References
- KungHFThe β-amyloid hypothesis in Alzheimer’s disease: seeing is believingACS Med Chem Lett20123426526724936237
- NaslundJHaroutunianVMohsRCorrelation between elevated levels of amyloid beta-peptide in the brain and cognitive declineJAMA2000283121571157710735393
- HardyJCullenKAmyloid at the blood vessel wallNat Med200612775675716829930
- SelkoeDJThe origins of Alzheimer’s disease: a is for amyloidJAMA2000283121615161710735401
- KimJEChoHJKimDDBudesonide/cyclodextrin complex-loaded lyophilized microparticles for intranasal applicationDrug Dev Ind Pharm201440674374823547762
- ConstantinMBucatariuSHarabagiuVAscenziPFundueanuGDo cyclodextrins bound to dextran microspheres act as sustained delivery systems of drugs?Int J Pharm201446911924726631
- KhodagholiFEftekharzadehBMaghsoudiNRezaeiPFChitosan prevents oxidative stress-induced amyloid b formation and cytotoxicity in NT2 neurons: involvement of transcription factors Nrf2 and NF-κBMol Cell Biochem20103371–2395119844776
- AraiKKinumakiTFujitaTToxicity of chitosanBull Tokai Reg Fish Lab1968438994
- ElnaggarYSEtmanSMAbdelmonsifDAAbdallahOYIntranasal piperine-loaded chitosan nanoparticles as brain-targeted therapy in alzheimer’s disease: optimization, biological efficacy, and potential toxicityJ Pharm Sci2015104103544355626147711
- HwangSMChenCYChenSSChenJCChitinous materials inhibit nitric oxide production by activated RAW264.7 macrophagesBiochem Biophys Res Commun2000271122923310777707
- MoosmannBBehlCAntioxidants as treatment for neurodegenerative disordersExpert Opin Investig Drugs2002111014071435
- XieWXuPLiuQAntioxidant activity of water-soluble chitosan derivativesBioorg Med Chem Lett200111131699170111425541
- ZhangJTangQXuXLiNDevelopment and evaluation of a novel phytosome-loaded chitosan microsphere system for curcumin deliveryInt J Pharm2013448116817423524117
- MorrisRDevelopment of a water-maze procedure for studying spatial learning in the ratJ Neurosci Methods198411147606471907
- BrandeisRBrandysYYehudaSThe use of the Morris Water Maze in the study of memory and learningInt J Neurosci1989481–229692684886
- WuMNZhouLWWangZJColivelin ameliorates amyloid β peptide-induced impairments in spatial memory, synaptic plasticity, and calcium homeostasis in ratsHippocampus201525336337225332198
- HePDavisSSIllumLChitosan microspheres prepared by spray dryingInt J Pharm19991871536510502613
- SanderCMadsenKDHyrupBNielsenHMRantanenJJacobsenJCharacterization of spray dried bioadhesive metformin microparticles for oromucosal administrationEur J Pharm Biopharm2013853 Pt A68268823774184
- JensenDMCunDMaltesenMJFrokjaerSNielsenHMFogedCSpray drying of siRNA-containing PLGA nanoparticles intended for inhalationJ Control Release2010142113814519840823
- ChewNYChanHKUse of solid corrugated particles to enhance powder aerosol performancePharm Res200118111570157711758765
- MartínMJCalpenaACFernándezFMallandrichMGálvezPClaresBDevelopment of alginate microspheres as nystatin carriers for oral mucosa drug deliveryCarbohydr Polym201511714014925498619
- ZhangWFChenXGLiPWLiuCSHeQZPreparation and characterization of carboxymethyl chitosan and β-cyclodextrin microspheres by spray dryingDrying Technol2008261108115
- WasnikSParmarPSinghDRamAPreparation and characterization of floating drug delivery system of azithromycinActa Pol Pharm201269351552222594266
- El-SherbinyIMSmythHDControlled release pulmonary administration of curcumin using swellable biocompatible microparticlesMol Pharm20129226928022136259
- ZhangWFChenXGLiPWHeQZZhouHYPreparation and characterization of theophylline loaded chitosan/b-cyclodextrin microspheresJ Mater Sci Mater Med200819130531017597373
- XuFYinMWuYDingHSongFWangJEffects of drying methods on the preparation of dexamethasone-loaded chitosan microspheresBiomed Mater20149505500325135351
- DevrimBBozkırACanefeKPreparation and evaluation of poly(lactic-co-glycolic acid) microparticles as a carrier for pulmonary delivery of recombinant human interleukin-2: II. In vitro studies on aerodynamic properties of dry powder inhaler formulationsDrug Dev Ind Pharm201137111376138621548727
- SinsuebpolCChatchawalsaisinJKulvanichPPreparation and in vivo absorption evaluation of spray dried powders containing salmon calcitonin loaded chitosan nanoparticles for pulmonary deliveryDrug Des Dev Ther20137861873
- FengZQSunCGZhengZJHuZBMuDZZhangWFOptimization of spray-drying conditions and pharmacodynamics study of theophylline/chitosan/β-cyclodexitrin microspheresDrying Technol2015335565
- IyerRMAugsburgerLLPopeDGShahRDExtrusion/spheronization-effect of moisture content and spheronization time on pellet characteristicsPharm Dev Technol1996143253319552316
- LazcanoZSolisOBringasMEUnilateral injection of Aβ25-35 in the hippocampus reduces the number of dendritic spines in hyperglycemic ratsSynapse20146812585594
- DelobetteSPrivatAMauriceTIn vitro aggregation facilitates b-amyloid peptide – 25–35-induced amnesia in the ratEur J Pharmacol19973191149030890
- D’AgostinoGRussoRAvaglianoCCristianoCMeliRCalignanoAPalmitoylethanolamide protects against the amyloid-β25-35-induced learning and memory impairment in mice, an experimental model of Alzheimer diseaseNeuropsychopharmacology20123771784179222414817
- LiuYMLiZYHuHTenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivoPharmacol Biochem Behav2015128142225444865
- SchrottLMJacksonKYiPAcute oral bryostatin-1 administration improves learning deficits in the APP/PS1 transgenic mouse model of Alzheimer’s diseaseCurr Alzheimer Res2015121223125523423
- CondeJRStreitWJMicroglia in the aging brainJ Neuropathol Exp Neurol200665319920316651881
- MittalGCarswellHBrettRCurrieSKumarMNDevelopment and evaluation of polymer nanoparticles for oral delivery of estradiol to rat brain in a model of Alzheimer’s pathologyJ Control Release2011150222022821111014
- WegielJImakiHWangKCOrigin and turnover of microglial cells in fibrillar plaques of APPsw transgenic miceActa Neuropathol2003105439340212624793
- XueQSStreitWJMicroglial pathology in Down syndromeActa Neuropathol2011122445546621847625