Effectiveness using higher inhaled corticosteroid dosage in patients with COPD by different blood eosinophilic counts

References

• FergusonGTAnzuetoAFeiREmmettAKnobilKKalbergCEffect of fluticasone propionate/salmeterol (250/25 microg) or salmeterol (50 microg) on COPD exacerbationRespir Med200810281099110818614347
   PubMed Web of Science ®Google Scholar
• DransfieldMTBourbeauJJonesPWOnce-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbation of COPD: two replicate double-blind, parallel-group, randomized controlled trialLancet Respir Med20131321022324429127
   PubMed Web of Science ®Google Scholar
• SzafranskiWWCukierARamirezAEfficacy and safety of budesonide/formoterol in the management of chronic obstructive pulmonary diseaseEur Respir J2003211748112570112
   PubMed Web of Science ®Google Scholar
• SharafkhanehASouthardJGGoldmanMUryniakTMartinUJEffect of budesonide/formoterol pMDI on COPD exacerbation: a double-blind, randomized studyRespir Med2012106225726822033040
   PubMed Web of Science ®Google Scholar
• AgarwaiRAggarwaiANGuptaDJindalSKInhaled corticosteroids vs placebo for preventing COPD exacerbations: a systemic review and metaregression of randomized controlled trialsChest2010137231832519783669
   PubMed Web of Science ®Google Scholar
• SuissaSNumber needed to treat in COPD: exacerbations versus pneumoniasThorax201368954054323125170
   PubMed Web of Science ®Google Scholar
• SahaSBrightlingCEEosinophilic airway inflammation in COPDInt J Chron Obstruct Pulmon Dis200611394718046901
   PubMedGoogle Scholar
• BrightlingCEClinical applications of induced sputumChest200612951344134816685028
   PubMed Web of Science ®Google Scholar
• SinghDKolsumUBringtlingCELocantoreNAgustiATsl-SingerRECLIPSE invertigatorsEosinophilic inflammation in COPD: prevalence and clinical characteristicsEur Respir J20144461697170025323230
   PubMed Web of Science ®Google Scholar
• BafadhelMMckennaSTerrySAcute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkersAm J Respir Crit Care Med2011184666267121680942
   PubMed Web of Science ®Google Scholar
• McDonaldVMHigginsIWoodLGGibsonPGMultidimensional assessment and tailored interventions for COPD: respiratory utopia or common sense?Thorax201368769169423503624
   PubMed Web of Science ®Google Scholar
• LeighRPizzichiniMMMorrisMMMaltaisFHargreaveFEPizzichiniEStable COPD: predicting benefits from high-dose inhaled corticosteroid treatmentEur Respir J200627596497116446316
   PubMed Web of Science ®Google Scholar
• BrightlingCEMonteiroWWardRSputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trialLancet200035592401480148510801167
   PubMed Web of Science ®Google Scholar
• BrightlingCEMckennaSHargadonBSputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary diseaseThorax200560319319815741434
   PubMed Web of Science ®Google Scholar
• PizzichiniEPizzichiniMMGibsonPSputum eosinophilia predicts benefit from prednisolone in smokers with chronic obstructive bronchitisAm J Respir Crit Care Med19981585 Pt 1151115179817701
   PubMed Web of Science ®Google Scholar
• PavordIDBafadhelMExhaled nitric oxide and blood eosinophilia: independent markers of preventable riskJ Allergy Clin Immunol2013132482882924001802
   PubMed Web of Science ®Google Scholar
• BainesKJPavordIDGibsonPGThe role of biomarkers in the management of airway diseaseInt J Tuberc Lung Dis201418111264126825299856
   PubMed Web of Science ®Google Scholar
• PavordIDGibsonPGInflammometry: the current state of playThorax201267319119222344396
   PubMed Web of Science ®Google Scholar
• YapEChuaWMJayaramLZengIVandalACGarrettJCan we predict sputum eosinophilia from clinical assessment in patients referred to an adult asthma clinic?Intern Med J2013431465221790924
   PubMed Web of Science ®Google Scholar
• KorevaarDAWeaterhofGAWangJDiagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma: a systematic review and meta-analysisLancet Respir Med20153429030025801413
   PubMed Web of Science ®Google Scholar
• WesterhofGAKorevaarDAAmelinkMBiomarkers to identify sputum eosinophilia in different adult asthma phenotypesEur Respir J201546368869626113672
   PubMed Web of Science ®Google Scholar
• ZhangXYSimpsonJLPowellHFull blood count parameters for the detection of asthma inflammatory phenotypesClin Exp Allergy20144491137114524849076
   PubMed Web of Science ®Google Scholar
• FowlerSJTavernierGNivenRHigh blood eosinophil counts predict sputum eosinophilia in patients with severe asthmaJ Allergy Clin Immunol2015135382282425445828
   PubMed Web of Science ®Google Scholar
• WagenerAHde NijsSBLutterRExternal validation of blood eosinophils in asthmaThorax201570211512025422384
   PubMed Web of Science ®Google Scholar
• EltboliOMistryVBarkerBBrightlingCERelationship between blood and bronchial submucosal eosinophilia and reticular basement membrane thickening in chronic obstructive pulmonary diseaseRespirology201520466767025645275
   PubMed Web of Science ®Google Scholar
• BafadhelMMckennaSTerrySBlood eosinophils to direct corticosteroid treatment of exacerbations of chronic obstructive pulmonary disease: a randomised placebo-controlled trialAm J Respir Crit Care Med20121861485522447964
   PubMed Web of Science ®Google Scholar
• PascoeSLocantoreNDransfieldMTBarnesNCPavordIDBlood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone foroate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trialsLancet Respir Med20153643544225878028
   PubMed Web of Science ®Google Scholar
• SiddiquiSHGuasconiAVestboJBlood eosinophils: a biomarker of response to extrafine beclomethasone/formoterol in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2015192452352526051430
   PubMed Web of Science ®Google Scholar
• ChengSLSuKCWangHCPerngDWYangPCChronic obstructive pulmonary disease treated with inhaled medium- or high-dose corticosteroids: a prospective and randomized study focusing on clinical efficacy and the risk of pneumoniaDrug Des Devel Ther20148601607
   Web of Science ®Google Scholar
• JonesPWHardingGBerryPWiklundIChenWHKline LeidyNDevelopment and first validation of the COPD assessment testEur Respir J200934364865419720809
   PubMed Web of Science ®Google Scholar
• Vedel-KroghSNielsenSFLangePVestboJNordestgaardBGBlood eosinophils and exacerbations in COPD: the Copenhagen general population studyAm J Respir Crit Care Med2016193996597426641631
   PubMed Web of Science ®Google Scholar
• Rahimi-RadMHAsgariBHosseinzadehNEishiAEosinopenia as a marker of outcome in acute exacerbation of chronic obstructive pulmonary diseaseMaedica(Buchar)2015101101326225143
   PubMedGoogle Scholar
• PavordIDLettisSLocantoreNBlood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPDThorax201671211812526585525
   PubMed Web of Science ®Google Scholar
• WedzichaJACalverleyPMSeemungalTAHaganGAnsariZStockleyRAThe INSPIRE investigatorsThe prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromideAm J Respir Crit Care Med20081771192617916806
   PubMed Web of Science ®Google Scholar
• CalverleyPPauwelsRVestboJTrial of Inhaled STeroids ANd long-acting beta2 agonists study groupCombined salmeterol and fluticasone in the treatment of chronic obstructive pulmonary disease: a randomised controlled trialLancet2003361935644945612583942
   PubMed Web of Science ®Google Scholar
• ZaniniACherubinoFZampognaECroceSPignattiPSpanevelloABronchial hyperresponsiveness, airway inflammation, and reversibility in patients with chronic obstructive pulmonary diseaseInt J Chron Obstruc Pulmon Dis20151011551161
   PubMed Web of Science ®Google Scholar
• IqbalABarnesNCBrooksJIs blood eosinophil count a predictor of response to bronchodilators in chronic obstructive pulmonary disease? results from post hoc subgroup analysesClin Drug Invertig20153510685688
   PubMed Web of Science ®Google Scholar
• SchleichFNChevremontAPaulusVImportance of concomitant local and systemic eosinophilia in uncontrolled asthmaEur Respir J20144419710824525441
   PubMed Web of Science ®Google Scholar
• KulkarniNSHollinsFSutcliffeAEosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthmaJ Allergy Clin Immunol20101261616920639010
   PubMed Web of Science ®Google Scholar
• WoodruffPGAgustiARocheNSinghDMartinezFJCurrent concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised managementLancet201538599791789179825943943
   PubMed Web of Science ®Google Scholar
• GhebreMABafadhelMDesaiDBiological clustering supports both “Dutch” and “British” hypotheses of asthma and chronic obstructive pulmonary diseaseJ Allergy Clin Immunol20151351637225129678
   PubMed Web of Science ®Google Scholar
• BrusselleGBrackeKTargeting immune pathways for therapy in asthma and chronic obstructive pulmonary diseaseAnn Am Thorac Soc201411Suppl 5S322S32825525740
   PubMedGoogle Scholar