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Review

Defining the role of neutrophil-to-lymphocyte ratio in COPD: a systematic literature review

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Pages 3651-3662 | Published online: 05 Nov 2018

References

  • VogelmeierCFCrinerGJMartinezFJGlobal strategy for the diagnosis, management, and prevention of chronic obstructive lung disease 2017 report. GOLD executive summaryAm J Respir Crit Care Med2017195555758228128970
  • LozanoRNaghaviMForemanKGlobal and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010Lancet201238098592095212823245604
  • MathersCDLoncarDProjections of global mortality and burden of disease from 2002 to 2030PLoS Med2006311e44217132052
  • MacneeWPathogenesis of chronic obstructive pulmonary diseaseProc Am Thorac Soc20052425826616267346
  • WalterREWilkJBLarsonMGSystemic inflammation and COPD: the Framingham Heart StudyChest20081331192517908709
  • ZhouXLiQZhouXExacerbation of Chronic Obstructive Pulmonary DiseaseCell Biochem Biophys201573234935527352322
  • GroenewegenKHPostmaDSHopWCIncreased systemic inflammation is a risk factor for COPD exacerbationsChest2008133235035718198263
  • SethiSMurphyTFInfection in the pathogenesis and course of chronic obstructive pulmonary diseaseN Engl J Med2008359222355236519038881
  • KurtipekEBekciTTKesliRSamiSSTerziYThe role of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in exacerbation of chronic obstructive pulmonary diseaseJ Pak Med Assoc201565121283128726627508
  • TaylanMDemirMKayaHAlterations of the neutrophil-lymphocyte ratio during the period of stable and acute exacerbation of chronic obstructive pulmonary disease patientsClin Respir J Epub201586
  • CedrésSTorrejonDMartínezANeutrophil to lymphocyte ratio (NLR) as an indicator of poor prognosis in stage IV non-small cell lung cancerClin Transl Oncol2012141186486922855161
  • WalshSRCookEJGoulderFJustinTAKeelingNJNeutrophil-lymphocyte ratio as a prognostic factor in colorectal cancerJ Surg Oncol200591318118416118772
  • NúñezJNúñezEBodíVUsefulness of the neutrophil to lymphocyte ratio in predicting long-term mortality in ST segment elevation myocardial infarctionAm J Cardiol2008101674775218328833
  • TurkmenKErdurFMOzcicekFPlatelet-to-lymphocyte ratio better predicts inflammation than neutrophil-to-lymphocyte ratio in end-stage renal disease patientsHemodial Int201317339139623522328
  • MoherDLiberatiATetzlaffJAltmanDGPRISMA GroupPreferred reporting items for systematic reviews and meta-analyses: the PRISMA statementAnn Intern Med2009151426426919622511
  • WellsGASheaBO’ConnellDThe Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomized studies in meta-analyses Available from: www.ohrica/programs/clinical_epidemiology/oxford.aspAccessedJanuary 10, 2018
  • ViswanathanMPatnodeCDBerkmanNDRecommendations for assessing the risk of bias in systematic reviews of health-care interventionsJ Clin Epidemiol201897263429248724
  • HozoSPDjulbegovicBHozoIEstimating the mean and variance from the median, range, and the size of a sampleBMC Med Res Methodol2005511315840177
  • SaltürkCKarakurtZAdiguzelNDoes eosinophilic COPD exacerbation have a better patient outcome than non-eosinophilic in the intensive care unit?Int J Chron Obstruct Pulmon Dis2015101837184626392758
  • DumanDAksoyEAgcaMCThe utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophiliaInt J Chron Obstruct Pulmon Dis2015102469247826648709
  • KumarPLawSSriramKBEvaluation of platelet lymphocyte ratio and 90-day mortality in patients with acute exacerbation of chronic obstructive pulmonary diseaseJ Thorac Dis2017961509151628740663
  • GünayESarınç UlaşlıSAkarONeutrophil-to-lymphocyte ratio in chronic obstructive pulmonary disease: a retrospective studyInflammation201437237438024078279
  • BilirBAltıntaşNAydınMThe Predictive Role of Neutrophil to Lymphocyte ratio in Chronic Obstructive Pulmonary DiseaseEur J Gen Med2016132105110
  • InEKuluöztürkMÖnerÖDeveciFThe Importance of Neutrophil-to-Lymphocyte Ratio in Chronic Obstructive Pulmonary DiseaseTurk Thorac J2016172414629404122
  • LeeSJLeeHRLeeTWUsefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary disease: a prospective observational studyKorean J Intern Med201631589189827017385
  • YousefAMAlkhiaryWRole of neutrophil to lymphocyte ratio in prediction of acute exacerbation of chronic obstructive pulmonary diseaseEgypt J Chest Dis Tuberc20176614348
  • XiongWXuMZhaoYWuXPudasainiBLiuJMCan we predict the prognosis of COPD with a routine blood test?Int J Chron Obstruct Pulmon Dis20171261562528243079
  • FarahRIbrahimRNassarMNajibDZivonyYEshelEThe neutrophil/lymphocyte ratio is a better addition to C-reactive protein than CD64 index as a marker for infection in COPDPanminerva Med201759320320928185443
  • SørensenAKHolmgaardDBMygindLHJohansenJPedersenCNeutrophil-to-lymphocyte ratio, calprotectin and YKL-40 in patients with chronic obstructive pulmonary disease: correlations and 5-year mortality – a cohort studyJ Inflamm201512120
  • FurutateRIshiiTMotegiTThe neutrophil to lymphocyte ratio is related to disease severity and exacerbation in patients with chronic obstructive pulmonary diseaseIntern Med201655322322926831014
  • DuyarSSPlatelet to Lymphocyte Ratio as a Novel Prognostic Marker in Male Patients with Chronic Obstructive Pulmonary DiseaseInt J Respir Pulm Med201631043
  • van de GeijnGMDenkerSMeuleman-van WaningVEvaluation of new laboratory tests to discriminate bacterial from nonbacterial chronic obstructive pulmonary disease exacerbationsInt J Lab Hematol201638661662827459873
  • LeeHUmSJKimYSAssociation of the neutrophil-to-lymphocyte ratio with lung function and exacerbations in patients with chronic obstructive pulmonary diseasePLoS One2016116e015651127258044
  • Mohamed-HusseinAAlySSAsmaaMZahranAMNeutrophil CD64 and neutrophil/lymphocyte ratio as predictors of hospital outcome in acute exacerbation COPDIJASRM20172717
  • Acartürk TunçayEKarakurtZAksoyEEosinophilic and non-eosinophilic COPD patients with chronic respiratory failure: neutrophil-to-lymphocyte ratio as an exacerbation markerInt J Chron Obstruct Pulmon Dis2017123361337029200843
  • TanrıverdiHÖrnekTErboyFComparison of diagnostic values of procalcitonin, C-reactive protein and blood neutrophil/lymphocyte ratio levels in predicting bacterial infection in hospitalized patients with acute exacerbations of COPDWien Klin Wochenschr201512719–2075676325586444
  • RahimiradSGhaffaryMRRahimiradMHRashidiFAssociation between admission neutrophil to lymphocyte ratio and outcomes in patients with acute exacerbation of chronic obstructive pulmonary diseaseTuberk Toraks2017651253128621246
  • YaoCLiuXTangZPrognostic role of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio for hospital mortality in patients with AECOPDInt J Chron Obstruct Pulmon Dis2017122285229028814856
  • AngelisNPorpodisKZarogoulidisPAirway inflammation in chronic obstructive pulmonary diseaseJ Thorac Dis20146Suppl 1S167S17224672691
  • KingPTInflammation in chronic obstructive pulmonary disease and its role in cardiovascular disease and lung cancerClin Transl Med2015416826220864
  • ShaykhievRCrystalRGInnate immunity and chronic obstructive pulmonary disease: a mini-reviewGerontology201359648148924008598
  • NurwidyaFDamayantiTYunusFThe Role of Innate and Adaptive Immune Cells in the Immunopathogenesis of Chronic Obstructive Pulmonary DiseaseTuberc Respir Dis2016791513
  • VlahosRBozinovskiSRole of alveolar macrophages in chronic obstructive pulmonary diseaseFront Immunol2014543525309536
  • GiviMERedegeldFAFolkertsGMortazEDendritic cells in pathogenesis of COPDCurr Pharm Des201218162329233522390696
  • HoenderdosKCondliffeAThe neutrophil in chronic obstructive pulmonary diseaseAm J Respir Cell Mol Biol201348553153923328639
  • SzeMADimitriuPAHayashiSThe lung tissue microbiome in chronic obstructive pulmonary diseaseAm J Respir Crit Care Med2012185101073108022427533
  • MaenoTHoughtonAMQuinteroPAGrumelliSOwenCAShapiroSDCD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in miceJ Immunol2007178128090809617548647
  • JuJAn Increased Proportion of Apoptosis in CD4+ T Lymphocytes Isolated from the Peripheral Blood in Patients with Stable Chronic Obstructive Pulmonary DiseaseTuberc Respir Dis2018812132137
  • OhJYSinDDLung inflammation in COPD: why does it matter?F1000 Med Rep201242323236338
  • SuBLiuTFanHInflammatory Markers and the Risk of Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-AnalysisPLoS One2016114e015058627104349
  • DonaldsonGCSeemungalTAPatelISAirway and systemic inflammation and decline in lung function in patients with COPDChest200512841995200416236847
  • CataudellaEGiraffaCMDi MarcaSNeutrophil-To-Lymphocyte Ratio: An Emerging Marker Predicting Prognosis in Elderly Adults with Community-Acquired PneumoniaJ Am Geriatr Soc20176581796180128407209
  • IsaacVWuCYHuangCTBauneBTTsengCLMclachlanCSElevated neutrophil to lymphocyte ratio predicts mortality in medical inpatients with multiple chronic conditionsMedicine20169523e383227281085
  • YuYQianLCuiJValue of neutrophil-to-lymphocyte ratio for predicting lung cancer prognosis: a meta-analysis of 7,219 patientsMol Clin Oncol20177349850628811903
  • de MoraesMRda CostaACCorrêaKSJunqueira-KipnisAPRabahiMFInterleukin-6 and interleukin-8 blood levels’ poor association with the severity and clinical profile of ex-smokers with COPDInt J Chron Obstruct Pulmon Dis2014973574325114519
  • Torres-RamosYDGarcía-GuillenMLOlivares-CorichiIMHicksJJCorrelation of Plasma Protein Carbonyls and C-Reactive Protein with GOLD Stage Progression in COPD PatientsOpen Respir Med J200931616619461898
  • AgustíAEdwardsLDRennardSIPersistent systemic inflammation is associated with poor clinical outcomes in COPD: a novel phenotypePLoS One201275e3748322624038
  • GallegoMPomaresXCapillaSC-reactive protein in outpatients with acute exacerbation of COPD: its relationship with microbial etiology and severityInt J Chron Obstruct Pulmon Dis2016112633264027799762
  • Emami ArdestaniMZaerinORole of Serum Interleukin 6, Albumin and C-Reactive Protein in COPD PatientsTanaffos201514213414026528368
  • HurstJRVestboJAnzuetoAEvaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary diseaseN Engl J Med2010363121128113820843247
  • KoutsokeraAKostikasKNicodLPFittingJWPulmonary biomarkers in COPD exacerbations: a systematic reviewRespir Res201314111124143945
  • KolsumUDonaldsonGCSinghRBlood and sputum eosinophils in COPD; relationship with bacterial loadRespir Res20171818828482840
  • MathanrajSVysakKYuvarajanSCorrelation of serum TNF alpha level with severity of chronic obstructive pulmonary diseaseInt J Res Med Sci20175833093316
  • MeshramPLShindeSNRamrajeNNHegdeRRStudy of inflammatory markers and BODE index in chronic obstructive pulmonary diseaseLung India2018351374029319032
  • Garcia-RioFMiravitllesMSorianoJBSystemic inflammation in chronic obstructive pulmonary disease: a population-based studyRespir Res20101116320500811
  • ShafiekHOutcome Predictors of Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Role of Inflammatory BiomarkersInt J Respir Pulm Med201632047
  • LeuzziGGaleoneCTavernaFSuatoniPMorelliDPastorinoUC-reactive protein level predicts mortality in COPD: a systematic review and meta-analysisEur Respir Rev20172614316007028143876
  • KellyEOwenCAPinto-PlataVCelliBRThe role of systemic inflammatory biomarkers to predict mortality in chronic obstructive pulmonary diseaseExpert Rev Respir Med201371576423362815