MicroRNA function and dysregulation in bone tumors: the evidence to date

References

• MirnezamiAHPickardKZhangLPrimroseJNPackhamGMicroRNAs: key players in carcinogenesis and novel therapeutic targetsEur J Surg Oncol200935433934718644693
   PubMed Web of Science ®Google Scholar
• AmbrosVBartelBBartelDPA uniform system for microRNA annotationRNA20039327727912592000
   PubMed Web of Science ®Google Scholar
• Griffiths-JonesSSainiHKvan DongenSEnrightAJmiRBase: tools for microRNA genomicsNucleic Acids Res200836Database issueD154D15817991681
   PubMed Web of Science ®Google Scholar
• LeeRCFeinbaumRLAmbrosVThe C elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Cell19937558438548252621
   PubMed Web of Science ®Google Scholar
• miRBase 20 [homepage on the Internet]ManchesterThe University of Manchester2013 Available from: http://www.mirbase.org/index.shtmlAccessed September 12, 2013
   Google Scholar
• Griffiths-JonesSThe microRNA RegistryNucleic Acids Res200432Database issueD109D11114681370
   PubMed Web of Science ®Google Scholar
• Griffiths-JonesSmiRBase: the microRNA sequence databaseMethods Mol Biol2006342129138
   PubMedGoogle Scholar
• Griffiths-JonesSmiRBase: microRNA sequences and annotationCurr Protoc Bioinformatics2010Chapter 12Unit 12.9.1Unit 12.910
   Google Scholar
• Griffiths-JonesSGrocockRJvan DongenSBatemanAEnrightAJmiRBase: microRNA sequences, targets and gene nomenclatureNucleic Acids Res200634Database issueD140D14416381832
   PubMed Web of Science ®Google Scholar
• KozomaraAGriffiths-JonesSmiRBase: integrating microRNA annotation and deep-sequencing dataNucleic Acids Res201139Database issueD152D15721037258
   PubMed Web of Science ®Google Scholar
• HeLHannonGJMicroRNAs: small RNAs with a big role in gene regulationNat Rev Genet20045752253115211354
   PubMed Web of Science ®Google Scholar
• Valencia-SanchezMALiuJHannonGJParkerRControl of translation and mRNA degradation by miRNAs and siRNAsGenes Dev200620551552416510870
   PubMed Web of Science ®Google Scholar
• BartelDPMicroRNAs: genomics, biogenesis, mechanism, and functionCell2004116228129714744438
   PubMed Web of Science ®Google Scholar
• WinterJJungSKellerSGregoryRIDiederichsSMany roads to maturity: microRNA biogenesis pathways and their regulationNat Cell Biol200911322823419255566
   PubMed Web of Science ®Google Scholar
• HammondSMCaudyAAHannonGJPost-transcriptional gene silencing by double-stranded RNANat Rev Genet20012211011911253050
   PubMed Web of Science ®Google Scholar
• LiSFuHWangYMicroRNA-101 regulates expression of the v-fos FBJ murine osteosarcoma viral oncogene homolog (FOS) oncogene in human hepatocellular carcinomaHepatology20094941194120219133651
   PubMed Web of Science ®Google Scholar
• SlabyOSvobodaMMichalekJVyzulaRMicroRNAs in colorectal cancer: translation of molecular biology into clinical applicationMol Cancer2009810219912656
   PubMed Web of Science ®Google Scholar
• WijnhovenBPMichaelMZWatsonDIMicroRNAs and cancerBr J Surg2007941233017205498
   PubMed Web of Science ®Google Scholar
• FaberCKirchnerTHlubekFThe impact of microRNAs on colorectal cancerVirchows Arch2009454435936719288129
   PubMed Web of Science ®Google Scholar
• RossiSKopetzSDavuluriRHamiltonSRCalinGAMicroRNAs, ultraconserved genes and colorectal cancersInt J Biochem Cell Biol201042812911297
   PubMed Web of Science ®Google Scholar
• CumminsJMVelculescuVEImplications of micro-RNA profiling for cancer diagnosisOncogene200625466220622717028602
   PubMed Web of Science ®Google Scholar
• BandresEAgirreXBitarteNEpigenetic regulation of microRNA expression in colorectal cancerInt J Cancer2009125112737274319521961
   PubMed Web of Science ®Google Scholar
• LiuXChenXYuXRegulation of microRNAs by epigenetics and their interplay involved in cancerJ Exp Clin Cancer Res20133219624261995
   PubMed Web of Science ®Google Scholar
• XiYShalgiRFodstadOPilpelYJuJDifferentially regulated micro-RNAs and actively translated messenger RNA transcripts by tumor suppressor p53 in colon cancerClin Cancer Res2006127 Pt 12014202416609010
   PubMed Web of Science ®Google Scholar
• MengWMcElroyJPVoliniaSComparison of microRNA deep sequencing of matched formalin-fixed paraffin-embedded and fresh frozen cancer tissuesPLoS One201385e6439323696889
   PubMed Web of Science ®Google Scholar
• MitchellPSParkinRKKrohEMCirculating microRNAs as stable blood-based markers for cancer detectionProc Natl Acad Sci U S A200810530105131051818663219
   PubMed Web of Science ®Google Scholar
• WarkAWLeeHJCornRMMultiplexed detection methods for profiling microRNA expression in biological samplesAngew Chem Int Ed Engl200847464465217994653
   PubMed Web of Science ®Google Scholar
• KloostermanWPWienholdsEde BruijnEKauppinenSPlasterkRHIn situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probesNat Methods200631272916369549
   PubMed Web of Science ®Google Scholar
• CastoldiMSchmidtSBenesVHentzeMWMuckenthalerMUmiChip: an array-based method for microRNA expression profiling using locked nucleic acid capture probesNat Protoc20083232132918274534
   PubMed Web of Science ®Google Scholar
• CastoldiMSchmidtSBenesVA sensitive array for microRNA expression profiling (miChip) based on locked nucleic acids (LNA)RNA200612591392016540696
   PubMed Web of Science ®Google Scholar
• LuJGetzGMiskaEAMicroRNA expression profiles classify human cancersNature2005435704383483815944708
   PubMed Web of Science ®Google Scholar
• KheirelseidEAChangKHNewellJKerinMJMillerNIdentification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancerBMC Mol Biol2010111220122155
   PubMed Web of Science ®Google Scholar
• ChangKHMestdaghPVandesompeleJKerinMJMillerNMicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancerBMC Cancer20101017320429937
   PubMed Web of Science ®Google Scholar
• MirnezamiAHPickardKZhangLPrimroseJNPackhamGMicroRNAs: key players in carcinogenesis and novel therapeutic targetsEur J Surg Oncol200935433934718644693
   PubMed Web of Science ®Google Scholar
• KobayashiEHornicekFJDuanZMicroRNA Involvement in OsteosarcomaSarcoma20122012359739
   PubMedGoogle Scholar
• OttavianiGJaffeNThe epidemiology of osteosarcomaCancer Treat Res200915231320213383
   PubMedGoogle Scholar
• TangNSongWXLuoJHaydonRCHeTCOsteosarcoma development and stem cell differentiationClin Orthop Relat Res200846692114213018563507
   PubMed Web of Science ®Google Scholar
• BielackSSKempf-BielackBDellingGPrognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocolsJ Clin Oncol200220377679011821461
   PubMed Web of Science ®Google Scholar
• GellerDSGorlickROsteosarcoma: a review of diagnosis, management, and treatment strategiesClin Adv Hematol Oncol201081070571821317869
   PubMedGoogle Scholar
• HeCXiongJXuXFunctional elucidation of MiR-34 in osteosarcoma cells and primary tumor samplesBiochem Biophys Res Commun20093881354019632201
   PubMed Web of Science ®Google Scholar
• WangZLiYBanerjeeSSarkarFHEmerging role of Notch in stem cells and cancerCancer Lett2009279181219022563
   PubMed Web of Science ®Google Scholar
• WangZLiYKongDAhmadABanerjeeSSarkarFHCross-talk between miRNA and Notch signaling pathways in tumor development and progressionCancer Lett2010292214114820022691
   PubMed Web of Science ®Google Scholar
• BaeYYangTZengHCmiRNA-34c regulates Notch signaling during bone developmentHum Mol Genet201221132991300022498974
   PubMed Web of Science ®Google Scholar
• LiJLiuWZhaoKDiallyl trisulfide reverses drug resistance and lowers the ratio of CD133+ cells in conjunction with methotrexate in a human osteosarcoma drug-resistant cell sublineMol Med Rep20092224525221475820
   PubMed Web of Science ®Google Scholar
• LiYZhangJZhangLSiMYinHLiJDiallyl trisulfide inhibits proliferation, invasion and angiogenesis of osteosarcoma cells by switching on suppressor microRNAs and inactivating of Notch-1 signalingCarcinogenesis20133471601161023430952
   PubMed Web of Science ®Google Scholar
• HeLHeXLimLPA microRNA component of the p53 tumour suppressor networkNature200744771481130113417554337
   PubMed Web of Science ®Google Scholar
• SongLYangJDuanPMicroRNA-24 inhibits osteosarcoma cell proliferation both in vitro and in vivo by targeting LPAATβArch Biochem Biophys2013535212813523578572
   PubMed Web of Science ®Google Scholar
• AnnunziataMGranataRGhigoEThe IGF systemActa Diabetol20114811921042815
   PubMed Web of Science ®Google Scholar
• ChenLWangQWangGDmiR-16 inhibits cell proliferation by targeting IGF1R and the Raf1-MEK1/2-ERK1/2 pathway in osteosarcomaFEBS Lett201358791366137223507142
   PubMed Web of Science ®Google Scholar
• MaireGMartinJWYoshimotoMChilton-MacNeillSZielenskaMSquireJAAnalysis of miRNA-gene expression-genomic profiles reveals complex mechanisms of microRNA deregulation in osteosarcomaCancer Genet2011204313814621504713
   PubMed Web of Science ®Google Scholar
• ThayanithyVSarverALKarthaRVPerturbation of 14q32 miRNAs-cMYC gene network in osteosarcomaBone201250117118122037351
   PubMed Web of Science ®Google Scholar
• SarverALThayanithyVScottMCMicroRNAs at the human 14q32 locus have prognostic significance in osteosarcomaOrphanet J Rare Dis20138723311495
   PubMed Web of Science ®Google Scholar
• LafleurEAKoshkinaNVStewartJIncreased Fas expression reduces the metastatic potential of human osteosarcoma cellsClin Cancer Res200410238114811915585647
   PubMed Web of Science ®Google Scholar
• WorthLLLafleurEAJiaSFKleinermanESFas expression inversely correlates with metastatic potential in osteosarcoma cellsOncol Rep20029482382712066216
   PubMed Web of Science ®Google Scholar
• HuangGNishimotoKZhouZHughesDKleinermanESmiR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expressionCancer Res201272490891622186140
   PubMed Web of Science ®Google Scholar
• OsakiMTakeshitaFSugimotoYMicroRNA-143 regulates human osteosarcoma metastasis by regulating matrix metalloprotease-13 expressionMol Ther20111961123113021427707
   PubMed Web of Science ®Google Scholar
• JonesKBSalahZDel MareSmiRNA signatures associate with pathogenesis and progression of osteosarcomaCancer Res20127271865187722350417
   PubMed Web of Science ®Google Scholar
• MontaniniLLasagnaLBariliVMicroRNA cloning and sequencing in osteosarcoma cell lines: differential role of miR-93Cell Oncol (Dordr)2012351294121959981
   PubMed Web of Science ®Google Scholar
• ZhuJFengYKeZDown-regulation of miR-183 promotes migration and invasion of osteosarcoma by targeting EzrinAm J Pathol201218062440245122525461
   PubMed Web of Science ®Google Scholar
• ZhaoHGuoMZhaoGmiR-183 inhibits the metastasis of osteosarcoma via downregulation of the expression of Ezrin in F5M2 cellsInt J Mol Med20123051013102022922800
   PubMed Web of Science ®Google Scholar
• WangYZhaoWFuQmiR-335 suppresses migration and invasion by targeting ROCK1 in osteosarcoma cellsMol Cell Biochem20133841–210511123975506
   PubMed Web of Science ®Google Scholar
• ZhouXWeiMWangWMicroRNA-340 suppresses osteosarcoma tumor growth and metastasis by directly targeting ROCK1Biochem Biophys Res Commun2013437465365823872151
   PubMed Web of Science ®Google Scholar
• GougeletAPissalouxDBesseAMicro-RNA profiles in osteosarcoma as a predictive tool for ifosfamide responseInt J Cancer2011129368069020949564
   PubMed Web of Science ®Google Scholar
• ZhaoGCaiCYangTMicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcomaPLoS One201381e5390623372675
   PubMed Web of Science ®Google Scholar
• CaiHLinLCaiHTangMWangZPrognostic evaluation of microRNA-210 expression in pediatric osteosarcomaMed Oncol201330249923430441
   PubMed Web of Science ®Google Scholar
• SongBWangYXiYMechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cellsOncogene200928464065407419734943
   PubMed Web of Science ®Google Scholar
• BaoYPYiYPengLLRoles of microRNA-206 in osteosarcoma pathogenesis and progressionAsian Pac J Cancer Prev20131463751375523886177
   PubMedGoogle Scholar
• YangJGaoTTangJCaiHLinLFuSLoss of microRNA-132 predicts poor prognosis in patients with primary osteosarcomaMol Cell Biochem20133811–291523801049
   PubMed Web of Science ®Google Scholar
• TangMLinLCaiHTangJZhouZMicroRNA-145 downregulation associates with advanced tumor progression and poor prognosis in patients suffering osteosarcomaOnco Targets Ther2013683383823874105
   PubMed Web of Science ®Google Scholar
• WangZCaiHLinLTangMCaiHUpregulated expression of microRNA-214 is linked to tumor progression and adverse prognosis in pediatric osteosarcomaPediatr Blood Cancer2013
   Web of Science ®Google Scholar
• KellyADHaibe-KainsBJanewayKAMicroRNA paraffin-based studies in osteosarcoma reveal reproducible independent prognostic profiles at 14q32Genome Med201351223339462
   PubMed Web of Science ®Google Scholar
• SchwabJHSpringfieldDSRaskinKAMankinHJHornicekFJWhat’s new in primary bone tumorsJ Bone Joint Surg Am201294201913191923079883
   PubMed Web of Science ®Google Scholar
• RiggiNStamenkovicIThe Biology of Ewing sarcomaCancer Lett2007254111017250957
   PubMed Web of Science ®Google Scholar
• KovarHDownstream EWS/FLI1 – upstream Ewing’s sarcomaGenome Med201021820156317
   PubMed Web of Science ®Google Scholar
• KinseyMSmithRIyerAKMcCabeERLessnickSLEWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing’s sarcomaCancer Res200969239047905519920188
   PubMed Web of Science ®Google Scholar
• BanJJugGMestdaghPHsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing’s sarcomaOncogene201130182173218021217773
   PubMed Web of Science ®Google Scholar
• De VitoCRiggiNSuvàMLLet-7a is a direct EWS-FLI-1 target implicated in Ewing’s sarcoma developmentPLoS One201168e2359221853155
   PubMed Web of Science ®Google Scholar
• RobinTPSmithAMcKinseyEReavesLJedlickaPFordHLEWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistanceMol Cancer Res20121081098110822723308
   PubMed Web of Science ®Google Scholar
• NakataniFFerracinMManaraMCmiR-34a predicts survival of Ewing’s sarcoma patients and directly influences cell chemo-sensitivity and malignancyJ Pathol2012226579680521960059
   PubMed Web of Science ®Google Scholar
• DavidEBlanchardFHeymannMFThe Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic TargetsSarcoma2011201193245121647363
   PubMedGoogle Scholar
• YoshitakaTKawaiAMiyakiSAnalysis of microRNAs expressions in chondrosarcomaJ Orthop Res201331121992199823940002
   PubMed Web of Science ®Google Scholar
• GaloianKAGuettoucheTIssacBQureshiATempleHTRegulation of onco and tumor suppressor MiRNAs by mTORC1 inhibitor PRP-1 in human chondrosarcomaTumour Biol2013
   Google Scholar
• LiangWLiXLiYGallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cellsInt J Oncol2014441919824173143
   PubMed Web of Science ®Google Scholar
• SchmaleGAConradEURaskindWHThe natural history of hereditary multiple exostosesJ Bone Joint Surg Am19947679869928027127
   PubMed Web of Science ®Google Scholar
• ZuntiniMSalvatoreMPedriniEMicroRNA profiling of multiple osteochondromas: identification of disease-specific and normal cartilage signaturesClin Genet201078650751620662852
   PubMed Web of Science ®Google Scholar
• RaskinKASchwabJHMankinHJSpringfieldDSHornicekFJGiant cell tumor of boneJ Am Acad Orthop Surg201321211812623378375
   PubMed Web of Science ®Google Scholar
• MosakhaniNPazzagliaLBenassiMSMicroRNA expression profiles in metastatic and non-metastatic giant cell tumor of boneHistol Histopathol201328567167823172052
   PubMed Web of Science ®Google Scholar
• IbrahimTMercataliLAmadoriDBone and cancer: the osteoncologyClin Cases Miner Bone Metab201310212112324133529
   PubMedGoogle Scholar
• MaLTeruya-FeldsteinJWeinbergRATumour invasion and metastasis initiated by microRNA-10b in breast cancerNature2007449716368268817898713
   PubMed Web of Science ®Google Scholar
• LujambioACalinGAVillanuevaAA microRNA DNA methylation signature for human cancer metastasisProc Natl Acad Sci U S A200810536135561356118768788
   PubMed Web of Science ®Google Scholar
• HuangLDaiTLinXMicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cellsBiochem Biophys Res Commun2012425212713322809510
   PubMed Web of Science ®Google Scholar
• GongMMaJGuillemetteRmiR-335 Inhibits Small Cell Lung Cancer Bone Metastases via IGF-1R and RANKL PathwaysMol Cancer Res Epub20131210
   Google Scholar
• KuoPLLiaoSHHungJYHuangMSHsuYLMicroRNA-33a functions as a bone metastasis suppressor in lung cancer by targeting parathyroid hormone related proteinBiochim Biophys Acta2013183063756376623458685
   PubMed Web of Science ®Google Scholar
• GuoWRenDChenXHEF1 promotes epithelial mesenchymal transition and bone invasion in prostate cancer under the regulation of microRNA-145J Cell Biochem201311471606161523355420
   PubMed Web of Science ®Google Scholar
• PengXGuoWLiuTIdentification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMTPLoS One201165e2034121647377
   PubMed Web of Science ®Google Scholar
• SainiSMajidSYamamuraSRegulatory Role of mir-203 in Prostate Cancer Progression and MetastasisClin Cancer Res201117165287529821159887
   PubMed Web of Science ®Google Scholar
• ViticchièGLenaAMLatinaAMiR-203 controls proliferation, migration and invasive potential of prostate cancer cell linesCell Cycle20111071121113121368580
   PubMed Web of Science ®Google Scholar
• HeneghanHMMillerNLoweryAJSweeneyKJNewellJKerinMJCirculating microRNAs as novel minimally invasive biomarkers for breast cancerAnn Surg2010251349950520134314
   PubMed Web of Science ®Google Scholar
• NugentMMillerNKerinMJCirculating miR-34a levels are reduced in colorectal cancerJ Surg Oncol2012106894795222648208
   PubMed Web of Science ®Google Scholar
• ChenXBaYMaLCharacterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseasesCell Res20081810997100618766170
   PubMed Web of Science ®Google Scholar
• OuyangLLiuPYangSYeSXuWLiuXA three-plasma miRNA signature serves as novel biomarkers for osteosarcomaMed Oncol201330134023269581
   PubMed Web of Science ®Google Scholar
• OsadaHTakahashiTMicroRNAs in biological processes and carcinogenesisCarcinogenesis200728121217028302
   PubMed Web of Science ®Google Scholar
• ZhangYHuHSongLCaiLWeiRJinWEpirubicin-mediated expression of miR-302b is involved in osteosarcoma apoptosis and cell cycle regulationToxicol Lett201322211923845851
   PubMed Web of Science ®Google Scholar
• LanfordREHildebrandt-EriksenESPetriATherapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infectionScience2010327596219820119965718
   PubMed Web of Science ®Google Scholar
• IdogawaMSasakiYSuzukiHA single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cellsClin Cancer Res200915113725373219458054
   PubMed Web of Science ®Google Scholar
• WigginsJFRuffinoLKelnarKDevelopment of a lung cancer therapeutic based on the tumor suppressor microRNA-34Cancer Res201070145923593020570894
   PubMed Web of Science ®Google Scholar
• MaLReinhardtFPanETherapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor modelNat Biotechnol201028434134720351690
   PubMed Web of Science ®Google Scholar
• ZiyanWShuhuaYXiufangWXiaoyunLMicroRNA-21 is involved in osteosarcoma cell invasion and migrationMed Oncol20112841469147420480266
   PubMed Web of Science ®Google Scholar
• LullaRRCostaFFBischofJMIdentification of Differentially Expressed MicroRNAs in OsteosarcomaSarcoma2011201173269021789031
   PubMedGoogle Scholar
• ZhangWQianJXYiHLThe microRNA-29 plays a central role in osteosarcoma pathogenesis and progressionMol Biol (Mosk)201246462262723113351
   PubMed Web of Science ®Google Scholar
• BaglìoSRDevescoviVGranchiDBaldiniNMicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31Gene2013527132133123827457
   PubMed Web of Science ®Google Scholar
• YanKGaoJYangTMicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivoPLoS One201273e3377822457788
   PubMed Web of Science ®Google Scholar
• WonKYKimYWKimHSLeeSKJungWWParkYKMicroRNA-199b-5p is involved in the Notch signaling pathway in osteosarcomaHum Pathol20134481648165523574781
   PubMed Web of Science ®Google Scholar
• van der DeenMTaipaleenmäkiHZhangYMicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcomaJ Biol Chem201328829213072131923720736
   PubMed Web of Science ®Google Scholar
• LiuLHLiHLiJPmiR-125b suppresses the proliferation and migration of osteosarcoma cells through down-regulation of STAT3Biochem Biophys Res Commun20114161–2313822093834
   PubMed Web of Science ®Google Scholar
• JiFZhangHWangYMicroRNA-133a, downregulated in osteosarcoma, suppresses proliferation and promotes apoptosis by targeting Bcl-xL and Mcl-1Bone201356122022623756231
   PubMed Web of Science ®Google Scholar
• DuanZChoyEHarmonDMicroRNA-199a-3p is downregulated in human osteosarcoma and regulates cell proliferation and migrationMol Cancer Ther20111081337134521666078
   PubMed Web of Science ®Google Scholar
• LongXHMaoJHPengAFZhouYHuangSHLiuZLTumor suppressive microRNA-424 inhibits osteosarcoma cell migration and invasion via targeting fatty acid synthaseExp Ther Med2013541048105223599729
   PubMed Web of Science ®Google Scholar
• FranzettiGALaud-DuvalKBellangerDSternMHSastre-GarauXDelattreOMiR-30a-5p connects EWS-FLI1 and CD99, two major therapeutic targets in Ewing tumorOncogene201332333915392122986530
   PubMed Web of Science ®Google Scholar
• RiggiNSuvàMLDe VitoCEWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cellsGenes Dev201024991693220382729
   PubMed Web of Science ®Google Scholar