Efficacy and Safety of Ciprofol for Sedation/Anesthesia in Patients Undergoing Hysteroscopy: A Randomized, Parallel-Group, Controlled Trial

References

• Sutton C. Hysteroscopic surgery. Best practice & research. Clin Obstetr Gynaecol. 2006;20(1):105–137.
   Google Scholar
• Cicinelli E. Hysteroscopy without anesthesia: review of recent literature. J Minim Invasive Gynecol. 2010;17(6):703–708. doi:10.1016/j.jmig.2010.07.003
   PubMed Web of Science ®Google Scholar
• Carta G, Palermo P, Marinangeli F, et al. Waiting time and pain during office hysteroscopy. J Minim Invasive Gynecol. 2012;19(3):360–364. doi:10.1016/j.jmig.2012.01.017
   PubMed Web of Science ®Google Scholar
• Amer-Cuenca JJ, Marín-Buck A, Vitale SG, et al. Non-pharmacological pain control in outpatient hysteroscopies.. Minim Invasive Ther Allied Technol. 2020;29(1):10–19. doi:10.1080/13645706.2019.1576054
   PubMed Web of Science ®Google Scholar
• Gupta JK, Clark TJ, More S, et al. Patient anxiety and experiences associated with an outpatient “one-stop” “see and treat” hysteroscopy clinic. Surg Endosc. 2004;18(7):1099–1104. doi:10.1007/s00464-003-9144-3
   PubMed Web of Science ®Google Scholar
• Vitale SG, Caruso S, Ciebiera M, et al. Management of anxiety and pain perception in women undergoing office hysteroscopy: a systematic review. Arch Gynecol Obstet. 2020;301(4):885–894. doi:10.1007/s00404-020-05460-2
   PubMed Web of Science ®Google Scholar
• Hassan L, Gannon MJ. Anaesthesia and analgesia for ambulatory hysteroscopic surgery. Best practice & research. Clin Obstetr Gynaecol. 2005;19(5):681–691.
   Web of Science ®Google Scholar
• Yu J, Xiang B, Song Y, et al. ED50 of propofol in combination with low-dose sufentanil for intravenous anaesthesia in hysteroscopy. Basic Clin Pharmacol Toxicol. 2019;125(5):460–465. doi:10.1111/bcpt.13280
   PubMed Web of Science ®Google Scholar
• Avramov MN, White PF. Use of alfentanil and propofol for outpatient monitored anesthesia care: determining the optimal dosing regimen. Anesth Analg. 1997;85(3):566–572. doi:10.1213/00000539-199709000-00015
   PubMed Web of Science ®Google Scholar
• Bingol Tanriverdi T, Koceroglu I, Devrim S, et al. Comparison of sedation with dexmedetomidine vs propofol during hysteroscopic surgery: single-centre randomized controlled trial. J Clin Pharm Ther. 2019;44(2):312–317. doi:10.1111/jcpt.12793
   PubMed Web of Science ®Google Scholar
• Marik PE. Propofol: therapeutic indications and side-effects. Curr Pharm Des. 2004;10(29):3639–3649. doi:10.2174/1381612043382846
   PubMed Web of Science ®Google Scholar
• Qin L, Ren L, Wan S, et al. Design, synthesis, and evaluation of novel 2,6-disubstituted phenol derivatives as general anesthetics. J Med Chem. 2017;60(9):3606–3617. doi:10.1021/acs.jmedchem.7b00254
   PubMed Web of Science ®Google Scholar
• Teng Y, Ou MC, Wang X, et al. Pharmacokinetic and pharmacodynamic properties of ciprofol emulsion in Chinese subjects: a single center, open-label, single-arm dose-escalation Phase 1 study. Am J Transl Res. 2021;13(12):13791–13802.
   PubMed Web of Science ®Google Scholar
• Teng Y, Ou M, Wang X, et al. Efficacy and safety of ciprofol for the sedation/anesthesia in patients undergoing colonoscopy: phase IIa and IIb multi-center clinical trials. Eur J Pharma Sci. 2021;164:105904. doi:10.1016/j.ejps.2021.105904
   PubMed Web of Science ®Google Scholar
• Liu Y, Chen C, Liu N, et al. Efficacy and safety of ciprofol sedation in ICU patients with mechanical ventilation: a clinical trial study protocol. Adv Ther. 2021;38(10):5412–5423. doi:10.1007/s12325-021-01877-6
   PubMed Web of Science ®Google Scholar
• Doyle DJ, Goyal A, Garmon EH. American society of anesthesiologists classification. In: StatPearls. Treasure Island (FL): StatPearls PublishingCopyright © 2022, StatPearls Publishing LLC; 2022.
   Google Scholar
• Aldrete JA, Kroulik D. A postanesthetic recovery score. Anesth Analg. 1970;49(6):924–934. doi:10.1213/00000539-197011000-00020
   PubMed Web of Science ®Google Scholar
• Zhang S, Wang J, Ran R, et al. Efficacy and safety of remimazolam tosylate in hysteroscopy: a randomized, single-blind, parallel controlled trial. J Clin Pharm Ther. 2022;47(1):55–60. doi:10.1111/jcpt.13525
   PubMed Web of Science ®Google Scholar
• Hu C, Ou X, Teng Y, et al. Sedation effects produced by a ciprofol initial infusion or bolus dose followed by continuous maintenance infusion in healthy subjects: a Phase 1 trial. Adv Ther. 2021;38(11):5484–5500. doi:10.1007/s12325-021-01914-4
   PubMed Web of Science ®Google Scholar
• Wang X, Wang X, Liu J, et al. Effects of ciprofol for the induction of general anesthesia in patients scheduled for elective surgery compared to propofol: a Phase 3, multicenter, randomized, double-blind, comparative study. Eur Rev Med Pharmacol Sci. 2022;26(5):1607–1617. doi:10.26355/eurrev_202203_28228
   PubMed Web of Science ®Google Scholar
• Wu B, Zhu W, Wang Q, et al. Efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil during fiberoptic bronchoscopy: a prospective, randomized, double-blind, non-inferiority trial. Front Pharmacol. 2022;13:1091579. doi:10.3389/fphar.2022.1091579
   PubMed Web of Science ®Google Scholar
• Zeng Y, Wang DX, Lin ZM, et al. Efficacy and safety of HSK3486 for the induction and maintenance of general anesthesia in elective surgical patients: a multicenter, randomized, open-label, propofol-controlled Phase 2 clinical trial. Eur Rev Med Pharmacol Sci. 2022;26(4):1114–1124. doi:10.26355/eurrev_202202_28101
   PubMed Web of Science ®Google Scholar
• Liu Y, Yu X, Zhu D, et al. Safety and efficacy of ciprofol vs propofol for sedation in intensive care unit patients with mechanical ventilation: a multi-center, open label, randomized, phase 2 trial. Chin Med J. 2021;135(9):1043–1051.
   Web of Science ®Google Scholar
• Tan CH, Onsiong MK. Pain on injection of propofol. Anaesthesia. 1998;53(5):468–476. doi:10.1046/j.1365-2044.1998.00405.x
   PubMed Web of Science ®Google Scholar
• Doenicke AW, Roizen MF, Rau J, et al. Reducing pain during propofol injection: the role of the solvent. Anesth Analg. 1996;82(3):472–474. doi:10.1097/00000539-199603000-00007
   PubMed Web of Science ®Google Scholar
• Klement W, Arndt JO. Pain on injection of propofol: effects of concentration and diluent. Br J Anaesth. 1991;67(3):281–284. doi:10.1093/bja/67.3.281
   PubMed Web of Science ®Google Scholar
• Zhang X, Li S, Liu J. Efficacy and safety of remimazolam besylate versus propofol during hysteroscopy: single-centre randomized controlled trial. BMC Anesthesiol. 2021;21(1):156. doi:10.1186/s12871-021-01373-y
   PubMed Web of Science ®Google Scholar