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Review

The interplay of post-translational modification and gene therapy

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Pages 861-871 | Published online: 29 Feb 2016

References

  • KouzaridesTChromatin modifications and their functionCell200712869370517320507
  • ErkmannJHistone modification research methodsMater Methods2011192
  • FengQZhangYThe MeCP1 complex represses transcription through preferential binding, remodeling, and deacetylating methylated nucleosomesGenes Dev20011582783211297506
  • BergerSLThe complex language of chromatin regulation during transcriptionNature200744740741217522673
  • Antizar-LadislaoBEnvironmental levels, toxicity and human exposure to tributyltin (TBT)-contaminated marine environment: a reviewEnviron Int20083429230817959247
  • BernsteinBEKamalMLindblad-TohKGenomic maps and comparative analysis of histone modifications in human and mouseCell200512016918115680324
  • FeinbergAPTyckoBThe history of cancer epigeneticsNat Rev Cancer2004414315314732866
  • WolffeAPMatzkeMAEpigenetics: regulation through repressionScience199928648148610521337
  • JauhariSRizviSAMMining gene expression data focusing cancer therapeutics: a digestIEEE/ACM Trans Comput Biol Bioinform20141153354726356021
  • StartekMLe RouzicACapyPGrzebelusDGambinAGenomic parasites or symbionts? Modeling the effects of environmental pressure on transposition activity in asexual populationsTheor Popul Biol20139014515123948701
  • FenauxPMuftiGJHellström-LindbergEAzacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemiaJ Clin Oncol20102856256920026804
  • ZhangLThrasherAJGasparHBCurrent progress on gene therapy for primary immunodeficienciesGene Ther20132096396923719067
  • CancioMIReissUMNathwaniACDavidoffAMGrayJTDevelopments in the treatment of hemophilia B: focus on emerging gene therapyAppl Clin Genet201369110124159262
  • NathwaniACRosalesCMcIntoshJLong-term safety and efficacy following systemic administration of a self-complementary AAV vector encoding human FIX pseudotyped with serotype 5 and 8 capsid proteinsMol Ther20111987688521245849
  • MannoCSChewAJHutchisonSAAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia BBlood20031012963297212515715
  • BuchlisGPodsakoffGMRaduAFactor IX expression in skeletal muscle of a severe hemophilia B patient 10 years after AAV-mediated gene transferBlood20121193038304122271447
  • MannoCSPierceGFArrudaVRSuccessful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune responseNat Med20061234234716474400
  • DavidoffAMGrayJTNgCYCComparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate modelsMol Ther20051187588815922958
  • HurlbutGDZieglerRJNietupskiJBPreexisting immunity and low expression in primates highlight translational challenges for liver-directed AAV8-mediated gene therapyMol Ther2010181983199420736932
  • VarnavskiANZhangYSchnellMPreexisting immunity to adenovirus in rhesus monkeys fails to prevent vector-induced toxicityJ Virol2002765711571911991999
  • SuzukiMBertinTKRogersGLDifferential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs adeno-associated viral vectors in vivoMol Ther20132179680523319058
  • VarnavskiANCalcedoRBoveMGaoGWilsonJMEvaluation of toxicity from high-dose systemic administration of recombinant adenovirus vector in vector-naïve and pre-immunized miceGene Ther20051242743615647774
  • ZhangXMathewsCKEffect of DNA cytosine methylation upon deamination-induced mutagenesis in a natural target sequence in duplex DNAJ Biol Chem1994269706670698125913
  • JinS-GJiangC-LRauchTLiHPfeiferGPMBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencingJ Biol Chem2005280127001270915701600
  • FujikaneRSanadaMSekiguchiMHidakaMThe identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O6-methylguaninePLoS One20127e4481723028632
  • RamsaySWRutherfordECurieMSSoddyFNobel Lectures Including Presentation Speeches and Laureates’ Biographies: Chemistry 1901–1921Amsterdam, the NetherlandsElsevier1966
  • StedmanEStedmanECell specificity of histonesNature195016678078114780242
  • FelsenfeldGA brief history of epigeneticsCold Spring Harb Perspect Biol20146a01820024384572
  • AllfreyVGFaulknerRMirskyAEAcetylation and methylation of histones and their possible role in the regulation of RNA synthesisProc Natl Acad Sci U S A19645178679414172992
  • KornbergRDChromatin structure: a repeating unit of histones and DNAScience19741848688714825889
  • HershkoAThe ubiquitin system for protein degradation and some of its roles in the control of the cell division cycle (Nobel Lecture)Cell Death Differ2005121191119716094395
  • WallisJWHerefordLGrunsteinMHistone H2B genes of yeast encode two different proteinsCell1980227998057006833
  • RichmondTJFinchJTRushtonBRhodesDKlugAStructure of the nucleosome core particle at 7 Å resolutionNature19843115325376482966
  • DurrinLKMannRKKaynePSGrunsteinMYeast histone H4 N-terminal sequence is required for promoter activation in vivoCell199165102310312044150
  • LugerKMäderAWRichmondRKSargentDFRichmondTJCrystal structure of the nucleosome core particle at 2.8 A resolutionNature19973892512609305837
  • ChuCQuinnJChangHYChromatin isolation by RNA purification (ChIRP)J Vis Exp201225391222472705
  • PasqueVHalley-StottRPGillichAGarrettNGurdonJBEpigenetic stability of repressed states involving the histone variant macroH2A revealed by nuclear transfer to Xenopus oocytesNucleus2011253353922064467
  • JenuweinTAllisCDTranslating the histone codeScience20012931074108011498575
  • SchreiberSLBernsteinBESignaling network model of chromatinCell200211177177812526804
  • TurnerBMCellular memory and the histone codeCell200211128529112419240
  • SutendraGKinnairdADromparisPA nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylationCell2014158849724995980
  • LiYWenHXiYAF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylationCell201415955857125417107
  • MargueronRReinbergDThe polycomb complex PRC2 and its mark in lifeNature201146934334921248841
  • HansenKHBrackenAPPasiniDA model for transmission of the H3K27me3 epigenetic markNat Cell Biol2008101291130018931660
  • MargueronRLiGSarmaKEzh1 and Ezh2 maintain repressive chromatin through different mechanismsMol Cell20083250351819026781
  • MargueronRJustinNOhnoKRole of the polycomb protein EED in the propagation of repressive histone marksNature200946176276719767730
  • GrossniklausUParoRTranscriptional silencing by polycomb-group proteinsCold Spring Harb Perspect Biol20146a01933125367972
  • BannisterAJZegermanPPartridgeJFSelective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domainNature200141012012411242054
  • LachnerMO’CarrollDReaSMechtlerKJenuweinTMethylation of histone H3 lysine 9 creates a binding site for HP1 proteinsNature200141011612011242053
  • NakayamaJRiceJCStrahlBDAllisCDGrewalSIRole of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assemblyScience200129211011311283354
  • BasnetHSuXBTanYTyrosine phosphorylation of histone H2A by CK2 regulates transcriptional elongationNature2014516753026727125252977
  • MoelleringRECravattBFFunctional lysine modification by an intrinsically reactive primary glycolytic metaboliteScience201334154955323908237
  • JohnsonESProtein modification by SUMOAnnu Rev Biochem20047335538215189146
  • PearceMJMintserisJFerreyraJGygiSPDarwinKHUbiquitin-like protein involved in the proteasome pathway of Mycobacterium tuberculosisScience20083221104110718832610
  • YangYLiC-CHWeissmanAMRegulating the p53 system through ubiquitinationOncogene2004232096210615021897
  • PickartCMEddinsMJUbiquitin: structures, functions, mechanismsBiochim Biophys Acta20041695557215571809
  • FlothoAMelchorFSumoylation: a regulatory protein modification in health and diseaseAnnu Rev Biochem201382135738523746258
  • SatpathySGuérillonCKimT-SSUMOylation of the ING1b tumor suppressor regulates gene transcriptionCarcinogenesis2014352214222324903338
  • FischerSDunbrackRLKarplusMCis-trans imide isomerization of the proline dipeptideJ Am Chem Soc19941161193111937
  • CamilloniCSahakyanABHollidayMJCyclophilin A catalyzes proline isomerization by an electrostatic handle mechanismProc Natl Acad Sci U S A2014111102031020824982184
  • HoweFSBoubriakISaleMJLysine acetylation controls local protein conformation by influencing proline isomerizationMol Cell20145573374425127513
  • MaedaYYoshinoTMatsunagaTIn vivo biotinylation of bacterial magnetic particles by a truncated form of Escherichia coli biotin ligase and biotin acceptor peptideAppl Environ Microbiol2010765785579020622127
  • McKinleyBASukhodoletsMVEscherichia coli RNA polymerase-associated SWI/SNF protein RapA: evidence for RNA-directed binding and remodeling activityNucleic Acids Res2007357044706017913745
  • BelenkyPBoganKLBrennerCNAD+ metabolism in health and diseaseTrends Biochem Sci200732121917161604
  • De HaanLHirstTRCholera toxin: a paradigm for multi-functional engagement of cellular mechanisms [Review]Mol Membr Biol200421779215204437
  • ChristophorouMACastelo-BrancoGOliveiraCSCitrullination regulates pluripotency and histone H1 binding to chromatinNature201450710410824463520
  • ChenYSprungRTangYLysine propionylation and butyrylation are novel post-translational modifications in histonesMol Cell Proteomics2007681281917267393
  • ChengZTangYChenYMolecular characterization of pro-pionyllysines in non-histone proteinsMol Cell Proteomics20098455218753126
  • PengCLuZXieZThe first identification of lysine malonylation substrates and its regulatory enzymeMol Cell Proteomics201110M111.01265821908771
  • XieZDaiJDaiLLysine succinylation and lysine malonylation in histonesMol Cell Proteomics20121110010722389435
  • TanMLuoHLeeSIdentification of 67 histone marks and histone lysine crotonylation as a new type of histone modificationCell20111461016102821925322
  • ZhangZTanMXieZDaiLChenYZhaoYIdentification of lysine succinylation as a new post-translational modificationNat Chem Biol20117586321151122
  • LiuZWangYGaoTCPLM: a database of protein lysine modificationsNucleic Acids Res201442Database issueD531D53624214993
  • McIntoshJLentingPJRosalesCTherapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variantBlood20131213335334423426947
  • AllayJASleepSLongSGood manufacturing practice production of self-complementary serotype 8 adeno-associated viral vector for a hemophilia B clinical trialHum Gene Ther20112259560421410419
  • KussiePHGorinaSMarechalVStructure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domainScience19962749489538875929
  • Hacein-Bey-AbinaSvon KalleCSchmidtMA serious adverse event after successful gene therapy for X-linked severe combined immunodeficiencyN Engl J Med200334825525612529469
  • ModlichUSchambachABrugmanMHLeukemia induction after a single retroviral vector insertion in Evi1 or Prdm16Leukemia2008221519152818496560
  • HoweSJMansourMRSchwarzwaelderKInsertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patientsJ Clin Invest20081183143315018688286
  • WanischKYáñez-MuñozRJIntegration-deficient lentiviral vectors: a slow coming of ageMol Ther2009171316133219491821
  • SchottJWHoffmannDMaetzigTImproved retroviral episome transfer of transcription factors enables sustained cell fate modificationGene Ther20142193894925102011
  • RogersGLMartinoATAslanidiGVInnate immune responses to AAV vectorsFront Microbiol2011219421954398
  • MartinoATSuzukiMMarkusicDMThe genome of self-complementary adeno-associated viral vectors increases toll-like receptor 9–dependent innate immune responses in the liverBlood20111176459646821474674
  • FaustSMBellPCutlerBJCpG-depleted adeno-associated virus vectors evade immune detectionJ Clin Invest20131232994300123778142
  • MartinoATBasner-TschakarjanEMarkusicDMEngineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cellsBlood20131212224223323325831