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Original Research

The mechanism of CCN1-enhanced retinal neovascularization in oxygen-induced retinopathy through PI3K/Akt–VEGF signaling pathway

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Pages 2463-2473 | Published online: 30 Apr 2015

References

  • Nowak-SliwinskaPStortoMCataudellaTAngiogenesis inhibition by the maleimide-based small molecule GNX-686Microvasc Res201283210511022056402
  • SemeraroFMorescalchiFDuseSParmeggianiFGanmbicortiECostagliolaCAflibercept in wet AMD: specific role and optimal useDrug Des Devel Ther20137711722
  • ChenJStahlAHellstromASmithLECurrent update on retinopathy of prematurity: screening and treatmentCurr Opin Pediatr201123217317821150442
  • HasanAPokezaNShawLThe matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathyJ Biol Chem2011286119542955421212276
  • AdamisAPShimaDTThe role of vascular endothelial growth factor in ocular health and diseaseRetina200525211111815689799
  • MiXSYuanTFDingYZhongJXSoXFChoosing preclinical study models of diabetic retinopathy: key problems for considerationDrug Des Devel Ther2014823112319
  • SatoTKusakaSShimojoHFujikadoTVitreous levels of erythropoietin and vascular endothelial growth factor in eyes with retinopathy of prematurityOphthalmology200911691599160319371954
  • KuiperEJHughesJMVan GeestRJEffect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retinaInvest Ophthalmol Vis Sci20074894267427617724216
  • LeaskACCN1: a novel target for pancreatic cancerJ Cell Commun Signal20115212312421484184
  • ChaqourBNew Insights into the Function of the Matricellular CCN1: an Emerging Target in Proliferative RetinopathiesJ Ophthalmic Vis Res201381778223825719
  • Borkham-KamphorstESchaffrathCVan de LeurEThe anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signalingBiochim Biophys Acta20141843590291424487063
  • YouJJYangCHYangCMChenMSCyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin alphanubeta3, FAK, PI3K/Akt, and NF-kappaB pathways in retinal vascular endothelial cellsCell Signal201426113314024063814
  • KoonHWShihDQHingTCSubstance P induces CCN1 expression via histone deacetylase activity in human colonic epithelial cellsAm J Pathol201117952315232621945803
  • SmithLEWesolowskiEMcLellanAOxygen-induced retinopathy in the mouseInvest Ophthalmol Vis Sci19943511011117507904
  • TolentinoMMcleodDSTaomotoMOtsujiTAdamisAPLuttyGAPathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primateAm J Ophthalmol2002133337338511860975
  • ChikaraishiYShimazawaMHaraHNew quantitative analysis, using high-resolution images, of oxygen-induced retinal neovascularization miceExp Eye Res200784352953617208227
  • ParkKChenYHuYNanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemia-induced retinal neovascularization and diabetes-induced retinal vascular leakageDiabetes20095881902191319491211
  • LivakKJSchmittgenTDAnalysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) MethodMethods200125440240811846609
  • JiangJXiaXBXuHZInhibition of retinal neovascularization by gene transfer of small interfering RNA targeting HIF-1a and VEGFJ Cell Physiol20092181667418767037
  • JinYAnXYeZCullyBWuJLiJRGS5, a hypoxia-inducible apoptotic stimulator in endothelial cellsJ Biol Chem200928435234362344319564336
  • ParkSWKimJHKimKEBeta-lapachone inhibitspathological retinal neovascularization in oxygen-induced retinopathy via regulation of HIF-1αJ Cell Mol Med201418587588424533641
  • Pakzad-VaeziKAlbianiDAKirkerAWA randomized study comparing the efficacy of bevacizumab and ranibizumab as pre-treatment for pars plana vitrectomy in proliferative diabetic retinopathyOphthalmic Surg Lasers Imaging Retina201445652152425423631
  • HuJHoangQVChauFYBlairMPLimJIIntravitreal anti-vascular endothelial growth factor for choroidal neovascularization in ocular histoplasmosisRetin Cases Brief Rep201481242925372202
  • Mintz-HittnerHAKennedyKAChuangAZBEAT-ROP Cooperative GroupEfficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurityN Engl J Med2011364760361521323540
  • VanhaesebrouckSDaniëlsHMoonsLVanholeCCarmelietPDe ZegherFOxygen-induced retinopathy in mice: amplification by neonatal IGF-I deficit and attenuation by IGF-I administrationPediatr Res200965330731019092722
  • LinMChenYJinJIschaemia-induced retinal neovascularisation and diabetic retinopathy in mice with conditional knockout of hypoxia-inducible factor-1 in retinal Müller cellsDiabetologia20115461554156621360191
  • YanLChaqourBCysteine-rich protein 61 (CCN1) and connective tissue growth factor (CCN2) at the crosshairs of ocular neovascular and fibrovascular disease therapyJ Cell Commun Signal20137425326323740088
  • ChoiJLinAShrierELauLFGrantMBChaqourBDegradome products of the matricellular protein CCN1 as modulators of pathological angiogenesis in the retinaJ Biol Chem201328832230752308923798676
  • RenFFanMMeiJInterferon-gamma and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironmentDrug Des Devel Ther2014815271538
  • BabicAMKireevaMLKolesnikovaTVLauLFCYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growthProc Natl Acad Sci U S A19989511635563609600969
  • YouJJYangCHChenMSYangCMCysteine-rich 61, a member of the CCN family, as a factor involved in the pathogenesis of proliferative diabetic retinopathyInvest Ophthalmol Vis Sci20095073447345519264885
  • ZhangXYuWDongFCysteine-rich 61 (CYR61) is up-regulated in proliferative diabetic retinopathyGraefes Arch Clin Exp Ophthalmol2012250566166822160564
  • HanrahanFHumphriesPCampbellMRNAi-mediated barrier modulation: synergies of the brain and eyeTher Deliv20101458759422833969
  • MasudaIMatsuoTYasudaTMatsuoNGene transfer with liposomes to the intraocular tissues by different routes of administrationInvest Ophthalmol Vis Sci1996379191419208759362
  • NariseKOkudaKEnomotoYHirayamaTNagasawaHOptimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironmentDrug Des Devel Ther20148701717
  • YouJJYangCMChenMSYangCHRegulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1alpha in retinal vascular endothelial cellsExp Eye Res201091682583621029732