384
Views
31
CrossRef citations to date
0
Altmetric
Review

Acute exacerbations of COPD: risk factors for failure and relapse

, , , , , , , & show all
Pages 2687-2693 | Published online: 08 Sep 2017

References

  • DollHMiravitllesMHealth-related QOL in acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease: a review of the literaturePharmacoeconomics200523434536315853435
  • DonaldsonGCSeemungalTABhowmikAWedzichaJARelationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary diseaseThorax2002571084785212324669
  • AnzuetoALeimerIKestenSImpact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomesInt J Chron Obstruct Pulmon Dis2009424525119657398
  • SeemungalTADonaldsonGCBhowmikAJeffriesDJWedzichaJATime course and recovery of exacerbations in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med200016151608161310806163
  • Pozo-RodriguezFLopez-CamposJLAlvarez-MartinezCJClinical audit of COPD patients requiring hospital admission in Spain: AUDIPOC studyPLoS One201277e4215622911875
  • PatilSPKrishnanJALechtzinNDietteGBIn-hospital mortality following acute exacerbations of chronic obstructive pulmonary diseaseArch Intern Med2003163101180118612767954
  • HalpinDMGDecramerMCelliBDietteGBExacerbation frequency and course of COPDInt J COPD20127653661
  • PasqualeMKSunSXSongFHartnettHJStemkowskiSAImpact of exacerbation on health care cost and resource utilization in chronic obstructive pulmonary disease patients with chronic bronchitis from a predominantly Medicare populationInt J COPD20127757764
  • StrasselsSASmithDHSullivanSDMahajanPSThe cost of treating COPD in the United StatesChest200111934435211171708
  • FitzGeraldJMHaddonJMBradly-KennedyCKuramotoLFordGTRUSIC Study GroupResource use study in COPD (RUSIC): a prospective study to quantify the effects of COPD exacerbations on health care resource use among COPD patientsCan Respir J200714314515217464378
  • ElixhauserAAuDHPodulkaJReadmissions for chronic obstructive pulmonary disease, 2008: statistical brief #121Healthcare Cost and Utilization Project (HCUP) Statistical BriefsRockville, MDAgency for Healthcare Research and Quality (US)2011
  • HurstJRDonaldsonGCQuintJKGoldringJJBaghai-RavaryRWedzichaJATemporal clustering of exacerbations in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2009179536937419074596
  • MakrisDMoschandreasJDamianakiAExacerbations and lung function decline in COPD: new insights in current and ex-smokersRespir Med200710161305131217112715
  • Soler-CataluñaJJMartínez-GarcíaMARomán SánchezPSalcedoENavarroMOchandoRSevere acute exacerbations and mortality in patients with chronic obstructive pulmonary diseaseThorax20056092593116055622
  • KrumholzHMParentEMTuNReadmission after hospitalization for congestive heart failure among Medicare beneficiariesArch Intern Med19971571991048996046
  • FriedmanBJiangHJElixhauserACostly hospital readmissions and complex chronic illnessInquiry200845440842119209836
  • BakerCLZouKHSuJRisk assessment of readmissions following an initial COPD-related hospitalizationInt J Chron Obstruct Pulmon Dis2013855155924348031
  • NantsupawatTLimsuwatCNugentKFactors affecting chronic obstructive pulmonary disease early rehospitalizationChron Respir Dis201292939822399574
  • Centers for Disease Control and Prevention (CDC)Deaths from chronic obstructive pulmonary disease. United States, 2000–2005MMWR Morb Mortal Wkly Rep200857451229123219008792
  • OverbeekJAPenning-van BeestFJBalpMMDekhuijzenPNHeringsRMBurden of Exacerbations in Patients with Moderate to Very Severe COPD in the Netherlands: a real-life studyCOPD201512213214324960237
  • ChowAWHallCBKleinJOEvaluation of new anti-infective drugs for the treatment of respiratory tract infectionsClin Infect Dis199215S62S881477253
  • WilsonRAnzuetoAMiravitllesMA novel study design for antibiotic trials in acute exacerbations of COPD: MAESTRAL methodologyInt J Chron Obstruct Pulmon Dis2011637338321760724
  • DanielsJMSnijdersDde GraaffCSVlaspolderFJansenHMBoersmaWGAntibiotics in addition to systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2010181215015719875685
  • ErblandMLDeupreeRHNiewoehnerDESystemic corticosteroids in chronic obstructive pulmonary disease exacerbations (SCCOPE): rationale and design of an equivalence trial. Veterans Administration Cooperative Trials SCCOPE Study GroupControl Clin Trials19981944044179683314
  • NiewoehnerDEErblandMLDeupreeRHEffect of systemic glucocorticoids on exacerbations of chronic obstructive pulmonary disease. Department of Veterans Affairs Cooperative Study GroupN Engl J Med1999340251941194710379017
  • VermeerschKGabrovskaMDeslypereGThe Belgian trial with azithromycin for acute COPD exacerbations requiring hospitalization: an investigator-initiated study protocol for a multicenter, randomized, double-blind, placebo-controlled trialInt J Chron Obstruct Pulmon Dis20161168769627099485
  • JencksSFWilliamsMVColemanEARehospitalizations among patients in the Medicare fee-for-service programN Engl J Med2009360141418142819339721
  • CrisafulliEGuerreroMChettaATorresAReadmission in COPD patients: should we consider it a marker of quality of care or a marker of a more severe disease with a worse prognosis?Eur Respir J201648127928127365513
  • GuerreroMCrisafulliELiapikouAReadmission for acute exacerbation within 30 days of discharge is associated with a subsequent progressive increase in mortality risk in COPD patients: a long-term observational studyPLoS One2016113e015073726943928
  • KimSEmermanCLCydulkaRKMARC InvestigatorsProspective multicenter study of relapse following emergency department treatment of COPD exacerbationChest2004125247348114769727
  • CrisafulliEOrtegaSTorresAPredictors of readmission in a period of 30 days or less in acute exacerbation of chronic obstructive pulmonary diseaseClin Pulm Med2015224172176
  • ZapateroABarbaRRuizJMalnutrition and obesity: influence in mortality and readmissions in chronic obstructive pulmonary disease patientsJ Hum Nutr Diet201326suppl 1162223656492
  • SharifRParekhTMPiersonKSKuoYFSharmaGPredictors of early readmission among patients 40 to 64 years of age hospitalized for chronic obstructive pulmonary diseaseAnn Am Thorac Soc201411568569424784958
  • ChanFWWongFYYamCHRisk factors of hospitalization and readmission of patients with COPD in Hong Kong population: analysis of hospital admission recordsBMC Health Serv Res20111118621831287
  • Garcia-AymerichJFarreroEFélezMAEstudi del Factors de Risc d’Agudització de la MPOC investigatorsRisk factors of readmission to hospital for a COPD exacerbation: a prospective studyThorax200358210010512554887
  • GonzálezCServeraEMarínJImportance of noninvasively measured respiratory muscle overload among the causes of hospital readmission of COPD patientsChest2008133494194718263690
  • LinJXuYWuXRisk factors associated with chronic obstructive pulmonary disease early readmissionCurr Med Res Opin201430231532024156615
  • AlmagroPBarreiroBOchoa de EchaguenARisk factors for hospital readmission in patients with chronic obstructive pulmonary diseaseRespiration200673331131716155352
  • VilaróJRamirez-SarmientoAMartínez-LlorensJMGlobal muscle dysfunction as a risk factor of readmission to hospital due to COPD exacerbationsRespir Med2010104121896190220541383
  • CaoZOngKCEngPTanWCNgTPFrequent hospital readmissions for acute exacerbation of COPD and their associated factorsRespirology200611218819516548905
  • GudmundssonGGislasonTJansonCRisk factors for rehospitalisation in COPD: role of health status, anxiety and depressionEur Respir J200526341441916135721
  • CoventryPAGemmellIToddCJPsychosocial risk factors for hospital readmission in COPD patients on early discharge services: a cohort studyBMC Pulm Med2011114922054636
  • WongAWGanWQBurnsJSinDDvan EedenSFAcute exacerbation of chronic obstructive pulmonary disease: influence of social factors in determining length of hospital stay and readmission ratesCan Respir J200815736136418949105
  • DahlénIJansonCAnxiety and depression are related to the outcome of emergency treatment in patients with obstructive pulmonary diseaseChest200212251633163712426264
  • de BatlleJMendezMRomieuIPAC-COPD Study GroupCured meat consumption increases risk of readmission in COPD patientsEur Respir J201240355556022408205
  • OzyilmazEKokturkNTeksutGTatliciogluTUnsuspected risk factors of frequent exacerbations requiring hospital admission in chronic obstructive pulmonary diseaseInt J Clin Pract201367769169723758448
  • WilsonRAnzuetoAMiravitllesMPrognostic factors for clinical failure of exacerbations in elderly outpatients with moderate-to-severe COPDInt J Chron Obstruct Pulmon Dis20151098599326082623
  • HartlSLopez-CamposJLPozo-RodriguezFRisk of death and readmission of hospital-admitted COPD exacerbations: European COPD AuditEur Respir J201647111312126493806
  • SteerJNormanEMAfolabiOAGibsonGJBourkeSCDyspnoea severity and pneumonia as predictors of in-hospital mortality and early readmission in acute exacerbations of COPDThorax201267211712121896712
  • AlmagroPCabreraFJDiezJWorking Group on, COPD Spanish Society of Internal MedicineComorbidities and short-term prognosis in patients hospitalized for acute exacerbation of COPD: the EPOC en Servicios de medicina interna (ESMI) studyChest201214251126113323303399
  • McGhanRRadcliffTFishRSutherlandERWelshCMakeBPredictors of rehospitalization and death after a severe exacerbation of COPDChest200713261748175517890477
  • WangYCLinJMLiCYLeeLTGuoYLSungFCPrevalence and risks of chronic airway obstruction: a population cohort study in TaiwanChest2007131370571017356083
  • CrisafulliETorresAHuertaAC-reactive protein at discharge, diabetes mellitus and ≥1 hospitalization during previous year predict early readmission in patients with acute exacerbation of chronic obstructive pulmonary diseaseCOPD201512330631425279441
  • BhattSPKhandelwalPNandaSStoltzfusJCFioravantiGTSerum magnesium is an independent predictor of frequent readmissions due to acute exacerbation of chronic obstructive pulmonary diseaseRespir Med20081027999100318396393
  • DuQJinJLiuXSunYBronchiectasis as a comorbidity of chronic obstructive pulmonary disease: a systematic review and meta-analysisPLoS One2016113e015053226978269
  • MaoBLuHWLiMHThe existence of bronchiectasis predicts worse prognosis in patients with COPDSci Rep201551096126077673
  • JinJYuWLiSLuLLiuXSunYFactors associated with bronchiectasis in patients with moderate-severe chronic obstructive pulmonary diseaseMedicine (Baltimore)20169529e421927442646
  • Martínez-GarcíaMÁSoler-CataluñaJJDonat SanzYFactors associated with bronchiectasis in patients with COPDChest201114051130113721546440
  • FanerRTal SingerRRileyJLesson from ECLIPSE: a review of COPD biomarkersThorax20146966667224310110
  • ThomsenMIngebrigtsenTSMarottJLInflammatory biomarkers and exacerbations in chronic obstructive pulmonary diseaseJAMA2013309222353236123757083
  • HurstJRVestboJAnzuetoASusceptibility to exacerbation in chronic obstructive pulmonary diseaseN Engl J Med20103631128113820843247
  • PereraWRHurstJRWilkinsonTMInflammatory changes, recovery and recurrence at COPD exacerbationEur Respir J200729352753417107990
  • SethiSWronaCEschbergerKLobbinsPCaiXMurphyTFInflammatory profile of new bacterial strain exacerbations of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2008177549149718079493
  • CrisafulliETorresAHuertaAPredicting in-hospital treatment failure (≤7 days) in patients with COPD exacerbation using antibiotics and systemic steroidsCOPD2016131829226451913
  • HuGWuYZhouYPrognostic role of D-dimer for in-hospital and 1-year mortality in exacerbations of COPDInt J Chron Obstruct Pulmon Dis2016112729273627843309
  • SinDDHollanderZDeMarcoMLMxManusBMNgRTBiomarker development for COPD: From discovery to clinical implementationAm J Respir Crit Care Med2015192101162117026176936
  • Cabrera-RubioRGarcia-NúñezMSetóLMicrobiome diversity in the bronchial tracts of patients with chronic obstructive pulmonary diseaseJ Clin Microbiol201250113562356822915614
  • HuangYJSethiSMurphyTNariyaSBousheyHALynchSVAirway microbiome dynamics in exacerbations of chronic obstructive pulmonary diseaseJ Clin Microbiol20145282813282324850358
  • PatelISeemungalTWilksMLloyd-OwenSJDonaldsonGCWedzichaJARelationship between bacterial colonisation and the frequency, character, and severity of COPD exacerbationsThorax200257975976412200518
  • MonsoERosellABonetGRisk factors for lower airway bacterial colonization in chronic bronchitisEur Respir J199913233834210065678
  • MillaresLFerrariRGallegoMBronchial microbiome of severe COPD patients colonised by Pseudomonas aeruginosaEur J Clin Microbiol Infect Dis20143371101111124449346
  • WilkinsonTMDonaldsonGCHurstJRSeemungalTAWedzichaJAEarly therapy improves outcomes of exacerbations of chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2004169121298130314990395
  • MiravitllesMKruesmannFHaverstockDPerroncelRChoudhriSHArvisPSputum colour and bacteria in chronic bronchitis exacerbations: a pooled analysisEur Respir J20123961354136022034649
  • ChowAWHallCBKleinJOKammerRBMeyerRDRemingtonJSEvaluation of new anti-infective drugs for the treatment of respiratory tract infections. Infectious Diseases Society of America and the Food and Drug AdministrationClin Infect Dis199215suppl 1S62S681477253
  • WhiteAJGompertzSBayleyDLResolution of bronchial inflammation is related to bacterial eradication following treatment of exacerbations of chronic bronchitisThorax200358868068512885984
  • SolerNEsperattiMEwigSHuertaAAgustíCTorresASputum purulence-guided antibiotic use in hospitalised patients with exacerbations of COPDEur Respir J20124061344135322523352
  • StolzDChrist-CrainMBingisserRAntibiotic treatment of exacerbations of COPD: a randomized, controlled trial comparing procalcitonin-guidance with standard therapyChest2007131191917218551
  • WilsonRAllegraLHuchonGShort and long-term outcomes of moxifloxacin compared to standard antibiotic treatment in acute exacerbations of chronic bronchitisChest200412595396415006954
  • Ruiz-GonzalezAGimenezAGomez-ArbonesXOpen-label, randomized comparison trial of long-term outcomes of levofloxacin versus standard antibiotic therapy in acute exacerbations of chronic obstructive pulmonary diseaseRespirology200712111712117207036
  • LodeHEllerJLinnhoffAIoanasMEvaluation of therapy free interval in COPD patients study group. Levofloxacin versus clarithromycin in COPD exacerbation: focus on exacerbation-free intervalEur Respir J20042494795315572537
  • ChodoshSSchreursASiamiGEfficacy of oral ciprofloxacin vs. clarithromycin for treatment of acute bacterial exacerbations of chronic bronchitisClin Infect Dis1998277307389798025
  • WilsonRAnzuetoAMiravitllesMMoxifloxacin vs amoxicillin/clavulanic acid in outpatient acute exacerbations of COPD: MAESTRAL resultsEur Respir J201240172722135277
  • EisnerMDTrupinLKatzPPDevelopment and validation of a survey-based COPD severity scoreChest200512761890189715947299
  • BurrowsBEarleRHCourse and prognosis of chronic obstructive lung disease: a prospective study of 200 patientsN Engl J Med19692803974045763088
  • MiravitllesMIzquierdoIHerrejónAESFERA InvestigatorsCOPD severity score as a predictor of failure in exacerbations of COPD. The ESFERA studyRespir Med2011105574074721227672