References
- GeertsWBergquistDPineoFPrevention of venous thromboembolism. American College of Chest Physicians’ evidence-based clinical practice guidelines (8th ed)Chest2008133381S453S18574271
- CohenATTapsonVFBergmannJFVenous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): A multinational cross-sectional studyLancet200837138739418242412
- HeitJAVenous thromboembolism: Disease burden, outcomes and risk factorsJ Thromb Haemost200531611161716102026
- SeagroattVTanHSGoldcreMElective total hip replacement: Incidence, emergency readmission rate and postoperative mortalityBMJ1991303143114351773147
- DahlOECapriniJAColwellCWFatal vascular outcomes following major orthopedic surgeryThromb Haemost20059386086615886800
- PellegriniVDonaldsonCFarberDLehmanEEvartsCThe John Charnley Award: Prevention of readmission for venous thromboembolism disease after total hip arthroplastyClin Orthop2005441566216330984
- DahlOEGudmundsenTEHaukelandLLate occurring clinical deep vein thrombosis in joint-operated patientsActa Orthop Scand200071475010743992
- HeitJASilversteinMDMohrDNRisk factors for deep vein thrombosis and pulmonary embolism: A population based case-control studyArch Intern Med200016080981510737280
- AndersonFAWheelerHBGoldbergRJA population based perspective of the hospital incidence and case fatality rates of deep vein thrombosis and pulmonary embolism: The Worcester DVT studyArch Intern Med19911519339382025141
- SamamaMCohenATDarmonJYA comparison of enoxaparin with placebo for the prevention of venous thromboembolism in acutely ill medical patientsN Engl J Med199934179380010477777
- WeitzJHirshJSamamaMMNew anticoagulant drugsChest2004126265S286S15383475
- PrandoniPFalangaAPiccioliACancer and venous thromboembolismLancet Oncology2005640141015925818
- KhoranaAFrancisCCulakovaEThromboembolism is leading cause of death in cancer patients receiving outpatient chemotherapyJ Thromb Haemost2007563263417319909
- HeitJSilversteinMMohrDPettersonTO’FallonWMeltonLJRisk factors for deep vein thrombosis and pulmonary embolism: A population based case-control studyArch Intern Med200016080981510737280
- AgnelliGGussoniGBianchiniCNadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: A randomised, placebo-controlled, double-blind studyLancet Oncol20091094394919726226
- GallusASPrevention of postoperative deep leg vein thrombosis in patients with cancerThromb Haemost1997781261329198141
- FurieBFurieBCMolecular and cellular biology of blood coagulationN Engl J Med19923268008061538724
- MannKButenasSBrummelKThe dynamics of thrombin formationArterioscler Thromb Vasc Biol200323172512524220
- KubitzaDBeckaMWensingGVoithBZuehlsdorfMSafety, pharmacodynamics and pharmacokinetics of BAY 59-7939, an oral, direct, Factor Xa inhibitor after multiple dosing in healthy male subjectsEur J Clin Pharmacol20056187388016328318
- KubitzaDBeckaMRothAMueckWDose escalation study of the pharmacokinetics and pharmacodynamics of rivaroxaban in healthy elderly subjectsCurr Med Res Opin2008242757276518715524
- WeinzCSchwartzTPleissJMetabolism and distribution of BAY 59-7939 – an oral, direct factor Xa inhibitor - in rat, dog and humanDrug Metab Rev200436196
- SpyropoulosACBrave new world: The current and future use of novel anticoagulantsThrombosis Research200812329S35S
- RaghavanNFrostCEYuZApixaban metabolism and pharmacokinetics after oral administration to humansDrug Metabolism and Disposition Fast Forward2009377481
- KanHBingHGraceJEPreclinical pharmacokinetics and metabolism of apixaban, a potent and selective factor Xa inhibitorBlood2006108273
- TurpieAGGNew oral anticoagulants in atrial fibrillationEur Heart J20082915516518096568
- ZafarMVorcheimerDGaztanagaJAntithombotic effects of factor Xa inhibition with DU-176b: Phase I study of an oral direct factor Xa inhibitor using an ex-vivo flow chamberThromb Haemost20079888388817938815
- ErikssonBTurpieALassenMA dose escalation study of YM150, an oral direct factor Xa inhibitor, in the prevention of venous thromboembolism in elective primary hip replacementJ Thromb Haemost200751660166517663737
- AgnelliGHaasSGinsbergJKruegerKDmitrienkoABrandtJA phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacementJ Thromb Haemost2007574675317408408
- LassenMDavidsonBGallusAA Phase II randomized double blind, five-arm, parallel group, dose response study of a new oral acting Factor Xa inhibitor, razaxaban, for the prevention of deep vein thrombosis in knee replacement surgeryBlood200310215
- CohenAArmstrongDGazdzikTAn adaptative-design doseranging study of PD 0348292, a new oral factor Xa inhibitor, for the prophylaxis after total knee replacement surgeryBlood2008112 Abstr 980
- StangierJRathgenKStahleHGansserDRothWThe pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjectsBr J Clin Pharmacol20076429230317506785
- LassenMDahlOMismettiPDestréeDTurpieAGAVE5026, a new hemisynthetic ultra-low-molecular-weight heparin for the prevention of venous thromboembolism in patients after total knee replacement surgery-TREK: A dose-ranging studyJ Thromb Haemost2009756657219187076
- PerzbornEFactor Xa inhibitors. New anticoagulants for secondary haemostasisHamostaseologie20092926026719644596
- TurpieAFisherWBauerKBAY 59-7939: An oral, direct factor Xa inhibitor for the prevention of venous thromboembolism in patients after total knee replacement. A phase II dose-ranging studyJ Thromb Haemost200532479248616241946
- ErikssonBIBorrisLDahlOEOral, direct Factor Xa inhibition with BAY 59-7939 for the prevention of venous thromboembolism after total hip replacementJ Thromb Haemost2006412112816409461
- ErikssonBIBorrisLDahlOEA once-daily oral, direct Factor Xa inhibitor, Rivaroxaban (BAY 59-7939), for thromboprophylaxis after total hip replacementCirculation20061142374238117116766
- ErikssonBIBorrisLCFriedmanRJRivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplastyN Engl J Med20083582765277518579811
- LassenMRAgenoWBorrisLCRivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplastyN Engl J Med200835826
- KakkarAKBrennerBDahlOEExtended duration rivaroxaban versus short-term enoxaparin for the prevention of venous thromboembolism after total hip arthroplasty: A double-blind, randomised controlled trialLancet20083723539
- TurpieALassenMDavidsonBRivaroxaban versus enoxaparin for thromboprophylaxis after total knee arthroplasty (RECORD 4): A randomized trialLancet20093731673168019411100
- BauerKATurpieAGGLassenMRKakkarAKErikssonBIGentMEffect on age, weight, gender and renal function in a pooled analysis of four rivaroxaban studies. [abstract]J Thromb Haemost2009
- TurpieAGGLassenMRKakkarAKErikssonBIGentMPooled analysis of four rivaroxaban studies: effects on symptomatic events and bleeding. [abstract]Blood2008San Francisco CA
- Van ThielDKalodikiEWahiRLitinasEHaqueWRaoGInterpretation of benefit-risk of enoxaparin as comparator in the RECORD program: Rivaroxaban oral tablets (10 mg) for use in prophylaxis in deep vein thrombosis and pulmonary embolism in patients undergoing hip or knee replacement surgeryClin Appl Thromb Haemost200915389394
- LassenMRDavidsonBLGallusAPineoGAnsellJDeitchmanDThe efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacementJ Thromb Haemost200752368237517868430
- LassenMRRaskobGEGallusAPineoGChenDPortmanRJApixaban or enoxaparin for thromboprophylaxis after knee replacementN Engl J Med200936159460419657123
- LassenMGallusAPineoGRaskobGThe advance-2 study: A randomized double-blind trial comparing apixaban with enoxaparin for thromboprophylaxis after total knee replacement. [abstract]J Thromb Haemost2009
- TurpieABauerKDavidsonBA randomized evaluation of betrixaban, an oral factor Xa inhibitor for prevention of thrombolic events after total knee replacement (EXPERT)Thromb Haemost2009101687619132191
- FujiTFujitaSTachibanaSRandomized, double-blind, multidose efficacy, safety and biomarker study of the oral factor Xa inhibitor DU-176b compared with placebo for prevention of venous thromboembolism in patients after total knee arthroplastyBlood20081123418436740
- RaskobGCohenAErikssonBRandomized double-blind multidose trial of the oral factor Xa inhibitor DU-176b versus LMW heparin (dalteparin) for prevention of venous thromboembolism after total hip replacementEur Heart J20082960918310671
- ErikssonBITurpieAGLassenMRPrevention of venous thromboembolism with an oral Factor Xa inhibitor, YM150, after total hip arthroplasy. A dose-finding study (ONYX-2)J Thromb Haemost2010 Epub ahead of print. Blood. 2007;110:A309
- ErikssonBIDahlOEAhnfeltLKäleboPDose escalating safety study of a new oral direct thrombin inhibitor, dabigatran etexilate, in patients undergoing total hip replacement: BISTRO IThromb Haemost2004215731580
- ErikssonBIDahlOEBüllerHRHettiarachchiRA new oral direct thrombin inhibitor, dabigatran etexilate, compared with enoxaparin for prevention of thromboembolic events following total hip or knee replacement: The BISTRO II randomized trialJ Thromb Haemost2005310311115634273
- ErikssonBIDahlOERosencherNDabigatran etexilate versus enoxaparin for prevention of venous thromboembolism after total hip replacement: A randomised, double-blind, non-inferiority trialLancet200737094995617869635
- ErikssonBIDahlOERosencherNDabigatran etexilate versus enoxaparin for the prevention of venous thromboembolism after total knee replacement: The RE-MODEL randomized trialJ Thromb Haemost200752178218517764540
- The RE-MOBILIZE Writing CommitteeOral thrombin inhibitor dabigatran etexilate vs North American enoxaparin regime for prevention of venous thromboembolism after knee arthroplasty surgeryThe Journal of Arthroplasty2009241
- WolowaczSERoskellNSPlumbJMCapriniJAErikssonBIEfficacy and safety of dabigatran etexilate for the prevention of venous thromboembolism following total hip or knee arthroplasty. A meta-analysisThromb Haemost2009101778519132192
- AgnelliGBergqvistDCohenAGallusASGentMA randomized double-blind study to compare the efficacy and safety of fondaparinux with dalteparin in the prevention of venous thromboembolism after high risk abdominal surgery: The PEGASUS studyBr J Surg2006106347352
- Di CarloVAgnelliGPrandoniPDermatan sulphate for the prevention of postoperative venouse thromboembolism in patients with cancer. DOS (Dermatan sulphate in Oncologic Surgery) Study GroupThromb Haemost199982303410456450
- ENOXACAN Study GroupEfficacy and safety of enoxaparin versus unfractionated heparin for prevention of deep vein thrombosis in elective cancer surgery: A double-blind randomized multicentre trial with venographic assessmentBr J Surg199784109911039278651
- BergqvistDAgnelliGCohenATFor ENOXACAN II InvestigatorsDuration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancerN Engl J Med200234697598011919306