References
- FaderlSO’BrienSPuiCHAdult acute lymphoblasticleukemia: concepts and strategiesCancer201011651165117620101737
- PuiCHAcute lymphoblastic leukemia. IntroductionSemin Hematol20094611219100362
- PuiCHRellingMVDowningJRAcute lymphoblastic leukemiaN Engl J Med2004350151535154815071128
- VivancoISawyersCLThe phosphatidylinositol 3-kinase AKT pathway in human cancerNat Rev Cancer20022748950112094235
- EngelmanJALuoJCantleyLCThe evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismNat Rev Genet20067860661916847462
- CourtneyKDCorcoranRBEngelmanJAThe PI3K pathway as drug target in human cancerJ Clin Oncol20102861075108320085938
- SharmaALalKHandaSSStandardization of the Indian crude drug kalmegh by high-pressure liquid-chromatographic determination of andrographolidePhytochem Anal199233129131
- NanduriSNyavanandiVKThunuguntlaSSRSynthesis and structure-activity relationships of andrographolide analogues as novel cytotoxic agentsBioorg Med Chem Lett200414184711471715324893
- ZhaoFHeEQWangLLiuKAnti-tumor activities of andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF levelJ Asian Nat Prod Res200810546747318464090
- NaikSRHuleAEvaluation of immunomodulatory activity of an extract of andrographolides from Andographis paniculataPlanta Med200975878579119263340
- WiartCKumarKYusofMYHamimahHFauziZMSulaimanMAntiviral properties of ent-labdene diterpenes of Andrographis paniculata Nees, inhibitors of herpes simplex virus type 1Phytother Res200519121069107016372376
- TsaiHRYangLMTsaiWJChiouWFAndrographolide acts through inhibition of ERK1/2 andAkt phosphorylation to suppress chemotactic migrationEur J Pharmacol20044981–3455215363974
- Sukumari-RameshSBentleyJNLairdMDSinghNVenderJRDhandapaniKMDietary phytochemicals induce p53- and caspase-independent cell death in human neuroblastoma cellsInt J Dev Neurosci201129770171021704149
- ShiMD1LinHHChiangTATsaiLYTsaiSMLeeYCAndrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expressionChem Biol Interact2009180334435219426720
- CheungHYCheungSHLiJAndrographolide isolated from Andrographis paniculata induces cell cycle arrest and mitochondrial-mediated apoptosis in human leukemic HL-60 cellsPlanta Med20057121106111116395645
- ChenWFengLNieHZhengXAndrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition poreCarcinogenesis2012332190219822869602
- LuoGXCaiJLinJZAutophagy inhibition promotes gambogic acid-induced suppression of growth and apoptosis in glioblastoma cellsAsian Pac J Cancer Prev201213136211621623464433
- WongHCWongCCSagineeduSRLokeSCLajisNHStanslasJSRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cellsCell Biol Toxicol201430526928825070834
- YangSEvensAMPrachandSMitochondrial-mediated apoptosis in lymphoma cells by the diterpenoid lactone andrographolide, the active component of Andrographis paniculataClin Cancer Res201016194755476820798229
- HigginsGCDevenishRJBeartPMNagleyPAutophagic activity in cortical neurons under acute oxidative stress directly contributes to cell deathCell Mol Life Sci201168223725374021437645
- LiJZhangCJiangHChengJAndrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growthOnco Targets Ther2015842743525709476
- GongCXuCJiLWangZA novel semi-synthetic andrographolide analogue A5 inhibits tumor angiogenesis via blocking the VEGFR2-p38/ERK1/2 signal pathwayBiosci Trends20137523023624241173
- BassanRHoelzerDModern therapy of acute lymphoblastic leukemiaJ Clin Oncol201129553254321220592
- GómezAMMartínezCGonzálezMChemokines and relapses in childhood acute lymphoblastic leukemia: a role in migration and in resistance to antileukemic drugsBlood Cells Mol Dis201555322022726227851
- ManikamSDStanslasJAndrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosisJ Pharm Pharmacol2009611697819126299
- ZhouJZhangSOngCNShenHMCritical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cellsBiochem Pharmacol200672213214416740251
- LeeYCLinHHHsuCHWangCJChiangTAChenJHInhibitory effects of andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathwayEur J Pharmacol20106321–3233220097193
- QiMSElionEAMAP kinase pathwaysJ Cell Sci2005118163569357216105880
- SuCCChenJYDinZH13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppressionMar Drugs201412105295531525342459
- PratheeshkumarPKuttanGAndrographolide inhibits human umbilical vein endothelial cell invasion and migration by regulating MMP-2 and MMP-9 during angiogenesisJ Environ Pathol Toxicol Oncol2011301334121609314
- ChenYYHsiehCYJayakumarTAndrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascadeSci Rep20144565125007834
- YangSHWangSMSyuJPAndrographolide induces apoptosis of C6 glioma cells via the ERK-p53-caspase 7-PARP pathwayBiomed Res Int20147871882
- CastanedaCACortes-FunesHGomezHLCiruelosEMThe phosphatidyl inositol 3-kinase/AKT signaling pathway in breast cancerCancer Metastasis Rev201029475175920922461
- PanSTQinYZhouZWPlumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cellsDrug Des Devel Ther2015916011626