Inhaled corticosteroid normalizes some but not all airway vascular remodeling in COPD

References

• BarnesPJShapiroSDPauwelsRAChronic obstructive pulmonary disease: molecular and cellular mechanismsEur Respir J200322467268814582923
   PubMed Web of Science ®Google Scholar
• SohalSSReidDSoltaniAReticular basement membrane fragmentation and potential epithelial mesenchymal transition is exaggerated in the airways of smokers with chronic obstructive pulmonary diseaseRespirology201015693093820630030
   PubMed Web of Science ®Google Scholar
• SohalSReidDSoltaniAEvaluation of epithelial mesenchymal transition in patients with chronic obstructive pulmonary diseaseRespir Res201112113021970519
   PubMedGoogle Scholar
• SoltaniAReidDSohalSBasement membrane and vascular remodelling in smokers and chronic obstructive pulmonary disease: a cross-sectional studyRespir Res201011110520670454
   PubMed Web of Science ®Google Scholar
• SoltaniAMullerHKSohalSSDistinctive characteristics of bronchial reticular basement membrane and vessel remodelling in chronic obstructive pulmonary disease (COPD) and in asthma: they are not the same diseaseHistopathology201260696497022320998
   PubMed Web of Science ®Google Scholar
• SoltaniASohalSSReidDVessel-associated transforming growth factor-beta1 (TGF-β1) is increased in the bronchial reticular basement membrane in COPD and normal smokersPLoS One201276e3973622768115
   PubMed Web of Science ®Google Scholar
• SoltaniAWood-BakerRSohalSSMullerHKReidDWaltersEHReticular basement membrane vessels are increased in COPD bronchial mucosa by both factor VIII and collagen IV immunostaining and are hyperpermeableJ Allergy (Cairo)201295838322500190
   PubMedGoogle Scholar
• HiroshimaKIyodaAShibuyaKEvidence of neoangiogenesis and an increase in the number of proliferating cells within the bronchial epithelium of smokersCancer20029571539154512237923
   PubMed Web of Science ®Google Scholar
• SohalSSSoltaniAReidDA randomized controlled trial of inhaled corticosteroids (ICS) on markers of epithelial-mesenchymal transition (EMT) in large airway samples in COPD: an exploratory proof of concept studyInt J Chron Obstruct Pulmon Dis2014953354224920891
   PubMed Web of Science ®Google Scholar
• MagnussenHDisseBRodriguez-RoisinRWithdrawal of inhaled glucocorticoids and exacerbations of COPDN Engl J Med2014371141285129425196117
   PubMed Web of Science ®Google Scholar
• YangIAFongKMSimEHBlackPNLassersonTJInhaled corticosteroids for stable chronic obstructive pulmonary diseaseCochrane Database Syst Rev20127CD00299122786484
   PubMed Web of Science ®Google Scholar
• ReidDWWenYJohnsDPWilliamsTJWardCWaltersEHBronchodilator reversibility, airway eosinophilia and anti-inflammatory effects of inhaled fluticasone in COPD are not relatedRespirology200813679980918811878
   PubMed Web of Science ®Google Scholar
• ZaniniAChettaASaettaMBronchial vascular remodelling in patients with COPD and its relationship with inhaled steroid treatmentThorax200964121019102419736178
   PubMed Web of Science ®Google Scholar
• LapperreTSSnoeck-StrobandJBGosmanMMEffect of fluticasone with and without salmeterol on pulmonary outcomes in chronic obstructive pulmonary disease: a randomized trialAnn Intern Med2009151851752719841453
   PubMed Web of Science ®Google Scholar
• HoonhorstSJten HackenNHVonkJMSteroid resistance in COPD? Overlap and differential anti-inflammatory effects in smokers and ex-smokersPLoS One201492e8744324505290
   PubMed Web of Science ®Google Scholar
• KunzLIStrebusJBudulacSEInhaled steroids modulate extracellular matrix composition in bronchial biopsies of COPD patients: a randomized, controlled trialPLoS One201385e6343023667615
   PubMed Web of Science ®Google Scholar
• ParimonTChienJWBrysonCLMcDonellMBUdrisEMAuDHInhaled corticosteroids and risk of lung cancer among patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2007175771271917185647
   PubMed Web of Science ®Google Scholar
• LamSleRicheJCMcWilliamsAA randomized phase IIb trial of pulmicort turbuhaler (budesonide) in people with dysplasia of the bronchial epitheliumClin Cancer Res200410196502651115475437
   PubMed Web of Science ®Google Scholar
• VeronesiGSzaboEDeCensiARandomized phase ii trial of inhaled budesonide versus placebo in high-risk individuals with CT screen–detected lung nodulesCancer Prev Res (Phila)201141344221163939
   PubMed Web of Science ®Google Scholar
• KiriVAFabbriLMDavisKJSorianoJBInhaled corticosteroids and risk of lung cancer among COPD patients who quit smokingRespir Med20091031859018793832
   PubMed Web of Science ®Google Scholar
• SoltaniASohalSSReidDWAirway angiogenesis and basement membrane remodeling in smokers and chronic obstructive pulmonary disease: cross-sectional and longitudinal studies [Abstract]Am J Respir Crit Care Med2010181A3874
   Web of Science ®Google Scholar
• FeltisBNWignarajahDReidDWWardCHardingRWaltersEHEffects of inhaled fluticasone on angiogenesis and vascular endothelial growth factor in asthmaThorax200762431431917105777
   PubMed Web of Science ®Google Scholar
• SohalSSReidDSoltaniAChanges in airway histone deacetylase2 in smokers and COPD with inhaled corticosteroids: a randomized controlled trialPLoS One201385e6483323717666
   PubMed Web of Science ®Google Scholar
• AnderssonCKMoriMBjermerLLöfdahlCGErjefältJSAlterations in lung mast cell populations in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2010181320621719926870
   PubMed Web of Science ®Google Scholar
• MillerMRHankinsonJBrusascoVStandardisation of spirometryEur Respir J200526231933816055882
   PubMed Web of Science ®Google Scholar
• SoltaniAEweYPLimZSMast cells in COPD airways: relationship to bronchodilator responsiveness and angiogenesisEur Respir J20123961361136722034650
   PubMed Web of Science ®Google Scholar
• SohalSSReidDWSoltaniAFluticasone propionate attenuates epithelial mesenchymal transition (EMT) in COPDRespirology201217Suppl 125
   Google Scholar
• PostmaDSTimensWRemodeling in asthma and chronic obstructive pulmonary diseaseProc Am Thorac Soc20063543443916799088
   PubMedGoogle Scholar
• RichmondIBoothHWardCWaltersEHIntrasubject variability in airway inflammation in biopsies in mild to moderate stable asthmaAm J Respir Crit Care Med199615338999038630570
   PubMed Web of Science ®Google Scholar
• FeltisBNWignarajahDZhengLIncreased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthmaAm J Respir Crit Care Med2006173111201120716528018
   PubMed Web of Science ®Google Scholar
• VerhammeFMBrackeKRJoosGFBrusselleGGTGF-beta super-family in obstructive lung diseases: more suspects than TGF-beta aloneAm J Respir Cell Mol Biol201552665366225396302
   PubMed Web of Science ®Google Scholar
• BurgessJKBoustanySMoirLMReduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation, and hyper-responsivenessAm J Respir Crit Care Med2010181210611519875687
   PubMed Web of Science ®Google Scholar
• JacksonJRSeedMPKircherCHWilloughbyDAWinklerJDThe codependence of angiogenesis and chronic inflammationFASEB J19971164574659194526
   PubMed Web of Science ®Google Scholar
• KnoxAJStocksJSutcliffeAAngiogenesis and vascular endothelial growth factor in COPDThorax2005602888915681489
   PubMed Web of Science ®Google Scholar
• HoggJCTimensWThe pathology of chronic obstructive pulmonary diseaseAnnu Rev Pathol2009443545918954287
   PubMed Web of Science ®Google Scholar