Predictors of 30- and 90-Day COPD Exacerbation Readmission: A Prospective Cohort Study

References

• Oliveira CC, Lee AL, McGinley J, et al. Balance and falls in acute exacerbation of chronic obstructive pulmonary disease: a prospective study. COPD. 2017;14(5):518–525. doi:10.1080/15412555.2017.1342232
   PubMedGoogle Scholar
• Ho TW, Tsai YJ, Ruan SY, Huang CT, Lai F, Yu CJ. In-hospital and one-year mortality and their predictors in patients hospitalized for first-ever chronic obstructive pulmonary disease exacerbations: a nationwide population-based study. PLoS One. 2014;9(12):e114866. doi:10.1371/journal.pone.0114866
   PubMed Web of Science ®Google Scholar
• Soler-Cataluña JJ, Martínez-García MA, Román Sánchez P, Salcedo E, Navarro M, Ochando R. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005;60(11):925–931.
   PubMed Web of Science ®Google Scholar
• Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009;360(14):1418–1428. doi:10.1056/NEJMsa0803563
   PubMed Web of Science ®Google Scholar
• Iacobucci G. Hospital readmissions for COPD in England are rising, audit shows. BMJ. 2017;356:j557. doi:10.1136/bmj.j557
   PubMedGoogle Scholar
• Stone RAH-BJ, Lowe D, McMillan V, et al. COPD: Who Cares When It Matters Most? National Chronic Obstructive Pulmonary Disease (COPD) Audit Programme: Outcomes from the Clinical Audit of COPD Exacerbations Admitted to Acute Units in England 2014. National Supplementary Report. London: RCP; 2017. Available from: www.rcplondon.ac.uk/copd-outcomesreport2014. Accessed September 30, 2021.
   Google Scholar
• Alqahtani JS, Njoku CM, Bereznicki B, et al. Risk factors for all-cause hospital readmission following exacerbation of COPD: a systematic review and meta-analysis. Eur Respir Rev. 2020;29(156):190166. doi:10.1183/16000617.0166-2019
   PubMed Web of Science ®Google Scholar
• Hartl S, Lopez-Campos JL, Pozo-Rodriguez F, et al. Risk of death and readmission of hospital-admitted COPD exacerbations: European COPD audit. Eur Respir J. 2016;47(1):113–121. doi:10.1183/13993003.01391-2014
   PubMed Web of Science ®Google Scholar
• Alqahtani JS, Aquilina J, Bafadhel M, et al. Research priorities for exacerbations of COPD. Lancet Respir Med. 2021;9(8):824–826. doi:10.1016/S2213-2600(21)00227-7
   PubMed Web of Science ®Google Scholar
• Myers LC, Faridi MK, Hasegawa K, Hanania NA, Camargo CA. The hospital readmissions reduction program and readmissions for chronic obstructive pulmonary disease, 2006–2015. Ann Am Thorac Soc. 2019;17(4):450–456. doi:10.1513/AnnalsATS.201909-672OC
   Web of Science ®Google Scholar
• Press VG, Au DH, Bourbeau J, et al. Reducing chronic obstructive pulmonary disease hospital readmissions. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2019;16(2):161–170. doi:10.1513/AnnalsATS.201811-755WS
   PubMed Web of Science ®Google Scholar
• Nuñez A, Miravitlles M. Preventing readmissions of COPD patients: more prospective studies are needed. Eur Respir Rev. 2020;29(156):200097. doi:10.1183/16000617.0097-2020
   PubMed Web of Science ®Google Scholar
• Alqahtani J Mechanisms of COPD exacerbation recurrence; 2018. Available from: https://clinicaltrials.gov/ct2/show/NCT04024735. Accessed August 13, 2020.
   Google Scholar
• Bestall J, Paul E, Garrod R, Garnham R, Jones P, Wedzicha JJT. Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease. Thorax. 1999;54(7):581–586.
   PubMed Web of Science ®Google Scholar
• Jones PW, Harding G, Berry P, Wiklund I, Chen WH, Kline Leidy N. Development and first validation of the COPD assessment test. Eur Respir J. 2009;34(3):648. doi:10.1183/09031936.00102509
   PubMed Web of Science ®Google Scholar
• Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatrica Scandinavica. 1983;67(6):361–370.
   PubMed Web of Science ®Google Scholar
• Hilmer SN, Perera V, Mitchell S, et al. The assessment of frailty in older people in acute care. Austr J Ageing. 2009;28(4):182–188.
   PubMed Web of Science ®Google Scholar
• Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J. 2005;26(2):319–338. doi:10.1183/09031936.05.00034805
   PubMed Web of Science ®Google Scholar
• Oostveen E, MacLeod D, Lorino H, et al. The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J. 2003;22(6):1026. doi:10.1183/09031936.03.00089403
   PubMed Web of Science ®Google Scholar
• Dellacà RL, Santus P, Aliverti A, et al. Detection of expiratory flow limitation in COPD using the forced oscillation technique. Eur Respir J. 2004;23(2):232. doi:10.1183/09031936.04.00046804
   PubMed Web of Science ®Google Scholar
• Broeders ME, Molema J, Vermue NA, Folgering HT. In check dial: accuracy for Diskus and Turbuhaler. Int J Pharm. 2003;252(1–2):275–280. doi:10.1016/S0378-5173(02)00650-6
   PubMedGoogle Scholar
• Chrystyn H. Is inhalation rate important for a dry powder inhaler? Using the in-check dial to identify these rates. Respir Med. 2003;97(2):181–187. doi:10.1053/rmed.2003.1351
   PubMed Web of Science ®Google Scholar
• Peduzzi P, Concato J, Feinstein AR, Holford TR. Importance of events per independent variable in proportional hazards regression analysis. II. Accuracy and precision of regression estimates. J Clin Epidemiol. 1995;48(12):1503–1510. doi:10.1016/0895-4356(95)00048-8
   PubMed Web of Science ®Google Scholar
• Peduzzi P, Concato J, Kemper E, Holford TR, Feinstein AR. A simulation study of the number of events per variable in logistic regression analysis. J Clin Epidemiol. 1996;49(12):1373–1379. doi:10.1016/S0895-4356(96)00236-3
   PubMed Web of Science ®Google Scholar
• Loh CH, Peters SP, Lovings TM, Ohar JA. Suboptimal inspiratory flow rates are associated with chronic obstructive pulmonary disease and all-cause readmissions. Ann Am Thorac Soc. 2017;14(8):1305–1311. doi:10.1513/AnnalsATS.201611-903OC
   PubMed Web of Science ®Google Scholar
• Sharma G, Mahler DA, Mayorga VM, Deering KL, Harshaw O, Ganapathy V. Prevalence of low peak inspiratory flow rate at discharge in patients hospitalized for COPD exacerbation. Chronic Obstruct Pul Dis. 2017;4(3):217–224. doi:10.15326/jcopdf.4.3.2017.0183
   PubMed Web of Science ®Google Scholar
• Njoku CM, Alqahtani JS, Wimmer BC, et al. Risk factors and associated outcomes of hospital readmission in COPD: a systematic review. Respir Med. 2020;173:105988. doi:10.1016/j.rmed.2020.105988
   PubMed Web of Science ®Google Scholar
• Wedzicha JA, Wilkinson T. Impact of chronic obstructive pulmonary disease exacerbations on patients and payers. Proc Am Thorac Soc. 2006;3(3):218–221. doi:10.1513/pats.200510-114SF
   PubMedGoogle Scholar
• Andersson F, Borg S, Jansson SA, et al. The costs of exacerbations in chronic obstructive pulmonary disease (COPD). Respir Med. 2002;96(9):700–708. doi:10.1053/rmed.2002.1334
   PubMed Web of Science ®Google Scholar
• Soler-Cataluña JJ, Martínez-García MÁ, Román Sánchez P, Salcedo E, Navarro M, Ochando R. Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax. 2005;60(11):925.
   PubMed Web of Science ®Google Scholar
• Wilkinson TMA, Donaldson GC, Hurst JR, Seemungal TAR, Wedzicha JA. Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2004;169(12):1298–1303. doi:10.1164/rccm.200310-1443OC
   PubMed Web of Science ®Google Scholar
• Bernabeu-Mora R, García-Guillamón G, Valera-Novella E, Giménez-Giménez LM, Escolar-Reina P, Medina-Mirapeix F. Frailty is a predictive factor of readmission within 90 days of hospitalization for acute exacerbations of chronic obstructive pulmonary disease: a longitudinal study. Ther Adv Respir Dis. 2017;11(10):383–392. doi:10.1177/1753465817726314
   PubMed Web of Science ®Google Scholar
• Iyer AS, Bhatt SP, Garner JJ, et al. Depression is associated with readmission for acute exacerbation of chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2016;13(2):197–203.
   PubMed Web of Science ®Google Scholar
• Light RW, Merrill EJ, Despars JA, Gordon GH, Mutalipassi LR. Prevalence of depression and anxiety in patients with COPD. Relationship to functional capacity. Chest. 1985;87(1):35–38. doi:10.1378/chest.87.1.35
   PubMed Web of Science ®Google Scholar
• Usmani ZA, Carson KV, Cheng JN, Esterman AJ, Smith BJ. Pharmacological interventions for the treatment of anxiety disorders in chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2011;11:Cd008483.
   Google Scholar
• Walker PP, Pompilio PP, Zanaboni P, et al. Telemonitoring in chronic obstructive pulmonary disease (chromed) a randomized clinical trial. Am J Respir Crit Care Med. 2018;198(5):620–628. doi:10.1164/rccm.201712-2404OC
   PubMed Web of Science ®Google Scholar