajeNHideshimaTThalidomide and immunomodulatory derivatives augment natural killer cell cytotoxicity in multiple myelomaBlood200198121021611418482
- ChangDHLiuNKlimekVEnhancement of ligand-dependent activation of human natural killer T cells by lenalidomide: therapeutic implicationsBlood2006108261862116569772
- GalustianCMeyerBLabartheMCThe anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cellsCancer Immunol Immunother20095871033104519009291
- MullerGWChenRHuangSYAmino-substituted thalidomide analogs: potent inhibitors of TNF-alpha productionBioorg Med Chem Lett19999111625163010386948
- LeBlancRHideshimaTCatleyLPImmunomodulatory drug costimulates T cells via the B7-CD28 pathwayBlood200410351787179014512311
- GorgunGCalabreseESoydanEImmunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myelomaBlood2010116173227323720651070
- RichardsonPGBloodEMitsiadesCSA randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myelomaBlood2006108103458346416840727
- RichardsonPJagannathSHusseinMSafety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myelomaBlood2009114477277819471019
- DimopoulosMSpencerAAttalMfor Multiple Myeloma (010) Study InvestigatorsLenalidomide plus dexamethasone for relapsed or refractory multiple myelomaN Engl J Med2007357212123213218032762
- WeberDMChenCNiesvizkyRfor Multiple Myeloma (009) Study InvestigatorsLenalidomide plus dexamethasone for relapsed multiple myeloma in North AmericaN Engl J Med2007357212133214218032763
- DimopoulosMAChenCSpencerALong-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myelomaLeukemia200923112147215219626046
- HarousseauJLDimopoulosMAWangMBetter quality of response to lenalidomide plus dexamethasone is associated with improved clinical outcomes in patients with relapsed or refractory multiple myelomaHaematologica201095101738174420460639
- San-MiguelJFDimopoulosMAStadtmauerEAEffects of lenalidomide and dexamethasone treatment duration on survival in patients with relapsed or refractory multiple myeloma treated with lenalidomide and dexamethasoneClin Lymphoma Myeloma Leuk2011111384321273172
- San MiguelJDimopoulosMBravoMLWeberDLonger duration of treatment and maintenance of best response with lenalidomide + dexamethasone increases overall survival (OS) in patients with relapsed/refractory multiple myeloma [abstract]Haematologica200994Suppl 2382
- San MiguelJFDimopoulosMWeberDDexamethasone dose adjustments seem to result in better efficacy and improved tolerability in patients with relapsed/refractory multiple myeloma who are treated with lenalidomide/dexamethasone (MM009/010 sub-analysis) [abstract]Blood (ASH Annual Meeting Abstracts)2007110112712
- RajkumarSVJacobusSCallanderNSfor Eastern Cooperative Oncology GroupLenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trialLancet Oncol2010111293719853510
- DimopoulosMAHusseinMSwernASWeberDImpact of lenalidomide dose on progression-free survival in patients with relapsed or refractory multiple myelomaLeukemia201125101620162621747400
- StadtmauerEAWeberDMNiesvizkyRLenalidomide in combination with dexamethasone at first relapse in comparison with its use as later salvage therapy in relapsed or refractory multiple myelomaEur J Haematol200982642643219302559
- WangMDimopoulosMAChenCLenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposureBlood2008112124445445118799726
- Avet-LoiseauHSoulierJFermandJPfor IFM MAG groupsImpact of high-risk cytogenetics and prior therapy on outcomes in patients with advanced relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasoneLeukemia201024362362820072152
- GuglielmelliTBringhenSRrodheSPrevious thalidomide therapy may not affect lenalidomide response and outcome in relapse or refractory multiple myeloma patientsEur J Cancer201147681481821334196
- KneppersELokhorstHMEeltinkCMAnalysis of efficacy and prognostic factors of lenalidomide treatment as part of a Dutch compassionate use programClin Lymphoma Myeloma Leuk201010213814320371448
- MateosMVRichardsonPGSchlagRBortezomib plus melphalan and prednisone compared with melphalan and prednisone in previously untreated multiple myeloma: updated follow-up and impact of subsequent therapy in the phase III VISTA trialJ Clin Oncol201028132259226620368561
- ReeceDSongKWFuTInfluence of cytogenetics in patients with relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasone: adverse effect of deletion 17p13Blood2009114352252519332768
- KleinUNebenKHielscherTHeissCHoADGoldschmidtHLenalidomide in combination with dexamethasone: effective regimen in patients with relapsed or refractory multiple myeloma complicated by renal impairmentAnn Hematol201190442943920857112
- ChangHJiangAQiCTrieuYChenCReeceDImpact of genomic aberrations including chromosome 1 abnormalities on the outcome of patients with relapsed or refractory multiple myeloma treated with lenalidomide and dexamethasoneLeuk Lymphoma201051112084209120929319
- KnopSGereckeCLiebischPLenalidomide, adriamycin, and dexamethasone (RAD) in patients with relapsed and refractory multiple myeloma: a report from the German Myeloma Study Group DSMM (Deutsche Studiengruppe Multiples Myelom)Blood2009113184137414319182205
- BazRWalkerEKaramMALenalidomide and pegylated liposomal doxorubicin-based chemotherapy for relapsed or refractory multiple myeloma: safety and efficacyAnn Oncol200617121766177116980599
- LentzschSO’SullivanAKennedyRCombination of bendamustine, lenalidomide, and dexamethasone (BLD) in patients with refractory or relapsed multiple myeloma is safe and highly effective: results of phase I/II open-label, dose escalation study [abstract]Blood (ASH Annual Meeting Abstracts)201111821304
- PonischWHeynSWagnerICombined bendamustine, prednisolone and lenalidomide (RBP) in refractory or relapsed multiple myeloma. First results of a phase I clinical trial [abstract]Blood (ASH Annual Meeting Abstracts)2010116211971
- van de DonkNWWittebolSMinnemaMCLokhorstHMLenalidomide (Revlimid) combined with continuous oral cyclophosphamide (endoxan) and prednisone (REP) is effective in lenalidomide/dexamethasone-refractory myelomaBr J Haematol2010148233533720085583
- MorganGJScheySAWuPLenalidomide (Revlimid), in combination with cyclophosphamide and dexamethasone (RCD), is an effective and tolerated regimen for myeloma patientsBr J Haematol2007137326826917408469
- ScheySAMorganGJRamasamyKThe addition of cyclophosphamide to lenalidomide and dexamethasone in multiply relapsed/refractory myeloma patients; a phase I/II studyBr J Haematol2010150332633320553268
- ReeceDEMasih-KhanEKhanAPhase I-II trial of oral cyclophosphamide, prednisone and lenalidomide (Revlimid(R)) (CPR) for the treatment of patients with relapsed and refractory multiple myeloma [abstract]Blood (ASH Annual Meeting Abstracts)2010116213055
- RichardsonPGWellerEJagannathSMulticenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myelomaJ Clin Oncol200927345713571919786667
- RichardsonPGJagannathSJakubowiakAJPhase II trial of lenalidomide, bortezomib, and dexamethasone in patients (pts) with relapsed and relapsed/refractory multiple myeloma (MM): updated efficacy and safety data after >2 years of follow-up [abstract]Blood (ASH Annual Meeting Abstracts)2010116213049
- DimopoulosMAKastritisEChristoulasDTreatment of patients with relapsed/refractory multiple myeloma with lenalidomide and dexamethasone with or without bortezomib: prospective evaluation of the impact of cytogenetic abnormalities and of previous therapiesLeukemia201024101769177820739955
- BelhadjKAmraouiKSafarVLenalidomide plus bortezomib and dexamethasone (RVD) followed by lenalidomide plus dexamethasone as salvage treatment for myeloma patients in first relapse after autologous stem cell transplantation. Single institution experience [abstract]Blood (ASH Annual Meeting Abstracts)2011118215143
- BerensonJRYellinOCartmellADA phase II study of pegylated liposomal doxorubicin (PLD), bortezomib, dexamethasone and lenalidomide (DVD-R) for patients with relapsed/refractory (R/R) multiple myeloma (MM) [abstract]Blood (ASH Annual Meeting Abstracts)2010116213044
- NiesvizkyRWangLOrlowskiRZPhase Ib multicenter dose escalation study of carfilzomib plus lenalidomide and low dose dexamethasone (CRd) in relapsed and refractory multiple myeloma (MM) [abstract]Blood (ASH Annual Meeting Abstracts)1120200911422304
- PalumboALaroccaAFalcoPLenalidomide, melphalan, prednisone and thalidomide (RMPT) for relapsed/refractory multiple myelomaLeukemia20102451037104220376079
- ShahJJOrlowskiRZAlexanianRPhase I trial of the combination of lenalidomide, thalidomide and dexamethasone in relapsed/refractory multiple myeloma [abstract]Blood (ASH Annual Meeting Abstracts)2010116211948
- RajeNKumarSHideshimaTCombination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myelomaBlood2004104134188419315319277
- HofmeisterCCYangXPichiorriFPhase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoproteinJ Clin Oncol201129253427343421825263
- MahindraARichardsonPGHariPUpdated results of a phase I study of RAD001 in combination with lenalidomide in patients with relapsed or refractory multiple myeloma with pharmacodynamic and pharmacokinetic analysis [abstract]Blood (ASH Annual Meeting Abstracts)2010116213051
- RichardsonPWeberDMitsiadesCSA phase I study of vorinostat, lenalidomide, and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: excellent tolerability and promising activity in a heavily pretreated population [abstract]Blood (ASH Annual Meeting Abstracts)2010116211951
- RichterJRBilottiEMcBrideLSalvage therapy with vorinostat, lenalidomide, and dexamethasone (ZRD) in lenalidomide/dexamethasone relapsed/refractory multiple myeloma [abstract]Blood (ASH Annual Meeting Abstracts)2011118213986
- JakubowiakAJRichardsonPGZimmermanTMFinal phase I results of perifosine in combination with lenalidomide and dexamethasone in patients with relapsed or refractory multiple myeloma (MM) [abstract]Blood (ASH Annual Meeting Abstracts)2010116213064
- QuachHRitchieDStewartAKMechanism of action of immunomodulatory drugs (IMiDS) in multiple myelomaLeukemia2010241223219907437
- HayashiTHideshimaTAkiyamaMMolecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical applicationBr J Haematol2005128219220315638853
- van de DonkNWKampsSMutisTLokhorstHMMonoclonal antibody-based therapy as a new treatment strategy in multiple myelomaLeukemia201226219921321852787
- LonialSJakubowiakAJJagannathSA phase 2 study of elotuzumab in combination with lenalidomide and low-dose dexamethasone in patients with relapsed/refractory multiple myeloma [abstract]Blood (ASH Annual Meeting Abstracts)201111821303
- LonialSVijRHarousseauJLElotuzumab in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myelomaJ Clin Oncol201230161953195922547589
- BerdejaJGAilawadhiSNiesvizkyRPhase I study of lorvotuzumab mertansine (IMGN901) in combination with lenalidomide and dexamethasone in patients with CD56-positive relapsed or relapsed/refractory multiple myeloma – a preliminary safety and efficacy analysis of the combination [abstract]Blood (ASH Annual Meeting Abstracts)2010116211934
- AguraENiesvizkyRMatousJDacetuzumab (SGN-40), lenalidomide, and weekly dexamethasone in relapsed or refractory multiple myeloma: multiple responses observed in a phase 1b study [abstract]Blood (ASH Annual Meeting Abstracts)2009114222870
- ZhangSLiangJChenLEnhanced NK cell mediated cytotoxicity against multiple myeloma (MM) cells by the combination of anti-KIR (1-7F9) monoclonal antibody (mAb) and lenalidomide [abstract]AACR Meeting Abstracts20092_Annual_Meeting3245
- SakamakiIKaplanBChaS-CQinHKwakLWPotent immunomodulatory effects of lenalidomide on effector T cells and Treg improve the effectiveness of a therapeutic lymphoma vaccine [abstract]Blood (ASH Annual Meeting Abstracts)201111821108
- LuptakovaKGlotzbeckerBMillsHLenalidomide decreases PD-1 expression, depletes regulatory T-cells and improves cellular response to a multiple myeloma/dendritic cell fusion vaccine in vitro [abstract]Blood (ASH Annual Meeting Abstracts)201011621492
- NoonanKRudrarajuLFergusonALenalidomide-induced immunomodulation in multiple myeloma: impact on vaccines and antitumor responsesClin Cancer Res20121851426143422241792
- van de DonkNWKrogerNHegenbartURemarkable activity of novel agents bortezomib and thalidomide in patients not responding to donor lymphocyte infusions following nonmyeloablative allogeneic stem cell transplantation in multiple myelomaBlood200610783415341616597603
- KrogerNBadbaranALioznovMPost-transplant immunotherapy with donor-lymphocyte infusion and novel agents to upgrade partial into complete and molecular remission in allografted patients with multiple myelomaExp Hematol200937779179819487069
- MinnemaMCvan der VeerMSAartsTEmmelotMMutisTLokhorstHMLenalidomide alone or in combination with dexamethasone is highly effective in patients with relapsed multiple myeloma following allogeneic stem cell transplantation and increases the frequency of CD4+Foxp3+ T cellsLeukemia200923360560718784738
- KneppersEvan der HoltBKerstenMJLenalidomide maintenance after nonmyeloablative allogeneic stem cell transplantation in multiple myeloma is not feasible: results of the HOVON 76 TrialBlood201111892413241921690556
- El-CheikhJCrocchioloRFurstSLenalidomide plus donor-lymphocytes infusion after allogeneic stem-cell transplantation with reduced-intensity conditioning in patients with high-risk multiple myelomaExp Hematol201240752152722446605
- KumarSKRajkumarSVDispenzieriAImproved survival in multiple myeloma and the impact of novel therapiesBlood200811152516252017975015
- PalumboAAndersonKMultiple myelomaN Engl J Med2011364111046106021410373
- PalumboABringhenSLudwigHPersonalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN)Blood2011118174519452921841166
- QuachHFernyhoughLHendersonRLower-dose lenalidomide and dexamethasone reduces toxicity without compromising efficacy in patients with relapsed/refractory myeloma, who are aged ≥60 years or have renal impairment: planned interim results of a prospective multicentre phase II trial [abstract]Blood (ASH Annual Meeting Abstracts)2010116211961
- DimopoulosMATerposEGoldschmidtHAlegreAMarkTNiesvizkyRTreatment with lenalidomide and dexamethasone in patients with multiple myeloma and renal impairmentCancer Treat Rev5182012 [Epub ahead of print.]
- NiesvizkyRNaibTChristosPJLenalidomide-induced myelosuppression is associated with renal dysfunction: adverse events evaluation of treatment-naive patients undergoing front-line lenalidomide and dexamethasone therapyBr J Haematol2007138564064317686058
- DimopoulosMAlegreAStadtmauerEAThe efficacy and safety of lenalidomide plus dexamethasone in relapsed and/or refractory multiple myeloma patients with impaired renal functionCancer2010116163807381420564094
- KleberMIhorstGUdiJKochBWaschREngelhardtMPrognostic risk factor evaluation in patients with relapsed or refractory multiple myeloma receiving lenalidomide treatment: analysis of renal function by eGFR and of additional comorbidities by comorbidity appraisalClin Lymphoma Myeloma Leuk2012121384822054851
- DimopoulosMAChristoulasDRoussouMLenalidomide and dexamethasone for the treatment of refractory/relapsed multiple myeloma: dosing of lenalidomide according to renal function and effect on renal impairmentEur J Haematol20108511520192988
- de la RubiaJRoigMIbanezAActivity and safety of lenalidomide and dexamethasone in patients with multiple myeloma requiring dialysis: a Spanish multicenter retrospective studyEur J Haematol201085436336520662900
- PalumboABladeJBoccadoroMHow to manage neutropenia in multiple myelomaClin Lymphoma Myeloma Leuk201212151122178143
- BennettCLAngelottaCYarnoldPRThalidomide- and lenalidomide-associated thromboembolism among patients with cancerJAMA2006296212558256017148721
- ZonderJABarlogieBDurieBGMcCoyJCrowleyJHusseinMAThrombotic complications in patients with newly diagnosed multiple myeloma treated with lenalidomide and dexamethasone: benefit of aspirin prophylaxisBlood20061081403 author reply 40416790586
- KnightRDeLapRJZeldisJBLenalidomide and venous thrombosis in multiple myelomaN Engl J Med2006354192079208016687729
- PalumboARajkumarSVDimopoulosMAfor International Myeloma Working GroupPrevention of thalidomide- and lenalidomide-associated thrombosis in myelomaLeukemia200822241442318094721
- LaroccaACavalloFBringhenSAspirin or enoxaparin thromboprophylaxis for patients with newly diagnosed multiple myeloma treated with lenalidomideBlood20121194933939 quiz 109321835953
- LonialSRichardsonPGSan MiguelJCharacterisation of haematological profiles and low risk of thromboembolic events with bortezomib in patients with relapsed multiple myelomaBr J Haematol2008143222222918713253
- Pineda-RomanMZangariMvan RheeFVTD combination therapy with bortezomib-thalidomide-dexamethasone is highly effective in advanced and refractory multiple myelomaLeukemia20082271419142718432260
- CiolliSLeoniFCasiniCBreschiCSantiniVBosiAThe addition of liposomal doxorubicin to bortezomib, thalidomide and dexamethasone significantly improves clinical outcome of advanced multiple myelomaBr J Haematol2008141681481918410447
- CiolliSLeoniFGigliFRigacciLBosiALow dose Velcade, thalidomide and dexamethasone (LD-VTD): an effective regimen for relapsed and refractory multiple myeloma patientsLeuk Lymphoma200647117117316321846
- PalumboAAmbrosiniMTBenevoloGfor Italian Multiple Myeloma Network, Gruppo Italiano Malattie Ematologicche dell’AdultoBortezomib, melphalan, prednisone, and thalidomide for relapsed multiple myelomaBlood200710972767277217148584
- TerposEKastritisERoussouMThe combination of bortezomib, melphalan, dexamethasone and intermittent thalidomide is an effective regimen for relapsed/refractory myeloma and is associated with improvement of abnormal bone metabolism and angiogenesisLeukemia200822122247225618769451
- ZangariMFinkLZhanFTricotGLow venous thromboembolic risk with bortezomib in multiple myeloma and potential protective effect with thalidomide/lenalidomide-based therapy: review of data from phase 3 trials and studies of novel combination regimensClin Lymphoma Myeloma Leuk201111222823621575928
- ZangariMTricotGPolavaramLSurvival effect of venous thromboembolism in patients with multiple myeloma treated with lenalidomide and high-dose dexamethasoneJ Clin Oncol201028113213519901114
- RajkumarSVHaymanSRLacyMQCombination therapy with lenalidomide plus dexamethasone (Rev/Dex) for newly diagnosed myelomaBlood2005106134050405316118317
- KleinUKoselyFHillengassJEffective prophylaxis of thromboembolic complications with low molecular weight heparin in relapsed multiple myeloma patients treated with lenalidomide and dexamethasoneAnn Hematol2009881677118668241
- PalumboADelforgeMCatalanoJA phase 3 study evaluating the efficacy and safety of lenalidomide combined with melphalan and prednisone In patients ≥ 65 years with newly diagnosed multiple myeloma (NDMM): continuous use of lenalidomide vs fixed-duration regimens [abstract]Blood (ASH Annual Meeting Abstracts)201011621622
- PalumboAHajekRDelforgeMfor MM-015 InvestigatorsContinuous lenalidomide treatment for newly diagnosed multiple myelomaN Engl J Med2012366191759176922571200
- AttalMLauwersVcMaritGMaintenance treatment with lenalidomide after transplantation for MYELOMA: final analysis of the IFM 2005–2002 [abstract]Blood (ASH Annual Meeting Abstracts)201011621310
- McCarthyPOwzarKAndersonKPhase III intergroup study of lenalidomide versus placebo maintenance therapy following single autologous stem cell transplant (ASCT) for multiple myeloma (MM): CALGB ECOG BMT-CTN 100104Haematologica201196s1S23
- AttalMLauwers-CancesVMaritGfor IFM InvestigatorsLenalidomide maintenance after stem-cell transplantation for multiple myelomaN Engl J Med2012366191782179122571202
- McCarthyPLOwzarKHofmeisterCCLenalidomide after stem-cell transplantation for multiple myelomaN Engl J Med2012366191770178122571201
- DimopoulosMARichardsonPGBrandenburgNA review of second primary malignancy in patients with relapsed or refractory multiple myeloma treated with lenalidomideBlood2012119122764276722323483
- DimopoulosMAPalumboAAttalMfor European Myeloma NetworkOptimizing the use of lenalidomide in relapsed or refractory multiple myeloma: consensus statementLeukemia201125574976021293488
- BarosiGMerliniGBillioASIE, SIES, GITMO evidence-based guidelines on novel agents (thalidomide, bortezomib, and lenalidomide) in the treatment of multiple myelomaAnn Hematol201291687588822476884
- KumarSKLeeJHLahuertaJJfor International Myeloma Working GroupRisk of progression and survival in multiple myeloma relapsing after therapy with IMiDs and bortezomib: a multicenter international myeloma working group studyLeukemia201226114915721799510
- van de DonkNWLokhorstHMDimopoulosMTreatment of relapsed and refractory multiple myeloma in the era of novel agentsCancer Treat Rev201137426628320863623