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Original Research

Morphometric analysis of mitochondria in lymphocytes of patients with exacerbations of chronic obstructive pulmonary disease – pilot study

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Pages 2313-2318 | Published online: 30 Jul 2018

References

  • VogelmeierCFCrinerGJMartinezFJGlobal strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD Executive SummaryAm J Respir Crit Care Med2017195555758228128970
  • HancockDBEijgelsheimMWilkJBMeta-analyses of genome-wide association studies identify multiple loci associated with pulmonary functionNat Genet2010421455220010835
  • PillaiSGGeDZhuGA genome-wide association study in chronic obstructive pulmonary disease (COPD): identification of two major susceptibility lociPLoS Genet200953e100042119300482
  • WilkJBChenT-HGottliebDJA genome-wide association study of pulmonary function measures in the Framingham Heart StudyPLoS Genet200953e100042919300500
  • HunninghakeGMChoMHTesfaigziYMMP12, lung function, and COPD in high-risk populationsN Engl J Med2009361272599260820018959
  • LambrechtsDBuysschaertIZanenPThe 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysemaAm J Respir Crit Care Med2010181548649320007924
  • ZöllerBLiXSundquistJSundquistKFamilial transmission of chronic obstructive pulmonary disease in adoptees: a Swedish nationwide family studyBMJ Open201554e007310
  • BiałasAJSitarekPMiłkowska-DymanowskaJPiotrowskiWJGórskiPThe role of mitochondria and oxidative/antioxidative imbalance in pathobiology of chronic obstructive pulmonary diseaseOxid Med Cell Longev20162016780857628105251
  • GórkaKSojaJJakiełaBRelationship between the thickness of bronchial wall layers, emphysema score, and markers of remodeling in bronchoalveolar lavage fluid in patients with chronic obstructive pulmonary diseasePol Arch Med Wewn2016126640241027362393
  • SeemungalTADonaldsonGCPaulEABestallJCJeffriesDJWedzichaJAEffect of exacerbation on quality of life in patients with chronic obstructive pulmonary diseaseAm J Respir Crit Care Med19981575 Pt 1141814229603117
  • WedzichaJASeemungalTARCOPD exacerbations: defining their cause and preventionLancet2007370958978679617765528
  • ConnorsAFDawsonNVThomasCOutcomes following acute exacerbation of severe chronic obstructive lung disease. The SUPPORT investigators (Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments)Am J Respir Crit Care Med19961544 Pt 19599678887592
  • HoogendoornMHoogenveenRTRutten-van MölkenMPVestboJFeenstraTLCase fatality of COPD exacerbations: a meta-analysis and statistical modelling approachEur Respir J201137350851520595157
  • GadgilAZhuXSciurbaFCDuncanSRAltered T-cell phenotypes in chronic obstructive pulmonary diseaseProc Am Thorac Soc20063648748816921122
  • CurtisJLFreemanCMHoggJCThe immunopathogenesis of chronic obstructive pulmonary disease: insights from recent researchProc Am Thorac Soc20074751252117878463
  • GadgilADuncanSRRole of T-lymphocytes and pro-inflammatory mediators in the pathogenesis of chronic obstructive pulmonary diseaseInt J Chron Obstruct Pulmon Dis20083453154119281072
  • LimSCJuJYChiSYApoptosis of T lymphocytes isolated from peripheral blood of patients with acute exacerbation of chronic obstructive pulmonary diseaseYonsei Med J201152458158721623599
  • HodgeSJHodgeGLReynoldsPNScicchitanoRHolmesMIncreased production of TGF-beta and apoptosis of T lymphocytes isolated from peripheral blood in COPDAm J Physiol Lung Cell Mol Physiol20032852L492L49912851215
  • PolverinoFSeysLJMBrackeKROwenCAB cells in chronic obstructive pulmonary disease: moving to center stageAm J Physiol Lung Cell Mol Physiol20163114L687L69527542809
  • HanX-JLuY-FLiS-ACaM kinase I alpha-induced phosphorylation of Drp1 regulates mitochondrial morphologyJ Cell Biol2008182357358518695047
  • DagdaRKCherraSJKulichSMTandonAParkDChuCTLoss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fissionJ Biol Chem200928420138431385519279012
  • BishopJBTaniYWittKMitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudineToxicol Sci200481251251715229369
  • Core TeamRR: A Language and Environment for Statistical ComputingVienna, Austria2016
  • HodgeSHodgeGHolmesMReynoldsPNIncreased peripheral blood T-cell apoptosis and decreased Bcl-2 in chronic obstructive pulmonary diseaseImmunol Cell Biol200583216016615748212
  • ChanDCMitochondrial fusion and fission in mammalsAnnu Rev Cell Dev Biol200622799916704336
  • GomesLCDi BenedettoGScorranoLDuring autophagy mitochondria elongate, are spared from degradation and sustain cell viabilityNat Cell Biol201113558959821478857
  • HoffmannRFZarrintanSBrandenburgSMProlonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cellsRespir Res2013149724088173
  • KaasikASafiulinaDZharkovskyAVekslerVRegulation of mitochondrial matrix volumeAm J Physiol Cell Physiol20072921C157C16316870828
  • TuderRMZhenLChoCYOxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockadeAm J Respir Cell Mol Biol2003291889712600822
  • StudentThe probable error of a meanBiometrika19086125
  • de WinterJCFUsing the Student’s t-test with extremely small sample sizesPract Assess Res Eval20131810112