References
- HowladerNANooneAMKrapchoMNational Cancer InstituteSEER cancer statistics review, 1975–2009 (vintage 2009 populations)2011 [Updated August 20, 2012]. Available from: http://seer.cancer.gov/csr/1975_2009_pops09/index.htmlAccessed November 19, 2012
- BurgerPCVogelFSGreenSBStrikeTAGlioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implicationsCancer1985565110611112990664
- Central Brain Tumor Registry of the United StatesCBTRUS Statistical Report: Primary Brain and Central Nervous System Diagnosed in the United States in 2004–2007Hinsdale, ILCentral Brain Tumor Registry of the United States2011 Available from: http://www.cbtrus.org/2011-NPCR-SEER/WEB-0407-Report-3-3-2011.pdfAccessed November 19, 2012
- FewerDWilsonCBBoldreyEBEnotKJPowellMRThe chemotherapy of brain tumors. Clinical experience with carmustine (BCNU) and vincristineJAMA197222255495524343318
- WilsonCBGutinPBoldreyEBDraftsDLevinVAEnotKJSingle-agent chemotherapy of brain tumors. A five-year reviewArch Neurol19763311739744185991
- ChangCHHortonJSchoenfeldDComparison of postoperative radiotherapy and combined postoperative radiotherapy and chemotherapy in the multidisciplinary management of malignant gliomas. A joint Radiation Therapy Oncology Group and Eastern Cooperative Oncology Group studyCancer198352699710076349785
- SoleroCLMonfardiniSBrambillaCControlled study with BCNU vs CCNU as adjuvant chemotherapy following surgery plus radiotherapy for glioblastoma multiformeCancer Clin Trials1979214348229983
- StevensMFNewlandsESFrom triazines and triazenes to temozolomideEur J Cancer199329A7104510478499135
- NewlandsESStevensMFWedgeSRWheelhouseRTBrockCTemozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trialsCancer Treat Rev199723135619189180
- SchwartzbaumJAFisherJLAldapeKDWrenschMEpidemiology and molecular pathology of gliomaNat Clin Pract Neurol20062949450316932614
- OhgakiHDessenPJourdeBGenetic pathways to glioblastoma: a population-based studyCancer Res200464196892689915466178
- National Toxicology ProgramFinal report on carcinogens background document for formaldehydeRep Carcinog Backgr Doc201010-5981i-512
- DeltourIAuvinenAFeychtingMMobile phone use and incidence of glioma in the Nordic countries1979–2008: consistency checkEpidemiology201223230130722249239
- LittleMPRajaramanPCurtisREMobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United StatesBMJ2012344e114722403263
- SampsonJHMitchellDAIs cytomegalovirus a therapeutic target in glioblastoma?Clin Cancer Res201117144619462121632859
- NegliaJPMeadowsATRobisonLLSecond neoplasms after acute lymphoblastic leukemia in childhoodN Engl J Med199132519133013361922234
- WatanabeKSatoKBiernatWIncidence and timing of p53 mutations during astrocytoma progression in patients with multiple biopsiesClin Cancer Res1997345235309815715
- HegiMEDiserensACGorliaTMGMT gene silencing and benefit from temozolomide in glioblastomaN Engl J Med200535210997100315758010
- NoushmehrHWeisenbergerDJDiefesKIdentification of a CpG island methylator phenotype that defines a distinct subgroup of gliomaCancer Cell201017551052220399149
- TentoriLOrlandoLLacalPMInhibition of O6-alkylguanine DNA-alkyltransferase or poly(ADP-ribose) polymerase increases susceptibility of leukemic cells to apoptosis induced by temozolomideMol Pharmacol19975222492589271347
- RoosWPBatistaLFNaumannSCApoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanineOncogene200726218619716819506
- HammondLAEckardtJRBakerSDPhase I and pharmacokinetic study of temozolomide on a daily-for-5-days schedule in patients with advanced solid malignanciesJ Clin Oncol19991782604261310561328
- ParkDMShahDDEgorinMJBeumerJHDisposition of temozolomide in a patient with glioblastoma multiforme after gastric bypass surgeryJ Neurooncol200993227928319125222
- GanderMLeyvrazSDecosterdLSequential administration of temozolomide and fotemustine: depletion of O6-alkyl guanine-DNA transferase in blood lymphocytes and in tumoursAnn Oncol199910783183810470431
- OstermannSCsajkaCBuclinTPlasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patientsClin Cancer Res200410113728373615173079
- BakerSDWirthMStatkevichPAbsorption, metabolism, and excretion of 14C-temozolomide following oral administration to patients with advanced cancerClin Cancer Res19995230931710037179
- NewlandsESBlackledgeGRSlackJAPhase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)Br J Cancer19926522872911739631
- O’ReillySMNewlandsESGlaserMGTemozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumoursEur J Cancer199329A79409428499146
- BowerMNewlandsESBleehenNMMulticentre CRC phase II trial of temozolomide in recurrent or progressive high-grade gliomaCancer Chemother Pharmacol19974064844889332462
- YungWKAlbrightREOlsonJA phase II study of temozolomide vs procarbazine in patients with glioblastoma multiforme at first relapseBr J Cancer200083558859310944597
- BrockCSNewlandsESWedgeSRPhase I trial of temozolomide using an extended continuous oral scheduleCancer Res19985819436343679766665
- StuppRDietrichPYOstermann KraljevicSPromising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomideJ Clin Oncol20022051375138211870182
- StuppRMasonWPvan den BentMJRadiotherapy plus concomitant and adjuvant temozolomide for glioblastomaN Engl J Med20053521098799615758009
- NelsonDFDiener-WestMHortonJChangCHSchoenfeldDNelsonJSCombined modality approach to treatment of malignant gliomas – re-evaluation of RTOG 7401/ECOG 1374 with long-term follow-up: a joint study of the Radiation Therapy Oncology Group and the Eastern Cooperative Oncology GroupNCI Monogr198862792843281031
- TaphoornMJStuppRCoensCHealth-related quality of life in patients with glioblastoma: a randomised controlled trialLancet Oncol200561293794416321761
- WickWPlattenMWellerMNew (alternative) temozolomide regimens for the treatment of gliomaNeuro Oncol2009111697918772354
- GilbertMRWangMAldapeKDRTOG 0525: a randomized phase III trial comparing standard adjuvant temozolomide (TMZ) with a dose-dense (dd) schedule in newly diagnosed glioblastoma (GBM) [abstract]J Clin Oncol2011292006
- Temodar® [prescribing information]Whitehouse Station, NJMerck and Co, Inc2012
- OhJKutasGJDaveyPMorrisonMPerryJRAplastic anemia with concurrent temozolomide treatment in a patient with glioblastoma multiformeCurr Oncol201017412412620697524
- SarmaNStevens–Johnson syndrome and toxic epidermal necrolysis overlap due to oral temozolomide and cranial radiotherapyAm J Clin Dermatol200910426426719489660
- IwamotoFMReinerASPanageasKSElkinEBAbreyLEPatterns of care in elderly glioblastoma patientsAnn Neurol200864662863419107984
- RepettoLGreater risks of chemotherapy toxicity in elderly patients with cancerJ Support Oncol200314 Suppl 2182415346996
- HottingerAFDeAngelisLMYahalomJAbreyLESalvage whole brain radiotherapy for recurrent or refractory primary CNS lymphomaNeurology200769111178118217846417
- GavrilovicITHormigoAYahalomJDeAngelisLMAbreyLELong-term follow-up of high-dose methotrexate-based therapy with and without whole brain irradiation for newly diagnosed primary CNS lymphomaJ Clin Oncol200624284570457417008697
- WickWPlattenMMeisnerCTemozolomide chemotherapy alone versus radiotherapy alone for malignant astrocytoma in the elderly: the NOA-08 randomised, phase 3 trialLancet Oncol201213770771522578793
- MalmstromAGronbergBHMarosiCTemozolomide versus standard 6-week radiotherapy versus hypofractionated radiotherapy in patients older than 60 years with glioblastoma: the Nordic randomised, phase 3 trialLancet Oncol201213991692622877848
- De VosFYGijtenbeekJMBleeker-RoversCPvan HerpenCMPneumocystis jirovecii pneumonia prophylaxis during temozolomide treatment for high-grade gliomasCrit Rev Oncol Hematol8252012
- HayashiHSaitoYKokuhoNFatal pneumonia associated with temozolomide therapy in patients with malignant gliomaJpn J Clin Oncol201242763263622525211
- JickHAdverse reactions to trimethoprim-sulfamethoxazole in hospitalized patientsRev Infect Dis1982424264286981160
- SmilackJDTrimethoprim-sulfamethoxazoleMayo Clin Proc199974773073410405706
- HegiMELiuLHermanJGCorrelation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activityJ Clin Oncol200826254189419918757334
- UnoMOba-ShinjoSMCamargoAACorrelation of MGMT promoter methylation status with gene and protein expression levels in glioblastomaClinics (Sao Paulo)201166101747175522012047
- RodriguezFJThibodeauSNJenkinsRBMGMT immunohistochemical expression and promoter methylation in human glioblastomaAppl Immunohistochem Mol Morphol2008161596518091318
- KishidaYNatsumeATodaHCorrelation between quantified promoter methylation and enzymatic activity of O6-methylguanine-DNA methyltransferase in glioblastomasTumour Biol201233237338122274924
- GeorgiadisPPolychronakiNKyrtopoulosSAProgress in high-throughput assays of MGMT and APE1 activities in cell extractsMutat Res20127361–2253222609488
- KimYSKimSHChoJMGMT gene promoter methylation as a potent prognostic factor in glioblastoma treated with temozolomide-based chemoradiotherapy: a single-institution studyInt J Radiat Oncol Biol Phys201284366166722414280
- MinnitiGSalvatiMArcellaACorrelation between O6-methylguanine-DNA methyltransferase and survival in elderly patients with glioblastoma treated with radiotherapy plus concomitant and adjuvant temozolomideJ Neurooncol2011102231131620686820
- VlassenbroeckICalificeSDiserensACValidation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in gliomaJ Mol Diagn200810433233718556773
- HavikABBrandalPHonneHMGMT promoter methylation in gliomas-assessment by pyrosequencing and quantitative methylation-specific PCRJ Transl Med2012103622390413
- ChristiansAHartmannCBennerAPrognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastomaPLoS One201273e3344922428052
- BrandesAAFranceschiETosoniAMGMT promoter methylation status can predict the incidence and outcome of pseudoprogression after concomitant radiochemotherapy in newly diagnosed glioblastoma patientsJ Clin Oncol200826132192219718445844
- PerryJRBelangerKMasonWPPhase II trial of continuous dose-intense temozolomide in recurrent malignant glioma: RESCUE studyJ Clin Oncol201028122051205720308655
- RecinosVRTylerBMBekelisKCombination of intracranial temozolomide with intracranial carmustine improves survival when compared with either treatment alone in a rodent glioma modelNeurosurgery201066353053720173548
- DongJZhouGTangDLocal delivery of slow-releasing temozolomide microspheres inhibits intracranial xenograft glioma growthJ Cancer Res Clin Oncol2012138122079208422825126
- PatilRPortilla-AriasJDingHTemozolomide delivery to tumor cells by a multifunctional nano vehicle based on poly(β-L-malic acid)Pharm Res201027112317232920387095
- FujitaMLeeBSKhazenzonNMBrain tumor tandem targeting using a combination of monoclonal antibodies attached to biopoly(β-L-malic acid)J Control Release2007122335636317630012
- JainAChasooGSinghSKSaxenaAKJainSKTransferrin-appended PEGylated nanoparticles for temozolomide delivery to brain: in vitro characterisationJ Microencapsul2011281212821171813
- FriedmanHSKokkinakisDMPludaJPhase I trial of O6-benzylguanine for patients undergoing surgery for malignant gliomaJ Clin Oncol19981611357035759817277
- QuinnJAJiangSXReardonDAPhase II trial of temozolomide plus O6-benzylguanine in adults with recurrent, temozolomide-resistant malignant gliomaJ Clin Oncol20092781262126719204199
- AdairJEBeardBCTrobridgeGDExtended survival of glioblastoma patients after chemoprotective HSC gene therapySci Transl Med20124133133ra57