66
Views
3
CrossRef citations to date
0
Altmetric
Original Research

Identification of PPARγ ligands with One-dimensional Drug Profile Matching

, , , , , , , , & show all
Pages 917-928 | Published online: 02 Sep 2013

References

  • Paul SM Mytelka DS Dunwiddie CT How to improve R&D productivity: the pharmaceutical industry’s grand challenge Nat Rev Drug Discov 2010 9 3 203 214 20168317
  • Simon Z Peragovics A Vigh-Smeller M Drug effect prediction by polypharmacology-based interaction profiling J Chem Inf Model 2012 52 1 134 145 22098080
  • Peragovics Á Simon Z Tombor L Virtual affinity fingerprints for target fishing: a new application of Drug Profile Matching J Chem Inf Model 2013 53 1 103 113 23215025
  • Peragovics A Simon Z Brandhuber I Contribution of 2D and 3D structural features of drug molecules in the prediction of drug profile matching J Chem Inf Model Epub 6 29 2012
  • Patel CB De Lemos JA Wyne KL McGuire DK Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPar gamma agonism Diab Vasc Dis Res 9 2006 3 2 65 71 17058625
  • Saltiel AR Olefsky JM Thiazolidinediones in the treatment of insulin resistance and type II diabetes Diabetes 1996 45 12 1661 1669 8922349
  • Kohlroser J Mathai J Reichheld J Banner BF Bonkovsky HL Hepatotoxicity due to troglitazone: report of two cases and review of adverse events reported to the United States Food and Drug Administration Am J Gastroenterol 2000 95 1 272 276 10638596
  • Nissen SE Wolski K Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality Arch Intern Med 2010 170 14 1191 1201 20656674
  • Lewis JD Ferrara A Peng T Risk of bladder cancer among diabetic patients treated with pioglitazone: interim report of a longitudinal cohort study Diabetes Care 2011 34 4 916 922 21447663
  • Wishart DS Knox C Guo AC DrugBank: a knowledgebase for drugs, drug actions and drug targets Nucleic Acids Res 2008 36 Database issue D901 D906 18048412
  • Berman HM Westbrook J Feng Z The protein data bank Nucleic Acids Res 2000 28 1 235 242 10592235
  • Morris GM Huey R Olson AJ Using AutoDock for ligand-receptor docking Curr Protoc Bioinformatics 2008 Chapter 8 Unit 8.14
  • Jiang X Kumar K Hu X Wallqvist A Reifman J DOVIS 2.0: an efficient and easy to use parallel virtual screening tool based on AutoDock 4.0 Chem Cent J 2008 2 18 18778471
  • Huey R Morris GM Olson AJ Goodsell DS A semiempirical free energy force field with charge-based desolvation J Comput Chem 2007 28 6 1145 1152 17274016
  • Morris GM Huey R Lindstrom W AutoDock4 and AutoDockTools4: automated docking with selective receptor flexibility J Comput Chem 2009 30 16 2785 2791 19399780
  • Qian G Sural S Gu Y Pramanik S Similarity between Euclidean and cosine angle distance for nearest neighbor queries Journal of the American Society for Information Science 1999 60 9 772 778
  • Graves RA Tontonoz P Spiegelman BM Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression Mol Cell Biol 1992 12 3 1202 1208 1545801
  • Reed MJ Meszaros K Entes LJ A new rat model of type 2 diabetes: the fat-fed, streptozotocin-treated rat Metab Clin Exp 2000 49 11 1390 1394 11092499
  • Li X Brasseur P Agnamey P Long-lasting anticryptosporidial activity of nitazoxanide in an immunosuppressed rat model Folia Parasitol 2003 50 1 19 22 12735719
  • Peitl B Döbrönte R Drimba L Involvement of cholecystokinin in baseline and post-prandial whole body insulin sensitivity in rats Eur J Pharmacol 2010 644 1–3 251 256 20624386
  • DeFronzo RA Tobin JD Andres R Glucose clamp technique: a method for quantifying insulin secretion and resistance Am J Physiol 1979 237 3 E214 E223 382871
  • Sherwin RS Kramer KJ Tobin JD A model of the kinetics of insulin in man J Clin Invest 1974 53 5 1481 1492 4856884
  • Wallenstein S Zucker CL Fleiss JL Some statistical methods useful in circulation research Circ Res 1980 47 1 1 9 7379260
  • Peitl B Németh J Pankucsi C Szilvássy Z Insulin sensitization induced by oral cicletanine in conscious rabbits Naunyn Schmiedebergs Arch Pharmacol 2006 373 6 429 439 16955283
  • Danaei G Finucane MM Lu Y Singh GM Cowan MJ Paciorek CJ National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants Lancet 2011 378 9785 31 40 21705069
  • Mudaliar S Chang AR Henry RR Thiazolidinediones, peripheral edema, and type 2 diabetes: incidence, pathophysiology, and clinical implications Endocr Pract 2003 9 5 406 416 14583425
  • Nesto RW Bell D Bonow RO Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association Diabetes Care 2004 27 1 256 263 14693998
  • Loke YK Singh S Furberg CD Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis CMAJ 2009 180 1 32 39 19073651
  • Zhang F Lavan BE Gregoire FM Selective modulators of PPAR-gamma activity: molecular aspects related to obesity and side-effects PPAR Res 2007 2007 32696 17389769
  • Higgins LS Depaoli AM Selective peroxisome proliferator-activated receptor gamma (PPARgamma) modulation as a strategy for safer therapeutic PPARgamma activation Am J Clin Nutr 2010 91 1 267S 272S 19906796
  • Kramer D Shapiro R Adler A Bush E Rondinone CM Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats Metab Clin Exp 2001 50 11 1294 1300 11699047
  • Chakrabarti R Vikramadithyan RK Misra P Ragaglitazar: a novel PPAR alpha PPAR gamma agonist with potent lipid-lowering and insulin-sensitizing efficacy in animal models Br J Pharmacol 2003 140 3 527 537 12970088
  • Hoffman PS Sisson G Croxen MA Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni Antimicrob Agents Chemother 2007 51 3 868 876 17158936
  • Rossignol JF La Frazia S Chiappa L Ciucci A Santoro MG Thiazolides, a new class of anti-influenza molecules targeting viral hemagglutinin at the post-translational level J Biol Chem 2009 284 43 29798 29808 19638339
  • Murphy JR Friedmann JC Pre-clinical toxicology of nitazoxanide – a new antiparasitic compound J Appl Toxicol 1985 5 2 49 52 3889119