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Original Research

Rosmarinic acid ameliorates hyperglycemia and insulin sensitivity in diabetic rats, potentially by modulating the expression of PEPCK and GLUT4

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Pages 2193-2202 | Published online: 07 Jul 2016

References

  • YehGYEisenbergDMKaptchukTJPhillipsRSSystematic review of herbs and dietary supplements for glycemic control in diabetesDiabetes Care20032641277129412663610
  • PetersenMRosmarinic acid: new aspectsPhytochem Rev2013121207227
  • AzevedoMFLimaCFFernandes-FerreiraMAlmeidaMJWilsonJMPereira-WilsonCRosmarinic acid, major phenolic constituent of Greek sage herbal tea, modulates rat intestinal SGLT1 levels with effects on blood glucoseMol Nutr Food Res201155Suppl 1S15S2521433280
  • JayanthyGSubramanianSRosmarinic acid, a polyphenol, ameliorates hyperglycemia by regulating the key enzymes of carbohydrate metabolism in high fat diet – STZ induced experimental diabetes mellitusBiomed Prev Nutr201443431437
  • SotnikovaROkruhlicovaLVlkovicovaJRosmarinic acid administration attenuates diabetes-induced vascular dysfunction of the rat aortaJ Pharm Pharmacol201365571372323600389
  • FarzadiLKhakiAGhasemzadehAOuladsahebmadarekEGhadamkheirEEffect of rosmarinic acid on sexual behavior in diabetic male ratsAfr J Pharm Pharmacol201151619061910
  • TavafiMAhmadvandHKhalatbariATamjidipoorARosmarinic acid ameliorates diabetic nephropathy in uninephrectomized diabetic ratsIran J Basic Med Sci2011143275283
  • JiangWLXuYZhangSPHouJZhuHBEffect of rosmarinic acid on experimental diabetic nephropathyBasic Clin Pharmacol Toxicol2012110439039522053730
  • LuanHKanZXuYLvCJiangWRosmarinic acid protects against experimental diabetes with cerebral ischemia: relation to inflammation responseJ Neuroinflammation2013102823414442
  • HasaneinPMohammad ZaheriLEffects of rosmarinic acid on an experimental model of painful diabetic neuropathy in ratsPharm Biol201452111398140225026351
  • MushtaqNSchmatzRPereiraLBRosmarinic acid prevents lipid peroxidation and increase in acetylcholinesterase activity in brain of streptozotocin-induced diabetic ratsCell Biochem Funct201432328729324301255
  • GovindarajJSorimuthu PillaiSRosmarinic acid modulates the antioxidant status and protects pancreatic tissues from glucolipotoxicity mediated oxidative stress in high-fat diet: streptozotocin-induced diabetic ratsMol Cell Biochem20154041–214315925735949
  • MatthewsDRHoskerJPRudenskiASNaylorBATreacherDFTurnerRCHomeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in manDiabetologia19852874124193899825
  • RuntuweneJAmitaniHAmitaniMAsakawaAChengKCInuiAHydrogen-water enhances 5-fluorouracil-induced inhibition of colon cancerPeer J20153e85925870767
  • BeardsallKYuenKWilliamsRDungerDApplied physiology of glucose controlCurr Paediatr2006166434438
  • WilcoxGInsulin and insulin resistanceClin Biochem Rev2005262193916278749
  • PetersenMSimmondsMSRosmarinic acidPhytochemistry200362212112512482446
  • LaiXJZhangLLiJSComparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in ratsFitoterapia201182688388821575691
  • NakazawaTOhsawaKMetabolism of rosmarinic acid in ratsJ Nat Prod19986189939969722482
  • GiaccoFBrownleeMOxidative stress and diabetic complicationsCirc Res201010791058107021030723
  • BradleyRObergEBCalabreseCStandishLJAlgorithm for complementary and alternative medicine practice and research in type 2 diabetesJ Altern Complement Med200713115917517309390
  • FadelOEl KiratKMorandatSThe natural antioxidant rosmarinic acid spontaneously penetrates membranes to inhibit lipid peroxidation in situBiochim Biophys Acta20111808122973298021864504
  • ZhuFAsadaTSatoAKoiYNishiwakiHTamuraHRosmarinic acid extract for antioxidant, antiallergic, and alpha-glucosidase inhibitory activities, isolated by supramolecular technique and solvent extraction from perilla leavesJ Agric Food Chem201462488589224400891
  • LucariniRBernardesWAFerreiraDSIn vivo analgesic and anti-inflammatory activities of Rosmarinus officinalis aqueous extracts, rosmarinic acid and its acetyl ester derivativePharm Biol20135191087109023738822
  • KarthikkumarVSivagamiGVinothkumarRRajkumarDNaliniNModulatory efficacy of rosmarinic acid on premalignant lesions and antioxidant status in 1,2-dimethylhydrazine induced rat colon carcinogenesisEnviron Toxicol Pharmacol201234394995822960260
  • PereiraPTyscaDOliveiraPda Silva BrumLFPicadaJNArdenghiPNeurobehavioral and genotoxic aspects of rosmarinic acidPharmacol Res200552319920316026713
  • TicliFKHageLICambraiaRSRosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interactionToxicon200546331832715992846
  • AiroldiCSironiEDiasCNatural compounds against Alzheimer’s disease: molecular recognition of Aβ1-42 peptide by Salvia sclareoides extract and its major component, rosmarinic acid, as investigated by NMRChem Asian J20138359660223303581
  • SwarupVGhoshJGhoshSSaxenaABasuAAntiviral and anti-inflammatory effects of rosmarinic acid in an experimental murine model of Japanese encephalitisAntimicrob Agents Chemother20075193367337017576830
  • WangJPanXHanYGuoDGuoQLiRRosmarinic acid from eelgrass shows nematicidal and antibacterial activities against pine wood nematode and its carrying bacteriaMar Drugs201210122729274023201594
  • TakanoHOsakabeNSanbongiCExtract of perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humansExp Biol Med (Maywood)2004229324725414988517
  • HuGWallsRSBassDThe Chinese herbal formulation biminne in management of perennial allergic rhinitis: a randomized, double-blind, placebo-controlled, 12-week clinical trialAnn Allergy Asthma Immunol200288547848712027069
  • SrinivasanKViswanadBAsratLKaulCLRamaraoPCombination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screeningPharmacol Res200552431332015979893
  • KingAJThe use of animal models in diabetes researchBr J Pharmacol2012166387789422352879
  • SrinivasanKRamaraoPAnimal models in type 2 diabetes research: an overviewIndian J Med Res2007125345147217496368
  • WinzellMSAhrénBThe high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetesDiabetes200453Suppl 3S215S21915561913
  • CachoJSevillanoJde CastroJHerreraERamosMPValidation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley ratsAm J Physiol Endocrinol Metab20082955E1269E127618796548
  • WallaceTMLevyJCMatthewsDRUse and abuse of HOMA modelingDiabetes Care20042761487149515161807
  • NordlieRCFosterJDLangeAJRegulation of glucose production by the liverAnnu Rev Nutr19991937940610448530
  • SurwitRSKuhnCMCochraneCMcCubbinJAFeinglosMNDiet-induced type II diabetes in C57BL/6J miceDiabetes1988379116311673044882
  • Vidal-PuigAO’RahillySMetabolism. Controlling the glucose factoryNature2001413685212512611557965
  • ShaoJQiaoLJanssenRCPagliassottiMFriedmanJEChronic hyperglycemia enhances PEPCK gene expression and hepatocellular glucose production via elevated liver activating protein/liver inhibitory protein ratioDiabetes200554497698415793235
  • QuinnPGYeagleyDInsulin regulation of PEPCK gene expression: a model for rapid and reversible modulationCurr Drug Targets Immune Endocr Metabol Disord20055442343716375695
  • ScottDKO’DohertyRMStaffordJMNewgardCBGrannerDKThe repression of hormone-activated PEPCK gene expression by glucose is insulin-independent but requires glucose metabolismJ Biol Chem19982733724145241519727036
  • TremblayFLavigneCJacquesHMaretteADefective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activitiesDiabetes20015081901191011473054
  • MaretteADimitrakoudisDShiQRodgersCDKlipAVranicMGlucose rapidly decreases plasma membrane GLUT4 content in rat skeletal muscleEndocrine1999101131810403566
  • RichterEAHargreavesMExercise, GLUT4, and skeletal muscle glucose uptakePhysiol Rev2013933993101723899560
  • GulatiVHardingIHPalomboEAEnzyme inhibitory and antioxidant activities of traditional medicinal plants: potential application in the management of hyperglycemiaBMC Complement Altern Med2012127722713130
  • ShoriABScreening of antidiabetic and antioxidant activities of medicinal plantsJ Integr Med201513529730526343100
  • BabaSOsakabeNNatsumeMAbsorption, metabolism, degradation and urinary excretion of rosmarinic acid after intake of perilla frutescens extract in humansEur J Nutr20054411915309457
  • OsakabeNTakanoHSanbongiCAnti-inflammatory and anti-allergic effect of rosmarinic acid (RA); inhibition of seasonal allergic rhinoconjunctivitis (SAR) and its mechanismBiofactors2004211–412713115630183
  • OsakabeNYasudaANatsumeMRosmarinic acid, a major polyphenolic component of perilla frutescens, reduces lipopolysaccharide (LPS)-induced liver injury in d-galactosamine (d-GalN)-sensitized miceFree Radic Biol Med200233679880612208367
  • ZouZWXuLNTianJYAntithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen)Yao Xue Xue Bao1993284241245 Chinese8213164
  • MakinoTOnoTLiuNNakamuraTMusoEHondaGSuppressive effects of rosmarinic acid on mesangioproliferative glomerulonephritis in ratsNephron200292489890412399637