21
Views
0
CrossRef citations to date
0
Altmetric
CLINICAL TRIAL REPORT

Determination of ED90s of Phenylephrine and Norepinephrine Infusion for Prevention of Spinal Anesthesia-Induced Hypotension in Patients with Preeclampsia During Cesarean Delivery

, ORCID Icon, , , , & ORCID Icon show all
Pages 2813-2821 | Received 03 Mar 2024, Accepted 01 Jul 2024, Published online: 05 Jul 2024

References

  • Mohta M, Garg A, Chilkoti GT, Malhotra, R K, et al. A randomised controlled trial of phenylephrine and noradrenaline boluses for treatment of postspinal hypotension during elective caesarean section. Anaesthesia. 2019;74(7):850–855. doi:10.1111/anae.14675
  • Massoth C, Töpel L, Wenk M. Hypotension after spinal anesthesia for cesarean section: how to approach the iatrogenic sympathectomy. Curr Opin Anaesthesiol. 2020;33(3):291–298. doi:10.1097/ACO.0000000000000848
  • Chungsamarnyart Y, Wacharasint P, Carvalho B. Hemodynamic profiles with and without left uterine displacement: a randomized study in term pregnancies receiving subarachnoid blockade for cesarean delivery. J Clin Anesth. 2020;64:109796. doi:10.1016/j.jclinane.2020.109796
  • Michelsen TM, Tronstad C, Rosseland LA. Blood pressure and cardiac output during caesarean delivery under spinal anaesthesia: a prospective cohort study. BMJ Open. 2021;11(6):e046102. doi:10.1136/bmjopen-2020-046102
  • Nikooseresht M, Seif Rabiei MA, Hajian P, et al. Comparing the hemodynamic effects of spinal anesthesia in preeclamptic and healthy parturients during cesarean section. Anesth Pain Med. 2016;6(3):e11519. doi:10.5812/aapm.11519
  • Russell R. Preeclampsia and the anaesthesiologist: current management. Curr Opin Anaesthesiol. 2020;33(3):305–310. doi:10.1097/ACO.0000000000000835
  • Mohta M, Duggal S, Chilkoti GT. Randomised double-blind comparison of bolus phenylephrine or ephedrine for treatment of hypotension in women with pre-eclampsia undergoing caesarean section. Anaesthesia. 2018;73(7):839–846. doi:10.1111/anae.14268
  • Guo L, Qin R, Ren X, et al. Prophylactic norepinephrine or phenylephrine infusion for bradycardia and post-spinal anaesthesia hypotension in patients with preeclampsia during Caesarean delivery: a randomised controlled trial. Br J Anaesth. 2022;128(5):e305–e307. doi:10.1016/j.bja.2022.01.027
  • Heesen M, Girard T, Klimek M. Noradrenaline - at best it is not worse. A comparison with phenylephrine in women undergoing spinal anaesthesia for caesarean section. Anaesthesia. 2021;76(6):743–747. doi:10.1111/anae.15363
  • American College of Obstetricians and Gynecologists; task force on hypertension in pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on hypertension in pregnancy. Obstet Gynecol. 2013;122:1122–1131.
  • Committee on Practice Bulletins–Obstetrics. Gestational hypertension and preeclampsia: ACOG Practice Bulletin Summary, Number 222. Obstet Gynecol. 2020;135:1492–1495. doi:10.1097/AOG.0000000000003892
  • Qian J, Zhao YP, Deng JL, et al. Determination of the relative potency of phenylephrine and norepinephrine given as infusions for preventing hypotension during combined spinal-epidural anesthesia for cesarean delivery: a randomized up-and-down sequential allocation study. Front Pharmacol. 2022;13:942005. doi:10.3389/fphar.2022.942005
  • Qian J, Liu L, Zheng X, Xiao F. Does an earlier or late intravenous injection of ondansetron affect the dose of phenylephrine needed to prevent spinal-anesthesia induced hypotension in cesarean sections? Drug Des Devel Ther. 2020;14:2789–2795. doi:10.2147/DDDT.S257880
  • Lim G, Facco FL, Nathan N, et al. A Review of the impact of obstetric anesthesia on maternal and neonatal outcomes. Anesthesiology. 2018;129(1):192–215. doi:10.1097/ALN.0000000000002182
  • Wang X, Mao M, Liu S, et al A comparative study of bolus norepinephrine, phenylephrine, and ephedrine for the treatment of maternal hypotension in parturients with preeclampsia during cesarean delivery under spinal anesthesia. Med Sci Monit. 2019;25:1093–1101. doi:10.12659/MSM.914143
  • Henke VG, Bateman BT, Leffert LR. Focused review: spinal anesthesia in severe preeclampsia. Anesth Analg. 2013;117(3):686–693. doi:10.1213/ANE.0b013e31829eeef5
  • Ferré F, Martin C, Bosch L, et al Control of spinal anesthesia-induced hypotension in adults. Local Reg Anesth. 2020;13:39–46. doi:10.2147/LRA.S240753
  • Jin WD, Mao JQ, Liu J, et al. Comparative dose-response study on the infusion of norepinephrine combined with crystalloid coload versus colloid coload for preventing hypotension during spinal anesthesia for cesarean delivery. Drug Des Devel Ther. 2022;16:2617–2626. doi:10.2147/DDDT.S378453
  • Guo L, Xiong X, Qin R, et al. Prophylactic norepinephrine combined with 6% hydroxyethyl starch (130/0.4) co-load infusion for preventing postspinal anesthesia hypotension during cesarean section: a randomized, controlled, dose-finding trial. Daru. 2023. doi:10.1007/s40199-023-00479-7
  • Xiao F, Shen B, Xu WP, et al Dose-response study of 4 weight-based phenylephrine infusion regimens for preventing hypotension during cesarean delivery under combined spinal-epidural anesthesia. Anesth Analg. 2020;130(1):187–193. doi:10.1213/ANE.0000000000004092
  • Allen TK, George RB, White WD, et al. A double-blind, placebo-controlled trial of four fixed rate infusion regimens of phenylephrine for hemodynamic support during spinal anesthesia for cesarean delivery. Anesth Analg. 2010;111(5):1221–1229. doi:10.1213/ANE.0b013e3181e1db21
  • Nugroho AM, Sugiarto A, Chandra S, et al. A comparative study of fractionated versus single dose injection for spinal anesthesia during cesarean section in patients with pregnancy-induced hypertension. Anesth Pain Med. 2019;9(1):e85115. doi:10.5812/aapm-85115
  • Ngan Kee WD, Lee SW, Ng FF, et al. Randomized double-blinded comparison of norepinephrine and phenylephrine for maintenance of blood pressure during spinal anesthesia for cesarean delivery. Anesthesiology. 2015;122(4):736–745. doi:10.1097/ALN.0000000000000601
  • Ngan Kee WD. A random-allocation graded dose-response study of norepinephrine and phenylephrine for treating hypotension during spinal anesthesia for cesarean delivery. Anesthesiology. 2017;127(6):934–941. doi:10.1097/ALN.0000000000001880
  • Mohta M, Dubey M, Malhotra RK, et al. Comparison of the potency of phenylephrine and norepinephrine bolus doses used to treat post-spinal hypotension during elective caesarean section. Int J Obstet Anesth. 2019;38:25–31. doi:10.1016/j.ijoa.2018.12.002
  • Nikooseresht M, Seifrabiei MA, Hajian P, et al. A clinical trial on the effects of different regimens of phenylephrine on maternal hemodynamic after spinal anesthesia for cesarean section. Anesth Pain Med. 2020;10(4):e58048. doi:10.5812/aapm.58048
  • Heesen M, Hilber N, Rijs K, et al. A systematic review of phenylephrine vs. noradrenaline for the management of hypotension associated with neuraxial anaesthesia in women undergoing caesarean section. Anaesthesia. 2020;75(6):800–808. doi:10.1111/anae.14976
  • Theodoraki K, Hadzilia S, Valsamidis D, et al. Prevention of hypotension during elective cesarean section with a fixed-rate norepinephrine infusion versus a fixed-rate phenylephrine infusion. alpha double-blinded randomized controlled trial. Int J Surg. 2020;84:41–49. doi:10.1016/j.ijsu.2020.10.006
  • Sharkey AM, Siddiqui N, Downey K, et al. Comparison of intermittent intravenous boluses of phenylephrine and norepinephrine to prevent and treat spinal-induced hypotension in cesarean deliveries: randomized controlled trial. Anesth Analg. 2019;129(5):1312–1318. doi:10.1213/ANE.0000000000003704
  • Belin O, Casteres C, Alouini S, et al. Manually controlled, continuous infusion of phenylephrine or norepinephrine for maintenance of blood pressure and cardiac output during spinal anesthesia for cesarean delivery: a double-blinded randomized study. Anesth Analg. 2023;136(3):540–550. doi:10.1213/ANE.0000000000006244
  • Vallejo MC, Attaallah AF, Elzamzamy OM, et al. An open-label randomized controlled clinical trial for comparison of continuous phenylephrine versus norepinephrine infusion in prevention of spinal hypotension during cesarean delivery. Int J Obstet Anesth. 2017;29:18–25. doi:10.1016/j.ijoa.2016.08.005
  • Fitzgerald JP, Fedoruk KA, Jadin SM, et al. Prevention of hypotension after spinal anaesthesia for caesarean section: a systematic review and network meta-analysis of randomised controlled trials. Anaesthesia. 2020;75(1):109–121. doi:10.1111/anae.14841
  • Dyer RA, Emmanuel A, Adams SC, et al. A randomised comparison of bolus phenylephrine and ephedrine for the management of spinal hypotension in patients with severe preeclampsia and fetal compromise. Int J Obstet Anesth. 2018;33:23–31. doi:10.1016/j.ijoa.2017.08.001
  • Heesen M, Rijs K, Hilber N, et al. Ephedrine versus phenylephrine as a vasopressor for spinal anaesthesia-induced hypotension in parturients undergoing high-risk caesarean section: meta-analysis, meta-regression and trial sequential analysis. Int J Obstet Anesth. 2019;37:16–28. doi:10.1016/j.ijoa.2018.10.006