Gene and miRNA expression profiles in PBMCs from patients with severe and mild emphysema and PiZZ alpha1-antitrypsin deficiency

References

• LozanoRNaghaviMForemanKGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet201238098592095212823245604
   PubMed Web of Science ®Google Scholar
• LomasDAMahadevaRAlpha-1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapyJ Clin Invest2002110111585159012464660
   PubMed Web of Science ®Google Scholar
• DeMeoDLSilvermanEKAlpha 1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema riskThorax200459325926414985567
   PubMed Web of Science ®Google Scholar
• BlancoIBuenoPDiegoIAlpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide: an updateInt J Chron Obstruct Pulmon Dis20171256156928243076
   PubMed Web of Science ®Google Scholar
• Tirado-CondeGLaraBCasasFFactors associated with the evolution of lung function in patients with alpha-1 antitrypsin deficiency in the Spanish registryArch Bronconeumol2011471049550321798656
   PubMed Web of Science ®Google Scholar
• TanashHANilssonPMNilssonJAPituilainenEClinical course and prognosis of never smokers with severe AATD (PiZ)Thorax200863121091109518682522
   PubMed Web of Science ®Google Scholar
• The Alpha-1-antitrypsin deficiency Registry Study GroupSurvival and FEV1 decline in individuals with severe deficiency of alpha-1-antitrypsinAm J Respir Crit Care Med1998158149599655706
   PubMed Web of Science ®Google Scholar
• SeersholmNKok-JensenADirksenADecline in FEV1 among patients with severe hereditary ATAD type PiZAm J Respir Crit Care Med19951526 Pt 1192219258520756
   PubMed Web of Science ®Google Scholar
• ChenWHongYQMengZLBioinformatics analysis of molecular mechanisms of chronic obstructive pulmonary diseaseEur Rev Med Pharmacol Sci201418233557356325535123
   PubMed Web of Science ®Google Scholar
• WeiLXuDQianYComprehensive analysis of gene-expression profile in chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis2015101103110926089660
   PubMed Web of Science ®Google Scholar
• FanerRCruzTCasserrasTNetwork analysis of lung transcriptomics reveals a distinct B-Cell signature in emphysemaAm J Respir Crit Care Med2016193111242125326735770
   PubMed Web of Science ®Google Scholar
• FriedmanRCFarhKKBurgeCBBartelDPMost mammalian mRNAs are conserved targets of microRNAsGenome Res20091919210518955434
   PubMed Web of Science ®Google Scholar
• AnguloMLecuonaESznajderJIRole of microRNAs in lung diseaseArch Bronconeumol201248932533022607962
   PubMed Web of Science ®Google Scholar
• Nana-SinkamSPHunterMGNuovoGJIntegrating the MicroR-Nome into the study of lung diseaseAm J Respir Crit Care Med2009179141018787215
   PubMed Web of Science ®Google Scholar
• TomankovaTPetrekMKriegovaEInvolvement of microRNAs in physiological and pathological processes in the lungRespir Res20101115921092244
   PubMed Web of Science ®Google Scholar
• PagdinTLavenderPMicroRNAs in lung diseasesThorax20126718318421836155
   PubMed Web of Science ®Google Scholar
• RaponiMDosseyLJatkoeTMicroRNA classifiers for predicting prognosis of squamous cell lung cancerCancer Res200969145776578319584273
   PubMed Web of Science ®Google Scholar
• EzzieMECrawfordMChoJHGene expression networks in COPD: microRNA and mRNA regulationThorax201267212213121940491
   PubMed Web of Science ®Google Scholar
• HobbsBDHershCPIntegrative genomics of chronic obstructive pulmonary diseaseBiochem Biophys Res Commun2014452227628625078622
   PubMed Web of Science ®Google Scholar
• ChenZHKimHPRyterSWChoiAMIdentifying targets for COPD treatment through gene expression analysesInt J Chron Obstruct Pulmon Dis20083335937018990963
   PubMedGoogle Scholar
• WuXSunXChenCBaiCWangXDynamic gene expressions of peripheral blood mononuclear cells in patients with acute exacerbation of chronic obstructive pulmonary disease: a preliminary studyCrit Care201418650825407108
   PubMed Web of Science ®Google Scholar
• American Thoracic Society/European Respiratory Statement: Standards for the diagnosis and management of individuals with alpha-1 antitrypsin deficiencyAm J Respir Crit Care Med2003168781890014522813
   PubMed Web of Science ®Google Scholar
• AggarwalNKoepkeJMatamalaNAlpha-1 antitrypsin regulates transcriptional levels of serine proteases in blood mononuclear cellsAm J Respir Crit Care Med201619391065106727128707
   PubMed Web of Science ®Google Scholar
• MiravitllesMSoler-CataluñaJJCalleMSpanish COPD guidelines (GesEPOC) 2017. Pharmacological treatment of stable chronic obstructive pulmonary diseaseArch Bronconeumol201753632433528477954
   PubMed Web of Science ®Google Scholar
• CasasFBlancoIMartínezMTIndications for active case searches and intravenous alpha-1 antitrypsin treatment for patients with alpha-1 antitrypsin deficiency chronic obstructive pulmonary disease: an updateArch Bronconeumol201551418519225027067
   PubMed Web of Science ®Google Scholar
• CarvalhoBSIrizarryRAA framework for oligonucleotide microarray preprocessingBioinformatics201026192363236720688976
   PubMed Web of Science ®Google Scholar
• IrizarryRAHobbsBCollinFExploration, normalization, and summaries of high density oligonucleotide array probe level dataBiostatistics20034224926412925520
   PubMed Web of Science ®Google Scholar
• LeekJTJohnsonWEParkerHS2016sva: Surrogate Variable Analysis. R package version 3.20.0 Available from: https://bioconductor.riken.jp/packages/3.0/bioc/html/sva.htmlAccessed October 18, 2017
   Google Scholar
• JohnsonWELiCRabinovicAAdjusting batch effects in microarray expression data using empirical Bayes methodsBiostatistics20078111812716632515
   PubMed Web of Science ®Google Scholar
• SmythGKLinear models and empirical Bayes methods for assessing differential expression in microarray experimentsStat Appl Genet Mol Biol20043 Article3
   PubMedGoogle Scholar
• AshburnerMBallCABlakeJAGene ontology: tool for the unification of biology. the gene ontology consortiumNat Genet2000251252910802651
   PubMed Web of Science ®Google Scholar
• RuYKechrisKJTabakoffBThe multiMiR R package and database: integration of microRNA-target interactions along with their disease and drug associationsNucleic Acids Res20144217e13325063298
   PubMed Web of Science ®Google Scholar
• AgustiAGNogueraASauledaJSalaEPonsJBusquetsXSystemic effects of chronic obstructive pulmonary diseaseEur Respir J200321234736012608452
   PubMed Web of Science ®Google Scholar
• JanciauskieneSMBalsRKoczullaRVogelmeierCKöhnleinTWelteTThe discovery of α1-antitrypsin and its role in health and diseaseRespir Med201110581129113921367592
   PubMed Web of Science ®Google Scholar
• GolponHAColdrenCDZamoraMREmphysema lung tissue gene expression profilingAm J Respir Cell Mol Biol200431659560015284076
   PubMed Web of Science ®Google Scholar
• LeeSLSadovskyYSwirnoffAHLuteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)Science1996273121912218703054
   PubMed Web of Science ®Google Scholar
• BaronVTPioRJiaZMercolaDEarly growth response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancerBr J Cancer2015112475576425633035
   PubMed Web of Science ®Google Scholar
• UnderwoodDCOsbornRRBochnowiczSSB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lungAm J Physiol Lung Cell Mol Physiol20002795L895L90211053025
   PubMed Web of Science ®Google Scholar
• JohnsonGLLapadatRMitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesScience200229856001911191212471242
   PubMed Web of Science ®Google Scholar
• SchuligaMNF-KappaB in chronic inflammatory airway diseaseBiomolecules2015531266128326131974
   PubMed Web of Science ®Google Scholar
• YamamotoCYonedaTYoshikawaMAirway inflammation in COPD assessed by sputum levels of interleukin-8Chest199711225055109266891
   PubMed Web of Science ®Google Scholar
• PastoreNAttanasioSGraneseBActivation of the c-Jun N-terminal kinase pathway aggravates proteotoxicity of hepatic mutant Z alpha1-antitrypsinHepatology20176561865187428073160
   PubMed Web of Science ®Google Scholar
• HuangJTWangJSrivastavaVSenSLiuSMMicroRNA machinery genes as novel biomarkers for cancerFront Oncol2014411324904827
   PubMedGoogle Scholar
• SatoTLiuXNelsonAReduced MiR-146a increases prostaglandin E2 in chronic obstructive pulmonary disease fibroblastsAm J Respir Crit Care Med201018281020102920522791
   PubMed Web of Science ®Google Scholar
• Van PottelbergeGRMestdaghPBrackeKRMicroRNA expression in induced sputum of smokers and patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2011183789890621037022
   PubMed Web of Science ®Google Scholar
• TomankovaTPetrekMKriegovaEInvolvement of microRNAs in physiological and pathological processes in the lungRespir Res20101115921092244
   PubMed Web of Science ®Google Scholar
• MorettoNVolpiGPastoreFFacchinettiFAcrolein effects in pulmonary cells: relevance to chronic obstructive pulmonary diseaseAnn NY Acad Sci20121259394622758635
   PubMed Web of Science ®Google Scholar
• GraffJWPowersLSDicksonAMCigarette smoking decreases global microRNA expression in human alveolar macrophagesPLoS One201278e4406622952876
   PubMed Web of Science ®Google Scholar
• WangYHeYAbrahamBCystosolic, autocrine alpha-1 proteinase inhibitor (A1P1) inhibits caspase-1 blocks IL-1 beta dependent cytokine release in monocytesPLoS One2012711e5107823226468
   PubMed Web of Science ®Google Scholar
• StockleyRABayleyDLUnsalIDowsonLJThe effect of augmentation therapy on bronchial inflammation in alpha1 antitrypsin deficiencyAm J Respir Crit Care Med2002165111494149812045122
   PubMed Web of Science ®Google Scholar
• SchimidSTKoepkeJDreselMThe effects of weekly augmentation therapy in patients with PiZZ alpha-1 antitrypsin deficiencyInt J Chron Obstruct Pulmon Dis2012768769623055718
   PubMed Web of Science ®Google Scholar
• OlfertIMMalekMHEaganTMWagnerHWagnerPDInflammatory cytokine response to exercise in alpha-1-antitrypsin deficient COPD patients ‘on’ or ‘off’ augmentation therapyBMC Pulm Med20141410624975928
   PubMed Web of Science ®Google Scholar