References
- VestboJHurdSSAgustiAGGlobal strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summaryAm J Respir Crit Care Med2013187434736522878278
- BuistASMcBurnieMAVollmerWMInternational variation in the prevalence of COPD (the BOLD Study): a population-based prevalence studyLancet2007370958974175017765523
- BeersMFMorriseyEEThe three R’s of lung health and disease: repair, remodeling, and regenerationJ Clin Invest201112162065207321633173
- RennardSIWachenfeldtKRationale and emerging approaches for targeting lung repair and regeneration in the treatment of chronic obstructive pulmonary diseaseProc Am Thorac Soc20118436837521816994
- LeemanKTFillmoreCMKimCFLung stem and progenitor cells in tissue homeostasis and diseaseCurr Top Dev Biol201410720723324439808
- KimCFJacksonELWoolfendenAEIdentification of bronchioalveolar stem cells in normal lung and lung cancerCell2005121682383515960971
- CurtisSJSinkeviciusKWLiDPrimary tumor genotype is an important determinant in identification of lung cancer propagating cellsCell Stem Cell20107112713320621056
- Nolen-WalstonRDKimCFMazanMRCellular kinetics and modeling of bronchioalveolar stem cell response during lung regenerationAm J Physiol Lung Cell Mol Physiol20082946L1158L116518375744
- BeachyPAKarhadkarSSBermanDMTissue repair and stem cell renewal in carcinogenesisNature2004432701532433115549094
- UngerSCoplandITibboelDPostMDown-regulation of sonic hedgehog expression in pulmonary hypoplasia is associated with congenital diaphragmatic herniaAm J Pathol2003162254755512547712
- WatkinsDNBermanDMBurkholderSGWangBBeachyPABaylinSBHedgehog signalling within airway epithelial progenitors and in small-cell lung cancerNature2003422692931331712629553
- KrauseAXuYJohJOverexpression of sonic hedgehog in the lung mimics the effect of lung injury and compensatory lung growth on pulmonary Sca-1 and CD34 positive cellsMol Ther201018240441219861952
- ZhouXQiuWSathirapongsasutiJFGene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cellsGenomics2013101526327223459001
- WedzichaJASeemungalTACOPD exacerbations: defining their cause and preventionLancet2007370958978679617765528
- AlmansaRSociasLAndaluz-OjedaDViral infection is associated with an increased proinflammatory response in chronic obstructive pulmonary diseaseViral Immunol201225424925322746693
- GorskiSAHuffordMMBracialeTJRecent insights into pulmonary repair following virus-induced inflammation of the respiratory tractCurr Opin Virol20122323324122608464
- HayashiSHoggJCAdenovirus infections and lung diseaseCurr Opin Pharmacol20077323724317446135
- YanZJunCYanCIntraperitoneal injection of cigarette smoke extract induced emphysema, and injury of cardiac and skeletal muscles in BALB/C miceExp Lung Res2013391183123216006
- HeZHChenPChenYComparison between cigarette smoke-induced emphysema and cigarette smoke extract-induced emphysemaTob Induc Dis2015131625814921
- GuedersMMBertholetPPerinFA novel formulation of inhaled doxycycline reduces allergen-induced inflammation, hyperresponsiveness and remodeling by matrix metalloproteinases and cytokines modulation in a mouse model of asthmaBiochem Pharmacol200875251452617950252
- IkedaNHayashiAIwasakiKComprehensive diagnostic bronchoscopy of central type early stage lung cancerLung Cancer200756329530217291623
- Taraseviciene-StewartLDouglasISNana-SinkamPSIs alveolar destruction and emphysema in chronic obstructive pulmonary disease an immune disease?Proc Am Thorac Soc20063868769017065374
- ForonjyRFDaboAJTaggartCCWeldonSGeraghtyPRespiratory syncytial virus infections enhance cigarette smoke induced COPD in micePLoS One201492e9056724587397
- MartinJHelmKRueggPVarella-GarciaMBurnhamEMajkaSAdult lung side population cells have mesenchymal stem cell potentialCytotherapy200810214015118368593
- McQualterJLYuenKWilliamsBBertoncelloIEvidence of an epithelial stem/progenitor cell hierarchy in the adult mouse lungProc Natl Acad Sci U S A201010741414141920080639
- NakamuraYRombergerDJTateLCigarette smoke inhibits lung fibroblast proliferation and chemotaxisAm J Respir Crit Care Med19951515149715037735606
- CantralDESissonJHVeysTRennardSISpurzemJREffects of cigarette smoke extract on bovine bronchial epithelial cell attachment and migrationAm J Physiol19952685 pt 1L723L7287762674
- HeSHeZChenYC-Kit/c-Kit ligand interaction of bone marrow endothelial progenitor cells is influenced in a cigarette smoke extract-induced emphysema modelExp Lung Res201339625826723786491
- DeebRSWaltersMSStrulovici-BarelYChenQGrossSSCrystalRGSmoking-associated disordering of the airway basal stem/progenitor cell metabotypeAm J Respir Cell Mol Biol201654223124026161876
- ShaykhievRCrystalRGEarly events in the pathogenesis of chronic obstructive pulmonary disease. Smoking-induced reprogramming of airway epithelial basal progenitor cellsAnn Am Thorac Soc201411suppl 5S252S25825525728
- StaudtMRBuro-AuriemmaLJWaltersMSAirway basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2014190895595825317467
- ZuoWZhangTWuDZp63(+)Krt5(+) distal airway stem cells are essential for lung regenerationNature2015517753661662025383540
- VaughanAEBrumwellANXiYLineage-negative progenitors mobilize to regenerate lung epithelium after major injuryNature2015517753662162525533958
- WangJCaoJDicksonALPossKDEpicardial regeneration is guided by cardiac outflow tract and hedgehog signallingNature2015522755522623025938716
- MichelottiGAXieGSwiderskaMSmoothened is a master regulator of adult liver repairJ Clin Invest201312362380239423563311
- BellusciSFurutaYRushMGHendersonRWinnierGHoganBLInvolvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesisDevelopment1997124153639006067
- ChenXJinYHouXLiuFWangYSonic hedgehog signaling: evidence for its protective role in endotoxin induced acute lung injury in mouse modelPLoS One20151011e014088626545089
- ChuangPTKawcakTMcMahonAPFeedback control of mammalian hedgehog signaling by the hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lungGenes Dev200317334234712569124
- ZhouXBaronRMHardinMIdentification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIPHum Mol Genet20122161325133522140090
- WangBZhouHYangJAssociation of HHIP polymorphisms with COPD and COPD-related phenotypes in a Chinese Han populationGene2013531110110523994291
- LaoTGlassKQiuWHaploinsufficiency of hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiringGenome Med2015711225763110
- LaoTJiangZYunJHhip haploinsufficiency sensitizes mice to age-related emphysemaProc Natl Acad Sci U S A201611332E4681E468727444019
- TeglundSToftgardRHedgehog beyond medulloblastoma and basal cell carcinomaBiochim Biophys Acta20101805218120820085802