References
- VestboJAgustiAWoutersEFShould we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study teamAm J Respir Crit Care Med201418991022103024552242
- Allen-RameyFCGuptaSDiBonaventuraMDPatient characteristics, treatment patterns, and health outcomes among COPD phenotypesInt J Chron Obstruct Pulmon Dis2012777978723226014
- de OcaMMHalbertRJLopezMVThe chronic bronchitis phenotype in subjects with and without COPD: the PLATINO studyEur Respir J201240283622282547
- OhYMSheenSSParkJHEmphysematous phenotype is an independent predictor for frequent exacerbation of COPDInt J Tuberc Lung Dis201418121407141425517804
- GelbAFChristensonSANadelJAUnderstanding the pathophysiology of the asthma-chronic obstructive pulmonary disease overlap syndromeCurr Opin Pulm Med201622210010526717511
- Izquierdo-AlonsoJLRodriguez-GonzalezmoroJMde Lucas-RamosPPrevalence and characteristics of three clinical phenotypes of chronic obstructive pulmonary disease (COPD)Respir Med2013107572473123419828
- ElbehairyAFRaghavanNChengSPhysiologic characterization of the chronic bronchitis phenotype in GOLD grade IB COPDChest201514751235124525393126
- CaillaudDChanezPEscamillaRAsthma-COPD overlap syndrome (ACOS) vs ‘pure’ COPD: a distinct phenotype?Allergy201772113714527501862
- MiravitllesMCalleMSoler-CatalunaJJClinical phenotypes of COPD: identification, definition and implications for guidelinesArch Bronconeumol2012483869822196477
- HurstJRVestboJAnzuetoASusceptibility to exacerbation in chronic obstructive pulmonary diseaseN Engl J Med2010363121128113820843247
- BlasiFNeriLCentanniSClinical characterization and treatment patterns for the frequent exacerbator phenotype in chronic obstructive pulmonary disease with severe or very severe airflow limitationCOPD2017141152227824270
- MiravitllesMSoler-CatalunaJJCalleMTreatment of COPD by clinical phenotypes: putting old evidence into clinical practiceEur Respir J20134161252125623060631
- WanESDeMeoDLHershCPClinical predictors of frequent exacerbations in subjects with severe chronic obstructive pulmonary disease (COPD)Respir Med2011105458859421145719
- Soler-CatalunaJJRodriguez-RoisinRFrequent chronic obstructive pulmonary disease exacerbators: how much real, how much fictitious?COPD20107427628420673037
- Soler-CatalunaJJCosioBIzquierdoJLConsensus document on the overlap phenotype COPD-asthma in COPDArch Bronconeumol201248933133722341911
- ChaeEJSeoJBSongJWSlope of emphysema index: an objective descriptor of regional heterogeneity of emphysema and an independent determinant of pulmonary functionAJR Am J Roentgenol20101943W248W25520173123
- da SilvaSMPaschoalIADe CapitaniEMCOPD phenotypes on computed tomography and its correlation with selected lung function variables in severe patientsInt J Chron Obstruct Pulmon Dis20161150351327042039
- McGarveyLLeeAJRobertsJCharacterisation of the frequent exacerbator phenotype in COPD patients in a large UK primary care populationRespir Med2015109222823725613107
- AzizZAWellsAUDesaiSRFunctional impairment in emphysema: contribution of airway abnormalities and distribution of parenchymal diseaseAJR Am J Roentgenol200518561509151516304005
- HanMKKazerooniEALynchDAChronic obstructive pulmonary disease exacerbations in the COPDGene study: associated radiologic phenotypesRadiology2011261127428221788524
- DonaldsonGCHurstJRSmithCJIncreased risk of myocardial infarction and stroke following exacerbation of COPDChest201013751091109720022970
- DivoMCoteCde TorresJPComorbidities and risk of mortality in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2012186215516122561964
- HanMKBartholmaiBLiuLXClinical significance of radiologic characterizations in COPDCOPD20096645946719938970
- LeeHUmSJKimYSAssociation of the neutrophil-to-lymphocyte ratio with lung function and exacerbations in patients with chronic obstructive pulmonary diseasePLoS One2016116e015651127258044
- GunayESarinc UlasliSAkarONeutrophil-to-lymphocyte ratio in chronic obstructive pulmonary disease: a retrospective studyInflammation201437237438024078279
- MotegiTJonesRCIshiiTA comparison of three multidimensional indices of COPD severity as predictors of future exacerbationsInt J Chron Obstruct Pulmon Dis2013825927123754870
- AlexopoulosECMalliFMitsikiEFrequency and risk factors of COPD exacerbations and hospitalizations: a nationwide study in Greece (Greek Obstructive Lung Disease Epidemiology and health ecoNomics: GOLDEN study)Int J Chron Obstruct Pulmon Dis2015102665267426715845
- SundhJJohanssonGLarssonKThe phenotype of concurrent chronic bronchitis and frequent exacerbations in patients with severe COPD attending Swedish secondary care unitsInt J Chron Obstruct Pulmon Dis2015102327233426604732
- DonaldsonGCMullerovaHLocantoreNFactors associated with change in exacerbation frequency in COPDRespir Res20131417923899210
- BatesMLFarrellETEldridgeMWAbnormal ventilatory responses in adults born prematurelyN Engl J Med2014370658458524499235
- KirbySEDennisSMJayasingheUWPatient related factors in frequent readmissions: the influence of condition, access to services and patient choiceBMC Health Serv Res201010121620663141
- ThomsenMIngebrigtsenTSMarottJLInflammatory biomarkers and exacerbations in chronic obstructive pulmonary diseaseJAMA2013309222353236123757083
- BhavaniSTsaiCLPerusichSClinical and immunological factors in emphysema progression. Five-year prospective longitudinal exacerbation study of chronic obstructive pulmonary disease (LES-COPD)Am J Respir Crit Care Med2015192101171117826241705
- HesselbacherSERossRSchabathMBCross-sectional analysis of the utility of pulmonary function tests in predicting emphysema in ever-smokersInt J Environ Res Public Health2011851324134021655122
- TulekBKivrakASOzbekSPhenotyping of chronic obstructive pulmonary disease using the modified Bhalla scoring system for high-resolution computed tomographyCan Respir J2013202919623616965
- Feliz-RodriguezDZudaireSCarpioCEvolution of the COPD Assessment Test score during chronic obstructive pulmonary disease exacerbations: determinants and prognostic valueCan Respir J2013205e92e9724093119
- MiravitllesMGarcia-SidroPFernandez-NistalAThe chronic obstructive pulmonary disease assessment test improves the predictive value of previous exacerbations for poor outcomes in COPDInt J Chron Obstruct Pulmon Dis2015102571257926664105
- KerkhofMFreemanDJonesRPredicting frequent COPD exacerbations using primary care dataInt J Chron Obstruct Pulmon Dis2015102439245026609229
- PasqualeMKXuYBakerCLCOPD exacerbations associated with the modified Medical Research Council scale and COPD assessment test among Humana Medicare membersInt J Chron Obstruct Pulmon Dis201611111112126834468