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Review

MicroRNA dysregulation as a prognostic biomarker in colorectal cancer

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Pages 405-422 | Published online: 14 Oct 2014

References

  • JemalABrayFCenterMMFerlayJWardEFormanDGlobal cancer statisticsCA Cancer J Clin2011612699021296855
  • SungJJLauJYYoungGPAsia Pacific Working Group on Colorectal CancerAsia Pacific consensus recommendations for colorectal cancer screeningGut20085781166117618628378
  • WolpinBMMayerRJSystemic treatment of colorectal cancerGastroenterology200813451296131018471507
  • WangYJatkoeTZhangYGene expression profiles and molecular markers to predict recurrence of Dukes’ B colon cancerJ Clin Oncol20042291564157115051756
  • BartelDPMicroRNAs: genomics, biogenesis, mechanism, and functionCell2004116228129714744438
  • FriedmanRCFarhKKBurgeCBBartelDPMost mammalian mRNAs are conserved targets of microRNAsGenome Res20091919210518955434
  • LuJGetzGMiskaEAMicroRNA expression profiles classify human cancersNature2005435704383483815944708
  • VoliniaSCalinGALiuCGA microRNA expression signature of human solid tumors defines cancer gene targetsProc Natl Acad Sci U S A200610372257226116461460
  • DongYWuWKWuCWSungJJYuJNgSSMicroRNA dysregulation in colorectal cancer: a clinical perspectiveBr J Cancer2011104689389821364594
  • WuWKLawPTLeeCWMicroRNA in colorectal cancer: from benchtop to bedsideCarcinogenesis201132324725321081475
  • de KrijgerIMekenkampLJPuntCJNagtegaalIDMicroRNAs in colorectal cancer metastasisJ Pathol2011224443844721706478
  • ScheeKBoyeKAbrahamsenTWFodstadØFlatmarkKClinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancerBMC Cancer20121250523121918
  • ScheeKLorenzSWorrenMMDeep sequencing the microRNA transcriptome in colorectal cancerPLoS One201386e6616523824282
  • SchetterAJLeungSYSohnJJMicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinomaJAMA2008299442543618230780
  • NielsenBSJørgensenSFogJUHigh levels of microRNA-21 in the stroma of colorectal cancers predict short disease-free survival in stage II colon cancer patientsClin Exp Metastasis2011281273821069438
  • ShibuyaHIinumaHShimadaRHoriuchiAWatanabeTClinicopathological and prognostic value of microRNA-21 and microRNA-155 in colorectal cancerOncology2010793–431332021412018
  • SchetterAJNguyenGHBowmanEDAssociation of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinomaClin Cancer Res200915185878588719737943
  • ZhangJXSongWChenZHPrognostic and predictive value of a microRNA signature in stage II colon cancer: a microRNA expression analysisLancet Oncol201314131295130624239208
  • KuldaVPestaMTopolcanORelevance of miR-21 and miR-143 expression in tissue samples of colorectal carcinoma and its liver metastasesCancer Genet Cytogenet2010200215416020620599
  • Valladares-AyerbesMBlancoMHazMPrognostic impact of disseminated tumor cells and microRNA-17–92 cluster deregulation in gastrointestinal cancerInt J Oncol20113951253126421743960
  • AkçakayaPEkelundSKolosenkoImiR-185 and miR-133b deregulation is associated with overall survival and metastasis in colorectal cancerInt J Oncol201139231131821573504
  • LiuGHZhouZGChenRSerum miR-21 and miR-92a as biomarkers in the diagnosis and prognosis of colorectal cancerTumour Biol20133442175218123625654
  • MenéndezPPadillaDVillarejoPPrognostic implications of serum microRNA-21 in colorectal cancerJ Surg Oncol2013108636937323970420
  • SlabyOSvobodaMFabianPAltered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancerOncology2007725–639740218196926
  • TibshiraniRRegression shrinkage and selection via the lassoJ R Statist Soc B1996581267288
  • GaedckeJGradeMCampsJThe rectal cancer microRNAome – microRNA expression in rectal cancer and matched normal mucosaClin Cancer Res201218184919493022850566
  • SlatteryMLWolffEHoffmanMDPellattDFMilashBWolffRKMicroRNAs and colon and rectal cancer: differential expression by tumor location and subtypeGenes Chromosomes Cancer201150319620621213373
  • YamamichiNShimomuraRInadaKLocked nucleic acid in situ hybridization analysis of miR-21 expression during colorectal cancer developmentClin Cancer Res200915124009401619509156
  • BullockMDPickardKMNielsenBSPleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progressionCell Death Dis20134e68423788041
  • BullockMPickardKNielsenBSDeregulated stromal microRNA-21 and promotion of metastatic progression in colorectal cancer. Proceedings of the Spring Meeting for Clinician Scientists in Training, Academy of Medical Sciences’ Annual Spring Meeting; February 26, 2014: London, UKLancet2014383S30
  • FuJTangWDuPIdentifying microRNA-mRNA regulatory network in colorectal cancer by a combination of expression profile and bioinformatics analysisBMC Syst Biol201266822703586
  • BandrésECubedoEAgirreXIdentification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissuesMol Cancer200652916854228
  • ArndtGMDosseyLCullenLMCharacterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancerBMC Cancer2009937419843336
  • SlatteryMLWolffEHoffmanMDPellattDFMilashBWolffRKMicroRNAs and colon and rectal cancer: differential expression by tumor location and subtypeGenes Chromosomes Cancer201150319620621213373
  • HuangZHuangDNiSPengZShengWDuXPlasma microRNAs are promising novel biomarkers for early detection of colorectal cancerInt J Cancer2010127111812619876917
  • Brunet VegaAPericayCMoyaImicroRNA expression profile in stage III colorectal cancer: circulating miR-18a and miR-29a as promising biomarkersOncol Rep201330132032623673725
  • WangLGGuJSerum microRNA-29a is a promising novel marker for early detection of colorectal liver metastasisCancer Epidemiol2012361e61e6722018950
  • TangWZhuYGaoJMicroRNA-29a promotes colorectal cancer metastasis by regulating matrix metalloproteinase 2 and E-cadherin via KLF4Br J Cancer2014110245045824281002
  • CroceCMHarrisCCSchetterAJinventorsMethod of diagnosing poor survival prognosis colon cancer using mir-29a United States Patent US 8338106 B212252012
  • FaltejskovaPBocanekOSachlovaMCirculating miR-17-3p, miR-29a, miR-92a and miR-135b in serum: Evidence against their usage as biomarkers in colorectal cancerCancer Biomark201212419920423568010
  • Weissmann-BrennerAKushnirMLithwick YanaiGTumor microRNA-29a expression and the risk of recurrence in stage II colon cancerInt J Oncol20124062097210322426940
  • LeeYYangXHuangYNetwork modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasisPLoS Comput Biol201064e100073020369013
  • KuoTYHsiEYangIPTsaiPCWangJYJuoSHComputational analysis of mRNA expression profiles identifies microRNA-29a/c as predictor of colorectal cancer early recurrencePLoS One201272e3158722348113
  • ChenYSongYWangZAltered expression of MiR-148a and MiR-152 in gastrointestinal cancers and its clinical significanceJ Gastrointest Surg20101471170117920422307
  • TakahashiMCuatrecasasMBalaguerFThe clinical significance of MiR-148a as a predictive biomarker in patients with advanced colorectal cancerPLoS One2012710e4668423056401
  • TsaiHLYangIPHuangCWClinical significance of microRNA-148a in patients with early relapse of stage II stage and III colorectal cancer after curative resectionTransl Res2013162425826823933284
  • LauPWGuileyKZDeNPotterCSCarragherBMacRaeIJThe molecular architecture of human DicerNat Struct Mol Biol201219443644022426548
  • CarthewRWSontheimerEJOrigins and mechanisms of miRNAs and siRNAsCell2009136464265519239886
  • KumarMSPesterREChenCYDicer1 functions as a haploinsufficient tumor suppressorGenes Dev200923232700270419903759
  • KumarMSLuJMercerKLGolubTRJacksTImpaired microRNA processing enhances cellular transformation and tumorigenesisNat Genet200739567367717401365
  • IliouMSda Silva-DizVCarmonaFJImpaired DICER1 function promotes stemness and metastasis in colon cancerOncogene201433304003401524096488
  • Al-MullaFAlFadhliSAl-HakimAHGoingJJBitarMSMetastatic recurrence of early-stage colorectal cancer is linked to loss of heterozygosity on chromosomes 4 and 14qJ Clin Pathol200659662463016731603
  • AkahaneTClinicopathological and prognostic significance of the microRNA processing enzyme DICER1 mRNA expression in colorectal cancer patientsMol Clin Oncol20131226727324649159
  • FaggadAKasajimaAWeichertWDown-regulation of the microRNA processing enzyme Dicer is a prognostic factor in human colorectal cancerHistopathology201261455256122716222
  • StratmannJWangCJGnosaSDicer and miRNA in relation to clinicopathological variables in colorectal cancer patientsBMC Cancer20111134521827717
  • ChioseaSAcquafondataMLuoJKuanSSeethalaRDICER1 and PRKRA in colon adenocarcinomaBiomark Insights2008325325819578509
  • PapachristouDJKorpetinouAGiannopoulouEExpression of the ribonucleases Drosha, Dicer, and Ago2 in colorectal carcinomasVirchows Arch2011459443144021769619
  • FaberCHorstDHlubekFKirchnerTOverexpression of Dicer predicts poor survival in colorectal cancerEur J Cancer20114791414141921345667
  • YuZLiZJolicoeurNAberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancersNucleic Acids Res200735134535454117584784
  • ClopAMarcqFTakedaHA mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheepNat Genet200638781381816751773
  • JohnsonSMGrosshansHShingaraJRAS is regulated by the let-7 microRNA familyCell2005120563564715766527
  • ChinLJRatnerELengSA SNP in a let-7 microRNA complementary site in the KRAS 3′ untranslated region increases non-small cell lung cancer riskCancer Res200868208535854018922928
  • ShaDLeeAMShiQAssociation study of the let-7 miRNA-complementary site variant in the 3′ untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial)Clin Cancer Res201420123319332724727325
  • KjersemJBIkdahlTGurenTLet-7 miRNA-binding site polymorphism in the KRAS 3′UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin ± cetuximabBMC Cancer20121253423167843
  • SmitsKMParanjapeTNallurSA let-7 microRNA SNP in the KRAS 3′UTR is prognostic in early-stage colorectal cancerClin Cancer Res201117247723773121994416
  • GrazianoFCanestrariELoupakisFGenetic modulation of the Let-7 microRNA binding to KRAS 3′-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecanPharmacogenomics J201010545846420177422
  • RyanBMRoblesAIHarrisCCKRAS-LCS6 genotype as a prognostic marker in early-stage CRC – letterClin Cancer Res2012181234878 author reply 348922669132
  • YeYMadisonBWuXRustgiAKA LIN28B polymorphism predicts for colon cancer survivalCancer Biol Ther201213141390139523052130
  • ZhangWWinderTNingYA let-7 microRNA-binding site polymorphism in 3′-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapyAnn Oncol201122110410920603437
  • RyanBMRoblesAIHarrisCCGenetic variation in microRNA networks: the implications for cancer researchNat Rev Cancer201010638940220495573
  • LinMGuJEngCGenetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patientsClin Cancer Res201218143982399122661538
  • LeeHCKimJGChaeYSPrognostic impact of microRNA-related gene polymorphisms on survival of patients with colorectal cancerJ Cancer Res Clin Oncol201013671073107820044760
  • XingJWanSZhouFGenetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancerCancer Epidemiol Biomarkers Prev201221121722722028396
  • JazdzewskiKMurrayELFranssilaKJarzabBSchoenbergDRde la ChapelleACommon SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinomaProc Natl Acad Sci U S A2008105207269727418474871
  • O’ConnellRMRaoDSBaltimoreDmicroRNA regulation of inflammatory responsesAnnu Rev Immunol20123029531222224773
  • ChaeYSKimJGLeeSJA miR-146a polymorphism (rs2910164) predicts risk of and survival from colorectal cancerAnticancer Res20133383233323923898084
  • JangMJKimJWMinKTJeonYJOhDKimNKPrognostic significance of microRNA gene polymorphisms in patients with surgically resected colorectal cancerExp Ther Med2011261127113222977632
  • PinoMSChungDCThe chromosomal instability pathway in colon cancerGastroenterology201013862059207220420946
  • GryfeRKimHHsiehETTumor microsatellite instability and clinical outcome in young patients with colorectal cancerN Engl J Med20003422697710631274
  • LanzaGFerracinMGafàRmRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerMol Cancer200765417716371
  • SchepelerTReinertJTOstenfeldMSDiagnostic and prognostic microRNAs in stage II colon cancerCancer Res200868156416642418676867
  • SarverALFrenchAJBorralhoPMHuman colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative statesBMC Cancer2009940119922656
  • BalaguerFMoreiraLLozanoJJColorectal cancers with microsatellite instability display unique miRNA profilesClin Cancer Res201117196239624921844009
  • EarleJSLuthraRRomansAAssociation of microRNA expression with microsatellite instability status in colorectal adenocarcinomaJ Mol Diagn201012443344020413677
  • NishidaNYamashitaSMimoriKMicroRNA-10b is a prognostic indicator in colorectal cancer and confers resistance to the chemotherapeutic agent 5-fluorouracil in colorectal cancer cellsAnn Surg Oncol20121993065307122322955
  • QianJJiangBLiMChenJFangMPrognostic significance of microRNA-16 expression in human colorectal cancerWorld J Surg201337122944294924045965
  • YuGTangJQTianMLPrognostic values of the miR-17–92 cluster and its paralogs in colon cancerJ Surg Oncol2012106323223722065543
  • WuCWDongYJLiangQYMicroRNA-18a attenuates DNA damage repair through suppressing the expression of ataxia telangiectasia mutated in colorectal cancerPLoS One201382e5703623437304
  • KahlertCKluppFBrandKInvasion front-specific expression and prognostic significance of microRNA in colorectal liver metastasesCancer Sci2011102101799180721722265
  • ZhangGXiaSTianHLiuZZhouTClinical significance of miR-22 expression in patients with colorectal cancerMed Oncol20122953108311222492279
  • ZhouTZhangGLiuZXiaSTianHOverexpression of miR-92a correlates with tumor metastasis and poor prognosis in patients with colorectal cancerInt J Colorectal Dis2013281192422772712
  • XiaoZGDengZSZhangYDZhangYHuangZCClinical significance of microRNA-93 downregulation in human colon cancerEur J Gastroenterol Hepatol201325329630123354160
  • DíazRSilvaJGarcíaJMDeregulated expression of miR-106a predicts survival in human colon cancer patientsGenes Chromosomes Cancer200847979480218521848
  • WangMJLiYWangRDownregulation of microRNA-124 is an independent prognostic factor in patients with colorectal cancerInt J Colorectal Dis201328218318922885837
  • NishidaNYokoboriTMimoriKMicroRNA miR-125b is a prognostic marker in human colorectal cancerInt J Oncol20113851437144321399871
  • HansenTFSørensenFBLindebjergJJakobsenAThe predictive value of microRNA-126 in relation to first line treatment with capecitabine and oxaliplatin in patients with metastatic colorectal cancerBMC Cancer2012128322397399
  • TakahashiYIwayaTSawadaGUp-regulation of NEK2 by microRNA-128 methylation is associated with poor prognosis in colorectal cancerAnn Surg Oncol201421120521224046120
  • MosakhaniNLahtiLBorzeIMicroRNA profiling predicts survival in anti-EGFR treated chemorefractory metastatic colorectal cancer patients with wild-type KRAS and BRAFCancer Genet20122051154555123098991
  • PichlerMWinterEStotzMDown-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancerBr J Cancer2012106111826183222549179
  • DrebberULayMWedemeyerIAltered levels of the onco-microRNA 21 and the tumor-supressor microRNAs 143 and 145 in advanced rectal cancer indicate successful neoadjuvant chemoradiotherapyInt J Oncol201139240941521567082
  • NishimuraJHandaRYamamotoHmicroRNA-181a is associated with poor prognosis of colorectal cancerOncol Rep20122862221222623023298
  • WangXWangJMaHZhangJZhouXDownregulation of miR-195 correlates with lymph node metastasis and poor prognosis in colorectal cancerMed Oncol201229291992721390519
  • XiYFormentiniAChienMPrognostic values of microRNAs in colorectal cancerBiomark Insights2006211312118079988
  • MengXWuJPanCGenetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSODGastroenterology20131452426436. e123583431
  • KaraayvazMPalTSongBPrognostic significance of miR-215 in colon cancerClin Colorectal Cancer201110434034721752725
  • ChristensenLLTobiasenHHolmACOLOFOL steering groupMiRNA-362-3p induces cell cycle arrest through targeting of E2F1, USF2 and PTPN1 and is associated with recurrence of colorectal cancerInt J Cancer20131331677823280316
  • YamashitaSYamamotoHMimoriKMicroRNA-372 is associated with poor prognosis in colorectal cancerOncology201282420521222456107
  • YangIPTsaiHLHuangCWThe functional significance of microRNA-29c in patients with colorectal cancer: a potential circulating biomarker for predicting early relapsePLoS One201386e6684223840538
  • ChengHZhangLCogdellDECirculating plasma MiR-141 is a novel biomarker for metastatic colon cancer and predicts poor prognosisPLoS One201163e1774521445232
  • PuXXHuangGLGuoHQCirculating miR-221 directly amplified from plasma is a potential diagnostic and prognostic marker of colorectal cancer and is correlated with p53 expressionJ Gastroenterol Hepatol201025101674168020880178