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Original Research

Downregulated lncRNA SNHG18 Suppresses the Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma and Meditates the Antitumor Effect of Oleanolic Acid

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Pages 687-695 | Published online: 18 Feb 2022

References

  • Chen Y, Tian Z. HBV-induced immune imbalance in the development of HCC. Front Immunol. 2019;10:2048. doi:10.3389/fimmu.2019.02048
  • Xie Y. Hepatitis B virus-associated hepatocellular carcinoma. Adv Exp Med Biol. 2017;1018:11–21.
  • Luo P, Wu S, Yu Y, et al. Current status and perspective biomarkers in AFP negative HCC: towards screening for and diagnosing hepatocellular carcinoma at an earlier stage. Pathol Oncol Res. 2020;26(2):599–603. doi:10.1007/s12253-019-00585-5
  • Wang W, Wei C. Advances in the early diagnosis of hepatocellular carcinoma. Genes Dis. 2020;7(3):308–319. doi:10.1016/j.gendis.2020.01.014
  • Pollier J, Goossens A. Oleanolic acid. Phytochemistry. 2012;77:10–15. doi:10.1016/j.phytochem.2011.12.022
  • Zhou R, Zhang Z, Zhao L, et al. Inhibition of mTOR signaling by oleanolic acid contributes to its anti-tumor activity in osteosarcoma cells. J Orthop Res. 2011;29(6):846–852. doi:10.1002/jor.21311
  • Wang H, Zhong W, Zhao J, et al. Oleanolic acid inhibits epithelial-mesenchymal transition of hepatocellular carcinoma by promoting iNOS dimerization. Mol Cancer Ther. 2019;18(1):62–74. doi:10.1158/1535-7163.MCT-18-0448
  • Zhou W, Zeng X, Wu X. Effect of oleanolic acid on apoptosis and autophagy of SMMC-7721 hepatoma cells. Med Sci Monit. 2020;26:e921606. doi:10.12659/MSM.921606
  • Chaturvedi VK, Singh A, Dubey SK, Hetta HF, John J, Singh MP. Molecular mechanistic insight of hepatitis B virus mediated hepatocellular carcinoma. Microb Pathog. 2019;128:184–194. doi:10.1016/j.micpath.2019.01.004
  • Zhao X, Liu M, Li D. Oleanolic acid suppresses the proliferation of lung carcinoma cells by miR-122/Cyclin G1/MEF2D axis. Mol Cell Biochem. 2015;400(1–2):1–7. doi:10.1007/s11010-014-2228-7
  • Han D, Zhang X, Zhang J, et al. Oleanolic acid suppresses vascular smooth muscle cell proliferation by increasing lincRNA-p21 expression. Oncol Lett. 2016;12(5):3519–3522. doi:10.3892/ol.2016.5096
  • Liu XF, Thin KZ, Ming XL, et al. Small nucleolar RNA host gene 18 acts as a tumor suppressor and a diagnostic indicator in hepatocellular carcinoma. Technol Cancer Res Treat. 2018;17:1533033818794494. doi:10.1177/1533033818794494
  • Huang LJ, Shen Y, Bai J, et al. High expression levels of long noncoding RNA small nucleolar RNA host gene 18 and semaphorin 5A indicate poor prognosis in multiple myeloma. Acta Haematol. 2020;143(3):279–288. doi:10.1159/000502404
  • Zheng R, Yao Q, Ren C, et al. Upregulation of long noncoding RNA small nucleolar RNA host gene 18 promotes radioresistance of glioma by repressing semaphorin 5A. Int J Radiat Oncol Biol Phys. 2016;96(4):877–887. doi:10.1016/j.ijrobp.2016.07.036
  • Bao Y, Zhang S, Chen Z, et al. Synergistic chemotherapy for breast cancer and breast cancer brain metastases via paclitaxel-loaded oleanolic acid nanoparticles. Mol Pharm. 2020;17(4):1343–1351. doi:10.1021/acs.molpharmaceut.0c00044
  • Niu G, Sun L, Pei Y, Wang D. Oleanolic acid inhibits colorectal cancer angiogenesis by blocking the VEGFR2 signaling pathway. Anticancer Agents Med Chem. 2018;18(4):583–590. doi:10.2174/1871520617666171020124916
  • Shopit A, Li X, Tang Z, et al. miR-421 up-regulation by the oleanolic acid derivative K73-03 regulates epigenetically SPINK1 transcription in pancreatic cancer cells leading to metabolic changes and enhanced apoptosis. Pharmacol Res. 2020;161:105130. doi:10.1016/j.phrs.2020.105130
  • Liu J, Zheng L, Zhong J, Wu N, Liu G, Lin X. Oleanolic acid induces protective autophagy in cancer cells through the JNK and mTOR pathways. Oncol Rep. 2014;32(2):567–572. doi:10.3892/or.2014.3239
  • Li YW, Yang FC, Lu HQ, Zhang JS. Hepatocellular carcinoma and hepatitis B surface protein. World J Gastroenterol. 2016;22(6):1943–1952. doi:10.3748/wjg.v22.i6.1943
  • Tong S, Revill P. Overview of hepatitis B viral replication and genetic variability. J Hepatol. 2016;64(1 Suppl):S4–S16. doi:10.1016/j.jhep.2016.01.027
  • Feng J, Yang G, Liu Y, et al. LncRNA PCNAP1 modulates hepatitis B virus replication and enhances tumor growth of liver cancer. Theranostics. 2019;9(18):5227–5245. doi:10.7150/thno.34273
  • Zheng R, Yao Q, Li X, Xu B. Long noncoding ribonucleic acid SNHG18 promotes glioma cell motility via disruption of alpha-enolase nucleocytoplasmic transport. Front Genet. 2019;10:1140. doi:10.3389/fgene.2019.01140
  • Fattovich G, Stroffolini T, Zagni I, Donato F. Hepatocellular carcinoma in cirrhosis: incidence and risk factors. Gastroenterology. 2004;127(5 Suppl 1):S35–S50. doi:10.1053/j.gastro.2004.09.014
  • Kanda T, Goto T, Hirotsu Y, Moriyama M, Omata M. Molecular mechanisms driving progression of liver cirrhosis towards hepatocellular carcinoma in chronic hepatitis B and C infections: a review. Int J Mol Sci. 2019;20(6):1358. doi:10.3390/ijms20061358
  • Daoud A, Teeter L, Ghobrial RM, et al. Transplantation for hepatocellular carcinoma: is there a tumor size limit? Transplant Proc. 2018;50(10):3577–3581. doi:10.1016/j.transproceed.2018.04.038
  • Huang WJ, Jeng YM, Lai HS, Sheu FY, Lai PL, Yuan RH. Tumor size is a major determinant of prognosis of resected stage I hepatocellular carcinoma. Langenbecks Arch Surg. 2015;400(6):725–734. doi:10.1007/s00423-015-1329-4
  • Kim SJ, Lee KK, Kim DG. Tumor size predicts the biological behavior and influence of operative modalities in hepatocellular carcinoma. Hepato-gastroenterology. 2010;57(97):121–126.
  • Liu M, Yan Q, Sun Y, et al. A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets. Proc Natl Acad Sci U S A. 2020;117(11):6103–6113. doi:10.1073/pnas.1912146117
  • Zhang W, Mu D, Feng K. Hierarchical potential differentiation of liver cancer stem cells. Adv Clin Exp Med. 2017;26(7):1137–1141. doi:10.17219/acem/66343