References
- SiegelRMaJZouZJemalACancer statistics, 2014CA Cancer J Clin201464192924399786
- WilliamsonSCHartleyAEHeerRA review of tasquinimod in the treatment of advanced prostate cancerDrug Des Devel Ther20137167174
- AnsariJHussainSAZarkarATanguayJSBlissJGlaholmJDocetaxel chemotherapy for metastatic hormone refractory prostate cancer as first-line palliative chemotherapy and subsequent re-treatment: Birmingham experienceOncol Rep200820489189618813832
- de BonoJSLogothetisCJMolinaAAbiraterone and increased survival in metastatic prostate cancerN Engl J Med2011364211995200521612468
- Southwest Oncology GroupBerryDLMoinpourCMJiangCSQuality of life and pain in advanced stage prostate cancer: results of a Southwest Oncology Group randomized trial comparing docetaxel and estramustine to mitoxantrone and prednisoneJ Clin Oncol200624182828283516782921
- JohnstoneRWRuefliAALoweSWApoptosis: a link between cancer genetics and chemotherapyCell2002108215316411832206
- LoweSWCeperoEEvanGIntrinsic tumour suppressionNature2004432701530731515549092
- AdamsJMCorySThe Bcl-2 apoptotic switch in cancer development and therapyOncogene20072691324133717322918
- CoutureFD’AnjouFDayROn the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applicationsBiomol Concepts20112542143822308173
- SeidahNGPratAThe biology and therapeutic targeting of the pro-protein convertasesNat Rev Drug Discov201211536738322679642
- TsujiAHashimotoEIkomaTInactivation of proprotein convertase, PACE4, by alpha1-antitrypsin Portland (alpha1-PDX), a blocker of proteolytic activation of bone morphogenetic protein during embryogenesis: evidence that PACE4 is able to form an SDS-stable acyl intermediate with alpha1-PDXJ Biochem1999126359160310467177
- YuasaKMasudaTYoshikawaCNagahamaMMatsudaYTsujiASubtilisin-like proprotein convertase PACE4 is required for skeletal muscle differentiationJ Biochem2009146340741519520771
- TsujiASakuraiKKiyokageESecretory proprotein convertases PACE4 and PC6A are heparin-binding proteins which are localized in the extracellular matrix. Potential role of PACE4 in the activation of proproteins in the extracellular matrixBiochim Biophys Acta2003164519510412535616
- YanaIWeissSJRegulation of membrane type-1 matrix metalloproteinase activation by proprotein convertasesMol Biol Cell20001172387240110888676
- DuboisCMBlanchetteFLapriseMHLeducRGrondinFSeidahNGEvidence that furin is an authentic transforming growth factor-beta1-converting enzymeAm J Pathol2001158130531611141505
- SunGGLuYFZhangJHuWNFilamin A regulates MMP-9 expression and suppresses prostate cancer cell migration and invasionTumour Biol20143543819382624390612
- HubbardFCGoodrowTLLiuSCExpression of PACE4 in chemically induced carcinomas is associated with spindle cell tumor conversion and increased invasive abilityCancer Res19975723522652319393739
- KangSZhaoYHuKmiR-124 exhibits antiproliferative and antiaggressive effects on prostate cancer cells through PACE4 pathwayProstate201474111095110624913567
- LonguespéeRCoutureFLevesqueCImplications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: Insights for PACE4 as a therapeutic targetTransl Oncol Epub201459
- D’AnjouFRouthierSPerreaultJPMolecular validation of PACE4 as a target in prostate cancerTransl Oncol20114315717221633671
- KleeEWBondarOPGoodmansonMKCandidate serum biomarkers for prostate adenocarcinoma identified by mRNA differences in prostate tissue and verified with protein measurements in tissue and bloodClin Chem201258359960922247499
- KueferRHoferMDAltugVSodium butyrate and tributyrin induce in vivo growth inhibition and apoptosis in human prostate cancerBr J Cancer200490253554114735205
- EstiloCLO-charoenratPTalbotSOral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysisBMC Cancer200991119138406
- KurokawaYMatobaRNakamoriSPCR-array gene expression profiling of hepatocellular carcinomaJ Exp Clin Cancer Res200423113514115149162
- DelicSLottmannNJetschkeKReifenbergerGRiemenschneiderMJIdentification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genesNeuropathol Appl Neurobiol201238220121221722156
- MahloogiHBassiDEKlein-SzantoAJMalignant conversion of non-tumorigenic murine skin keratinocytes overexpressing PACE4Carcinogenesis200223456557211960907
- TaitSWGreenDRMitochondria and cell death: outer membrane permeabilization and beyondNat Rev Mol Cell Biol201011962163220683470
- LaCasseECMahoneyDJCheungHHPlenchetteSBairdSKornelukRGIAP-targeted therapies for cancerOncogene200827486252627518931692
- SerranoMLSánchez-GómezMBravoMMYakarSLeRoithDDifferential expression of IGF-I and insulin receptor isoforms in HPV positive and negative human cervical cancer cell linesHorm Metab Res2008401066166718711691
- PetterssonFDalgleishAGBissonnetteRPColstonKWRetinoids cause apoptosis in pancreatic cancer cells via activation of RAR-gamma and altered expression of Bcl-2/BaxBr J Cancer200287555556112189556
- DufeyESepúlvedaDRojas-RiveraDHetzCCellular mechanisms of endoplasmic reticulum stress signaling in health and disease. 1. An overviewAm J Physiol Cell Physiol20143077C582C59425143348
- DuanZZhaoJFanXThe PERK-eIF2α signaling pathway is involved in TCDD-induced ER stress in PC12 cellsNeurotoxicology20144414915924932542
- CuiWYLiuYZhuYQSongTWangQSPropofol induces endoplasmic reticulum (ER) stress and apoptosis in lung cancer cell H460Tumour Biol20143565213521724510348
- LiuCYSchröderMKaufmanRJLigand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulumJ Biol Chem200027532248812488510835430
- SzegezdiELogueSEGormanAMSamaliAMediators of endoplasmic reticulum stress-induced apoptosisEMBO Rep20067988088516953201
- NordinNMajidNAHashimNMRahmanMAHassanZAliHMLiriodenine, an aporphine alkaloid from Enicosanthellum pulchrum, inhibits proliferation of human ovarian cancer cells through induction of apoptosis via the mitochondrial signaling pathway and blocking cell cycle progressionDrug Des Devel Ther2015914371448
- RodríguezLVillalobosXDakhelSPolypurine reverse Hoogsteen hairpins as a gene therapy tool against survivin in human prostate cancer PC3 cells in vitro and in vivoBiochem Pharmacol201386111541155424070653
- SwiftSLRiveraGCDussuptVEvaluating baculovirus as a vector for human prostate cancer gene therapyPLoS One201386e6555723755250
- KangSZhaoYHuKmiR-124 exhibits antiproliferative and antiaggressive effects on prostate cancer cells through PACE4 pathwayProstate201474111095110624913567
- YuasaKSuzueKNagahamaMMatsudaYTsujiATranscriptional regulation of subtilisin-like proprotein convertase PACE4 by E2F: possible role of E2F-mediated upregulation of PACE4 in tumor progressionGene20074021–210311017825503
- LapierreMSiegfriedGScamuffaNOpposing function of the proprotein convertases furin and PACE4 on breast cancer cells’ malignant phenotypes: role of tissue inhibitors of metalloproteinase-1Cancer Res200767199030903417909005
- LevesqueCCoutureFKwiatkowskaAPACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neo-vascularisationOncotarget2015663680369325682874