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Original Research

Dysregulation of microRNA-214 and PTEN contributes to the pathogenesis of hypoxic pulmonary hypertension

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Pages 1781-1791 | Published online: 19 Jun 2017

References

  • RabinovitchMCellular and molecular pathobiology of pulmonary hypertension conference summaryChest20051286 suppl642S646S16373886
  • AgarwalRGomberg-MaitlandMCurrent therapeutics and practical management strategies for pulmonary arterial hypertensionAm Heart J2011162220121321835279
  • HuangJKontosCDInhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTENArterioscler Thromb Vasc Biol200222574575112006385
  • NemenoffRASimpsonPAFurgesonSBTargeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alphaCirc Res200810291036104518340011
  • NisbetREBlandJMKleinhenzDJRosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse modelAm J Respir Cell Mol Biol201042448249019520921
  • RubinLJCellular and molecular mechanisms responsible for the pathogenesis of primary pulmonary hypertensionPediatr Pulmonol Suppl19991819419710093141
  • PietraGGCapronFStewartSPathologic assessment of vasculopathies in pulmonary hypertensionJ Am Coll Cardiol20044312 suppl S25S32S15194175
  • HumbertMMorrellNWArcherSLCellular and molecular pathobiology of pulmonary arterial hypertensionJ Am Coll Cardiol20044312 suppl S13S24S15194174
  • DorfmüllerPPerrosFBalabanianKHumbertMInflammation in pulmonary arterial hypertensionEur Respir J200322235836312952274
  • Valencia-SanchezMALiuJHannonGJParkerRControl of translation and mRNA degradation by miRNAs and siRNAsGenes Dev200620551552416510870
  • HobertOGene regulation by transcription factors and microRNAsScience200831958711785178618369135
  • ChanSYLoscalzoJMicroRNA-210: a unique and pleiotropic hypoxamirCell Cycle2010961072108320237418
  • HaleAEWhiteKChanSYHypoxamirs in pulmonary hypertension: breathing new life into pulmonary vascular researchCardiovasc Diagn Ther20122320021223745175
  • LujambioACalinGAVillanuevaAA microRNA DNA methylation signature for human cancer metastasisProc Natl Acad Sci U S A200810536135561356118768788
  • AmbsSPrueittRLYiMGenomic profiling of microRNA and messenger RNA reveals deregulated microRNA expression in prostate cancerCancer Res200868156162617018676839
  • YangHKongWHeLMicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTENCancer Res200868242543318199536
  • ChengYJiRYueJMicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy?Am J Pathol200717061831184017525252
  • IzzottiACalinGAArrigoPSteeleVECroceCMDe FloraSDownregulation of microRNA expression in the lungs of rats exposed to cigarette smokeFASEB J200923380681218952709
  • LuMZhangQDengMAn analysis of human microRNA and disease associationsPLoS One2008310e342018923704
  • TuccariGBarresiGLactoferrin in human tumours: immunohistochemical investigations during more than 25 yearsBiometals201124577578421472415
  • KanaanZRaiSNEichenbergerMRDifferential microRNA expression tracks neoplastic progression in inflammatory bowel disease-associated colorectal cancerHum Mutat201233355156022241525
  • VergoulisTVlachosISAlexiouPTarBase 6.0: capturing the exponential growth of miRNA targets with experimental supportNucleic Acids Res201240Database issueD222D22922135297
  • PennaEOrsoFCiminoDmicroRNA-214 contributes to melanoma tumour progression through suppression of TFAP2CEMBO J201130101990200721468029
  • YangZChenSLuanXMicroRNA-214 is aberrantly expressed in cervical cancers and inhibits the growth of HeLa cellsIUBMB Life200961111075108219859982
  • ZhouSLiMZengDA single nucleotide polymorphism in 3′ untranslated region of epithelial growth factor receptor confers risk for pulmonary hypertension in chronic obstructive pulmonary diseaseCell Physiol Biochem201536116617825925667
  • PaulinRCourboulinABarrierMBonnetSFrom oncoproteins/tumor suppressors to microRNAs, the newest therapeutic targets for pulmonary arterial hypertensionJ Mol Med (Berl)201189111089110121761156
  • BoucheratOPotusFBonnetSmicroRNA and pulmonary hypertensionAdv Exp Med Biol201588823725226663186
  • MoonSKKimHMKimCHPTEN induces G1 cell cycle arrest and inhibits MMP-9 expression via the regulation of NF-kappaB and AP-1 in vascular smooth muscle cellsArch Biochem Biophys2004421226727614984207
  • TamguneyTStokoeDNew insights into PTENJ Cell Sci2007120pt 234071407918032782
  • Van de SandeTDe SchrijverEHeynsWVerhoevenGSwinnenJVRole of the phosphatidylinositol 3′-kinase/PTEN/Akt kinase pathway in the overexpression of fatty acid synthase in LNCaP prostate cancer cellsCancer Res200262364264611830512
  • OuditGYPenningerJMCardiac regulation by phosphoinositide 3-kinases and PTENCardiovasc Res200982225026019147653
  • OuditGYSunHKerfantBGCrackowerMAPenningerJMBackxPHThe role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and diseaseJ Mol Cell Cardiol200437244947115276015
  • NoureddineHGary-BoboGAlifanoMPulmonary artery smooth muscle cell senescence is a pathogenic mechanism for pulmonary hypertension in chronic lung diseaseCirc Res2011109554355321719760
  • DattaSRDudekHTaoXAkt phosphorylation of BAD couples survival signals to the cell-intrinsic death machineryCell19979122312419346240
  • VoelkelNFTuderRMHypoxia-induced pulmonary vascular remodeling: a model for what human disease?J Clin Invest2000106673373810995781