References
- PickeringGLoriotMALibertFEschalierABeaunePDubrayCAcetaminophen: first evidence of a central serotonergic mechanism of action in humansClin Pharmacol Ther200679437137816580905
- PickeringGEstèveVLoriotMAEschalierADubrayCAcetaminophen reinforces descending inhibitory pain pathwaysClin Pharmacol Ther2008841475117957182
- AnderssonDAGentryCAlenmyrLTRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ(9)-tetrahydrocannabiorcolNat Commun2011255122109525
- HögestättEDJönssonBAErmundAConversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous systemJ Biol Chem200528036314053141215987694
- BarrièreDAMalletCBlomgrenAFatty acid amide hydrolase-dependent generation of antinociceptive drug metabolites acting on TRPV1 in the brainPLoS One201388e7069023940628
- BonnefontJDaulhacLEtienneMParacetamol recruits spinal p42/p44 MAPKs and GH/IGF-1 receptors to produce analgesia via the serotonergic systemMol Pharmacol200771240741517088403
- MalletCBarriereDAErmundATRPV(1) in brain is involved in acetaminophen-induced antinociceptionPLoS One201059e1274820862299
- MalletCDaulhacLBonnefontJEndocannabinoid and serotonergic systems are needed for acetaminophen-induced analgesiaPain2008139119020018485596
- KerckhoveNMalletCFrançoisACa(v)3.2 calcium channels: the key protagonist in the supraspinal effect of paracetamolPain2014155476477224447516
- SandriniMVitaleGRuggieriVPiniLAEffect of acute and repeated administration of paracetamol on opioidergic and serotonergic systems in ratsInflamm Res200756413914217522810
- GentryCAnderssonDABevanSTRPA1 mediates the hypothermic action of acetaminophenSci Rep201551277126227887
- AyoubSSPryceGSeedMPBoltonCFlowerRJBakerDParacetamol-induced hypothermia is independent of cannabinoids and transient receptor potential vanilloid-1 and is not mediated by AM404Drug Metab Dispos20113991689169521628499
- IshidaTSatoTIrifuneMTanakaKNakamuraNNishikawaTEffect of acetaminophen, a cyclooxygenase inhibitor, on Morris water maze task performance in miceJ Psychopharmacol200721775776717606472
- UmatheSNMannaSSUtturwarKSJainNSEndocannabinoids mediate anxiolytic-like effect of acetaminophen via CB1 receptorsProg Neuropsychopharmacol Biol Psychiatry20093371191119919580839
- MannaSSUmatheSNParacetamol potentiates the antidepressant-like and anticompulsive-like effects of fluoxetineBehav Pharmacol201526326828125340977
- VibergHErikssonPGordhTFredrikssonAParacetamol (acetaminophen) administration during neonatal brain development affects cognitive function and alters its analgesic and anxiolytic response in adult male miceToxicol Sci2014138113914724361869
- PickeringGMoustafaFMacianNPereiraBSchmidtJDubrayCA new transmucosal-buccal formulation of acetaminophen for acute traumatic pain: a non-inferiority randomised double-blind clinical trialPain Physician201518324925726000668
- PickeringGKastlerAMacianNThe brain signature of paracetamol in healthy volunteers: a double-blind randomized trialDrug Des Devel Ther2015938533862
- AndersenRACuiHIntention, action planning, and decision making in parietal-frontal circuitsNeuron200963556858319755101
- KhaniAKermaniMHesamSHaghparastAArgandoñaEGRainerGActivation of cannabinoid system in anterior cingulate cortex and orbitofrontal cortex modulates cost-benefit decision makingPsychopharmacology2015232122097211225529106
- TraceyIJohnsEThe pain matrix: reloaded or reborn as we image tonic pain using arterial spin labellingPain2010148335936020080346
- RogersRDThe roles of dopamine and serotonin in decision making: evidence from pharmacological experiments in humansNeuropsychopharmacology201136111413220881944
- GrahamGGScottKFMechanism of action of paracetamolAm J Therap2005121465515662292
- CouradeJPBesseDDelchambreCAcetaminophen distribution in the rat central nervous systemLife Sci200169121455146411531168
- PelissierTAllouiACaussadeFParacetamol exerts spinal antinociceptive effect involving an indirect interaction with 5-hydroxytryptamine 3 receptors: in vivo and in vitro evidenceJ Pharmacol Exp Ther199627818148764329
- NishizawaSBenkelfatCYoungSNDifferences between males and females in rates of serotonin synthesis in human brainProc Natl Acad Sci U S A19979410530853139144233
- DewallCNMacdonaldGWebsterGDAcetaminophen reduces social pain: behavioral and neural evidencePsychol Sci201021793193720548058
- RallJMMachSADashPKIntrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in ratsBrain Res2003968227327612663097
- TeatherLAPackardMGBazanNGPost-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidationLearn Mem200291414711917005
- HinzBChereminaOBruneKAcetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in manFASEB J200822238339017884974
- ChandrasekharanNVDaiHRoosKLCOX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expressionProc Natl Acad Sci U S A20029921139261393112242329
- GuzmánCBGrahamKAGraceLAMooreAHSex-dependent effect of cyclooxygenase-2 inhibition on mouse spatial memoryBehav Brain Res2009199235535919162088
- MarkusCROlivierBde HaanEHWhey protein rich in alpha lactalbumin increases the ratio of plasma tryptophan to the serum of the other large neutral amino acids and improves cognitive performance instress-vulnerable subjectsAm J Clin Nutr20027561051105612036812
- Blecharz-KlinKPiechalAPyrzanowskaJJoniec-MaciejakIKiliszekPWidy-TyszkiewiczEParacetamol – the outcome on neurotransmission and spatial learning in ratsBehav Brain Res201325315716423850354
- CathelAMReyesBAWangQCannabinoid modulation of alpha2 adrenergic receptor function in rodent medial prefrontal cortexEur J Neurosci20144083202321425131562
- KawauraKKarasawaJChakiSHikichiHStimulation of postsynapse adrenergic α2A receptor improves attention/cognition performance in an animal model of attention deficit hyperactivity disorderBehav Brain Res201427034935624882610
- MendigurenAPinedaJCannabinoids enhance N-methyl-D-aspartate-induced excitation of locus coeruleus neurons by CB1 receptors in rat brain slicesNeurosci Lett200436311515157983
- DeshpandeLSDeLorenzoRJAcetaminophen inhibits status epilepticus in cultured hippocampal neuronsNeuroreport2011221151821037491
- HuseboBSBallardCSandvikRNilsenOBAarslandDEfficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trialBMJ2011343d406521765198
- PickeringGMoustafaFDesbrandesSCardotJMRouxDDubrayCParacetamol and opioid pathways: a pilot randomized clinical trialFundam Clin Pharmacol201327333934522092536
- AyoubSSBottingRMGoorhaSColville-NashPRWilloughbyDABallouLRAcetaminophen-induced hypothermia in mice is mediated by a prostaglandin endoperoxide synthase 2 gene-derived proteinProc Nat Acad Sci U S A20071013011165
- MasseyTEWalkerRMMcElligottTFRaczWJAcetaminophen-induced hypothermia in mice: evidence for a central action of the parent compoundToxicology1982252–31877157399
- WalkerRMMasseyTEMcElligottTFRaczWJAcetaminophen-induced hypothermia, hepatic congestion, and modification by N-acetylcysteine in miceToxicol Appl Pharmacol19815935007268773
- KasnerSEWeinTPiriyawatPAcetaminophen for altering body temperature in acute stroke: a randomized clinical trialStroke200233113013411779901
- DippelDWJvan BredaEJvan der WorpHBEffect of paracetamol (acetaminophen) and ibuprofen on body temperature in acute ischemic stroke PISA, a phase II double-blind, randomized, placebo-controlled trial [ISRCTN98608690]BMC Cardiovasc Dis200332
- WongTStangASGanshornHCombined and alternating paracetamol and ibuprofen therapy for febrile childrenCochrane Database Syst Rev201310CD009572
- Engström RuudLWilhelmsDBEskilssonAAcetaminophen reduces lipopolysaccharide-induced fever by inhibiting cyclooxygenase-2Neuropharmacology20137112412923545161
- LeglerAMonoryKLutzBAge differences in the role of the cannabinoid type 1 receptor on glutamatergic neurons in habituation and spatial memory acquisitionLife Sci2015138576325744401