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Cancer Management and Research Volume 14, 2022 - Issue
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Original Research

Treatment Responses, Toxicity, and Survival in Patients with Classical Hodgkin Lymphoma Aged ≥50 Years: A Single-Center Experience Over Two Decades

Simay Çokgezer1 Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
,
Tuğrul Elverdi2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
,
Ayşe Salihoğlu2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
,
Muhlis Cem Ar2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
,
Şeniz Öngören2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
,
Zafer Başlar2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, Turkey
&
Ahmet Emre Eşkazan2 Division of Hematology, Department of Internal Medicine, Istanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Istanbul, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9568-0894
ORCID Icon show all
Pages 1911-1921 | Published online: 07 Jun 2022

References

  • Vassilakopoulos TP, Asimakopoulos JV, Konstantopoulos K, Angelopoulou MK. Optimizing outcomes in relapsed/refractory Hodgkin lymphoma: a review of current and forthcoming therapeutic strategies. Ther Adv Hematol. 2020;11:2040620720902911. doi:10.1177/2040620720902911
  • Ansell SM. Hodgkin lymphoma: diagnosis and treatment. Mayo Clin Proc. 2015;90(11):1574–1583. doi:10.1016/j.mayocp.2015.07.005
  • Proctor SJ, Wilkinson J, Sieniawski M. Hodgkin lymphoma in the elderly: a clinical review of treatment and outcome, past, present and future. Crit Rev Oncol Hematol. 2009;71(3):222–232. doi:10.1016/j.critrevonc.2008.12.007
  • Sykorova A, Mocikovab H, Lukasova M, et al. Outcome of elderly patients with classical Hodgkin’s lymphoma. Leuk Res. 2020;90:106311. doi:10.1016/j.leukres.2020.106311
  • Moccia AA, Aeppli S, Güsewell S, et al. Clinical characteristics and outcome of patients over 60 years with Hodgkin lymphoma treated in Switzerland. Hematol Oncol. 2020;39:1–9.
  • National Cancer Institute. Cancer stat facts: Hodgkin lymphoma. Surveillance E, and End Results (SEER) Program; 2018.
  • Wróbel T, Biecek P, Rybka J, et al. Hodgkin lymphoma of the elderly patients: a retrospective multicenter analysis from the Polish Lymphoma Research Group. Leuk Lymphoma. 2019;60(2):341–348. doi:10.1080/10428194.2018.1482539
  • Helsing MD. Trofosfamide as a salvage treatment with low toxicity in malignant lymphoma. A Phase II study. Eur J Cancer. 1997;33(3):500–502. doi:10.1016/S0959-8049(97)89029-6
  • Salvi F, Miller MD, Grilli A, et al. A manual of guidelines to score the modified cumulative illness rating scale and its validation in acute hospitalized elderly patients. J Am Geriatr Soc. 2008;56(10):1926–1931. doi:10.1111/j.1532-5415.2008.01935.x
  • Yancik R, Wesley MN, Ries LA, et al. Comorbidity and age as predictors of risk for early mortality of male and female colon carcinoma patients: a population-based study. Cancer. 1998;82:2123–2134. doi:10.1002/(SICI)1097-0142(19980601)82:11<2123::AID-CNCR6>3.0.CO;2-W
  • Diehl V, Re D, Josting A. Hodgkin’s disease: clinical manifestation, staging, and therapy. Hematol Basic Princ Pract. 2005;2005:1347–1377.
  • Türkiye İstatistik Kurumu. Haber Bülten. 2020; 33712. [ Turkish]. Available from: https://data.tuik.gov.tr/Bulten/Index?p=Istatistiklerle-Yaslilar-2020-37227. Accessed June 1, 2022.
  • National Cancer Institute (US). Common terminology criteria for adverse events (CTCAE).v.5.0 [5x7]. Cancer Ther Eval Progr. 2017;155:90–92.
  • Engert A, Ballova V, Haverkamp H, et al. Hodgkin’s lymphoma in elderly patients: a comprehensive retrospective analysis from the German Hodgkin’s Study Group. J Clin Oncol. 2005;23(22):5052–5060. doi:10.1200/JCO.2005.11.080
  • Evens AM, Sweetenham JW, Horning SJ. Hodgkin lymphoma in older patients: an uncommon disease in need of study. Oncol. 2008;22(12):1369–1379.
  • Goyal G, Maldonado EB, Fan TJ, et al. Treatment patterns and outcomes in early-stage Hodgkin lymphoma in the elderly: a National Cancer Database Analysis. Clin Lymphoma, Myeloma Leuk. 2017;17(12):812–818. doi:10.1016/j.clml.2017.09.009
  • Carbone A, Spina M, Gloghini A, Tirelli U. Classical Hodgkin’s lymphoma arising in different host’s conditions: pathobiology parameters, therapeutic options, and outcome. Am J Hematol. 2011;86(2):170–179. doi:10.1002/ajh.21910
  • Major A, Jackson MW, Smith DE, Kamdar M, Rabinovitch R. Inferior outcomes and treatment disparities in elderly patients with classical Hodgkin lymphoma: a national cancer data base analysis. Leuk Lymphoma. 2019;60(5):1234–1243. doi:10.1080/10428194.2018.1522435
  • Eichenauer DA, Engert A, André M, et al. ESMO guidelines working group.Hodgkin’s lymphoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2018;29(Suppl4):iv19–iv29. doi:10.1093/annonc/mdy080
  • Carter J, David KA, Kritharis A, Evens AM. Current treatment options for older patients with Hodgkin lymphoma. Curr Treat Options Oncol. 2020;21(5). doi:10.1007/s11864-020-00745-9
  • Cencini E, Fabbri A, Sicuranza A, Santoni A, Bocchia M. Hodgkin lymphoma in the elderly: new perspectives and a 10-year monocenter real-life experience. Hematol Oncol. 2019;37(4):493–495. doi:10.1002/hon.2675
  • Puig N, Pintilie M, Seshadri T. High-dose chemotherapy and auto-SCT in elderly patients with Hodgkin’s lymphoma. Bone Marrow Transplant. 2011;46:1339–1344. doi:10.1038/bmt.2010.294
  • Böll B, Goergen H, Arndt N, et al. Relapsed Hodgkin lymphoma in older patients: a comprehensive analysis from the German Hodgkin Study Group. J Clin Oncol. 2013;31(35):4431–4437. doi:10.1200/JCO.2013.49.8246
  • Galli E, Cuccaro A, Maiolo E, et al. Comorbidity assessment to determine prognosis in older adult patients with classical Hodgkin lymphoma. Hematol Oncol. 2020;38:153–161. doi:10.1002/hon.2715

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