Circulating Complement C1q as a Novel Biomarker is Associated with the Occurrence and Development of COPD

References

• Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease; 2021. Available from: https://goldcopd.org/. Accessed Nov 22, 2020.
   Google Scholar
• Barnes PJ, Burney PG, Silverman EK, et al. Chronic obstructive pulmonary disease. Nat Rev Dis Primers. 2015;1:15076. doi:10.1038/nrdp.2015.76
   PubMed Web of Science ®Google Scholar
• Cosio MG, Saetta M, Agusti A. Immunologic aspects of chronic obstructive pulmonary disease. N Engl J Med. 2009;360(23):2445–2454. doi:10.1056/NEJMra0804752
   PubMed Web of Science ®Google Scholar
• Brusselle GG, Joos GF, Bracke KR. New insights into the immunology of chronic obstructive pulmonary disease. Lancet. 2011;378(9795):1015–1026. doi:10.1016/S0140-6736(11)60988-4
   PubMed Web of Science ®Google Scholar
• Hsu AT, Gottschalk TA, Tsantikos E, Hibbs ML. The role of innate lymphoid cells in chronic respiratory diseases. Front Immunol. 2021;12:733324. doi:10.3389/fimmu.2021.733324
   PubMed Web of Science ®Google Scholar
• Lourenco JD, Ito JT, Martins MA, Tiberio I, Lopes F. Th17/Treg imbalance in chronic obstructive pulmonary disease: clinical and experimental evidence. Front Immunol. 2021;12:804919. doi:10.3389/fimmu.2021.804919
   PubMed Web of Science ®Google Scholar
• Halper-Stromberg E, Yun JH, Parker MM, et al. Systemic markers of adaptive and innate immunity are associated with chronic obstructive pulmonary disease severity and spirometric disease progression. Am J Respir Cell Mol Biol. 2018;58(4):500–509. doi:10.1165/rcmb.2017-0373OC
   PubMed Web of Science ®Google Scholar
• Urbanowicz RA, Lamb JR, Todd I, Corne JM, Fairclough LC. Altered effector function of peripheral cytotoxic cells in COPD. Respir Res. 2009;10:53. doi:10.1186/1465-9921-10-53
   PubMed Web of Science ®Google Scholar
• Tang Y, Li X, Wang M, et al. Increased numbers of NK cells, NKT-like cells, and NK inhibitory receptors in peripheral blood of patients with chronic obstructive pulmonary disease. Clin Dev Immunol. 2013;2013:721782. doi:10.1155/2013/721782
   PubMedGoogle Scholar
• Zhou JS, Li ZY, Xu XC, et al. Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice. Eur Respir J. 2020;56(3):2000404. doi:10.1183/13993003.00404-2020
   PubMed Web of Science ®Google Scholar
• Kishore U, Reid KB. C1q: structure, function, and receptors. Immunopharmacology. 2000;49(1–2):159–170. doi:10.1016/S0162-3109(00)80301-X
   PubMed Web of Science ®Google Scholar
• Sharma M, Vignesh P, Tiewsoh K, Rawat A. Revisiting the complement system in systemic lupus erythematosus. Expert Rev Clin Immunol. 2020;16(4):397–408. doi:10.1080/1744666X.2020.1745063
   PubMed Web of Science ®Google Scholar
• Liaskos C, Rentouli S, Simopoulou T, et al. Anti-C1q autoantibodies are frequently detected in patients with systemic sclerosis associated with pulmonary fibrosis. Br J Dermatol. 2019;181(1):138–146. doi:10.1111/bjd.17886
   PubMed Web of Science ®Google Scholar
• Mangogna A, Agostinis C, Bonazza D, et al. Is the complement protein C1q a pro- or anti-tumorigenic factor? Bioinformatics analysis involving human carcinomas. Front Immunol. 2019;10:865. doi:10.3389/fimmu.2019.00865
   PubMed Web of Science ®Google Scholar
• Lubbers R, Sutherland JS, Goletti D, et al. Complement component C1q as serum biomarker to detect active tuberculosis. Front Immunol. 2018;9:2427. doi:10.3389/fimmu.2018.02427
   PubMed Web of Science ®Google Scholar
• Yuan X, Chang CY, You R, et al. Cigarette smoke-induced reduction of C1q promotes emphysema. JCI Insight. 2019;5. doi:10.1172/jci.insight.124317
   PubMed Web of Science ®Google Scholar
• Fedorov A, Beichel R, Kalpathy-Cramer J, et al. 3D slicer as an image computing platform for the quantitative imaging network. Magn Reson Imaging. 2012;30(9):1323–1341. doi:10.1016/j.mri.2012.05.001
   PubMed Web of Science ®Google Scholar
• Ohara T, Hirai T, Muro S, et al. Relationship between pulmonary emphysema and osteoporosis assessed by CT in patients with COPD. Chest. 2008;134(6):1244–1249. doi:10.1378/chest.07-3054
   PubMed Web of Science ®Google Scholar
• Anthonisen NR, Manfreda J, Warren CP, Hershfield ES, Harding GK, Nelson NA. Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease. Ann Intern Med. 1987;106(2):196–204. doi:10.7326/0003-4819-106-2-196
   PubMed Web of Science ®Google Scholar
• Lynch DA, Austin JH, Hogg JC, et al. CT-definable subtypes of chronic obstructive pulmonary disease: a statement of the Fleischner society. Radiology. 2015;277(1):192–205. doi:10.1148/radiol.2015141579
   PubMed Web of Science ®Google Scholar
• Hersh CP, Washko GR, Estepar RS, et al. Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD. Respir Res. 2013;14:42. doi:10.1186/1465-9921-14-42
   PubMed Web of Science ®Google Scholar
• Boueiz A, Chang Y, Cho MH, et al. Lobar emphysema distribution is associated with 5-year radiological disease progression. Chest. 2018;153(1):65–76. doi:10.1016/j.chest.2017.09.022
   PubMed Web of Science ®Google Scholar
• Sapey E, Stockley JA, Greenwood H, et al. Behavioral and structural differences in migrating peripheral neutrophils from patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2011;183(9):1176–1186. doi:10.1164/rccm.201008-1285OC
   PubMed Web of Science ®Google Scholar
• Wang L, Yang H, Gu W. Value of erythrocyte sedimentation rate and serum epo levels in evaluating the condition and prognosis of COPD in the elderly. Pak J Pharm Sci. 2021;34(1):435–439.
   PubMed Web of Science ®Google Scholar
• Zhang M, Zhang J, Zhang Q, et al. D-dimer as a potential biomarker for the progression of COPD. Clin Chim Acta. 2016;455:55–59. doi:10.1016/j.cca.2016.01.024
   PubMed Web of Science ®Google Scholar
• Sahin F, Kosar AF, Aslan AF, Yigitbas B, Uslu B. Serum biomarkers in patients with stable and acute exacerbation of chronic obstructive pulmonary disease: a comparative study. J Med Biochem. 2019;38(4):503–511. doi:10.2478/jomb-2018-0050
   PubMed Web of Science ®Google Scholar
• Suissa S, Dell’Aniello S, Ernst P. Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality. Thorax. 2012;67(11):957–963. doi:10.1136/thoraxjnl-2011-201518
   PubMed Web of Science ®Google Scholar
• Sadatsafavi M, Xie H, Etminan M, Johnson K, FitzGerald JM. Canadian respiratory research N. The association between previous and future severe exacerbations of chronic obstructive pulmonary disease: updating the literature using robust statistical methodology. PLoS One. 2018;13(1):e0191243. doi:10.1371/journal.pone.0191243
   PubMed Web of Science ®Google Scholar