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Original Research

N-(3-hydroxymethyl-β-carboline-1-yl-ethyl- 2-yl)-l-Phe: development toward a nanoscaled antitumor drug capable of treating complicated thrombosis and inflammation

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Pages 225-239 | Published online: 17 Jan 2017

References

  • Abu SaadehFNorrisLO’TooleSTumour expression of tissue factor and tissue factor pathway inhibitor in ovarian cancer-relationship with venous thrombosis riskThromb Res20131325 627 63424094893
  • RicklesFRFalangaAMolecular basis for the relationship between thrombosis and cancerThromb Res20011026 V215 V22411516455
  • PesicMGretenFRInflammation and cancer: tissue regeneration gone awryCurr Opin Cell Biol201643 55 6127521599
  • KidaneDChaeWJCzochorJInterplay between DNA repair and inflammation, and the link to cancerCrit Rev Biochem Mol Biol2014492 116 13924410153
  • BalkwillFMantovaniACancer and inflammation: implications for pharmacology and therapeuticsClin Pharmacol Ther2010874 401 40620200512
  • BalkwillFRMantovaniACancer-related inflammation: common themes and therapeutic opportunitiesSemin Cancer Biol2012221 33 4022210179
  • MantovaniAAllavenaPSicaABalkwillFCancer-related inflammationNature20084547203 436 44418650914
  • PolekASobiczewskiWMatowicka-KarnaJP-selectin and its role in some diseasesPostepy Hig Med Dosw200963 465 470
  • HarrisonPCramerEMPlatelet alpha-granulesBlood Rev199371 52 628467233
  • MayadasTNJohnsonRCRayburnHHynesROWagnerDDLeukocyte rolling and extravasation are severely compromised in P selectin-deficient miceCell1993743 541 5547688665
  • KimYJBorsigLVarkiNMVarkiAP-selectin deficiency attenuates tumor growth and metastasisProc Natl Acad Sci U S A19989516 9325 93309689079
  • GengYTakataniTYehKHsuJWKingMRTargeting underglycosylated MUC1 for the selective capture of highly metastatic breast cancer cells under flowCell Mol Bioeng201362 148 15923805168
  • BorsigLWongRHynesROVarkiNMVarkiASynergistic effects of L- and P-selectin in facilitating tumor metastasis can involve non-mucin ligands and implicate leukocytes as enhancers of metastasisProc Natl Acad Sci U S A2002994 2193 219811854515
  • LaubliHStevensonJLVarkiAVarkiNMBorsigLL-selectin facilitation of metastasis involves temporal induction of Fut7-dependent ligands at sites of tumor cell arrestCancer Res2006663 1536 154216452210
  • LaubliHBorsigLSelectins as mediators of lung metastasisCancer Microenviron201031 97 10521209777
  • BianconeLArakiMArakiKVassalliPStamenkovicIRedirection of tumor metastasis by expression of E-selectin in vivoJ Exp Med19961832 581 5878627169
  • FerroniPRoselliMMartiniFPrognostic value of soluble P-selectin levels in colorectal cancerInt J Cancer20041113 404 40815221968
  • HaznedarogluICBenekliMOzcebeOSerum L-selectin and P-selectin levels in lymphomasHaematologia (Budap)2000301 27 3010841321
  • SchadendorfDDiehlSZuberbierTSchadendorfCHenzBMQuantitative detection of soluble adhesion molecules in sera of melanoma patients correlates with clinical stageDermatology19961922 89 938829517
  • BlannADGurneyDWadleyMBarefordDStonelakePLipGYIncreased soluble P-selectin in patients with haematological and breast cancer: a comparison with fibrinogen, plasminogen activator inhibitor and von Willebrand factorBlood Coagul Fibrinolysis2001121 43 5011229826
  • RoselliMMineoTCMartiniFSoluble selectin levels in patients with lung cancerInt J Biol Markers2002171 56 6211936588
  • Lazo-LangnerAGossGDSpaansJNRodgerMAThe effect of low-molecular-weight heparin on cancer survival. A systematic review and meta-analysis of randomized trialsJ Thromb Haemost200754 729 73717408406
  • BorsigLVlodavskyIIshai-MichaeliRTorriGVismaraESulfated hexasaccharides attenuate metastasis by inhibition of P-selectin and heparanaseNeoplasia2011135 445 45221532885
  • WuJHCuiGHZhaoMCuiCYPengSQNovel N-(3-carboxyl-9- benzylcarboline-1-yl) ethylamino acids: synthesis, anti-proliferation activity and two-step-course of intercalation with calf thymus DNAMol Biosyst2007312 855 86118000563
  • WuJHZhaoMQianKDLeeKHMorris-NatschkeSPengSQNovel N-(3-carboxyl-9-benzyl-beta-carboline-1-yl)ethylamino acids: synthesis, anti-tumor evaluation, intercalating determination, 3D QSAR analysis and docking investigationEur J Med Chem20094410 4153 416119535177
  • WuJHLiCYZhaoMWangWJWangYJPengSQA class of novel carboline intercalators: their synthesis, in vitro anti-proliferation, in vivo anti-tumor action, and 3D QSAR analysisBioorg Med Chem20101817 6220 622920692841
  • WuJHWeiLZhaoMWangYJKangGFPengSQN-[2(3-Carboxyl-9-benzyl-carboline-1-yl)ethyl-1-yl]-amino acids: correlation of spectral property with in vivo anti-tumor activityMed Chem Res2012211 116 123
  • LiSWangYJZhaoMWuJHPengSQBPIC: a novel anti-tumor lead capable of inhibiting inflammation and scavenging free radicalsBioorg Med Chem Lett2015255 1146 115025648297
  • LiSWangYWangFSmall molecule PZL318: forming fluorescent nanoparticles capable of tracing their interactions with cancer cells and activated platelets, slowing tumor growth and inhibiting thrombosisInt J Nanomedicine201510 5273 529226345234
  • XuWZhaoMWangYDesign, synthesis, and in vivo evaluations of benzyl Nω-nitro-Nα-(9H-pyrido[3,4-b]indole-3-carbonyl)-l-argininate as an apoptosis inducer capable of decreasing the serum concentration of P-selectinMed Chem Commun201679 1730 1737
  • WuJZhaoMWangYA novel lead of P-selectin inhibitor: discovery, synthesis, bioassays and action mechanismBioorg Med Chem Lett20162619 4631 463627575475
  • GanTWangYZhaoMWuJYangJPengS5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumorsDrug Des Devel Ther201610 711 721
  • KumarNKumarRNemayshVLalNLuthraPMBis((1,4-dimethyl-9H-carbazol-3-yl)methyl)amine-mediated anticancer effect triggered by sequence-specific cleavage of DNA leading to programmed cell death in the human U87 cell lineRSC Adv2016672 67925 67940
  • ReichmannMERiceSAThomasCADotyPAFurther examination of the molecular weight and size of desoxypentose nucleic acidJ Am Chem Soc19547611 3047 3053
  • NafisiSSabouryAAKeramatNNeaultJ-FTajmir-RiahiH-AStability and structural features of DNA intercalation with ethidium bromide, acridine orange and methylene blueJ Mol Struct20078271–3 35 43
  • VijayalakshmiRKanthimathiMSubramanianVNairBUInteraction of DNA with [Cr(Schiff base)(H2O)2]ClO4Biochim Biophys Acta200014752 157 16210832030
  • JinSMWangYNZhuHMNanosized aspirin-Arg-Gly-Asp-Val: delivery of aspirin to thrombus by the target carrier Arg-Gly-Asp-Val tetrapeptideACS Nano201379 7664 767323931063
  • FujitaYMieMKobatakeEConstruction of nanoscale protein particle using temperature-sensitive elastin-like peptide and polyaspartic acid chainBiomaterials20093020 3450 345719324406