Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey

References

• Lloyd-JonesDAdamsRCarnethonMHeart disease and stroke statistics – 2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics SubcommitteeCirculation2009119348048619171871
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMHongYLabartheDAmerican Heart Association Strategic Planning Task Force and Statistics CommitteeDefining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction: The American Heart Association’s Strategic Impact Goal Through 2020 and BeyondCirculation2010121458661320089546
   PubMed Web of Science ®Google Scholar
• KonesRPhillipsJHPrevention of Heart Cell DeathYuPNGoodwinJFProgress In Cardiology4Philadelphia, PALea and Febiger1975199224
   Google Scholar
• Health, United States, 2009: with special feature on medical technologyHyattsville, MDNational Center for Health Statistics2010F38
   Google Scholar
• Institute of Medicine“A population-based policy and systems change approach to prevent and control hypertension”2010Washington, DCThe National Academies Press Brief report available at: http://www.iom.edu/Reports/2010/A-Population-Based-Policy-and-Systems-Change-Approach-to-Prevent-and-Control-Hypertension/Report-Brief-Prevent-and-Control-Hypertension.aspx. [22 Febraury 2010]. Accessed March 24, 2011
   Google Scholar
• FusterVKellyBB for the Institute of Medicine (US) Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the challenges in developing countries, promoting cardiovascular health in the developing world: a critical challenge to achieve global health. Washington, DC: National Academies Press (US); 2010 The National Academies Collection: Reports funded by National Institutes of Health.
   Google Scholar
• HeidenreichPATrogdonJGKhavjouOAForecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart AssociationCirculation2011123893394421262990
   PubMed Web of Science ®Google Scholar
• CapewellSFordESCroftJBCritchleyJAGreenlundKJLabartheDRCardiovascular risk factor trends and potential for reducing coronary heart disease mortality in the United States of AmericaBull World Health Organ201088212013020428369
   PubMed Web of Science ®Google Scholar
• StewartSTCutlerDMRosenABForecasting the effects of obesity and smoking on US life expectancyN Engl J Med2009361232252226019955525
   PubMed Web of Science ®Google Scholar
• CrimminsEMPrestonSHCohenBPanel on Understanding Divergent Trends in Longevity in High-Income Countries; Report of the National Research Council of the National AcademiesExplaining Divergent Levels of Longevity in High-Income CountriesWashington, DCThe National Academies Press2011
   Google Scholar
• KonesRIs prevention a fantasy, or the future of medicine? A panoramic view of recent data, status, and direction in cardiovascular preventionTher Adv Cardiovasc Dis201151618121183531
   PubMedGoogle Scholar
• TeoKKOunpuuSHawkenSTobacco use and risk of myocardial infarction in 52 countries in the INTERHEART study: a case-control studyLancet2006368953664765816920470
   PubMed Web of Science ®Google Scholar
• KahnRRobertsonRMSmithREddyDThe impact of prevention on reducing the burden of cardiovascular diseaseCirculation2008118557658518606915
   PubMed Web of Science ®Google Scholar
• The Lp-PLA2 Studies CollaborationLipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 studiesLancet201037597251536154420435228
   PubMed Web of Science ®Google Scholar
• KonesRRosuvastatin, inflammation, C-reactive Protein, JUPITER, and primary prevention of cardiovascular disease – a perspectiveDrug Des Devel Ther20104383413
   PubMed Web of Science ®Google Scholar
• PearsonTAThe prevention of cardiovascular disease: Have we really made progress?Health Aff (Millwood)2007261496017211013
   PubMed Web of Science ®Google Scholar
• HemenwayDWhy We Don’t Spend Enough on Public HealthNew Eng J Med2010362181657165820445178
   PubMed Web of Science ®Google Scholar
• McGlynnEAAschSMAdamsJThe quality of health care delivered to adults in the USN Engl J Med2003348262635264512826639
   PubMed Web of Science ®Google Scholar
• Trust for America’s HealthPrevention for a Healthier America: Investments in Disease Prevention Yields Significant Savings, Stronger CommunitiesWashington, DCTrust for America’s Health72008 Available at: http://healthyamericans.org/reports/prevention08/Prevention08Exec.pdf. Accessed March 24, 2011.
   Google Scholar
• FarleyTADalalMAMostashariFFriedenTRDeaths preventable in the US by improvements in use of clinical preventive servicesAm J Prev Med201038668468520494249
   PubMed Web of Science ®Google Scholar
• National Institute of Health and Clinical ExcellenceNICE Public Health Guidance 25: Prevention of Cardiovascular Disease at Population LevelLondon, UKNational Institute of Health and Clinical Excellence2010
   Google Scholar
• StrasserTReflections on cardiovascular diseasesInterdiscip Sci Rev19783225230
   Web of Science ®Google Scholar
• PippinJJPrimary Prevention Cardiovascular Disease: Better Than DrugsArch Intern Med2010170201860186121059984
   PubMedGoogle Scholar
• De LorgerilMSalenPRabeusMPrimary Prevention Cardiovascular Disease: Better Than Drugs – ReplyArch Intern Med2010170201861
   Google Scholar
• ArmstrongMLMeganMBLipid depletion in atheromatous coronary arteries in rhesus monkeys after regression dietsCirc Res19723066756805025675
   PubMed Web of Science ®Google Scholar
• OrnishDScherwitzLWBillingsJHIntensive lifestyle changes for reversal of coronary heart disease: five-year follow-up of the Lifestyle Heart TrialJAMA199828023200120079863851
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMLeipEPLarsonMGPrediction of lifetime risk for cardiovascular disease by risk factor burden at 50 years of ageCirculation2006113679179816461820
   PubMed Web of Science ®Google Scholar
• KulloIJCooperLTEarly identification of cardiovascular risk using genomics and proteomicsNat Rev Cardiol20107630931720440292
   PubMed Web of Science ®Google Scholar
• LavieCJMilaniRVVenturaHOObesity and cardiovascular disease: risk factor, paradox, and impact of weight lossJ Am Coll Cardiol200953211925193219460605
   PubMed Web of Science ®Google Scholar
• EbrahimSTaylorFWardKBeswickABurkeMDavey SmithGMultiple risk factor interventions for primary prevention of coronary heart diseaseCochrane Database Syst Rev20111CD00156121249647
   PubMed Web of Science ®Google Scholar
• GrahamIAtarDBorch-JohnsenKEuropean guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts)Eur Heart J200728192375241417726041
   PubMed Web of Science ®Google Scholar
• GreenlandPAlpertJSBellerGA2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Developed in collaboration with the American Society of Echocardiography, American Society of Nuclear Cardiology, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, and Society for Cardiovascular Magnetic ResonanceJ Am Coll Cardiol2010562521822199
   Web of Science ®Google Scholar
• Institute of MedicineCrossing the Quality Chasm: A New Health System for the Twenty-first CenturyWashington, DCNational Academy Press2001
   Google Scholar
• BrindisRSpertusJAPresident’s Page: Employing shared decision-making models to improve care and patient value: A cardiovascular Professional initiativeJ Am Coll Cardiol201056242046204821126645
   PubMed Web of Science ®Google Scholar
• WhiteSEffectiveness of public health and education programs for creating awareness of and managing cardiovascular diseasePatient Intelligence201131121
   Google Scholar
• HeneghanCConsiderable uncertainty remains in the evidence for primary prevention of cardiovascular disease [editorial]. The Cochrane Library 2011 (19 Jan) Available at: http://www.thecochranelibrary.com/details/editorial/983199/Considerable-uncertainty-remains-in-the-evidence-for-primary-prevention-of-cardi.html. Accessed March 24, 2011.
   Google Scholar
• FinucaneMMStevensGACowanMJon behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Body Mass Index)National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participantsLancet2011377976555756721295846
   PubMed Web of Science ®Google Scholar
• FarzadfarFFinucaneMMDanaeiGon behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Cholesterol)National, regional, and global trends in serum total cholesterol since 1980: systematic analysis of health examination surveys and epidemiological studies with 321 country-years and 3·0 million participantsLancet2011377976557858621295847
   PubMed Web of Science ®Google Scholar
• DanaeiGFinucaneMMLinJKon behalf of the Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure)National, regional, and global trends in systolic blood pressure since 1980: systematic analysis of health examination surveys and epidemiological studies with 786 country-years and 5·4 million participantsLancet2011377976556857721295844
   PubMed Web of Science ®Google Scholar
• AnandSSYusufSStemming the global tsunami of cardiovascular diseaseLancet2011377976552953221295845
   PubMed Web of Science ®Google Scholar
• CapewellSHayesDKFordESLife-years gained among US adults from modern treatments and changes in the prevalence of 6 coronary heart disease risk factors between 1980 and 2000Am J Epidemiol2009170222923619541856
   PubMed Web of Science ®Google Scholar
• BjörckLRosengrenABennettKLappasGCapewellSModelling the decreasing coronary heart disease mortality in Sweden between 1986 and 2002Eur Heart J20093091046105619141562
   PubMed Web of Science ®Google Scholar
• YoungFCapewellSFordESCritchleyJACoronary Mortality Declines in the US Between 1980 and 2000. Quantifying the Contributions from Primary and Secondary PreventionAmer J Prev Med201039322823420709254
   PubMed Web of Science ®Google Scholar
• USDHHS, National Center for Health StatisticsSecond National Health and Nutrition Examination Survey (NHANES II)Hyattsville, MDCDC19761980
   Google Scholar
• USDHHS, National Center for Health StatisticsSecond National Health and Nutrition Examination Survey (Continuous NHANES)Hyattsville, MDCDC19992002
   Google Scholar
• BriffaTGHobbsMSTonkinAPopulation trends of recurrent coronary heart disease event rates remain highCirc Cardiovasc Qual Outcomes20114110711321139089
   PubMed Web of Science ®Google Scholar
• RoseGThe Strategy of Preventive MedicineOxford, UKOxford University Press1992
   Google Scholar
• RoseGStrategy of prevention: lessons from cardiovascular diseaseBr Med J (Clin Res Ed)1981282627918471851
   PubMed Web of Science ®Google Scholar
• RoseGSick individuals and sick populationsInt J Epidemiol198514132383872850
   PubMed Web of Science ®Google Scholar
• RoseGStrategies of prevention: the individual and the populationMarmotMElliottPCoronary Heart Disease Epidemiology: From Aetiology to Public HealthOxford, UKOxford University Press1991631641
   Google Scholar
• HingoraniADPsatyBMPrimary Prevention of Cardiovascular Disease. Time to Get More or Less Personal?JAMA2009302192144214519920239
   PubMed Web of Science ®Google Scholar
• BergerJSJordanCOLloyd-JonesDMBlumenthalRSScreening for cardiovascular risk in asymptomatic patientsJ Am Coll Cardiol201055121169117720298922
   PubMed Web of Science ®Google Scholar
• FryarCDHirschREberhardtMSYoonSSWrightJDHypertension, high serum total cholesterol, and diabetes: Racial and ethnic prevalence differences in US adults, 1999–2006 NCHS data brief, no 36.Hyattsville, MDNational Center for Health Statistics4262010 Available at: http://www.cdc.gov/nchs/default.htm. Accessed March 24, 2011.
   Google Scholar
• RogerVLGoASLloyd-JonesDMon behalf of the American Heart Association Statistics Committee and Stroke Statistics CommitteeHeart Disease and Stroke Statistics–2011 Update: A Report From the American Heart AssociationCirculation20111234e18e20921160056
   PubMed Web of Science ®Google Scholar
• PaezKAZhaoLHwangWRising Out-Of-Pocket Spending For Chronic Conditions: A Ten-Year TrendHealth Aff (Millwood)2009281152519124848
   PubMed Web of Science ®Google Scholar
• LeviJVinterSSt LaurentRSegalLMF as in Fat 2010 Finds Continued Rise in Nation’s Obesity Rates Trust for America’s Health, and the Robert Wood Johnson Foundation6292010 Available at: http://www.rwjf.org/pr/product.jsp?id=65469. Accessed March 24, 2011.
   Google Scholar
• BarnesPMHeymanKMFreemanGSchillerJSEarly release of selected estimates based on data from the 2009 National Health Interview SurveyHyattsville, MDNational Center for Health Statistics6162010 Available at: http://www.cdc.gov/nchs/nhis.htm. Accessed March 24, 2011.
   Google Scholar
• National Center for Health StatisticsHealth, United States, 2010 CDC. Hyattsville MD 563 p2/16/2011. Available at: http://www.cdc.gov/nchs/data/hus/hus10.pdf. Accessed March 24, 2011.
   Google Scholar
• Heart and Stroke Foundation2011 Heart and Stroke Foundation Report on Canadians’ Health. Denial is putting Canadians at high risk of cutting their lives short212011Ottawa, ON Available at: www.heartandstroke.com/atf/cf/%7B99452d8b-e7f1-4bd6-a57d-b136ce6c95bf%7D/lr-FINAL-Reportcard%20HSF_2011-english.pdf. Accessed March 24, 2011.
   Google Scholar
• HuangESBasuAO’gradyMCaprettaJCProjecting the Future Diabetes Population Size and Related Costs For The USDiab Care2009321222252229
   PubMed Web of Science ®Google Scholar
• BoyleJPThompsonTJGreggEWBarkerLEWilliamsonDFProjection of the year 2050 burden of diabetes in the US adult population: dynamic modeling of incidence, mortality, and prediabetes prevalencePopulation Health Metrics201082920969750
   PubMed Web of Science ®Google Scholar
• YancyCWIs Ideal Cardiovascular Health Attainable?Circulation2011123883583721321158
   PubMed Web of Science ®Google Scholar
• KonesRLow-fat versus low-carbohydrate diets, weight loss, vascular health, and prevention of coronary artery disease: the evidence, the reality, the challenge, and the hopeNutr Clin Pract201025552854120962314
   PubMed Web of Science ®Google Scholar
• HeberDAn integrated view of obesityAm J Clin Nutr2010911280S283S19923373
   PubMed Web of Science ®Google Scholar
• BrayGALet’s treat obesity seriouslyAmer Fam Physician201081121449145520540483
   PubMed Web of Science ®Google Scholar
• Number of Americans with Diabetes Rises to Nearly 26 Million More than a third of adults estimated to have prediabetes CDC Press Release,1132011 Available at: http://www.cdc.gov/media/releases/2011/p0126_diabetes.html. Accessed March 24, 2011.
   Google Scholar
• DanaeiGFriedmanABOzaSMurrayCJLEzzatiMDiabetes prevalence and diagnosis in US states: analysis of health surveysPopul Health Metr200971619781056
   PubMedGoogle Scholar
• HammondRALevineRThe economic impact of obesity in the United StatesDiabetes Metab Syndr Obes2010328529521437097
   PubMedGoogle Scholar
• VickersMHSLobodaDMPrenatal nutritional influences on obesity risk in offspringNutrition and Dietary Supplements20102137149
   Google Scholar
• FordESLiCZhaoGTsaiJTrends in obesity and abdominal obesity among adults in the United States from 1999–2008Int J Obes (Lond)20113573674320820173
   PubMed Web of Science ®Google Scholar
• BambsCKipKEDingaAMulukutlaSRAiyerANReisSELow Prevalence of “Ideal Cardiovascular Health” in a Community-Based Population: The Heart Strategies Concentrating on Risk Evaluation (Heart SCORE) StudyCirculation2011123885085721321154
   PubMed Web of Science ®Google Scholar
• CDC National Center for Health StatisticsCDC mortality data, 2008: CDC latest release mortality data, 2005 Available at: www.cdc.gov/nchs/fastats/deaths.htm.
   Google Scholar
• SackerAHeadJBartleyMImpact of coronary heart disease on health functioning in an aging population: are there differences according to socioeconomic position?Psychosom Med200870213314018256343
   PubMed Web of Science ®Google Scholar
• AllenderSScarboroughPPetoVEuropean cardiovascular disease statistics 2008European Heart Network2008 Available at: www.heartstats.org/uploads/documents%5Cproof30NOV2007.pdf.
   Google Scholar
• WHO Statistical Information SystemMortality data for ICD 10 codings Available at: www.who.int/whosis/database/mort/download/ftp/morticd10.zip.
   Google Scholar
• FordESCapewellSCoronary heart disease mortality among young adults in the US from 1980 to 2002: concealed leveling or mortality ratesJ Am Coll Cardiol200750222128213218036449
   PubMed Web of Science ®Google Scholar
• AyerJSteinbeckKPlacing the cardiovascular risk of childhood obesity in perspectiveInt J Obes201034145
   Web of Science ®Google Scholar
• BerensonGCardiovascular health promotion for children: A model for a Parish (County)-wide program (implementation and preliminary resultsPrev Cardiol2010131232820021623
   PubMedGoogle Scholar
• Prevalence of abnormal lipid levels among youths – United States, 1999–2006Morbidity and Mortality Weekly Report (MMWR)2010590229331222010 Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5902a1.htm#. Accessed March 24, 2011.
   PubMedGoogle Scholar
• BerensonGSSrinivasanSRCardiovascular Risk in Young Persons: Secondary or Primordial Prevention?Ann Int Med2010153320220320679564
   PubMed Web of Science ®Google Scholar
• PletcherMJBibbins-DomingoKLiuKNonoptimal lipids commonly present in young adults and coronary calcium later in life: The CARDIA (Coronary Artery Risk Development in Young Adults) StudyAnn Intern Med2010153313714620679558
   PubMed Web of Science ®Google Scholar
• FalkENaghaviMShahPKLegislating screening for atherosclerosisJAMA2008299182147214818477779
   PubMed Web of Science ®Google Scholar
• GillespieCKuklinaEVBrissPABlairNAHongYVital signs: prevalence, treatment, and control of hypertension – United States, 1999–2002 and 2005–2008MMWR20116004103108 Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm60e0201a1.htm Accessed March 24, 2011.21293325
   PubMedGoogle Scholar
• KuklinaEShawKMY HongYVital signs: prevalence, treatment, and control of high levels of low-density lipoprotein cholesterol – United States, 1999–2002 and 2005–2008MMWR20116004109114 Available at: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm60e0201a2.htm. Accessed March 24, 2011.
   Google Scholar
• KatchHMeadHThe role of self-efficacy in cardiovascular disease self-management: a review of effective programsPatient Intelligence201023344
   Google Scholar
• BosworthHBChallenges and strategies to improve patient health literacy and competenciesPatient Intelligence201021925
   Google Scholar
• McNealTMColbertCYCableCPatients’ attention to and understanding of adverse drug reaction warningsPatient Intelligence201025968
   Google Scholar
• LaufsURettig-EwenVBöhmMStrategies to improve drug adherenceEur Heart J201132326426820729544
   PubMed Web of Science ®Google Scholar
• FischerMAStedmanMRLiiJPrimary Medication Non-Adherence: Analysis of 195,930 Electronic PrescriptionsJ Gen Int Med2010254284290
   PubMed Web of Science ®Google Scholar
• LardizabalJADeedwaniaPCBenefits of statin therapy and compliance in high risk cardiovascular patientsVasc Health Risk Manag2010684385320957130
   PubMedGoogle Scholar
• HoPMMagidDJShetterlySMMedication nonadherence isassociated with a broad range of adverse outcomes in patients with coronary artery diseaseAm Heart J2008155477272918371492
   PubMed Web of Science ®Google Scholar
• DonnellyLADoneyASMorrisADPalmerCNConnanPTLong-term adherence to statin treatment in diabetesDiabet Med200825785085518644071
   PubMed Web of Science ®Google Scholar
• KotsevaKWoodDDe BackerGEUROASPIRE Study GroupCardiovascular prevention guidelines in daily practice: a comparison of EUROASPIRE I, II, and III surveys in eight European countriesLancet2009373966792994019286092
   PubMed Web of Science ®Google Scholar
• PopkinBMRecent dynamics suggest selected countries catching up to US obesityAm J Clin Nutr2010911284S288S19906804
   PubMed Web of Science ®Google Scholar
• ShawJESicreeRAZimmetPZGlobal estimates of the prevalence of diabetes for 2010 and 2030Diabetes Res Clin Pract201087141419896746
   PubMed Web of Science ®Google Scholar
• ZhangPZhangXBrownJGlobal healthcare expenditure on diabetes for 2010 and 2030Diabetes Res Clin Pract201087329330120171754
   PubMed Web of Science ®Google Scholar
• SimmonsRKUnwinNGriffinSJInternational Diabetes Federation: An update of the evidence concerning the prevention of type 2 diabetesDiabetes Res Clin Pract201087214314919913319
   PubMed Web of Science ®Google Scholar
• JoshiRJanSWuYMacMahonSGlobal inequalities in access to cardiovascular health care: our greatest challengeJ Am Coll Cardiol200852231817182519038678
   PubMed Web of Science ®Google Scholar
• YusufSHawkenSOunpuuSEffect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTER-HEART study): case-control studyLancet2004364943893795215364185
   PubMed Web of Science ®Google Scholar
• ReddyKSPrabhakaranDJeemonPEducational status and cardiovascular risk profile in IndiansProc Natl Acad Sci U S A2007104162631626817923677
   PubMed Web of Science ®Google Scholar
• FrancoMCooperRSBilalUFusterVChallenges and opportunities for cardiovascular disease preventionAmer J Med201112429510221295188
   PubMed Web of Science ®Google Scholar
• KaveyE-RWDanielsSRLauerRMAtkinsDLHaymanLLTaubertKAmerican Heart Association guidelines for primary prevention of atherosclerotic cardiovascular disease beginning in childhoodCirculation2003107111562156612654618
   PubMed Web of Science ®Google Scholar
• McMahanCAGiddingSSViikariJSAAssociation of Pathobiologic determinants of atherosclerosis in youth risk score and 15-year change in risk score with carotid artery intima–media thickness in young adults (from the Cardiovascular Risk in Young Finns Study)Am J Cardiol200710071124112917884375
   PubMed Web of Science ®Google Scholar
• ShahASDolanLMKimballTRInfluence of duration of diabetes, glycemic control, and traditional cardiovascular risk factors on early atherosclerotic vascular changes in adolescents and young adults with type 2 diabetes mellitusJ Clin Endocrinol Metab200994103740374519723759
   PubMed Web of Science ®Google Scholar
• NewmanWPWattigneyWBerensonGSAutopsy studies in United States children and adolescents: relationship of risk factors to atherosclerotic lesionsAnn N Y Acad Sci199162316252042824
   PubMed Web of Science ®Google Scholar
• StrongJPMalcomGTMcMahanCAPrevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth StudyJAMA1999281872773510052443
   PubMed Web of Science ®Google Scholar
• CorvalánCUauyRKainJMartorellRObesity indicators and cardiometabolic status in 4-y-old childrenAm J Clin Nutr201091116617419923378
   PubMed Web of Science ®Google Scholar
• MaurasNDelGiornoCKollmanCObesity without established comorbidities of the metabolic syndrome is associated with a proinflammatory and prothrombotic state, even before the onset of puberty in childrenJ Clin Endocrinol Metab20109531060106820061420
   PubMed Web of Science ®Google Scholar
• MileiJOttavianiGLavezziAMGranaDRStellaIMatturiLPerinatal and infant early atherosclerotic coronary lesionsCan J Cardiol200824213714118273488
   PubMed Web of Science ®Google Scholar
• TuzcuEMKapadiaSRTutarEHigh prevalence of coronary atherosclerosis in asymptomatic teenagers and young adults: evidence from intravascular ultrasoundCirculation2001103222705271011390341
   PubMed Web of Science ®Google Scholar
• EnosWFHolmesRHBeyerJCoronary disease among United States soldiers killed in action in Korea: preliminary reportJAMA19535521210901093
   Web of Science ®Google Scholar
• McNamaraJJMolotMAStrempleJFCuttingRTCoronary artery disease in combat casualties in VietnamJAMA19712167118518875108403
   PubMed Web of Science ®Google Scholar
• NewmanWPFreedmanDSVoorsAWRelation of serum lipoprotein levels and systolic blood pressure to early atherosclerosis: the Bogalusa Heart StudyN Engl J Med198631431381443455748
   PubMed Web of Science ®Google Scholar
• BerensonGSSrinivasanSRBaoWNewmanWP3rdTracyREWattigneyWAAssociation between multiple cardiovascular risk factors and atherosclerosis in children and young adults: the Bogalusa Heart StudyN Engl J Med199833823165016569614255
   PubMed Web of Science ®Google Scholar
• NguyenQMNSrinivasanSRXuJ-HChenWKieltykaLBerensonGSUtility of childhood glucose homeostasis variables in predicting adult diabetes and related cardiometabolic risk factorsDiabetes Care201033367067520009096
   PubMed Web of Science ®Google Scholar
• BerensonGSWattigneyWATracyREAtherosclerosis of the aorta and coronary arteries and cardiovascular risk factors in persons aged 6 to 30 years and studied at necropsy (The Bogalusa Heart Study)Am J Cardiol19927098518581529936
   PubMed Web of Science ®Google Scholar
• BerensonGSCardiovascular risk begins in childhood. A time for actionAm J Prev Med2009371 SupplS1S219524149
   PubMed Web of Science ®Google Scholar
• TwiskJWKemperHCMellenberghGJMathematical and analytical aspects of trackingEpidemiol Rev19941621651827713175
   PubMed Web of Science ®Google Scholar
• GarcíaRGPérezMMaasRSchwedhelmEBogerRHLopez-JaramilloPPlasma concentrations of asymmetric dimethylarginine (ADMA) in metabolic syndromeInt J Cardiol2007122217617817234281
   PubMed Web of Science ®Google Scholar
• GillumRFAssociation of serum C-reactive protein and body fat distribution and overweight in Mexican American childrenJ Natl Med Assoc200395754555212911252
   PubMed Web of Science ®Google Scholar
• López-JaramilloPHerreraEGarcíaRGCamachoPACastilloVRRelationship of body mass index, C-reactive protein and blood pressure in a Hispanic pediatric populationAm J Hypertens200821552753218437144
   PubMed Web of Science ®Google Scholar
• MagnussenCGThomsonRClelandVJUkoumunneOCDwyerTVennAFactors affecting the stability of blood lipid and lipoprotein levels from youth to adulthood: evidence from the Childhood Determinants of Adult Health StudyArch Pediatr Adolesc Med20111651687621199983
   PubMedGoogle Scholar
• PDAY Research GroupRelationship of atherosclerosis in young men to serum lipoprotein cholesterol concentrations and smoking: a preliminary report from the Pathological Determinants of Atherosclerosis in Youth (PDAY) Research GroupJAMA199026423301830242243430
   PubMed Web of Science ®Google Scholar
• WisslerRWStrongJPthe PDAY Research GroupRisk factors and progression of atherosclerosis in youthAm J Pathol19981534102310339777934
   PubMed Web of Science ®Google Scholar
• McGillHCJrMcMahanCAGiddingSSPreventing heart disease in the 21st century: implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) StudyCirculation200811791216122718316498
   PubMed Web of Science ®Google Scholar
• McGillHCMcMahanCAStarting early to control all risk factors in order to prevent coronary heart diseaseClinical Lipidol2010518793
   Web of Science ®Google Scholar
• JuonalaMViikariJSAKähönenMLife-time risk factors and progression of carotid atherosclerosis in young adults: the Cardiovascular Risk in Young Finns studyEur Heart J201031141745175120501481
   PubMed Web of Science ®Google Scholar
• JuonalaMMagnussenCGVennAInfluence of age on associations between childhood risk factors and carotid intima-media thickness in adulthood: The Cardiovascular Risk in Young Finns Study, the Childhood Determinants of Adult Health Study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) ConsortiumCirculation2010122242514252021126976
   PubMed Web of Science ®Google Scholar
• GiddingSSAssembling evidence to justify prevention of atherosclerosis beginning in youthCirculation2010122242493249421126975
   PubMed Web of Science ®Google Scholar
• DanielsSRGreerFRCommittee on NutritionLipid screening and cardiovascular health in childhoodPediatrics2008122119820818596007
   PubMed Web of Science ®Google Scholar
• O’GormanCSMO’NeillMBConwellLSConsidering statins for cholesterol-reduction in children if lifestyle and diet changes do not improve their health: a review of the risks and benefitsVasc Health Risk Manag20117114
   Google Scholar
• CohenHStein-ZamirCHamielOIsraeli guidelines for the management of hypercholesterolemia in children and adolescents. Report of the pediatric association expert group. e-SPENEur e-Journal Clin Nutr Metabol201053e132e143
   Google Scholar
• IughettiLBruzziPPredieriBEvaluation and management of hyperlipidemia in children and adolescentsCurr Opin Ped2010224485493
   Web of Science ®Google Scholar
• GoodingHCD de FerrantiSCardiovascular risk assessment and cholesterol management in adolescents: getting to the heart of the matterCurr Opin Ped2010224398404
   Web of Science ®Google Scholar
• WierzbickiASViljoenAHyperlipidaemia in paediatric patients: the role of lipid-lowering therapy in clinical practiceDrug Safety201033211512520082538
   PubMed Web of Science ®Google Scholar
• LebenthalYHorvathADziechciarzPSzajewskaHShamirRAre treatment targets for hypercholesterolemia evidence based? Systematic review and meta-analysis of randomised controlled trialsArch Dis Child201095967368020515970
   PubMed Web of Science ®Google Scholar
• De FerrantiSLudwigDSStorm over Statins – The Controversy Surrounding Pharmacologic Treatment of ChildrenN Engl J Med2008359131309131218815394
   PubMed Web of Science ®Google Scholar
• SteinbergDGlassCKWitztumJLEvidence mandating earlier and more aggressive treatment of hypercholesterolemiaCirculation2008118667267718678783
   PubMed Web of Science ®Google Scholar
• SimellONiinikoskiHRonnemaaTCohort Profile: The STRIP Study (Special Turku Coronary Risk Factor Intervention Project), an infancy-onset dietary and life-style intervention trialInt J Epidemiol200938365065518430753
   PubMed Web of Science ®Google Scholar
• KuklinaEVYoonPWKeenanNLPrevalence of coronary heart disease risk factors and screening for high cholesterol levels among young adults, United States, 1999–2006Ann Fam Med20108432733320644187
   PubMed Web of Science ®Google Scholar
• GiddingSSLichtensteinAHFaithMSImplementing American Heart Association Pediatric and Adult Nutrition Guidelines: A Scientific Statement From the American Heart Association Nutrition Committee of the Council on Nutrition, Physical Activity and Metabolism, Council on Cardiovascular Disease in the Young, Council on Arteriosclerosis, Thrombosis and Vascular Biology, Council on Cardiovascular Nursing, Council on Epidemiology and Prevention, and Council for High Blood Pressure ResearchCirculation200911981161117519255356
   PubMed Web of Science ®Google Scholar
• BroylesSKatzmarzykPTSrinivasanSRThe pediatric obesity epidemic continues unabated in Bogalusa, LouisianaPediatrics2010125590090520368311
   PubMed Web of Science ®Google Scholar
• US Preventive Services Task ForceScreening for obesity in children and adolescents: US Preventive Services Task Force recommendation statementPediatrics2010125236136720083515
   PubMed Web of Science ®Google Scholar
• National Center for Chronic Disease Prevention and Health PromotionHealthy Youth! Available at: http://www.cdc.gov/HealthyYouth. Accessed May 16, 2011.
   Google Scholar
• AugustGPrevention and treatment of pediatric obesity: an Endocrine Society clinical practice guidelines based on expert opinionJ Clin Endocrinol Metab200893124576459918782869
   PubMed Web of Science ®Google Scholar
• KannelWBMcGeeDGordonTA general cardiovascular risk profile: the Framingham StudyAm J Cardiol19763814651132862
   PubMed Web of Science ®Google Scholar
• GordonTKannelWBMultiple risk functions for predicting coronary heart disease: the concept, accuracy, and applicationAm Heart J19821036103110397044082
   PubMed Web of Science ®Google Scholar
• AndersonMWilsonPWOdellPMKannelWBAn updated coronary risk profile: a statement for health professionalsCirculation19918313563621984895
   PubMed Web of Science ®Google Scholar
• WilsonPWFD’AgostinoRBLevyDBelangerAMSilbershatzHKannelWBPrediction of coronary heart disease using risk factor categoriesCirculation19989718183718479603539
   PubMed Web of Science ®Google Scholar
• ConroyRMPyoralaKFitzgeraldAPEstimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE projectEur Heart J20032411987100312788299
   PubMed Web of Science ®Google Scholar
• Hippisley-CoxJCouplandCVinogradovaYRobsonJMayMBrindlePDerivation and validation of QRISK, a new cardiovascular disease risk score for the United Kingdom: prospective open cohort studyBMJ2007335761113614717615182
   PubMed Web of Science ®Google Scholar
• WoodwardMBrindlePTunstall-PedoeHAdding social deprivation and family history to cardiovascular risk assessment: the ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC)Heart200793217217617090561
   PubMed Web of Science ®Google Scholar
• Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final reportCirculation2002106253143342112485966
   PubMed Web of Science ®Google Scholar
• D’AgostinoRBSrGrundySSullivanLMWilsonPfor the CHD Risk Prediction GroupValidation of the Framingham coronary disease prediction scores. results of a multiple ethnic groups investigationJAMA2001286218018711448281
   PubMed Web of Science ®Google Scholar
• AssmannGCullenPSchulteHSimple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the Prospective Cardiovascular Münster (PROCAM) studyCirculation2002105331031511804985
   PubMed Web of Science ®Google Scholar
• RidkerPMBuringJERifaiNCookNRDevelopment and validation of improved algorithms for the assessment of global cardiovascular risk in women: the Reynolds Risk ScoreJAMA2007297661161917299196
   PubMed Web of Science ®Google Scholar
• RidkerPMPaynterNPRifaiNGazianoJMCookNRC-reactive protein and parental history improve global cardiovascular risk prediction: the Reynolds risk score for menCirculation2008118222243225118997194
   PubMed Web of Science ®Google Scholar
• PearsonTABlairSNDanielsSRAHA guidelines for primary prevention of cardiovascular disease and stroke: 2002 update: consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseasesCirculation2002106338839112119259
   PubMed Web of Science ®Google Scholar
• Guide to Clinical Preventive Services 2007: Recommendations of the US Preventive Services Task Force. Agency for Healthcare Research and Quality Pub. No. 07-0510092007 Available at: https://www.oxhp.com/secure/materials/member/adult_preventive.pdf. Accessed March 24, 2011.
   Google Scholar
• De BackerGAmbrosioniEBorch-JohnsenKEuropean guidelines on cardiovascular disease and prevention in clinical practiceAtherosclerosis2003171114515514686332
   PubMed Web of Science ®Google Scholar
• De BackerGGRisk factors and prevention of cardiovascular disease: a reviewDialogues Cardiovasc Med20081328399
   Google Scholar
• DentTHSPredicting the risk of coronary heart disease: I. The use of conventional risk markersAtherosclerosis2010213234535120637467
   PubMed Web of Science ®Google Scholar
• NasirKBudoffMJWongNDFamily history of premature coronary heart disease and coronary artery calcification: Multi-Ethnic Study of Atherosclerosis (MESA)Circulation2007116661962617646582
   PubMed Web of Science ®Google Scholar
• ParikhNIHwangS-JLarsonMGParental occurrence of premature cardiovascular disease predicts increased coronary artery and abdominal aortic calcification in the Framingham Offspring and Third Generation CohortsCirculation2007116131473148117785619
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMNamB-HD’AgostinoRBSrParental cardiovascular disease as a risk factor for cardiovascular disease in middle-aged adults: a prospective study of parents and offspringJAMA2004291182204221115138242
   PubMed Web of Science ®Google Scholar
• Pohjola-SintonenSRissanenALiskolaPLuomanmäkiKFamily history as a risk factor of coronary heart disease in patients under 60 years of ageEur Heart J19981922352399519316
   PubMed Web of Science ®Google Scholar
• YoungerJFFamily history is important in estimating coronary riskBMJ2000321725844810991590
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMDyerARWangRDaviglusMLGreenlandPRisk factor burden in middle age and lifetime risks for cardiovascular and non-cardiovascular death (Chicago Heart Association Detection Project in Industry)Am J Cardiol200799453554017293199
   PubMed Web of Science ®Google Scholar
• D’AgostinoRBSrVasanRSPencinaMJGeneral cardiovascular risk profile for use in primary care: the Framingham Heart StudyCirculation2008117674375318212285
   PubMed Web of Science ®Google Scholar
• De KoningJSKlazingaNSKoudstaalPJQuality of care in stroke prevention: results of an audit study among general practitionersPrev Med200438212913614715204
   PubMed Web of Science ®Google Scholar
• De MuylderRLorantVPaulusDObstacles to cardiovascular prevention in general practiceActa Cardiol200459211912515139651
   PubMed Web of Science ®Google Scholar
• EatonCBGalliherJMMcBridePEFamily physician’s knowledge, beliefs, and self-reported practice patterns regarding hyperlipidemia: a National Research Network (NRN) surveyJ Am Board Fam Med2006191465316492005
   PubMed Web of Science ®Google Scholar
• GrahamIMStewartMHertogMGFactors impeding the implementation of cardiovascular prevention guidelines: findings from a survey conducted by the European Society of CardiologyEur J Cardiovasc Prev Rehabil200613583984517001227
   PubMedGoogle Scholar
• FusterVAre predictive risk scores useful?Nat Rev Cardiol20096849319633674
   PubMed Web of Science ®Google Scholar
• GuptaMKajilMHirjikakaSAccuracy of Cardiovascular (CV) Risk Stratification by Canadian Primary Care Physicians: Preliminary Results From the Primary Care Audit of Global Risk Management (PARADIGM) Study, Abstract 16946Circulation201012221 SupplA16946
   Web of Science ®Google Scholar
• SheridanSLCrespoEDoes the routine use of global coronary heart disease risk scores translate into clinical benefits or harms? A systematic review of the literatureBMC Health Serv Res200886018366711
   PubMed Web of Science ®Google Scholar
• KonesRRecent advances in the management of chronic stable angina I: Approach to the patient, diagnosis, pathophysiology, risk stratification, and gender disparitiesVasc Health Risk Manag2010663565620730020
   PubMedGoogle Scholar
• MadhokVFaheyTCardiovascular risk estimation: important but may be inaccurateBMJ20063327555142216737981
   PubMed Web of Science ®Google Scholar
• AkosahKOSchaperACogbillCSchoenfeldPPreventing myocardial infarction in the young adult in the first place: how do the National Cholesterol Education Panel III guidelines perform?J Am Coll Cardiol20034191475147912742284
   PubMed Web of Science ®Google Scholar
• National Center for Health StatisticsThird National Health and Nutrition Examination Survey III. Public-Use Data files Available at: http://www.cdc.gov/nchs/nhanes/nh3data.htm. Accessed May 16, 2011.
   Google Scholar
• Cavanaugh-HusseyMWBerryJDLloyd-JonesDMWho exceeds ATP-III risk thresholds? Systematic examination of the effect of varying age and risk factor levels in the ATP-III risk assessment poolPrev Med200847661962318718484
   PubMed Web of Science ®Google Scholar
• FeemanWJrBGS graph predicts better than the Framingham Risk ScoreJ Clin Lipidol201043203
   Google Scholar
• CooperJAMillerGJHumphriesSEA comparison of the PROCAM and Framingham point-scoring systems for estimation of individual risk of coronary heart disease in the Second Northwick Park Heart StudyAtherosclerosis200518119310015939059
   PubMed Web of Science ®Google Scholar
• OrfordJLSessoHDStedmanMA comparison of the Framingham and European Society of Cardiiology coronary heart disease risk prediction models in the same normative aging studyAm Heart J200214419510012094194
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMCardiovascular risk prediction. Basic concepts, current status, and future directionsCirculation2010121151768177720404268
   PubMed Web of Science ®Google Scholar
• VasanRSSullivanLMWilsonPWRelative importance of borderline and elevated levels of coronary heart disease risk factorsAnn Intern Med2005142639340215767617
   PubMed Web of Science ®Google Scholar
• BerryJDLiuKFolsomARPrevalence and progression of subclinical atherosclerosis in younger adults with low short-term but high lifetime estimated risk for cardiovascular disease: the CARDIA and MESA studiesCirculation2009119338238919139385
   PubMed Web of Science ®Google Scholar
• MoscaLBankaCLBenjaminEJEvidence-based guidelines for cardiovascular disease prevention in women: 2007 updateCirculation2007115111481150117309915
   PubMedGoogle Scholar
• RohatgiAKKheraAThe Upcoming ATP IV GuidelinesLipid Spin20108469
   Google Scholar
• GenestJMcPhersonRFrohlichJ2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult – 2009 recommendationsCan J Cardiol2009251056757919812802
   PubMed Web of Science ®Google Scholar
• FerrarioCMMooreMABestermannWJrCOSEHC global vascular risk management quality improvement program: rationale and designVasc Health Risk Manag201061135114521931496
   PubMedGoogle Scholar
• MinJKShawLJDevereauxRBProgostic value of multidetector coronary computed tomographic angiography for prediction of all-cause mortalityJ Am Coll Cardiol200750121161117017868808
   PubMed Web of Science ®Google Scholar
• JohnsonKMDoweDABrinkJATraditional clinical risk assessment tools do not accurately predict coronary atherosclerotic plaque burden: a CT angiography studyAm J Roentgenol2009192123524319098205
   PubMed Web of Science ®Google Scholar
• JohnsonKMDoweDAThe detection of any coronary calcium outperforms Framingham Risk Score as a first step in screening for coronary atherosclerosisAm J Roentgenol201019451235124320410409
   PubMed Web of Science ®Google Scholar
• HechtHSThe deadly double standard. The saga of screening for subclinical atherosclerosisAm J Cardiol2008101121805180718549864
   PubMed Web of Science ®Google Scholar
• CooneyMTDudinaALGrahamIMValue and limitations of existing scores for the assessment of cardiovascular riskJ Am Coll Cardiol200954141209122719778661
   PubMed Web of Science ®Google Scholar
• CooneyMTDudinaAD’AgostinoRGrahamIMCardiovascular risk-estimation systems in primary prevention. Do they differ? Do they make a difference? Can we see into the future?Circulation2010122330031020644026
   PubMed Web of Science ®Google Scholar
• ShahPKScreening asymptomatic subjects for subclinical atherosclerosis. Can we, does it matter, and should we?J Am Coll Cardiol20105629810520620724
   PubMed Web of Science ®Google Scholar
• LauerMSScreening asymptomatic subjects for subclinical atherosclerosis. Not so obviousJ Am Coll Cardiol201056210610820620725
   PubMed Web of Science ®Google Scholar
• LordSJIrwigLSimesRJWhen is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized trials?Ann Intern Med20061441185085516754927
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMLiuKTianLGreenlandPNarrative review: assessment of C-reactive protein in risk prediction for cardiovascular diseaseAnn Intern Med20061451354216818927
   PubMed Web of Science ®Google Scholar
• Lloyd-JonesDMTianLPredicting cardiovascular risk. So what do we do now?Arch Intern Med2006166131342134416831997
   PubMedGoogle Scholar
• DentTHSPredicting the risk of coronary heart disease. II: The role of novel molecular biomarkers and genetics in estimating risk, and the future of risk predictionAtherosclerosis2010213235236220619412
   PubMed Web of Science ®Google Scholar
• WangTJGonaPLarsonMGMultiple biomarkers for the prediction of first major cardiovascular events and deathN Eng J Med20063552526312639
   PubMed Web of Science ®Google Scholar
• ZetheliusBBerglundLSundstromJUse of multiple biomarkers to improve the prediction of death from cardiovascular causesN Engl J Med2008358202107211618480203
   PubMed Web of Science ®Google Scholar
• De LemosJARohatgiASeparating the contenders from the pretenders: competitive high-throughput biomarker screening in large population-based studiesCirculation2010121222381238320497975
   PubMed Web of Science ®Google Scholar
• MelanderONewton-ChehCAlmgrenPNovel and conventional biomarkers for prediction of incident cardiovascular events in the communityJAMA20093021495719567439
   PubMed Web of Science ®Google Scholar
• BlankenbergSZellerTSaarelaOfor the MORGAM ProjectContribution of 30 biomarkers to 10-year cardiovascular risk estimation in 2 population cohorts: The MONICA, risk, genetics, archiving, and monograph (morgam) biomarker projectCirculation2010121222388239720497981
   PubMed Web of Science ®Google Scholar
• ArsenaultBJBarterPDeMiccoDAfor the TNT Study InvestigatorsPrediction of cardiovascular events in statin-treated stable coronary patients by lipid and nonlipid biomarkersJ Am Coll Cardiol2011571636921185503
   PubMed Web of Science ®Google Scholar
• BerryJDDyerACarnethonMTrianLGreenlandPLloyd-JonesDMAssociation of traditional risk factors with cardiovascular death across 0 to 10, 10 to 20, and >20 years follow-up in men and womenAm J Cardiol20081011899418157971
   PubMed Web of Science ®Google Scholar
• PersellSDZeiCCameronKAZielinskiMLloyd-JonesDMPotential use of 10-year and lifetime coronary risk information for preventive cardiology prescribing decisions: a primary care physician surveyArch Int Med2010170547047720212185
   PubMedGoogle Scholar
• Lloyd-JonesDMWilsonPWFLarsonMGFramingham risk score and prediction of lifetime risk for coronary heart diseaseAm J Cardiol2004941202415219502
   PubMed Web of Science ®Google Scholar
• MarmaAKBerryJDNingHPersellSDLloyd-JonesDMDistribution of 10-Year and Lifetime Predicted Risks for Cardiovascular Disease in US Adults: Findings From the National Health and Nutrition Examination Survey 2003 to 2006Circ Cardiovasc Qual Outcomes20103181420123666
   PubMed Web of Science ®Google Scholar
• CrouseJRIIIBotsMLEvansGWDoes baseline carotid intima-media thickness modify the effect of rosuvastatin when compared with placebo on carotid intima-media thickness progression? The METEOR studyEur J Cardiovasc Prev Rehabil201017222322920038840
   PubMedGoogle Scholar
• ReinerAPCarlsonCSThyagarajanBSoluble P-selectin, SELP polymorphisms, and atherosclerotic risk in European-American and African-African young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) StudyArterioscler Thromb Vasc Biol20082881549155518535285
   PubMed Web of Science ®Google Scholar
• LoriaCMLiuKLewisCEEarly adult risk factor levels and subsequent coronary artery calcification: the CARDIA studyJ Am Coll Cardiol200749202013202017512357
   PubMed Web of Science ®Google Scholar
• CarrJJNelsonJCWongNDCalcified coronary artery plaque measurement with cardiac ct in population-based studies: standardized protocol of Multi-Ethnic Study of Atherosclerosis (MESA) and Coronary Artery Risk Development in Young Adults (CARDIA) StudyRadiology20052341354315618373
   PubMed Web of Science ®Google Scholar
• BildDEBluemkeDABurkeGLMulti-ethnic study of atherosclerosis: objectives and designAm J Epidemiol2002156987188112397006
   PubMed Web of Science ®Google Scholar
• FolsomARKronmalRADetranoRCCoronary artery calcification compared with carotid intima-media thickness in the prediction of cardiovascular disease incidence: the Multi-Ethnic Study of Atherosclerosis (MESA)Arch Intern Med2008168121333133918574091
   PubMed Web of Science ®Google Scholar
• PankajGPRajuPSondejERodriguesEDavisGUse of the Joint British Society cardiovascular risk calculator before initiating statins for primary prevention in hospital medicine: experience from a large university teaching hospitalInt J Gen Med2010337938221189835
   PubMedGoogle Scholar
• BlahaMNasirKDeFilippisAAssociation between hsCRP ≥ 2, Coronary Calcium, and Adverse Events – Implications for the JUPITER Population in the Multi-Ethnic Study of Atherosclerosis (MESA)American Heart Association Scientific Sessions11172010 Abstract 12825. Summary available at: http://www.theheart.org/article/1154871.do.
   Google Scholar
• RothGAFinhSDMokdadAHAekplakornWHasegawaeTLimSSHigh total serum cholesterol, medication coverage and therapeutic control: an analysis of national health examination survey data from eight countriesBull World Health Organ20118929210121346920
   PubMed Web of Science ®Google Scholar
• MinJKLinFYGidsegDSDeterminants of coronary calcium conversion among patients with a normal coronary calcium scan: what is the “warranty period” for remaining normal?J Am Coll Cardiol201055111110111720223365
   PubMed Web of Science ®Google Scholar
• KimKPEinsteinAJde GonzálezABCoronary artery calcification screening: estimated radiation dose and cancer riskArch Intern Med2009169131188119419597067
   PubMedGoogle Scholar
• Smith-BindmanRLipsonJMarcusRDose associated with common computed tomography examinations and the associated lifetime attributable risk of cancerArch Intern Med2009169222078208620008690
   PubMedGoogle Scholar
• RedbergRFCancer risks and radiation exposure from computed tomographic scans: how can we be sure that the benefits outweigh the risks?Arch Intern Med2009169222049205020008685
   PubMedGoogle Scholar
• NambiVBallantyneCM“Risky business”: ten years is not a lifetimeCirculation2009119336236419171864
   PubMed Web of Science ®Google Scholar
• NambiVChamblessLFolsomARAre all patients considered “low risk” for coronary heart disease really low risk? An analysis from the Atherosclerosis Risk in Communities (ARIC) StudyCirculation2008118Suppl 2S1125
   Google Scholar
• NissenSETuzcuEMSchoenhagenPEffect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: a randomized controlled trialJAMA200429191071108014996776
   PubMed Web of Science ®Google Scholar
• NissenSENichollsSJSipahiIEffect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trialJAMA2006295131556156516533939
   PubMed Web of Science ®Google Scholar
• ArtinianNTFletcherGJMozaffarianDon behalf of the American Heart Association Prevention Committee of the Council on Cardiovascular NursingInterventions to promote physical activity and dietary lifestyle changes for cardiovascular risk factor reduction in adults: a scientific statement from the American Heart AssociationCirculation2010122440644120625115
   PubMed Web of Science ®Google Scholar
• YancyCWTransformation of cardiovascular health: presidential address at the American Heart Association 2009 scientific sessionsCirculation2010121252773277620585022
   PubMed Web of Science ®Google Scholar
• BaigentCKeechAKearneyPMCholesterol Treatment Trialists’ (CTT) CollaboratorsEfficacy and safety of cholesterol-lowering treatmentLancet200536694931267127816214597
   PubMed Web of Science ®Google Scholar
• SaelyCHDrexelHHuberKHigh-dose statin therapy for high-risk patientsHerz (Hochdosierte Statintherapie für kardiovaskuläre Risikopatienten)2010357497502
   Google Scholar
• CheungBMLamKSIs intensive LDL-cholesterol lowering beneficial and safe?Lancet201037697531622162421067806
   PubMed Web of Science ®Google Scholar
• NissenSThe “fiction” of primary prevention: role of IVUS in identifying early atherosclerosis4232004 Available at: http://www.theheart.org/article/216595.do. Accessed March 24, 2011.
   Google Scholar
• NissenSEYockPIntravascular ultrasound: novel pathophysiological insights and current clinical applicationsCirculation2001103460461611157729
   PubMed Web of Science ®Google Scholar
• NichollsSJHsuAWolskiKIntravascular ultrasound-derived measures of coronary atherosclerotic plaque burden and clinical outcomeJ Am Coll Cardiol201055212399240720488313
   PubMed Web of Science ®Google Scholar
• DeMariaANNarulaJMahmudETsimikasSImaging vulnerable plaque by ultrasoundJ Am Coll Cardiol200647Suppl 8C32C3916631508
   PubMed Web of Science ®Google Scholar
• MaeharaAMintzGSCristeaEEven after percutaneous coronary intervention of angiographically significant lesions, IVUS-defined high-grade stenoses are common. A baseline IVUS analysis from The Prospect TrialJ Am Coll Cardiol201055A204.E1921
   Google Scholar
• BriguoriCTobisJNishidaTDiscrepancy between angiography and intravascular ultrasound when analysing small coronary arteriesEur Heart J200223324725411792140
   PubMed Web of Science ®Google Scholar
• BallantyneCMRaichlenJSNichollsSASTEROID InvestigatorsEffect of rosuvastatin therapy on coronary artery stenoses assessed by quantitative coronary angiography: a study to evaluate the effect of rosuvastatin on intravascular ultrasound-derived coronary atheroma burdenCirculation2008117192458246618378607
   PubMed Web of Science ®Google Scholar
• BezerraHGCostaMAGuagliumiGRollinsAMSimonDIIntracoronary optical coherence tomography: a comprehensive review: clinical and research applicationsJACC Cardiovasc Interv20092111035104619926041
   PubMed Web of Science ®Google Scholar
• KuboTImanishiTKashiwagiMMultiple coronary lesion instability in patients with acute myocardial infarction as determined by optical coherence tomographyAm J Cardiol2010105331832220102942
   PubMed Web of Science ®Google Scholar
• YamamotoTLuCRyanROA Two-step binding model of PCSK9 Interaction with the low density lipoprotein receptorJ Biol Chem201128675464547021149300
   PubMed Web of Science ®Google Scholar
• HortonJDCohenJCHobbsHHPCSK9: a convertase that coordinates LDL catabolismJ Lipid Res200950SupplS172S17719020338
   PubMed Web of Science ®Google Scholar
• CohenJCBoerwinkleEMosleyTHJrHobbsHHSequence variations in PCSK9, low LDL, and protection against coronary heart diseaseN Engl J Med2006354121264127216554528
   PubMed Web of Science ®Google Scholar
• BennMNordestgaardBGGrandePSchnohrPTybjærg-HansenAPCSK9 R46L, low-density lipoprotein cholesterol levels, and risk of ischemic heart disease: 3 independent studies and meta-analysesJ Am Coll Cardiol201055252833284220579540
   PubMed Web of Science ®Google Scholar
• AbifadelMVarretMRabesJPMutations in PCSK9 cause autosomal dominant hypercholesterolemiaNat Genet200334215415612730697
   PubMed Web of Science ®Google Scholar
• Myocardial Infarction Genetics Consortium Proprotein convertase subtilisin/kexin type 9 (PCSK9) missense variant is reproducibly associated with early-onset myocardial infarction in >1500 cases and 1500 controls (abstr)Circulation2007116II806
   Google Scholar
• SteinbergDEarlier intervention in the management of hypercholesterolemia: what are we waiting for?J Am Coll Cardiol201056862762920705219
   PubMed Web of Science ®Google Scholar
• KonesRRecent advances in the management of chronic stable angina. II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularizationVasc Health Risk Manag2010674977420859545
   PubMedGoogle Scholar
• DomanskiMJPrimary prevention of coronary artery diseaseN Engl J Med2007357151543154517928603
   PubMed Web of Science ®Google Scholar
• RedbergRBenjaminEJBittnerVACCF/AHA 2009 Performance measures for primary prevention of cardiovascular disease in adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Performance Measures (Writing Committee to Develop Performance Measures for Primary Prevention of Cardiovascular Disease) developed in collaboration with the American Academy of Family Physicians; American Association of Cardiovascular and Pulmonary Rehabilitation; and Preventive Cardiovascular Nurses Association: endorsed by the American College of Preventive Medicine, American College of Sports Medicine, and Society for Women’s Health ResearchJ Am Coll Cardiol200954141364140519778679
   PubMed Web of Science ®Google Scholar
• ForresterJSRedefining normal low-density lipoprotein cholesterol: a strategy to unseat coronary disease as the nation’s leading killerJ Am Coll Cardiol201056863063620705220
   PubMed Web of Science ®Google Scholar
• DeMazumderDHasanRKBlumenthalRSMichosEDJonesSShould statin therapy be allocated on the basis of global risk or on the basis of randomized trial evidence?Am J Cardiol2010106690590920816135
   PubMed Web of Science ®Google Scholar
• NambiVBallantyneCMUtility of statin therapy using high-sensitivity C-reactive protein as an indicator of coronary heart disease riskCurr Atheroscler Rep200571222815683598
   PubMedGoogle Scholar
• RidkerPMHigh-sensitivity C-reactive protein and cardiovascular risk: rationale for screening and primary preventionAm J Cardiol2003924B17K22K
   PubMed Web of Science ®Google Scholar
• MähönenMSMcElduffPDobsonAJKuulasmaaKAEvansAEfor the WHO MONICA ProjectCurrent smoking and the risk of non-fatal myocardial infarction in the WHO MONICA Project populationsTob Control200413324425015333879
   PubMed Web of Science ®Google Scholar
• BakhruAErlingerTPSmoking cessation and cardiovasacular disease risk factors: Results from the third National Health and Nutrition Examination SurveyPLoS Med200526e16015974805
   PubMed Web of Science ®Google Scholar
• YusufSLonnEBoschJLipid lowering for primary preventionLancet200937396701152115519345816
   PubMed Web of Science ®Google Scholar
• BurtVLCutlerJAHigginsMTrends in the prevalence, awareness, treatment, and control of hypertension in the adult US population. Data from the health examination surveys, 1960 to 1991Hypertension199526160697607734
   PubMed Web of Science ®Google Scholar
• DolanEStantonAThijsLSuperiority of ambulatory over clinic blood pressure measurement in predicting mortality: the Dublin outcome studyHypertension200546115616115939805
   PubMed Web of Science ®Google Scholar
• YehRWSidneySChandraMSorelMSelbyJGoASPopulation trends in the incidence and outcomes of acute myocardial infarctionN Engl J Med2010362232155216520558366
   PubMed Web of Science ®Google Scholar
• BrownJRO’ConnorGTCoronary heart disease and prevention in the United StatesN Eng J Med20103622321502153
   Web of Science ®Google Scholar
• Garcia-GarciaHMCostaMASerruysPWImaging of coronary atherosclerosis: intravascular ultrasoundEur Heart J201031202456246920823109
   PubMed Web of Science ®Google Scholar
• SipahiINichollsSJTuzcuEMNissenSECoronary atherosclerosis can regress with very intensive statin therapyCleve Clin J Med2006731093794417044319
   PubMed Web of Science ®Google Scholar
• MackWJXiangMSelzerRHHodisHNSerial quantitative coronary angiography and coronary eventsAm Heart J2000139699399910827379
   PubMed Web of Science ®Google Scholar
• BuchwaldHMattsJPFitchLLfor the Program on the Surgical Control of the Hyperlipidemias (POSCH) GroupChanges in sequential coronary arteriograms and subsequent coronary eventsJAMA199226811142914331512911
   PubMed Web of Science ®Google Scholar
• PetronioASAmorosoGLimbrunoUSimvastatin does not inhibit intimal hyperplasia and restenosis but promotes plaque regression in normocholesterolemic patients undergoing coronary stenting: a randomized study with intravascular ultrasoundAm Heart J2005149352052615864242
   PubMed Web of Science ®Google Scholar
• TaniSWatanabeIAnazawaTEffect of pravastatin on malondialdehyde-modified low-density lipoprotein levels and coronary plaque regression as determined by three-dimensional intravascular ultrasoundAm J Cardiol20059681089109416214443
   PubMed Web of Science ®Google Scholar
• TakashimaHOzakiYYasukawaTImpact of lipid-lowering therapy with pitavastatin, a new HMG-CoA reductase inhibitor, on regression of coronary atherosclerotic plaqueCirc J200771111678168417965484
   PubMed Web of Science ®Google Scholar
• TakayamaTHiroTYamagishiMEffect of rosuvastatin on coronary atheroma in stable coronary artery disease: multicenter coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS)Circ J200973112110211719801853
   PubMed Web of Science ®Google Scholar
• HiroTKimuraTMorimotoTEffect of intensive statin therapy on regression of coronary atherosclerosis in patients with acute coronary syndrome: a multicenter randomized trial evaluated by volumetric intra-vascular ultrasound using pitavastatin versus atorvastatin (JAPAN-ACS [Japan assessment of pitavastatin and atorvastatin in acute coronary syndrome] study)J Am Coll Cardiol200954429330219608026
   PubMed Web of Science ®Google Scholar
• HirayamaASaitoSUedaYQualitative and quantitative changes in coronary plaque associated with atorvastatin therapyCirc J200973471872519225206
   PubMed Web of Science ®Google Scholar
• InoueKMotoyamaSSaraiMSerial coronary CT angiography–verified changes in plaque characteristics as an end point: evaluation of effect of statin interventionJACC Cardiovasc Imaging20103769169820633846
   PubMed Web of Science ®Google Scholar
• StoneGWMaeharaALanskyAJfor the PROSPECT InvestigatorsA prospective natural-history study of coronary atherosclerosisN Engl J Med2011364322623521247313
   PubMed Web of Science ®Google Scholar
• BayturanOKapadiaSNichollsSJClinical predictors of plaque progression despite very low levels of low-density lipoprotein cholesterolJ Am Coll Cardiol201055242736274220538166
   PubMed Web of Science ®Google Scholar
• RidkerPMDanielsonEFonsecaFAReduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trialLancet200937396701175118219329177
   PubMed Web of Science ®Google Scholar
• Van der ZijlNJMuskietHATushuizenMEC-reactive protein mediates the association of liver fat and carotid intima–media thickness in healthy men and men with the metabolic syndrome and/or uncomplicated type 2 diabetesDiab Met Syndr Clin Res Rev201043160164
   Google Scholar
• JBS 2: Joint British Societies’ guidelines on prevention of cardiovascular disease in clinical practiceHeart200591Suppl 5v1v5216365341
   PubMed Web of Science ®Google Scholar
• ChobanianAVBakrisGLBlackHRSeventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood PressureHypertension20034261206125214656957
   PubMed Web of Science ®Google Scholar
• NHS National Institute for Health and Clinical ExcellenceStatins for the prevention of cardiovascular events Technology appraisal 94,1252006 Available at http://guidance.nice.org.uk/TA94/Guidance/pdf/English. Accessed on March 24, 2011.
   Google Scholar
• NHS National Institute for Health and Clinical ExcellencePrevention of Cardiovascular Disease at Population Level NICE public health guidance 25.62010 Available at: http://www.nice.org.uk/nicemedia/live/13024/49273/49273.pdf. Accessed March 24, 2011.
   Google Scholar
• Royal College of General PractitionersLipid modification: cardiovascular risk assessment and the modification of blood lipids for the primary and secondary prevention of cardiovascular disease NICE Clinical guideline 67.LondonRCGP2008 Reissued March, 2010. Available at: http://www.nice.org.uk/guidance/index.jsp?action=byID&o=11982. Accessed March 24, 2011.
   Google Scholar
• GrundySMCleemanJIMerzCNThe Coordinating Committee of the National Cholesterol Education ProgramImplications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III GuidelinesCirculation2004110222723915249516
   PubMed Web of Science ®Google Scholar
• BeriAContractorTKhasnisAThakurRStatins and the reduction of sudden cardiac death: antiarrhythmic or anti-ischemic effect?Am J Cardiovasc Drugs201010315516420524717
   PubMed Web of Science ®Google Scholar
• WardSLloyd JonesMPandorAA systematic review and economic evaluation of statins for the prevention of coronary eventsHealth Technol Assess200711141160
   Web of Science ®Google Scholar
• ThavendiranathanPBagaiABrookhartMAChoudhryNKPrimary prevention of cardiovascular diseases with statin therapy: a meta-analysis of randomized controlled trialsArch Intern Med2006166212307231317130382
   PubMedGoogle Scholar
• MillsEJRachlisBWuPDevereauxPJAroraPPerriDPrimary prevention of cardiovascular mortality and events with statin treatments: a network meta-analysis involving more than 65,000 patientsJ Am Coll Cardiol200852221769178119022156
   PubMed Web of Science ®Google Scholar
• BrugtsJJYetginTHoeksSEThe benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trialsBMJ2009338b237619567909
   PubMed Web of Science ®Google Scholar
• RayKKSeshasaiSRKErqouSStatins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65,229 participantsArch Intern Med2010170121024103120585067
   PubMedGoogle Scholar
• PasternakRCSmithSCJrBairey-MerzCNGrundySMCleemanJILenfantCACC/AHA/NHLBI Clinical advisory on the use and safety of statinsJ Am Coll Cardiol200240356757212142128
   PubMed Web of Science ®Google Scholar
• GrundySMCleemanJIMerzCNNational Heart, Lung, and Blood InstituteAmerican College of Cardiology FoundationAmerican Heart AssociationImplications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelinesCirculation2004110222723915249516
   PubMed Web of Science ®Google Scholar
• BukkapatnamRNGablerNBLewisWRStatins for primary prevention of cardiovascular mortality in women: a systematic review and meta-analysisPrev Cardiol2010132849020377811
   PubMedGoogle Scholar
• NakamuraHArakawaKItakuraHMEGA Study GroupPrimary prevention of cardiovascular disease with pravastatin in Japan (MEGA Study): a prospective randomized controlled trialLancet200636895421155116317011942
   PubMed Web of Science ®Google Scholar
• NakamuraHPrimary prevention of cardiovascular diseases among hypercholesterolemic Japanese with a low dose of pravastatinAtheroscler Suppl200782131717586102
   PubMed Web of Science ®Google Scholar
• TaylorFWardKMooreTHMStatins for the primary prevention of cardiovascular diseaseCochrane Database Syst Rev20111CD00481621249663
   PubMed Web of Science ®Google Scholar
• GottoAMImproving lipid goal attainment. is it enough?Circulation200912013519546383
   PubMed Web of Science ®Google Scholar
• PletcherMJHulleySBStatin therapy in young adults: ready for prime time?J Am Coll Cardiol201056863764020705221
   PubMed Web of Science ®Google Scholar
• CooperAO’FlynnNRisk assessment and lipid modification for primary and secondary prevention of cardiovascular disease: summary of NICE guidanceBMJ200833676551246124818511800
   PubMed Web of Science ®Google Scholar
• LeeKKCiprianoLEOwensDKGoASHlatkyMACost-effectiveness of using high-sensitivity C-reactive protein to identify intermediate-and low-cardiovascular-risk individuals for statin therapyCirculation2010122151478148720876434
   PubMed Web of Science ®Google Scholar
• VaklavasCChatzizisisYSZiakasAZamboulisCGiannoglouGDMolecular basis of statin-associated myopathyAtherosclerosis20092021182818585718
   PubMed Web of Science ®Google Scholar
• MasEMoriTACoenzyme Q10 and statin myalgia: what is the evidence?Curr Atheroscler Rep201012640741320725809
   PubMed Web of Science ®Google Scholar
• VandenbergBFRobinsonJManagement of the patient with statin intoleranceCurr Atheroscler Rep2010121485720425271
   PubMed Web of Science ®Google Scholar
• ThompsonPDClarksonPMRosensonRSNational Lipid Association Statin Safety Task Force Muscle Safety Expert PanelAn assessment of statin safety by muscle expertsAm J Cardiol2006978A69C76C
   PubMed Web of Science ®Google Scholar
• DeedwaniaPStonePHBairey MerzCNEffects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE)Circulation2007115670070717283260
   PubMed Web of Science ®Google Scholar
• GottoAMJrStatin therapy and the elderly: SAGE Advice?Circulation2007115668168317296867
   PubMed Web of Science ®Google Scholar
• GolombBStatin adverse effects: implications for the elderlyGeriatric Times2004541820
   Google Scholar
• NicholsGANagSChanWIntensity of lipid-lowering therapy and low-density lipoprotein cholesterol goal attainment among the elderly before and after the 2004 National Cholesterol Education Program Adult Treatment Panel III updateAm Heart J2007154355456017719305
   PubMed Web of Science ®Google Scholar
• MarooBPLavieCJMilaniRVEfficacy and safety of intensive statin therapy in the elderlyAm J Geriatr Cardiol20081729210018326948
   PubMedGoogle Scholar
• WengerNKLewisSJUse of Statin Therapy to Reduce Cardiovascular Risk in Older PatientsCurr Gerontol Geriatr Res2010915296
   Google Scholar
• LongSBBlahaMJBlumenthalRSMichosEDClinical utility of rosuvastatin and other statins for cardiovascular risk reduction among the elderlyClin Interv Aging20116273521472089
   PubMed Web of Science ®Google Scholar
• PletcherMJCoxsonPGDoes age modify effectiveness of statin therapy in coronary artery disease?Ann Intern Med20101521282520547915
   PubMed Web of Science ®Google Scholar
• LewingtonSWhitlockGClarkeRProspective Studies CollaborationBlood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55,000 vascular deathsLancet200737096021829183918061058
   PubMed Web of Science ®Google Scholar
• PletcherMJLazarLBibbins-DomingoKComparing impact and cost effectiveness of primary prevention strategies for lipid-loweringAnn Intern Med2009150424325419221376
   PubMed Web of Science ®Google Scholar
• HaywardRADoes age modify effectiveness of statin therapy in coronary artery disease?Ann Intern Med20101521282582620547915
   PubMed Web of Science ®Google Scholar
• GlynnRJKoenigWNordestgaardBGShepherdJRidkerPMRosuvastatin for primary prevention in older persons with elevated C-reactive protein and low to average low-density lipoprotein cholesterol levels: exploratory analysis of a randomized trialAnn Intern Med2010152848849620404379
   PubMed Web of Science ®Google Scholar
• ZiemanSJOuyangPStatins for primary prevention in older adults: who is high risk, who is old, and what denotes primary prevention?Ann Int Med2010152852853020404384
   PubMed Web of Science ®Google Scholar
• JafferFAO’DonnellCJLarsonMGAge and sex distribution of subclinical aortic atherosclerosis: a magnetic resonance imaging examination of the Framingham Heart StudyArterioscler Thromb Vasc Biol200222584985412006401
   PubMed Web of Science ®Google Scholar
• CannonCPBraunwaldEMcCabeCHIntensive versus moderate lipid lowering with statins after acute coronary syndromesN Engl J Med2004350151495150415007110
   PubMed Web of Science ®Google Scholar
• RayKKCannonCairnsRPROVE IT-TIMI 22 InvestigatorsRelationship between uncontrolled risk factors and C-reactive protein levels in patients receiving standard or intensive statin therapy for acute coronary syndromes in the PROVE IT-TIMI 22 TrialJ Am Coll Cardiol20054681417142416226164
   PubMed Web of Science ®Google Scholar
• MillerMCannonCPMurphySAImpact of triglyceride levels beyond low-density lipoprotein cholesterol after acute coronary syndrome in the PROVE-IT TIMI 22 trialJ Am Coll Cardiol200851772473018279736
   PubMed Web of Science ®Google Scholar
• SacksFMTonkinAMCravenTCoronary heart disease in patients with low LDL-cholesterol: benefit of pravastatin in diabetics and enhanced role for HDL-cholesterol and triglycerides as risk factorsCirculation2002105121424142811914249
   PubMed Web of Science ®Google Scholar
• BarterPGottoAMLaRosaJCHDL cholesterol, very low levels of LDL cholesterol, and cardiovascular eventsN Engl J Med2007357131301131017898099
   PubMed Web of Science ®Google Scholar
• ArsenaultBJRanaJSStroesESGBeyond low-density lipoprotein cholesterol: respective contributions of non– high density lipoprotein cholesterol levels, triglycerides, and the total cholesterol/high-density lipoprotein cholesterol ratio to coronary heart disease risk in apparently healthy men and womenJ Am Coll Cardiol2010551354120117361
   PubMed Web of Science ®Google Scholar
• CareyVJBishopLLaranjoNHarshfieldBJKwiatCSacksFMContribution of high plasma triglycerides and low high-density lipoprotein cholesterol to residual risk of coronary heart disease after establishment of low-density lipoprotein cholesterol controlAm J Cardiol2010106675776320816113
   PubMed Web of Science ®Google Scholar
• Núñez-CortésJMJuan MontoyaJP-BSalasXPEstudio REALIST (REsiduAl risk, LIpids and Standard Therapies): Un análisis del Riesgo Residual dependiente del perfil lipídico en el síndrome coronario agudoEndocrinol Nutr2011581384721208833
   PubMedGoogle Scholar
• NeilCENicklasTARelationship Between Diet/Physical Activity and HealthAm J Lifestyle Med200716457481
   Google Scholar
• StevensJMcClainJETruesdaleJPCommentary: Obesity claims and controversiesInt J Epidemiol2006351777816339595
   PubMed Web of Science ®Google Scholar
• ChamberlainJFrancisSBrookesZInterleukin-1 regulates multiple atherogenic mechanisms in response to fat feedingPLoS ONE200944e507319347044
   PubMed Web of Science ®Google Scholar
• LamonBDHajjarDPInflammation at the molecular interface of atherogenesis: an anthropological journeyAm J Pathol200817351253126418948435
   PubMed Web of Science ®Google Scholar
• McLaughlinTAbbasiFLamendolaCReavenGHeterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes mellitus in obese individuals: effect of differences in insulin sensitivityArch Intern Med2007167764264817420421
   PubMedGoogle Scholar
• GoldsteinBJScaliaRAdiponectin: a novel adipokine linking adipocytes and vascular functionJ Clin Endocrinol Metab20048962563256815181024
   PubMed Web of Science ®Google Scholar
• BrayGAMedical consequences of obesityJ Clin Endocrinol Metab20048962583258915181027
   PubMed Web of Science ®Google Scholar
• KershawEEFlierJSAdipose tissue as an endocrine organJ Clin Endocrinol Metab20048962548255615181022
   PubMed Web of Science ®Google Scholar
• ZiemkeFMantzorosCSAdiponectin in insulin resistance: lessons from translational researchAm J Clin Nutr2010911258S261S19906806
   PubMed Web of Science ®Google Scholar
• HajerGRvan HaeftenTWVisserenFLJAdipose tissue dysfunction in obesity, diabetes, and vascular diseasesEur Heart J200829242959297118775919
   PubMed Web of Science ®Google Scholar
• BodenGEndoplasmic reticulum stress: another link between obesity and insulin resistance/inflammation?Diabetes200958351851919246600
   PubMed Web of Science ®Google Scholar
• RasouliNKernPAAdipocytokines and the Metabolic Complications of ObesityJ Clin Endocrinol Metab20089311 Supp1s64s7318987272
   PubMed Web of Science ®Google Scholar
• ZhangHZhangCAdipose “talks’ to distant organs to regulate insulin sensitivity and vascular functionObesity201018112071207620395945
   PubMed Web of Science ®Google Scholar
• BermanDSChengVYDeyDNot all body fat weighs equally in the acceleration of coronary artery diseaseJ Am Coll Cardiol Img201039918920
   Web of Science ®Google Scholar
• OhashiNYamamotoHHoriguchiJAssociation between visceral adipose tissue area and coronary plaque morphology assessed by ct angiographyJACC Cardiovasc Imaging20103990891720846624
   PubMed Web of Science ®Google Scholar
• HsiaJMacFadyenJGMonyakJRidkerPMCardiovascular event reduction and adverse events among subjects attaining low-density lipoprotein cholesterol 50 mg/dl with rosuvastatinJ Am Coll Cardiol201157161666167521492764
   PubMed Web of Science ®Google Scholar
• McMurrayJJHolmanRRHaffnerSMThe NAVIGATOR Study GroupEffect of valsartan on the incidence of diabetes and cardiovascular eventsN Engl J Med2010362161477149020228403
   PubMed Web of Science ®Google Scholar
• HolmanRRHaffnerSMMcMurrayJJThe NAVIGATOR Study GroupEffect of nateglinide on the incidence of diabetes and cardiovascular eventsN Engl J Med2010362161463147620228402
   PubMed Web of Science ®Google Scholar
• GinsbergHNElamMBLovatoLCfor The ACCORD Study GroupEffects of Combination Lipid Therapy in Type 2 Diabetes MellitusN Engl J Med2010362171563157420228404
   PubMed Web of Science ®Google Scholar
• NilssonPMACCORD and Risk-Factor Control in Type 2 DiabetesN Eng J Med20103621716281630
   Web of Science ®Google Scholar
• NichollsSJLundmanPTardifJ-CDiabetic dyslipidemia: extending the target beyond LDL cholesterolEur J Cardiovasc Prev Rehabil201017suppl 1s20s2420489416
   PubMedGoogle Scholar
• HermansMPFruchaartJ-CReducing residual vascular risk in patients with atherogenic dyslipidemia: Where do we go from here?Clin Lipidol201056811826
   Web of Science ®Google Scholar
• GordonDJProbstfieldJLGarrisonRJHigh-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studiesCirculation19897918152642759
   PubMed Web of Science ®Google Scholar
• NichollsSJTuzcuEMSipaghiIStatins, high-density lipoprotein cholesterol, and regression of coronary atherosclerosisJAMA2007297549950817284700
   PubMed Web of Science ®Google Scholar
• BrownBZhaoXCheungMShould both HDL-C and LDL-C be targets for lipid therapy? A review of current evidenceJ Clin Lipidol200711889421291671
   PubMed Web of Science ®Google Scholar
• GhandehariHKamal-BahlSWongNDPrevalence and extent of dyslipidemia and recommended lipid levels in US adults with and without cardiovascular comorbidities: the National Health and Nutrition Examination Survey 2003–2004Am Heart J2008156111211918585505
   PubMed Web of Science ®Google Scholar
• SachdevaACannonCPDeedwaniaPCLipid levels in patients hospitalized with coronary artery disease: an analysis of 136,905 hospitalizations in Get With The GuidelinesAm Heart J20091571111117.e219081406
   PubMed Web of Science ®Google Scholar
• SharrettARBallantyneCMCoadySACoronary heart disease prediction from lipoprotein cholesterol levels, triglycerides, lipoprotein(a), apolipoproteins A-I and B, and HDL density subfractions: the Atherosclerosis Risk in Communities (ARIC) StudyCirculation2001104101108111311535564
   PubMed Web of Science ®Google Scholar
• Emerging Risk Factors CollaborationMajor lipids, apolipoproteins, and risk of vascular diseaseJAMA2009302181993200019903920
   PubMed Web of Science ®Google Scholar
• BrielMFerreira-GonzalezIYouJJAssociation between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysisBMJ2009338b9219221140
   PubMed Web of Science ®Google Scholar
• GottoAMWhitneyESteinEARelation between baseline and on-treatment lipid parameters and first acute major coronary events in the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)Circulation2000101547748410662743
   PubMed Web of Science ®Google Scholar
• JonesPHDavidsonMHSteinEAComparison of the efficacy and safety of rosuvastatin versus atorvastatin, simvastatin, and pravastatin across doses (STELLAR* Trial)Am J Cardiol200392215216012860216
   PubMed Web of Science ®Google Scholar
• JonesPHHunninghakeDBFerdinandKCEffects of rosuva-statin versus atorvastatin, simvastatin, and pravastatin on non-high-density lipoprotein cholesterol, apolipoproteins, and lipid ratios in patients with hypercholesterolemia: additional results from the STELLAR trialClin Ther20042691388139915531001
   PubMed Web of Science ®Google Scholar
• NegiSBallantyneCMInsights from recent meta-analysis: role of high-density lipoprotein cholesterol in reducing cardiovascular events and rates of atherosclerotic disease progressionJ Clin Lipidol20104536537021122680
   PubMed Web of Science ®Google Scholar
• CRESTOR Athero Imaging Head to Head IVUS Study (SATURN)National Institutes of Health2512010 Available at: http://clinicaltrials.gov/ct2/show/NCT00620542. Accessed March 24, 2011.
   Google Scholar
• SaleemTSMRaniPVSGauthamanKHigh-density lipoproteins: a novel therapeutic target for cardiovascular diseaseRes Reports Clin Cardiol2011216
   Google Scholar
• VaisarTPennathurSGreenPSShotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDLJ Clin Invest2007117374675617332893
   PubMed Web of Science ®Google Scholar
• GreeneDJSkeggsJWMortonREElevated triglyceride content diminishes the capacity of high density lipoprotein to deliver cholesteryl esters via the scavenger receptor class B type I (SR-BI)J Biol Chem200127674804481111067853
   PubMed Web of Science ®Google Scholar
• SaddarSMineoCShaulPWSignaling by the high-affinity hdl receptor scavenger receptor B type IArterioscler Thromb Vasc Biol201030214415020089950
   PubMed Web of Science ®Google Scholar
• NavabMReddySTVan LentenBJFogelmanAMHDL and cardiovascular disease: atherogenic and atheroprotective mechanismsNat Rev Cardiol20118422223221304474
   PubMed Web of Science ®Google Scholar
• BrewerHBJrSantamarina-FojoSNew insights into the role of the adenosine triphosphate-binding cassette transporters in high-density lipoprotein metabolism and reverse cholesterol transportAm J Cardiol2003917A3E11E
   Web of Science ®Google Scholar
• NavabMShechterIAnantharamaiahGMReddySTVan LentenBJFogelmanAMstructure and function of HDL mimeticsArterioscler Thromb Vasc Biol201030216416819608977
   PubMed Web of Science ®Google Scholar
• MassonDJiangXCLagrostLTallARThe role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesisJ Lipid Res200950SupplS201S20619023137
   PubMed Web of Science ®Google Scholar
• KheraAVCuchelMMargarita de la Llera-MoyaCholesterol efflux capacity, high-density lipoprotein function, and atherosclerosisN Engl J Med2011364212713521226578
   PubMed Web of Science ®Google Scholar
• HeineckeJHDL and Cardiovascular-Disease risk – time for a new approach?N Engl J Med2011364217017121226584
   PubMed Web of Science ®Google Scholar
• RosenblatMAviramMParaoxonases role in the prevention of cardiovascular diseasesBiofactors20093519810419319852
   PubMed Web of Science ®Google Scholar
• GetzGSReardonCAParaoxonase, a cardioprotective enzyme: continuing issuesCurr Opin Lipidol200415326126715166781
   PubMed Web of Science ®Google Scholar
• AndersenRVWittrupHHTybjaerg-HansenASteffensenRSchnohrPNordestgaardBGHepatic lipase mutations, elevated high-density lipoprotein cholesterol, and increased risk of ischemic heart disease: the Copenhagen City Heart StudyJ Am Coll Cardiol200341111972198212798568
   PubMed Web of Science ®Google Scholar
• CorsettiJPZarebaWMossAJRainwaterDLSparksCEElevated HDL is a risk factor for recurrent coronary events in a subgroup of non-diabetic postinfarction patients with hypercholesterolemia and inflammationAtherosclerosis2006187119119716242700
   PubMed Web of Science ®Google Scholar
• DeGomaEMLeeperNJHeidenreichPAClinical significance of high-density lipoprotein cholesterol in patients with low low-density lipoprotein cholesterolJ Am Coll Cardiol2008511495518174036
   PubMed Web of Science ®Google Scholar
• van der SteegWAHolmeIBoekholdtSMHigh-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular riskJ Am Coll Cardiol200851663464218261682
   PubMed Web of Science ®Google Scholar
• CorsettiJPGansevoortRTSparksCEDullaartRPFHDL inflammation reduces HDL protection against primary cardiac riskEur J Clin Invest201040648348920412290
   PubMed Web of Science ®Google Scholar
• DullaartRPFIncreased coronary heart disease risk determined by high high-density lipoprotein cholesterol and c-reactive protein: modulation by variation in the CETP geneArterioscler Thromb Vasc Biol20103081502150320631348
   PubMed Web of Science ®Google Scholar
• RossouwJEAndersonGLPrenticeRLWriting Group for the Women’s Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trialJAMA2002288332133312117397
   PubMed Web of Science ®Google Scholar
• DavidsonWSSilvaRAGDChantepieSLagorWRChapmanMJKontushAProteomic analysis of defined HDL subpopulations reveals particle-specific protein clusters: relevance to antioxidative functionArterioscler Thromb Vasc Biol200929687087619325143
   PubMed Web of Science ®Google Scholar
• YanceyPGBortnickAEKellner-WeibelGImportance of different pathways of cellular cholesterol effluxArterioscler Thromb Vasc Biol2003123571271912615688
   PubMed Web of Science ®Google Scholar
• KontushAChapmanMJAntiatherogenic small, dense HDL-guardian angel of the arterial wall?Nat Clin Pract Cardiovasc Med20063314415316505860
   PubMedGoogle Scholar
• ZhengLNukunaBBrennanM-LApolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular diseaseJ Clin Invest2004114452954115314690
   PubMed Web of Science ®Google Scholar
• SacksFMAlaupovicPMoyeLAVLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trialCirculation2000102161886189211034934
   PubMed Web of Science ®Google Scholar
• ShaoBOdaMNOramJFHeineckeJWMyeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoproteinChem Res Toxicol201023344745420043647
   PubMed Web of Science ®Google Scholar
• NorataGDPirilloACatapanoALModified HDL: biological and physiopathological consequencesNutr Metabol Cardiovasc Dis2006165371386
   Web of Science ®Google Scholar
• KhovidhunkitWKimMSMemonRAEffects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the hostJ Lipid Res20044571169119615102878
   PubMed Web of Science ®Google Scholar
• EsteveERicartWFernandez-RealJMDyslipidemia and inflammation: an evolutionary conserved mechanismClin Nutr2005241163115681098
   PubMed Web of Science ®Google Scholar
• NavabMAnantharamaiahGMReddySTThe oxidation hypothesis of atherogenesis: the role of oxidized phospholipids and HDLJ Lipid Res2004456993100715060092
   PubMed Web of Science ®Google Scholar
• AnsellBJNavabMHamaSInflammatory/antiinflammatory properties of high-density lipoprotein distinguish patients from control subjects better than high-density lipoprotein cholesterol levels and are favorably affected by simvastatin treatmentCirculation2003108222751275614638544
   PubMed Web of Science ®Google Scholar
• BriffaTGHobbsMSTonkinAPopulation trends of recurrent coronary heart disease event rates remain highCirc Cardiovasc Qual Outcomes20104110711321139089
   PubMed Web of Science ®Google Scholar
• TallARBreslowJLRubinEMGenetic disorders affecting plasma high-density lipoproteins Available at: http://www.ommbid.com/OMMBID/the_online_metabolic_and_molecular_bases_of_inherited_disease/b/abstract/part12/ch121. Accessed March 24, 2011.
   Google Scholar
• AnsellBJTargeting the anti-inflammatory effects of high-density lipoproteinAm J Cardiol200710011An3918047850
   PubMed Web of Science ®Google Scholar
• GreenPSVaisarTPennathurSCombined statin and niacin therapy remodels the high-density lipoprotein proteomeCirculation2008118121259126718765395
   PubMed Web of Science ®Google Scholar
• SorrentinoSABeslerCRohrerLEndothelial-vasoprotective effects of high-density lipoprotein are impaired in patients with type 2 diabetes mellitus but are improved after extended-release niacin therapyCirculation2010121111012220026785
   PubMed Web of Science ®Google Scholar
• HeslopCLFrohlichJJHillJSMyeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiographyJ Am Coll Cardiol201055111102110920223364
   PubMed Web of Science ®Google Scholar
• SinghUDevarajSJialalIC-reactive protein stimulates myeloperoxidase release from polymorphonuclear cells and monocytes: implications for acute coronary syndromesClin Chem200955236136419074520
   PubMed Web of Science ®Google Scholar
• RashidSWatanabeTSakaueTLewisGFMechanisms of HDL lowering in insulin resistant, hypertriglyceridemic states: the combined effect of HDL triglyceride enrichment and elevated hepatic lipase activityClin Biochem200336642142912951168
   PubMed Web of Science ®Google Scholar
• XiaoCWatanabeTZhangYEnhanced cellular uptake of remnant high-density lipoprotein particles: a mechanism for high-density lipoprotein lowering in insulin resistance and hypertriglyceridemiaCirc Res2008103215916618556574
   PubMed Web of Science ®Google Scholar
• BrownRJRaderDJWhen HDL Gets FatCirc Res2008103213113218635830
   PubMed Web of Science ®Google Scholar
• HanselBGiralPNobecourtEMetabolic syndrome is associated with elevated oxidative stress and dysfunctional dense high-density lipoprotein particles displaying impaired antioxidative activityJ Clin Endocrinol Metab200489104963497115472192
   PubMed Web of Science ®Google Scholar
• NobecourtEJacqueminetSHanselBDefective antioxidative activity of small, dense HDL particles in type 2 diabetes: relationship to elevated oxidative stress and hyperglycemiaDiabetologia20054835293815729582
   PubMed Web of Science ®Google Scholar
• KontushAChapmanMJFunctionally defective high-density lipoprotein: a new therapeutic target at the crossroads of dyslipidemia, inflammation, and atherosclerosisPharmacol Rev200658334237416968945
   PubMed Web of Science ®Google Scholar
• GetzGSReardonCAHigh-density lipoprotein function in regulating insulin secretion: possible relevance to metabolic syndromeArterioscler Thromb Vasc Biol20103081497149920631346
   PubMed Web of Science ®Google Scholar
• OksjokiRKovanenPTPentikainenMORole of complement activation in atherosclerosisCurr Opin Lipidol200314547748214501586
   PubMed Web of Science ®Google Scholar
• HeineckeJWThe protein cargo of HDL: Implications for vascular wall biology and therapeuticsJ Clin Lipidol20104537137520975842
   PubMed Web of Science ®Google Scholar
• McGillicuddyFCde la LleraMMHinkleCCInflammation impairs reverse cholesterol transport in vivoCirculation200911981135114519221221
   PubMed Web of Science ®Google Scholar
• KhovidhunkitWMoserAHShigenagaJKGrunfeldCFeingoldKREndotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXRJ Lipid Res20034491728173612777468
   PubMed Web of Science ®Google Scholar
• AnnemaWNijstadNTolleMMyeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A(2)J Lipid Res201051474375420061576
   PubMed Web of Science ®Google Scholar
• InouyeMSilanderKHamalainenEAn immune response network associated with blood lipid levelsPLoS Genet201069e1001113
   PubMed Web of Science ®Google Scholar
• Weissglas-VolkovDPajukantaPGenetic causes of high and low serum HDL-cholesterolJ Lipid Res20105182032205720421590
   PubMed Web of Science ®Google Scholar
• CorsettiJPRyanDRainwaterDLMossAJZarebaWSparksCECholesteryl ester transfer protein polymorphism (TaqIB) associates with risk in postinfarction patients with high C-reactive protein and high-density lipoprotein cholesterol levelsArterioscler Thromb Vasc Biol20103081657166420489166
   PubMed Web of Science ®Google Scholar
• NavabMHamaSYHoughGPSubbanagounderGReddySTFogelmanAMA cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipidsJ Lipid Res20014281308131711483633
   PubMed Web of Science ®Google Scholar
• KarthikeyanGTeoKKIslamSLipid profile, plastma apolipoproteins, and risk of a first myocardial infarction among Asians: an analysis from the INTERHEART studyJ Am Coll Cardiol200953324425319147041
   PubMed Web of Science ®Google Scholar
• DodaniSKaurRReddySReedGLNavabMGeorgeVCan dysfunctional HDL explain high coronary artery disease risk in south Asians?Int J Cardiol2008129112513218255168
   PubMed Web of Science ®Google Scholar
• DodaniSCan conventional risk factors explain excess coronary artery disease risk in south asians: dyslipidemias and dysfunctional high density lipoprotein (HDL)Open Epidemiol J200925562
   Google Scholar
• DasUNA defect in Δ6 and Δ5 desaturases may be a factor in the initiation and progression of insulin resistance, the metabolic syndrome and ischemic heart disease in South AsiansLipids Health Dis2010913021062475
   PubMed Web of Science ®Google Scholar
• ChapmanMJLe GoffWGuerinMKontushACholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitorsEur Heart J201031214916419825813
   PubMed Web of Science ®Google Scholar
• RyeKABursillCALambertGTabetFBarterPJThe metabolism and anti-atherogenic properties of HDLJ Lipid Res200950SupplS195S20019033213
   PubMed Web of Science ®Google Scholar
• TsompanidiEMBrinkmeierMSFotiadouEHGiakoumiSMKypreosKEHDL biogenesis and functions: role of HDL quality and quantity in atherosclerosisAtherosclerosis201020813919595353
   PubMed Web of Science ®Google Scholar
• NatarajanPRayKKCannonCPHigh-density lipoprotein and coronary heart disease: current and future therapiesJ Am Coll Cardiol201055131283129920338488
   PubMed Web of Science ®Google Scholar
• DodaniSGriceDGJoshiSIs HDL function as important as HDL quantity in the coronary artery disease risk assessment?J Clin Lipidol200932707721291795
   PubMed Web of Science ®Google Scholar
• AllaVMManuKMoossATargeting residual risk: the rationale for the use of non-HDL cholesterolSouthern Med J2010103543443720375942
   PubMed Web of Science ®Google Scholar
• BarterPJCaulfieldMErikssonMEffects of torcetrapib in patients at high risk for coronary eventsN Engl J Med2007357212109212217984165
   PubMed Web of Science ®Google Scholar
• TothPTorcetrapib and atherosclerosis: what happened and where do we go from here?Future Lipidol200723277284
   Web of Science ®Google Scholar
• NissenSETardifJCNichollsSJEffect of torcetrapib on the progression of coronary atherosclerosisN Engl J Med2007356131304131617387129
   PubMed Web of Science ®Google Scholar
• CannonCPDanskyHMDavidsonMDesign of the DEFINE trial: Determining the efficacy and tolerability of CETP INhibition with AnacEtrapibAm Heart J20091584513519e319781408
   PubMed Web of Science ®Google Scholar
• CannonCPShahSDanskyHMSafety of anacetrapib in patients with or at high risk for coronary heart diseaseN Eng J Med20103632524062415
   PubMed Web of Science ®Google Scholar
• KrishnaRBergmanAJJinBMultiple-dose pharmacodynamics and pharmacokinetics of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy subjectsClin Pharm Therap2008846679683
   PubMed Web of Science ®Google Scholar
• BloomfieldDCarlsonGLSapreAEfficacy and safety of the cholesteryl ester transfer protein inhibitor anacetrapib as monotherapy and coadministered with atorvastatin in dyslipidemic patientsAm Heart J20091572352360e219185645
   PubMed Web of Science ®Google Scholar
• KrishnaRAndersonMSBergmanAJEffect of the cholesteryl ester transfer protein inhibitor, anacetrapib, on lipoproteins in patients with dyslipidaemia and on 24-h ambulatory blood pressure in healthy individuals: two double-blind, randomised placebo-controlled phase I studiesLancet200737096031907191418068514
   PubMed Web of Science ®Google Scholar
• Yvan-CharvetLKlingJPaglerTCholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapibArterioscler Thromb Vasc Biol20103071430143820448206
   PubMed Web of Science ®Google Scholar
• NichollsSJGordonAJohanssonJEfficacy and safety of a novel oral inducer of apolipoprotein a-i synthesis in statin-treated patients with stable coronary artery disease: a randomized controlled trialJ Am Coll Cardiol20115791111111921255957
   PubMed Web of Science ®Google Scholar
• DavidsonMHApolipoprotein A-I therapy: promise, challenges, and disappointmentJ Am Coll Cardiol20115791120112121255956
   PubMed Web of Science ®Google Scholar
• BrownBGStukovskyKHZhaoXQSimultaneous low-density lipoprotein-C lowering and high-density lipoprotein-C elevation for optimum cardiovascular disease prevention with various drug classes, and their combinations: a meta-analysis of 23 randomized lipid trialsCurr Opin Lipidol200617663163617095907
   PubMed Web of Science ®Google Scholar
• TaylorAJVillinesTCStanekEJExtended-release niacin or ezetimibe and carotid intima-media thicknessN Engl J Med2009361222113212219915217
   PubMed Web of Science ®Google Scholar
• Niacin plus statin to prevent vascular events Available at: http://clinicaltrials.gov/ct/show/NCT00120289. Accessed March 24, 2011.
   Google Scholar
• Treatment of HDL to reduce the incidence of vascular events (HPS2-THRIVE) Available at: http://clinicaltrials.gov/ct/show/NCT00461630. Accessed March 24, 2011.
   Google Scholar
• IngelssonESchaeferEJContoisJHClinical utility of different lipid measures for prediction of coronary heart disease in men and womenJAMA2007298777678517699011
   PubMed Web of Science ®Google Scholar
• ParishSPetoRPalmerAThe joint effects of apolipoprotein B, apolipoprotein A 1, LDL cholesterol, and HDL cholesterol on risk: 3510 cases of acute myocardial infarction and 9805 controlsEur Heart J200930172137214619520708
   PubMed Web of Science ®Google Scholar
• LewingtonSWhitlockGClarkefor Prospective Studies CollaborationBlood cholesterol and vascular mortality by age, sex, and blood pressure: a meta-analysis of individual data from 61 prospective studies with 55000 vascular deathsLancet200737069021829183918061058
   PubMed Web of Science ®Google Scholar
• KasteleinJJPvan der SteegWAHolmeILipids, apolipoproteins, and their ratios in relation to cardiovascular events with statin treatmentCirculation2008117233002300918519851
   PubMed Web of Science ®Google Scholar
• CuiYBlumenthalRSFlawsJANon-high-density lipoprotein cholesterol level as a predictor of cardiovascular disease mortalityArch Intern Med2001161111413141911386890
   PubMedGoogle Scholar
• PischonTGirmanCJSacksFMRifaiNStampferMJRimmEBNon-high-density lipoprotein cholesterol and apolipoprotein B in the prediction of coronary heart disease in menCirculation2005112223375338316316964
   PubMed Web of Science ®Google Scholar
• El HarchaouiKvan der SteegWAStroesESValue of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population StudyJ Am Coll Cardiol200749554755317276177
   PubMed Web of Science ®Google Scholar
• MoraSOtvosJDRifaiNRosensonRSBuringJERidkerPMLipoprotein particle profiles by nuclear magnetic resonance compared with standard lipid and apolipoproteins in predicting incident cardiovascular disease in womenCirculation2009119793193919204302
   PubMed Web of Science ®Google Scholar
• KathiresanSOtvosJDSullivanLMIncreased small low-density lipoprotein particle number. A prominent feature of the metabolic syndrome in the Framingham Heart StudyCirculation20061131202916380547
   PubMed Web of Science ®Google Scholar
• OtvosJDCollinsDFreedmanSDLow-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention TrialCirculation2006113121556156316534013
   PubMed Web of Science ®Google Scholar
• HsiaJOtvosJDRossouwJEfor the Women’s Health Initiative Research GroupLipoprotein particle concentrations may explain the absence of coronary protection in the women’s health initiative hormone trialsArterioscler Thromb Vasc Biol20082891666167118599797
   PubMed Web of Science ®Google Scholar
• AdielsMBorénJCaslakeMJOverproduction of VLDL1 driven by hyperglycemia is a dominant feature of diabetic dyslipidemiaArterioscler Thromb Vasc Biol20052581697170315947244
   PubMed Web of Science ®Google Scholar
• BrunzellJDDavidsonMFurbergCDlipoprotein management in patients with cardiometabolic risk. consensus conference report from the American Diabetes Association and the American College of Cardiology FoundationJ Am Coll Cardiol200851151512152418402913
   PubMed Web of Science ®Google Scholar
• ContoisJHMcConnellJPSethiAAApolipoprotein B and cardiovascular disease risk: position statement from the AACC lipoproteins and vascular diseases division working group on best practicesClin Chem200955340741919168552
   PubMed Web of Science ®Google Scholar
• MoraSSzkloMOtvosJDLDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA)Atherosclerosis2007192121121716765964
   PubMed Web of Science ®Google Scholar
• ShimabukuroMHigaMTanakaHShimabukuroTYamakawaKMasuzakiHDistinct effects of pitavastatin and atorvastatin on lipoprotein subclasses in patients with Type 2 diabetes mellitusDiabet Med201111810.1111/j.1464-5491.2011.03240.x [Epub ahead of print].
   Web of Science ®Google Scholar
• RosensonRSOtvosJDHsiaJEffects of rosuvastatin and atorvastatin on low-density and high-density lipoprotein particle concentrations in patients with the metabolic syndrome: a randomized, double-blind, controlled studyDiabetes Care20093261087109119265025
   PubMed Web of Science ®Google Scholar
• DayspringTDallTAbuhajirMMoving beyond LDL-C: incorporating lipoprotein particle numbers and geometric parameters to improve clinical outcomesResearch Reports Clin Cardiol20101110
   Google Scholar
• LiuJSemposCTDonahueRPDornJTrevisanMGrundySMNon-high-density lipoprotein and very-low-density lipoprotein cholesterol and their risk predictive values in coronary heart diseaseAm J Cardiol200698101363136817134630
   PubMed Web of Science ®Google Scholar
• TakahashiOGlasziouPPPereraRLipid re-screening: what is the best measure and interval?Heart201096644845219528038
   PubMed Web of Science ®Google Scholar
• GlasziouPPIrwigLHeritierSMonitoring cholesterol levels: measurement error or true change?Ann Intern Med2008148965666118458278
   PubMed Web of Science ®Google Scholar
• McQueenMJHawkenSWangXLipids, lipoproteins, and apolipoproteins as risk markers of myocardial infarction in 52 countries (the INTERHEART study): a case-control studyLancet2008372963422423318640459
   PubMed Web of Science ®Google Scholar
• NordestgaardBGChapmanMJRayKfor the European Atherosclerosis Society Consensus PanelLipoprotein(a) as a cardiovascular risk factor: current statusEur Heart J201031232844285320965889
   PubMed Web of Science ®Google Scholar
• BarterPJBallantyneCMCarmenaRApo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: report of the thirty-person/ten country panelJ Intern Med2006259324725816476102
   PubMed Web of Science ®Google Scholar
• CromwellWCOtvosJDKeyesMJLDL particle number and risk of future cardiovascular disease in the Framingham offspring study – implications for LDL managementJ Clin Lipidol20071658359219657464
   PubMed Web of Science ®Google Scholar
• LibbyPInflammation in atherosclerosisNature2002420691786887412490960
   PubMed Web of Science ®Google Scholar
• BlakeGJRidkerPMInflammatory bio-markers and cardiovascular risk predictionJ Intern Med2002252428329412366601
   PubMed Web of Science ®Google Scholar
• EspositoKGiuglianoDDiet and inflammation: a link to metabolic and cardiovascular diseasesEur Heart J2006271152016219650
   PubMed Web of Science ®Google Scholar
• RossRThe pathogenesis of atherosclerosis-a perspective for the 1990sNature199336264238018098479518
   PubMed Web of Science ®Google Scholar
• LibbyPOkamotoYRochaVZFolcoEInflammation in atherosclerosis: transition from theory to practiceCirc J201074221322020065609
   PubMed Web of Science ®Google Scholar
• HanssonGKLibbyPSchönbeckUYanZQInnate and adaptive immunity in the pathogenesis of atherosclerosisCirc Res200291428129112193460
   PubMed Web of Science ®Google Scholar
• HanssonGKInflammation, atherosclerosis, and coronary artery diseaseN Engl J Med20053521616859515843671
   PubMed Web of Science ®Google Scholar
• LibbyPNahrendorfMPittetMJSwirskiFKDiversity of denizens of the atherosclerotic plaque: not all monocytes are created equalCirculation2008117253168317018574058
   PubMed Web of Science ®Google Scholar
• SelvinEPaynterNPErlingerTPThe effect of weight loss on c-reactive protein: a systematic reviewArch Intern Med20071671313917210875
   PubMedGoogle Scholar
• KoenigWSundMFrohlichMC-reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992Circulation199922372429892589
   PubMed Web of Science ®Google Scholar
• RidkerPMBuringJECookNRRifaiNC-Reactive protein, the metabolic syndrome, and risk of incident cardiovascular events. An 8-year follow-up of 14 719 initially healthy American womenCirculation2003107339139712551861
   PubMed Web of Science ®Google Scholar
• JialalIThe role of the laboratory in the diagnosis of the metabolic syndromeAm J Clin Pathol2009132216116219605808
   PubMed Web of Science ®Google Scholar
• PitsavosCPanagiotakosDBTzimaNDiet, exercise, and C-reactive protein levels in people with abdominal obesity: the ATTICA Epidemiological StudyAngiology200758222523317495273
   PubMed Web of Science ®Google Scholar
• EsmaillzadahAKimiagarMMehrabiYAzadbakhtLHuFBWillettWCFruit and vegetable intakes, C-reactive protein, and the metabolic syndromeAm J Clin Nutr20068461489249717158434
   PubMed Web of Science ®Google Scholar
• MicallefMAMunroIAGargMLAn inverse relationship between plasma n-3 fatty acids and C-reactive protein in healthy individualsEur J Clin Nutr20096391154115619352379
   PubMed Web of Science ®Google Scholar
• ImhofAFroehlichMBrennerHEffect of alcohol consumption on systemic markers of inflammationLancet2001357925876376711253971
   PubMed Web of Science ®Google Scholar
• AlbertMAGlynnRJRidkerPMAlcohol consumption and plasma concentration of C-reactive proteinCirculation2003107344344712551869
   PubMed Web of Science ®Google Scholar
• GreenfieldJRSamarasKJenkinsABObesity is an important determinant of baseline serum C-reactive protein concentration in monozygotic twins, independent of genetic influencesCirculation2004109243022302815184288
   PubMed Web of Science ®Google Scholar
• JiaoPXuHAdipose inflammation: cause or consequence of obesity-related insulin resistanceDiabetes Metab Syndr Obes20081253121437153
   PubMedGoogle Scholar
• SchusterDPObesity and the development of type 2 diabetes: the effects of fatty tissue inflammationDiabetes Metab Syndr Obes2010325326221437093
   PubMedGoogle Scholar
• WangANakayamaTInflammation, a link between obesity and cardiovascular diseaseMediators Inflamm2010535918
   Google Scholar
• Lin XuLJiangCQLamTHThe metabolic syndrome is associated with subclinical atherosclerosis independent of insulin resistance: the Guangzhou Biobank Cohort Study-CVDClin Endocrinol (Oxf)201073218118820039893
   PubMed Web of Science ®Google Scholar
• EspositoKPontilloADi PaloCEffect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trialJAMA2003289141799180412684358
   PubMed Web of Science ®Google Scholar
• GargRTripathyDDandonaPInsulin resistance as a proinflammatory state: mechanisms, mediators, and therapeutic interventionsCurr Drug Targets20034648749212866663
   PubMed Web of Science ®Google Scholar
• EspositoKMarfellaRCiotolaMEffect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular inflammation in the metabolic syndrome: a randomized trialJAMA2004292121440144615383514
   PubMed Web of Science ®Google Scholar
• BelalcazarLMReboussinDMHaffnerSMfor The Look AHEAD Research GroupA 1-year lifestyle intervention for weight loss in individuals with type 2 diabetes reduces high C-reactive protein levels and identifies metabolic predictors of changeDiabetes Care201033112297230320682679
   PubMed Web of Science ®Google Scholar
• WasselCLBarrett-ConnorELaughlinGAssociation of circulating C-reactive protein and interleukin-6 with longevity into the 80s and 90s: The Rancho Bernardo StudyJ Clin Endocrinol Metab201095104748475520660034
   PubMed Web of Science ®Google Scholar
• KravitzBACorradaMMKawasCHHigh levels of serum C-reactive protein are associated with greater risk of all-cause mortality, but not dementia, in the oldest-old: results from the 90+ StudyJ Am Ger Soc2009574641646
   Web of Science ®Google Scholar
• CurrieCJPooleCDConwayPEvaluation of the association between the first observation and the longitudinal change in C-reactive protein, and all-cause mortalityHeart200894445746217761503
   PubMed Web of Science ®Google Scholar
• MarsikCKazemi-ShiraziLSchickbauerTC-reactive protein and all-cause mortality in a large hospital-based cohortClin Chem200854234334918156283
   PubMed Web of Science ®Google Scholar
• KaptogeSDi AngelantonioELoweGThe Emerging Risk Factors Collaboration. C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysisLancet2010375970913214020031199
   PubMed Web of Science ®Google Scholar
• KangasniemiO-PBiancariFLuukkonenJPreoperative C-reactive protein is predictive of long-term outcome after coronary artery bypass surgeryEur J Cardiothorac Surg200629698398516682213
   PubMed Web of Science ®Google Scholar
• IshiiHToriyamaTAoyamaTPrognostic values of C-reactive protein levels on clinical outcome after implantation of sirolimuseluting stents in patients on hemodialysisCirc Cardiovasc Interv20092651351820031768
   PubMed Web of Science ®Google Scholar
• OtakeHShiteJShinkeTRelation between plasma adiponectin, high sensitivity C-reactive protein, and coronary plaque components in patients with acute coronary syndromeAm J Cardiol200810111718157956
   PubMed Web of Science ®Google Scholar
• MorrowDAde LemosJASabatineMSClinical relevance of C-reactive protein during follow-up of patients with acute coronary syndromes in the Aggrastat-to-Zocor TrialCirculation2006114428128816847150
   PubMed Web of Science ®Google Scholar
• NissenSEDoes intensive statin therapy lower mortality and cardiovascular event risk in patients with acute coronary syndrome?Nat Clin Pract Cardiovasc Med200521101116265333
   PubMedGoogle Scholar
• RadjeshJBisoendialRJBoekholdtSMVergeerMStroesESGKasteleinJJPC-reactive protein is a mediator of cardiovascular diseaseEur Heart J201031172087209120685682
   PubMed Web of Science ®Google Scholar
• WeberMBhattDLBrennanDMfor the CHARISMA InvestigatorsHigh-sensitivity C-reactive protein and clopidogrel treatment in patients at high risk of cardiovascular events: a substudy from the CHARISMA trialHeart201197862663121393433
   PubMed Web of Science ®Google Scholar
• HanssonGKLibbyPThe immune response in atherosclerosis: a double-edged swordNat Rev Immunol20066750851916778830
   PubMed Web of Science ®Google Scholar
• PackardRRLibbyPInflammation in atherosclerosis: from vascular biology to biomarker discovery and risk predictionClin Chem2008541243818160725
   PubMed Web of Science ®Google Scholar
• TakeuchiOAkiraSPattern recognition receptors and inflammationCell2010140680582020303872
   PubMed Web of Science ®Google Scholar
• ChangM-KBinderCHTorzewskiMWitztumJLC-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipidsProc Natl Acad Sci U S A20029920130431304812244213
   PubMed Web of Science ®Google Scholar
• BuDXLichtmanAHT cells and blood vessels. costimulation turns up the pressureCirculation2010122242495249821126974
   PubMed Web of Science ®Google Scholar
• LumengCNMaillardISaltielART-ing up inflammation in fatNat Med200915884684719661987
   PubMed Web of Science ®Google Scholar
• VinhAChenWBlinderYInhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertensionCirculation2010122242529253721126972
   PubMed Web of Science ®Google Scholar
• RizzoMCorradoECoppolaGThe predictive role of C-reactive protein in patients with hypertension and subclinical atherosclerosisIntern Med J200939853954519323703
   PubMed Web of Science ®Google Scholar
• NovoSRussoRToiaPSubclinical atherosclerosis, inflammation and eventsJournal ESC Council Clin Cardiol2011191613
   Google Scholar
• Van RoyenNPiekJJSchaperWFultonWFA critical review of clinical arteriogenesis researchJ Am Coll Cardiol2009551172520117358
   PubMed Web of Science ®Google Scholar
• De GrootDHoeferIEGrundmannSArteriogenesis requires toll-like receptor 2 and 4 expression in bone-marrow derived cellsJ Mol Cell Cardiol2011501253220708624
   PubMed Web of Science ®Google Scholar
• MonacoCInnate immunity meets arteriogenesis: The versatility of toll-like receptorsJ Mol Cell Cardiol201150191220971117
   PubMed Web of Science ®Google Scholar
• De LorgerilMSalenPMartinJLMonjaudIBoucherPMamelleNMediterranean dietary pattern in the randomized trial: prolonged survival and possible reduced cancer rateArch Int Med199815811118111879625397
   PubMedGoogle Scholar
• De LorgerilMSalenPMartinJLMonjaudIDelayeJMamelleNMediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction – final report of the Lyon Diet Heart StudyCirculation19999967797859989963
   PubMed Web of Science ®Google Scholar
• StamlerJStamlerRNeatonJDLow risk-factor profile and long-term cardiovascular and noncardiovascular mortality and life expectancy: findings for 5 large cohorts of young adult and middle-aged men and womenJAMA1999282212012201810591383
   PubMed Web of Science ®Google Scholar
• De LorgerilMSalenPDiet as preventive medicine in cardiologyCurr Opin Cardiol200015536437011128190
   PubMed Web of Science ®Google Scholar
• KnoopsKTde GrootLCKromhoutDMediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE projectJAMA2004292121433143915383513
   PubMed Web of Science ®Google Scholar
• TrichopoulouACostacouTBamiaCTrichopoulosDAdherence to a Mediterranean diet and survival in a Greek populationN Engl J Med2003348262599260812826634
   PubMed Web of Science ®Google Scholar
• MitrouPNKipnisVThiébautACMMediterranean dietary pattern and prediction of all-cause mortality in a US population: results from the NIH-AARP Diet and Health StudyArch Intern Med2007167222461246818071168
   PubMed Web of Science ®Google Scholar
• CroweFLRoddamAWKeyTJEuropean Prospective Investigation into Cancer and Nutrition (EPIC)-Heart Study CollaboratorsFruit and vegetable intake and mortality from ischaemic heart disease: results from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Heart studyEur Heart J201132101235124321245490
   PubMed Web of Science ®Google Scholar
• CapewellSLloyd-JonesDMOptimal cardiovascular prevention strategies for the 21st centuryJAMA2010304182057205821063015
   PubMed Web of Science ®Google Scholar
• WilsonJTLloyd-JonesDMBiomarkers for coronary heart disease clinical risk prediction: A critical appraisalPrev Cardiol201013416016520860638
   PubMedGoogle Scholar
• RobinsonJGWangSSmithBJJacobsonTAMeta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease riskJ Am Coll Cardiol200953431632219161879
   PubMed Web of Science ®Google Scholar
• BlahaMBlumenthalRBrintonEJacobsonTOn behalf of the National Lipid Association Taskforce on Non-HDL CholesterolThe importance of non-HDL cholesterol reporting in lipid managementJ Clin Lipidol20082426727321291742
   PubMed Web of Science ®Google Scholar
• RobinsonJGAre you targeting non-high-density lipoprotein cholesterol?J Am Coll Cardiol2010551424420117362
   PubMed Web of Science ®Google Scholar
• WilkinsJTLloyd-JonesDMShort-term versus lifetime risk assessment for cardiovascular disease: Pros, cons, and clinical implicationsCurr Cardiovasc Risk Rep200932144149
   Google Scholar
• PencinaMJD’AgostinoRBSrLarsonMGMassaroJMVasanRSPredicting the 30-year risk of cardiovascular disease: the Framingham Heart StudyCirculation2009119243078308419506114
   PubMed Web of Science ®Google Scholar
• RidkerPMDanielsonEFonsecaFAJUPITER Study GroupRosuvastatin to prevent vascular events in men and women with elevated C-reactive proteinN Engl J Med2008359212195220718997196
   PubMed Web of Science ®Google Scholar
• ManciaGLaurentSAgabiti-RoseiEReappraisal of European guidelines on hypertension management: a European Society of Hypertension Task Force documentJ Hypertension2009271121212158
   PubMed Web of Science ®Google Scholar
• KoenigWRidkerPMRosuvastatin for primary prevention in patients with European systematic coronary risk evaluation risk >5% or Framingham risk >20%: Post hoc analyses of the JUPITER trial requested by the European health authoritiesEur Heart J2011321758320971747
   PubMed Web of Science ®Google Scholar
• ChoudhryNKPatrickARGlynnRJAvornJThe cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levelsJ Am Coll Cardiol201157778479121310313
   PubMed Web of Science ®Google Scholar
• HlatkyMThe cost-effectiveness of rosuvastatin therapy: JUPITER (Justification for the Use of statins in Prevention: An Intervention Trial Evaluating Rosuvastatin)J Am Coll Cardiol201157779279321310314
   PubMed Web of Science ®Google Scholar
• De LorgerilMSalenPAbramsonJCholesterol lowering, cardiovascular diseases, and the rosuvastatin-JUPITER controversy: a critical reappraisalArch Intern Med2010170121032103620585068
   PubMedGoogle Scholar
• Carrera-BastosPFontesMO’KeefeJHLindebergSCordainLThe Western Diet and lifestyle and diseases of civilizationRes Reports Clin Cardiol201121535
   Google Scholar
• MookadamFMoustafaSELesterSJWarsameTSubclinical atherosclerosis: Evolving role of carotid intima-media thicknessPrev Cardiol201013418619720860643
   PubMedGoogle Scholar
• LiviakisLPogueBParamsothyPBourneAGillEACarotid intima-media thickness for the practicing lipidologistJ Clin Lipidol201041243521122625
   PubMed Web of Science ®Google Scholar
• GoldbergerZDValleJADandekarVKAre changes in carotid intima-media thickness related to risk of nonfatal myocardial infarction? A critical review and meta-regression analysisAmer Heart J2010160470171420934565
   PubMed Web of Science ®Google Scholar
• NambiVChamblessLFolsomARCarotid intima-media thickness and presence or absence of plaque improves prediction of coronary heart disease risk: the ARIC (Atherosclerosis Risk In Communities) studyJ Am Coll Cardiol201055151600160720378078
   PubMed Web of Science ®Google Scholar
• GerberTCTaylorAJCarotid intima-media thickness: can it close the “detection gap” for cardiovascular risk?Mayo Clin Proc200984321822019252107
   PubMed Web of Science ®Google Scholar
• LesterSJEleidMFKhandheriaBKHurstRTCarotid intima-media thickness and coronary artery calcium score as indications of subclinical atherosclerosisMayo Clin Proc200984322923319252109
   PubMed Web of Science ®Google Scholar
• SteinJHJohnsonHMCarotid intima-media thickness, plaques, and cardiovascular disease risk: implications for preventive cardiology guidelinesJ Am Coll Cardiol201055151608161020378079
   PubMed Web of Science ®Google Scholar
• SibalLAgarwalSCHomePDCarotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetesDiab Metab Syndr Obesity201142334
   PubMedGoogle Scholar
• SharmaKBlahaMJBlumenthalRSMusunuruKClinical and Research applications of carotid intima-media thicknessAm J Cardiol200910391316132019406278
   PubMed Web of Science ®Google Scholar
• CostanzoPPerrone-FilardiPVassalloEDoes carotid intima-media thickness regression predict reduction of cardiovascular events? A meta-analysis of 41 randomized trialsJ Am Coll Cardiol201056242006202021126642
   PubMed Web of Science ®Google Scholar
• SteinJHKorcarzCEHurstRTUse of carotid ultrasound to identify subclinical vascular disease and evaluate cardiovascular disease risk: a consensus statement from the American Society of Echocardiography Carotid Intima-Media Thickness Task ForceJ Am Soc Echocardiogr20082129311118261694
   PubMed Web of Science ®Google Scholar
• United States Preventive Services Task ForceUsing nontraditional risk factors in coronary heart disease risk assessment: US Preventive Services Task Force Recommendation StatementAnn Intern Med2009151747448219805770
   PubMed Web of Science ®Google Scholar
• PolonskyTSMcClellandRLJorgensenNWCoronary artery calcium score and risk classification for coronary heart disease predictionJAMA2010303161610161620424251
   PubMed Web of Science ®Google Scholar
• DetranoRGuerciADCarrJJCoronary calcium as a predictor of coronary events in four racial or ethnic groupsN Engl J Med2008358131336134518367736
   PubMed Web of Science ®Google Scholar
• ShahPKThe SHAPE Paradigm: a commentaryCirc Cardiovasc Qual Outcomes20103110610920123677
   PubMed Web of Science ®Google Scholar
• PatelABudoffMScreening for heart disease: C-reactive protein versus coronary artery calciumExpert Rev Cardiovasc Ther20108112513120014938
   PubMedGoogle Scholar
• ErbelRMöhlenkampSMoebusSfor the Heinz Nixdorf Recall Study Investigative GroupCoronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis: The Heinz Nixdorf Recall StudyJ Am Coll Cardiol201056171397140620946997
   PubMed Web of Science ®Google Scholar
• Elias-SmaleSEProençaRVKollerMTCoronary calcium score improves classification of coronary heart disease risk in the elderly: The Rotterdam StudyJ Am Coll Cardiol201056171407141420946998
   PubMed Web of Science ®Google Scholar
• DuprezDCoronary artery calcification, an improvement in risk classification: need for reappraisal?J Am Coll Cardiol201056171415141720946999
   PubMed Web of Science ®Google Scholar
• RumbergerJAUsing noncontrast cardiac CT and coronary artery calcification measurements for cardiovascular risk assessment and management in asymptomatic adultsVasc Health Risk Manag2010657959120730074
   PubMedGoogle Scholar
• PiersLHSalachovaFSlartRHJAThe role of coronary artery calcification score in clinical practiceBMC Cardiovascular Disorders200883819091061
   PubMed Web of Science ®Google Scholar
• RaggiPGongoraMCGopalACallisterTQBudoffMShawLJCoronary artery calcium to predict all-cause mortality in elderly men and womenJ Am Coll Cardiol2008521172318582630
   PubMed Web of Science ®Google Scholar
• SharmaRKSharmaRKVoelkerDJCardiac risk stratification: role of the coronary calcium scoreVasc Health Risk Manag2010660361120730016
   PubMedGoogle Scholar
• NaghaviMFalkEHechtHSShahPKFor the SHAPE Task ForceThe First SHAPE (Screening for Heart Attack Prevention and Education) GuidelineCrit Pathw Cardiol20065418719018340236
   PubMedGoogle Scholar
• NaghaviMScreening for early detection and prevention of heart attackPresented at the American College of Cardiology 59th Annual Scientific SessionMarch, 2010 Available at: www.shapesociety.org/images/downloadshapepresentation.jpg. Accessed March 24, 2011.
   Google Scholar
• NaghaviMAsymptomatic Atherosclerosis: Pathophysiology, Detection and TreatmentNew YorkHumana Press/Springer-Verlag2011 ISBN 978-1-60327-178-3
   Google Scholar
• NasirKMichosEDBlumenthalRSRaggiPDetection of high-risk young adults and women by coronary calcium and National Cholesterol Education Program Panel III GuidelinesJ Am Coll Cardiol200546101931193616286182
   PubMed Web of Science ®Google Scholar
• ShawLJRaggiPBermanDSCallisterTQCoronary artery calcium as a measure of biologic ageAtherosclerosis2006188111211916289071
   PubMed Web of Science ®Google Scholar
• HarveySHechtHSA zero coronary artery calcium score: pricelessJ Am Coll Cardiol201055111118112020223366
   PubMed Web of Science ®Google Scholar
• KabulPDouglasPSAtherosclerosis imaging: prognostically useful or merely more of what we know?Circ Cardiovasc Imaging20092215016019808581
   PubMed Web of Science ®Google Scholar
• Richard ContiCIs calcium scoring of the coronary arteries necessary for proper management of asymptomatic subjects with classic risk factors?Clin Cardiol2010331165865921089109
   PubMed Web of Science ®Google Scholar
• BudoffMJGuptaMRadiation exposure from cardiac imaging procedures: do the risks outweight the benefits?J Am Coll Cardiol56971271420619568
   PubMed Web of Science ®Google Scholar
• ChenJEinsteinAJFazelRcumulative exposure to ionizing radiation from diagnostic and therapeutic cardiac imaging procedures: a population-based analysisJ Am Coll Cardiol201056970271120619569
   PubMed Web of Science ®Google Scholar
• GibbonsRJGerberTCCalcium scoreing with computed tomography: what is the radiation risk?Arch Int Med2009169131185118719597066
   PubMedGoogle Scholar
• McculloughPAChinnaiyanKMAnnual progression of coronary calcification in trials of preventive therapies: a systematic reviewArch Int Med2009169222064207020008688
   PubMedGoogle Scholar
• O’MalleyPGA double take on serial measurement of coronary artery calcificationArch Int Med2009169222051205220008686
   PubMedGoogle Scholar
• SeeRLindseyJBPatelMJApplication of the screening for Heart Attack Prevention and Education Task Force Recommendations to an urban population: observations from the Dallas Heart StudyArch Intern Med2008168101055106218504333
   PubMedGoogle Scholar
• PletcherMJGreenlandPCoronary calcium scoring and cardiovascular risk: the SHAPE of things to comeArch Intern Med2008168101027102818504328
   PubMedGoogle Scholar
• IoannidisJPATzoulakiIWhat makes a good predictor? the evidence applied to coronary artery calcium scoreJAMA2010303161646164720424257
   PubMed Web of Science ®Google Scholar
• EinsteinAWeinerSBernheimAMultiple testing, cumulative radiation dose, and clinical indications in patients undergoing myocardial perfusion imagingJAMA2010304192137214421078807
   PubMed Web of Science ®Google Scholar
• EisenbergMJAfilaloJALawlerPRAbrahamowiczMRichardHPiloteLCancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarctionCMAJ2011182443043621324846
   PubMed Web of Science ®Google Scholar
• DorfmanALFazelREinsteinAJUse of medical imaging procedures with ionizing radiation in children: a population-based studyArch Pediatr Adolesc Med2011165545846421199972
   PubMedGoogle Scholar
• FazelRKrumholzHMWangYExposure to low-dose ionizing radiation from medical imaging proceduresN Engl J Med2009361984985719710483
   PubMed Web of Science ®Google Scholar
• SodicksonABaeyensPFAndrioleKPRecurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adultsRadiology2009251117518419332852
   PubMed Web of Science ®Google Scholar
• MarkDBBermanDSBudoffMJACCF/ACR/AHA/NASCI/SAIP/SCAI/SCCT 2010Expert consensus document of coronary computed tomographic angiography: a report of the American College of Cardiology Foundation task force on expert consensus documentsJ Am Coll Cardiol201055232663269920513611
   PubMed Web of Science ®Google Scholar
• SarwarAShawLJShapiroMDdiagnostic and prognostic value of absence of coronary artery calcificationJACC Cardiovasc Imaging20092667568819520336
   PubMed Web of Science ®Google Scholar
• GarciaMJFusterVAn ounce of prevention with a calcium score scan?JACC Cardiovasc Imaging20092668969119520337
   PubMed Web of Science ®Google Scholar
• CademartiriFMaffeiEPalumboACoronary calcium score and computed tomography coronary angiography in high-risk asymptomatic subjects: assessment of diagnostic accuracy and prevalence of non-obstructive coronary artery diseaseEur Radiol201020484685419760230
   PubMed Web of Science ®Google Scholar
• GottliebIMillerJMArbab-ZadehAThe absence of coronary calcification does not exclude obstructive coronary artery disease or the need for revascularization in patients referred for conventional coronary angiographyJ Am Coll Cardiol201055762763420170786
   PubMed Web of Science ®Google Scholar
• RedbergRFWhat is the prognostic value of a zero calcium score?J Am Coll Cardiol201055763563620170787
   PubMed Web of Science ®Google Scholar
• BaumannBMChenEHMillsAMPatient perceptions of computed tomographic imaging and their understanding of radiation risk and exposureAnn Emerg Med20101210 [Epub ahead of print].
   Web of Science ®Google Scholar
• Berrington de GonzalezAMaheshMKimKPProjected cancer risks from computed tomographic scans performed in the United States in 2007Arch Intern Med2009169222071207720008689
   PubMed Web of Science ®Google Scholar
• Fernandez-FrieraLGarcia-AlvarezABagheriannejad-EsfahaniFdiagnostic value of coronary artery calcium scoring in low-intermediate risk patients evaluated in the emergency department for acute coronary syndromeAm J Cardiol20111071172321146680
   PubMed Web of Science ®Google Scholar
• NabiFChangSMPrattCMCoronary artery calcium scoring in the emergency department: identifying which patients with chest pain can be safely discharged homeAnn Emerg Med201056322022920138399
   PubMed Web of Science ®Google Scholar
• BudoffMJCoronary calcium remains an effective filter for invasive angiographyJ Am Coll Cardiol201056761361420688222
   PubMed Web of Science ®Google Scholar
• OrringerCEThe absence of coronary calcium: clinical and therapeutic implications for the clinical lipidologistJ Clin Lipidol20104647247721122693
   PubMed Web of Science ®Google Scholar
• RedbergRFReplyJ Am Coll Cardiol2010567615615
   Web of Science ®Google Scholar
• McEvoyJWBlahaMJDeFilippisAPCoronary artery calcium progression: an important clinical measurement? A review of published reportsJ Am Coll Cardiol201056201613162221050970
   PubMed Web of Science ®Google Scholar
• Heart Protection Study Collaborative GroupStatin cost-effectiveness in the United States for people at different vascular risk levelsCirc Cardiovasc Qual Outcomes200922657220031817
   PubMed Web of Science ®Google Scholar
• HaywardRAKrumholzHMZulmanDMTimbieJWVijanSOptimizing statin treatment for primary prevention of coronary artery diseaseAnn Intern Med20101522697720083825
   PubMed Web of Science ®Google Scholar
• RidkerPMRifaiNClearfieldMMeasurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary eventsN Engl J Med2001344261959196511430324
   PubMed Web of Science ®Google Scholar
• MahoneyEMTargeting patients for statin therapy for the primary prevention of vascular events: what is the best approach?Circulation2010122151446144820876432
   PubMed Web of Science ®Google Scholar
• HaywardRAHoferTPVijanSNarrative review: lack of evidence for recommended low-density lipoprotein treatment targets: a solvable problemAnn Intern Med2006145752053017015870
   PubMed Web of Science ®Google Scholar
• LiMOngKLTseHFCheungBMUtilization of lipid lowering medications among adults in the United States 1999–2006Atherosclerosis2010208245646019700160
   PubMed Web of Science ®Google Scholar
• LewisLSStrategies for statins: The CASE for fire and forgetBMJ2008336764140618292146
   PubMed Web of Science ®Google Scholar
• LewisLSThe most cost-effective statin strategy?BMJ2010341c3531 Available at: http://www.bmj.com/content/341/bmj.c3531/reply.20667950
   PubMed Web of Science ®Google Scholar
• SharmaMAnsariMTAbou-SettaAMSystematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemiaAnn Int Med2009151962263019884623
   PubMed Web of Science ®Google Scholar
• KrumholzHMHaywardRAShifting views on lipid lowering therapyBMJ2010341c353120667950
   PubMed Web of Science ®Google Scholar
• KnottLPatient UK. Primary prevention of cardiovascular disease Updated June 28, 2010. Available at: http://www.patient.co.uk/doctor/Primary-Prevention-of-Cardiovascular-Disease-(CVD).htm. Accessed March 24, 2011.
   Google Scholar
• O’KeefeJHJrCordainLHarrisWHMoeRMVogelROptimal low-density lipoprotein is 50 to 70 mg/dl: lower is better and physiologically normalJ Am Coll Cardiol200443112142214615172426
   PubMed Web of Science ®Google Scholar
• HochholzerWGiuglianoRPLipid lowering goals: back to nature?Ther Adv Cardiovasc Dis20104318519120400493
   PubMedGoogle Scholar
• O’KeefeHJrCordainLCardiovascular disease resulting from a diet and life-style at odds with our Paleolithic genome: how to become a 21st-century hunter-gathererMayo Clin Proc200479110110814708953
   PubMed Web of Science ®Google Scholar
• ChenZPetoRCollinsRMacMahonSLuJLiWSerum cholesterol concentration and coronary heart disease in population with low cholesterol concentrationsBMJ199130367972762821888927
   PubMed Web of Science ®Google Scholar
• DietschyJMTurleySDthematic review series: brain lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animalJ Lipid Res20044581375139715254070
   PubMed Web of Science ®Google Scholar
• DrexelHAczelSMarteTVonbankASaelyCHFactors predicting cardiovascular events in statin-treated diabetic and non-diabetic patients with coronary atherosclerosisAtherosclerosis2010208248448919748621
   PubMed Web of Science ®Google Scholar
• WaldNJLawMRA strategy to reduce cardiovascular disease by more than 80%BMJ20033267404141912829553
   PubMed Web of Science ®Google Scholar
• YusufSPaisPAfzalRthe Indian Polycap Study (TIPS)Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trialLancet200937396721341135119339045
   PubMed Web of Science ®Google Scholar
• CannonCPCan the polypill save the world from heart disease?Lancet200937396721313131419339044
   PubMed Web of Science ®Google Scholar
• SolimanEZMendisSDissanayakeWPA Polypill for primary prevention of cardiovascular disease: A feasibility study of the World Health OrganizationTrials201112321205325
   PubMed Web of Science ®Google Scholar
• FusterVSanzGA polypill for secondary prevention: time to move from intellectual debate to actionNat Clin Pract Cardiovasc Med20074417317380163
   PubMedGoogle Scholar
• FusterVPrime time for a polypill after myocardial infarction?Nat Clin Pract Cardiovasc Med2009628319174823
   PubMedGoogle Scholar
• WaldNJWaldDSThe polypill conceptHeart20109611420019207
   PubMedGoogle Scholar
• MaciosekMVCoffieldABFlottemeschTJEdwardsNMSolbergLIGreater Use Of Preventive Services In US Health Care Could Save Lives At Little Or No CostHealth Affairs20102991656166020820022
   PubMed Web of Science ®Google Scholar
• WebsterRHeeleyEPerceptions of risk: understanding cardiovascular diseaseRisk Manag Healthc Policy201034960
   PubMedGoogle Scholar
• MoscaLMochari-GreenbergerHDolorRJNewbyLKRobbKJTwelve-year follow-up of American women’s awareness of cardiovascular disease risk and barriers to heart healthCirc Cardiovasc Qual Outcomes20103212012720147489
   PubMed Web of Science ®Google Scholar
• PancioliAMBroderickJKothariRPublic perception of stroke warning signs and knowledge of potential risk factorsJAMA199827916128812929565010
   PubMed Web of Science ®Google Scholar
• RitchieJEHerscovitchFNorforJBBeliefs of blue collar workers regarding coronary risk behavioursHealth Educ Res19949195103
   Web of Science ®Google Scholar
• NorcrossJCKrebsPMProchaskaJOStages of changeJ Clin Psychol201167214315421157930
   PubMed Web of Science ®Google Scholar
• JanzNKBeckerMHThe Health Belief Model: a decade laterHealth Educ Q19841111476392204
   PubMedGoogle Scholar
• WeinsteinNDUnrealistic optimism about susceptibility to health problems: conclusions from a community-wide sampleJ Behav Med19871054815003430590
   PubMed Web of Science ®Google Scholar
• MoscaLBenjaminEJBerraKEffectiveness-based guidelines for the prevention of cardiovascular disease in women – 2011 update. A guideline from the American Heart AssociationCirculation2011123111243126221325087
   PubMed Web of Science ®Google Scholar
• RobinsSJLyassAZachariahJPMassaroJMVasanRSInsulin resistance and the relationship of a dyslipidemia to coronary heart disease: the Framingham Heart StudyArterioscler Thromb Vasc Biol20113151208121421311041
   PubMed Web of Science ®Google Scholar
• MöhlenkampSLehmannNMoebusSfor the Heinz Nixdorf Recall Study InvestigatorsQuantification of coronary atherosclerosis and inflammation to predict coronary events and all-cause mortalityJ Am Coll Cardiol201157131455146421435514
   PubMed Web of Science ®Google Scholar
• HammCWNefHMRolfAMöllmannHCalcium and C-reactive protein: hot enough to predict the future?J Am Coll Cardiol201157131465146721435515
   PubMed Web of Science ®Google Scholar
• ChironiGSimonAMegnienJ-LCoronary calcium data have limited impact on CHD risk-classificationInt J Cardiol2010 advance publication.10.1016/j.ijcard.2010.05.024 In press.
   Web of Science ®Google Scholar
• RubinJChangH-JNasirKAssociation between high-sensitivity C-reactive protein and coronary plaque subtypes assessed by 64-slice coronary computed tomography angiography in an asymptomatic populationCirc Cardiovasc Imaging2011420120921422167
   PubMed Web of Science ®Google Scholar
• RidkerPMHigh-sensitivity C-reactive protein, vascular imaging, and vulnerable plaque. More evidence to support trials of antiinflammatory therapy for cardiovascular risk reductionCirc Cardiovasc Imaging2011419519721586741
   PubMed Web of Science ®Google Scholar
• deGomaEMRaderDJNovel HDL-directed pharmacotherapeutic strategiesNat Rev Cardiol2011826627721243009
   PubMed Web of Science ®Google Scholar
• BruckertELabreucheJAmarencoPMeta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosisAtherosclerosis2010210235336120079494
   PubMed Web of Science ®Google Scholar