Cancer Management and Research, Volume 6, Issue (2014)

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Cancer Management and Research, Volume 6, Issue (2014)

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Case Report

Case Report
Marked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab
Steven Sorscher
Pages: 1-3
Published online: 11 Dec 2013
AbstractforMarked radiographic response of a HER-2-overexpressing biliary cancer to trastuzumab | Full Text | References | PDF (367.2 KB)
  • 73 Views
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Open Access

Review

Review Article
Real-world impact of education: treating patients with ipilimumab in a community practice setting
Blanca Ledezma & Annie Heng
Pages: 5-14
Published online: 21 Dec 2013
AbstractforReal-world impact of education: treating patients with ipilimumab in a community practice setting | Full Text | References | PDF (832.1 KB)
  • 79 Views
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Open Access
Review Article
MicroRNA function and dysregulation in bone tumors: the evidence to date
Mary Nugent
Pages: 15-25
Published online: 30 Sep 2022
AbstractforMicroRNA function and dysregulation in bone tumors: the evidence to date | Full Text | References | PDF (312.4 KB)
  • 143 Views
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Open Access
Review Article
Developments in Burkitt’s lymphoma: novel cooperations in oncogenic MYC signaling
Lindsay C Spender & Gareth J Inman
Pages: 27-38
Published online: 30 Sep 2022
AbstractforDevelopments in Burkitt’s lymphoma: novel cooperations in oncogenic MYC signaling | Full Text | References | PDF (380.8 KB)
  • 113 Views
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Open Access
Review Article
Abiraterone in the treatment of metastatic castration-resistant prostate cancer
Elahe A Mostaghel
Pages: 39-51
Published online: 28 Jan 2014
AbstractforAbiraterone in the treatment of metastatic castration-resistant prostate cancer | Full Text | References | PDF (319.3 KB)
  • 298 Views
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Open Access
Review Article
Decitabine in the treatment of acute myeloid leukemia in elderly patients
Priya Malik & Amanda F Cashen
Pages: 53-61
Published online: 30 Sep 2022
AbstractforDecitabine in the treatment of acute myeloid leukemia in elderly patients | Full Text | References | PDF (233.1 KB)
  • 202 Views
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Open Access
Review Article
New modalities of cancer treatment for NSCLC: focus on immunotherapy
Marianne Davies
Pages: 63-75
Published online: 30 Sep 2022
AbstractforNew modalities of cancer treatment for NSCLC: focus on immunotherapy | Full Text | References | PDF (1.1 MB)
  • 318 Views
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Open Access
Review Article
DNA repair in cancer: emerging targets for personalized therapy
Rachel Abbotts, Nicola Thompson & Srinivasan Madhusudan
Pages: 77-92
Published online: 30 Sep 2022
AbstractforDNA repair in cancer: emerging targets for personalized therapy | Full Text | References | PDF (358.3 KB)
  • 180 Views
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Review Article

Review Article
Proactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management
Gazala Khan, Rebecca A Moss, Fadi Braiteh & Marc Saltzman
Pages: 93-103
Published online: 04 Mar 2014
AbstractforProactive strategies for regorafenib in metastatic colorectal cancer: implications for optimal patient management | Full Text | References | PDF (365 KB)
  • 105 Views
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Open Access
Review Article
Fertility preservation during cancer treatment: clinical guidelines
Kenny A Rodriguez-Wallberg & Kutluk Oktay
Pages: 105-117
Published online: 30 Sep 2022
AbstractforFertility preservation during cancer treatment: clinical guidelines | Full Text | References | PDF (688.2 KB)
  • 432 Views
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Open Access

Research Article

Article
Multiple neoplasms, single primaries, and patient survival
Magid H Amer
Pages: 119-134
Published online: 30 Sep 2022
AbstractforMultiple neoplasms, single primaries, and patient survival | Full Text | References | PDF (1.1 MB)
  • 143 Views
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Open Access

Review

Review Article
Chemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature
Andreas A Argyriou, Athanasios P Kyritsis, Thomas Makatsoris & Haralabos P Kalofonos
Pages: 135-147
Published online: 30 Sep 2022
AbstractforChemotherapy-induced peripheral neuropathy in adults: a comprehensive update of the literature | Full Text | References | PDF (290.4 KB)
  • 423 Views
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Open Access
Review Article
Malignant gliomas: current perspectives in diagnosis, treatment, and early response assessment using advanced quantitative imaging methods
Rafay Ahmed, Matthew J Oborski, Misun Hwang, Frank S Lieberman & James M Mountz
Pages: 149-170
Published online: 30 Sep 2022
AbstractforMalignant gliomas: current perspectives in diagnosis, treatment, and early response assessment using advanced quantitative imaging methods | Full Text | References | PDF (2.6 MB)
  • 274 Views
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Open Access
Review Article
Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells
Susumu Nakata, Emma Phillips & Violaine Goidts
Pages: 171-180
Published online: 30 Sep 2022
AbstractforEmerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells | Full Text | References | PDF (2.2 MB)
  • 138 Views
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Open Access

Original Research

Article
A randomized, placebo-controlled, four-period crossover, definitive QT study of the effects of APF530 exposure, high-dose intravenous granisetron, and moxifloxacin on QTc prolongation
Jay W Mason, Thomas E Moon, Erin O’Boyle & Albert Dietz
Pages: 181-190
Published online: 30 Sep 2022
AbstractforA randomized, placebo-controlled, four-period crossover, definitive QT study of the effects of APF530 exposure, high-dose intravenous granisetron, and moxifloxacin on QTc prolongation | Full Text | References | PDF (357.6 KB)
  • 98 Views
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Open Access
Article
Genetic factors and breast cancer laterality
Magid H Amer
Pages: 191-203
Published online: 30 Sep 2022
AbstractforGenetic factors and breast cancer laterality | Full Text | References | PDF (567.9 KB)
  • 226 Views
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Open Access

Review

Review Article
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
Antonio Díaz-López, Gema Moreno-Bueno & Amparo Cano
Pages: 205-216
Published online: 30 Sep 2022
AbstractforRole of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives | Full Text | References | PDF (313.9 KB)
  • 130 Views
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Open Access
Review Article
Future of bisphosphonates and denosumab for men with advanced prostate cancer
Maryam Iranikhah, Steve Stricker & Maisha Kelly Freeman
Pages: 217-224
Published online: 30 Sep 2022
AbstractforFuture of bisphosphonates and denosumab for men with advanced prostate cancer | Full Text | References | PDF (228.4 KB)
  • 84 Views
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Open Access
Review Article
Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer
Felicity EB May
Pages: 225-252
Published online: 30 Sep 2022
AbstractforNovel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer | Full Text | References | PDF (9 MB)
  • 336 Views
  • 4 CrossRef citations
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Open Access
Review Article
Presentation and management of docetaxel-related adverse effects in patients with breast cancer
Maria Y Ho & John R Mackey
Pages: 253-259
Published online: 30 Sep 2022
AbstractforPresentation and management of docetaxel-related adverse effects in patients with breast cancer | Full Text | References | PDF (201.5 KB)
  • 560 Views
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Open Access

Rapid Communication

Article
High plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy
Vikram Gota, Krunal Kavathiya, Kartik Doshi, Murari Gurjar, Solai E Damodaran, Vanita Noronha, Amit Joshi & Kumar Prabhash
Pages: 261-265
Published online: 30 Sep 2022
AbstractforHigh plasma exposure to pemetrexed leads to severe hyponatremia in patients with advanced non small cell lung cancer receiving pemetrexed-platinum doublet chemotherapy | Full Text | References | PDF (214.8 KB)
  • 60 Views
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Open Access

Original Research

Article
Molecular effects of bioactive fraction of Curcuma mangga (DLBS4847) as a downregulator of 5α-reductase activity pathways in prostatic epithelial cells
Agung Heru Karsono, Olivia Mayasari Tandrasasmita & Raymond R Tjandrawinata
Pages: 267-278
Published online: 30 Sep 2022
AbstractforMolecular effects of bioactive fraction of Curcuma mangga (DLBS4847) as a downregulator of 5α-reductase activity pathways in prostatic epithelial cells | Full Text | References | PDF (1.3 MB)
  • 138 Views
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Review

Review Article
Update on benefit of immunotherapy and targeted therapy in melanoma: the changing landscape
Neeharika Srivastava & David McDermott
Pages: 279-289
Published online: 30 Sep 2022
AbstractforUpdate on benefit of immunotherapy and targeted therapy in melanoma: the changing landscape | Full Text | References | PDF (1.6 MB)
  • 368 Views
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Open Access
Review Article
Prognostic stratification of colorectal cancer patients: current perspectives
Nora I Schneider & Cord Langner
Pages: 291-300
Published online: 30 Sep 2022
AbstractforPrognostic stratification of colorectal cancer patients: current perspectives | Full Text | References | PDF (2.3 MB)
  • 223 Views
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Open Access
Review Article
Computational prognostic indicators for breast cancer
Xinan Yang, Xindi Ai & John M Cunningham
Pages: 301-312
Published online: 30 Sep 2022
AbstractforComputational prognostic indicators for breast cancer | Full Text | References | PDF (335.7 KB)
  • 69 Views
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Open Access

Letter

Letter
Fertility preservation and GnRHa for chemotherapy: debate
Zeev Blumenfeld
Pages: 313-315
Published online: 30 Sep 2022
First Page PreviewforFertility preservation and GnRHa for chemotherapy: debate | Full Text | References | PDF (138.3 KB)
  • 73 Views
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Review

Review Article
Interstitial fluid flow in cancer: implications for disease progression and treatment
Jennifer M Munson & Adrian C Shieh
Pages: 317-328
Published online: 30 Sep 2022
AbstractforInterstitial fluid flow in cancer: implications for disease progression and treatment | Full Text | References | PDF (273.1 KB)
  • 461 Views
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Review Article
Palonosetron in the management of chemotherapy-induced nausea and vomiting in patients receiving multiple-day chemotherapy
Mary Lou Affronti & Joseph Bubalo
Pages: 329-337
Published online: 30 Sep 2022
AbstractforPalonosetron in the management of chemotherapy-induced nausea and vomiting in patients receiving multiple-day chemotherapy | Full Text | References | PDF (261.4 KB)
  • 85 Views
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Original Research

Article
Is extended-field concurrent chemoradiation an option for radiologic negative paraaortic lymph node, locally advanced cervical cancer?
Mushabbab Al Asiri, Mutahir A Tunio, Reham Mohamed, Yasser Bayoumi, Abdulrehman Alhadab, Rasha M Saleh, Muhannad Saud AlArifi & Abdelaziz Alobaid
Pages: 339-348
Published online: 30 Sep 2022
AbstractforIs extended-field concurrent chemoradiation an option for radiologic negative paraaortic lymph node, locally advanced cervical cancer? | Full Text | References | PDF (1.9 MB)
  • 118 Views
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Open Access

Review

Review Article
Treating advanced melanoma: current insights and opportunities
Michael Tronnier & Christina Mitteldorf
Pages: 349-356
Published online: 30 Sep 2022
AbstractforTreating advanced melanoma: current insights and opportunities | Full Text | References | PDF (1.3 MB)
  • 87 Views
  • 3 CrossRef citations
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Open Access
Review Article
Dexrazoxane for the treatment of chemotherapy-related side effects
Seppo W Langer
Pages: 357-363
Published online: 30 Sep 2022
AbstractforDexrazoxane for the treatment of chemotherapy-related side effects | Full Text | References | PDF (470 KB)
  • 316 Views
  • 1 CrossRef citations
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Open Access

Original Research

Article
Interpreting overall survival results when progression-free survival benefits exist in today’s oncology landscape: a metastatic renal cell carcinoma case study
Yiyun Tang, Paul Bycott, Örjan Åkerborg, Linus Jönsson, Sylvie Negrier & Connie Chen
Pages: 365-371
Published online: 30 Sep 2022
AbstractforInterpreting overall survival results when progression-free survival benefits exist in today’s oncology landscape: a metastatic renal cell carcinoma case study | Full Text | References | PDF (305.4 KB)
  • 105 Views
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Review

Review Article
The impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients
Hans Skovgaard Poulsen, Thomas Urup, Signe Regner Michaelsen, Mikkel Staberg, Mette Villingshøj & Ulrik Lassen
Pages: 373-387
Published online: 30 Sep 2022
AbstractforThe impact of bevacizumab treatment on survival and quality of life in newly diagnosed glioblastoma patients | Full Text | References | PDF (363.5 KB)
  • 144 Views
  • 4 CrossRef citations
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Open Access

Commentary

Article Commentary
Clinical implications of recent studies using mTOR inhibitors to treat advanced hormone receptor-positive breast cancer
Francis Arena
Pages: 389-395
Published online: 30 Sep 2022
AbstractforClinical implications of recent studies using mTOR inhibitors to treat advanced hormone receptor-positive breast cancer | Full Text | References | PDF (990.7 KB)
  • 77 Views
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Open Access

Review

Review Article
Targeting the MET receptor tyrosine kinase in non-small cell lung cancer: emerging role of tivantinib
Eberechi S Agwa & Patrick C Ma
Pages: 397-404
Published online: 30 Sep 2022
AbstractforTargeting the MET receptor tyrosine kinase in non-small cell lung cancer: emerging role of tivantinib | Full Text | References | PDF (220.5 KB)
  • 93 Views
  • 3 CrossRef citations
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Open Access
Review Article
MicroRNA dysregulation as a prognostic biomarker in colorectal cancer
Yujuan Dong, Jun Yu & Simon SM Ng
Pages: 405-422
Published online: 30 Sep 2022
AbstractforMicroRNA dysregulation as a prognostic biomarker in colorectal cancer | Full Text | References | PDF (391.5 KB)
  • 144 Views
  • 5 CrossRef citations
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Open Access
Review Article
Preventative therapies for healthy women at high risk of breast cancer
Ivana Sestak
Pages: 423-430
Published online: 30 Sep 2022
AbstractforPreventative therapies for healthy women at high risk of breast cancer | Full Text | References | PDF (250.1 KB)
  • 110 Views
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Original Research

Article
Higher susceptibility of NOD/LtSz-scid Il2rg−/− NSG mice to xenotransplanted lung cancer cell lines
Nobuhiro Kanaji, Akira Tadokoro, Kentaro Susaki, Saki Yokokura, Kiyomi Ohmichi, Reiji Haba, Naoki Watanabe, Shuji Bandoh, Tomoya Ishii, Hiroaki Dobashi & Takuya Matsunaga
Pages: 431-436
Published online: 30 Sep 2022
AbstractforHigher susceptibility of NOD/LtSz-scid Il2rg−/− NSG mice to xenotransplanted lung cancer cell lines | Full Text | References | PDF (886.8 KB)
  • 106 Views
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Open Access

Review

Review Article
A comprehensive review of nongenetic prognostic and predictive factors influencing the heterogeneity of outcomes in advanced non-small-cell lung cancer
Gebra Cuyún Carter, Amy M Barrett, James A Kaye, Astra M Liepa, Katherine B Winfree & William J John
Pages: 437-449
Published online: 30 Sep 2022
AbstractforA comprehensive review of nongenetic prognostic and predictive factors influencing the heterogeneity of outcomes in advanced non-small-cell lung cancer | Full Text | References | PDF (570.3 KB)
  • 105 Views
  • 3 CrossRef citations
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Open Access
Review Article
Single fraction radiotherapy versus multiple fraction radiotherapy for bone metastases in prostate cancer patients: comparative effectiveness
Frederick Yoon & Gerard C Morton
Pages: 451-457
Published online: 30 Sep 2022
AbstractforSingle fraction radiotherapy versus multiple fraction radiotherapy for bone metastases in prostate cancer patients: comparative effectiveness | Full Text | References | PDF (203.7 KB)
  • 69 Views
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Original Research

Article
Survival benefit of adjuvant radiotherapy in stage III and IV bladder cancer: results of 170 patients
Yasser Bayoumi, Tarek Heikal & Hossam Darweish
Pages: 459-465
Published online: 30 Sep 2022
AbstractforSurvival benefit of adjuvant radiotherapy in stage III and IV bladder cancer: results of 170 patients | Full Text | References | PDF (279.4 KB)
  • 84 Views
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Case Report

Case Report
Malignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review
Toni Pacioles, Rahul Seth, Cesar Orellana, Ivy John, Veera Panuganty & Ruban Dhaliwal
Pages: 467-473
Published online: 30 Sep 2022
AbstractforMalignant phyllodes tumor of the breast presenting with hypoglycemia: a case report and literature review | Full Text | References | PDF (929.1 KB)
  • 123 Views
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Original Research

Article
Biliary stenting in advanced malignancy: an analysis of predictive factors for survival
Mehran Afshar, Koudeza Khanom, Yuk Ting Ma & Pankaj Punia
Pages: 475-479
Published online: 30 Sep 2022
AbstractforBiliary stenting in advanced malignancy: an analysis of predictive factors for survival | Full Text | References | PDF (733.4 KB)
  • 87 Views
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