Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives

References

• International Diabetes Federation IDF Diabetes Atlas 7th ed Brussels IDF 2015
   Google Scholar
• National Diabetes Information Clearinghouse DCCT and EDIC: the Diabetes Control and Complications Trial and follow-up study 2008 Available from: https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/dcct-edic-diabetes-control-complications-trial-follow-up-study/Documents/DCCT-EDIC_508.pdf Accessed July 19, 2017
   Google Scholar
• No authors listed Epidemiology of Diabetes Interventions and Complications (EDIC): design, implementation, and preliminary results of a long-term follow-up of the Diabetes Control and Complications Trial cohort Diabetes Care 1999 22 1 99 111 10333910
   PubMed Web of Science ®Google Scholar
• Domingueti CP Dusse LM Carvalho MG de Sousa LP Gomes KB Fernandes AP Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications J Diabetes Complications 2016 30 4 738 745 26781070
   PubMed Web of Science ®Google Scholar
• Balcıoğlu AS Müderrisoğlu H Diabetes and cardiac autonomic neuropathy: clinical manifestations, cardiovascular consequences, diagnosis and treatment World J Diabetes 2015 6 1 80 91 25685280
   PubMedGoogle Scholar
• Spallone V Ziegler D Freeman R Cardiovascular autonomic neuropathy in diabetes: clinical impact, assessment, diagnosis, and management Diabetes Metab Res Rev 2011 27 7 639 653 21695768
   PubMed Web of Science ®Google Scholar
• Stables CL Glasser RL Feldman EL Diabetic cardiac autonomic neuropathy: insights from animal models Auton Neurosci 2013 177 2 74 80 23562143
   PubMed Web of Science ®Google Scholar
• Freeman R Diabetic autonomic neuropathy Handb Clin Neurol 2014 126 63 79 25410215
   PubMedGoogle Scholar
• Dimitropoulos G Tahrani AA Stevens MJ Cardiac autonomic neuropathy in patients with diabetes mellitus World J Diabetes 2014 5 1 17 39 24567799
   PubMedGoogle Scholar
• O’Brien IA Mcfadden JP Corrall RJ The influence of autonomic neuropathy on mortality in insulin-dependent diabetes Q J Med 1991 79 290 495 502 1946930
   PubMedGoogle Scholar
• Navarro X Kennedy W Aeppli D Sutherland D Neuropathy and mortality in diabetes: influence of pancreas transplantation Muscle Nerve 1996 19 8 1009 1016 8756167
   PubMed Web of Science ®Google Scholar
• Chen HS Hwu CM Kuo BI Abnormal cardiovascular reflex tests are predictors of mortality in type 2 diabetes mellitus Diabet Med 2001 18 4 268 273 11437856
   PubMed Web of Science ®Google Scholar
• Kempler P Tesfaye S Chaturvedi N Autonomic neuropathy is associated with increased cardiovascular risk factors: the EURODIAB IDDM complications study Diabet Med 2002 19 11 900 909 12421426
   PubMed Web of Science ®Google Scholar
• Low PA Benrud-Larson LM Sletten DM Autonomic symptoms and diabetic neuropathy: a population-based study Diabetes Care 2004 27 12 2942 2947 15562211
   PubMed Web of Science ®Google Scholar
• Pop-Busui R Low PA Waberski BH Effects of prior intensive insulin therapy on cardiac autonomic nervous system function in type 1 diabetes mellitus: the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study (DCCT/EDIC) Circulation 2009 119 22 2886 2893 19470886
   PubMed Web of Science ®Google Scholar
• Pop-Busui R Cardiac autonomic neuropathy in diabetes: a clinical perspective Diabetes Care 2010 33 2 434 441 20103559
   PubMed Web of Science ®Google Scholar
• Eze C Onwuekwe I Ogunniyi A The frequency and pattern of cardiac autonomic neuropathy (CAN) in type 2 dm patients in a diabetic clinic in Enugu south-east Nigeria Niger J Med 2013 22 1 24 31 23441516
   PubMedGoogle Scholar
• Tahrani AA Dubb K Raymond NT Cardiac autonomic neuropathy predicts renal function decline in patients with type 2 diabetes: a cohort study Diabetologia 2014 57 6 1249 1256 24623102
   PubMed Web of Science ®Google Scholar
• Lerner A Bernabé-Ortiz A Ticse R Type 2 diabetes and cardiac autonomic neuropathy screening using dynamic pupillometry Diabet Med 2015 32 11 1470 1478 25761508
   PubMed Web of Science ®Google Scholar
• Mendivil C Kattah W Orduz A Tique C Cárdenas J Patiño J Neuropad for the detection of cardiovascular autonomic neuropathy in patients with type 2 diabetes J Diabetes Complications 2016 30 1 93 98 26525688
   PubMed Web of Science ®Google Scholar
• Razanskaite-Virbickiene D Danyte E Mockeviciene G Dobrovolskiene R Verkauskiene R Zalinkevicius R Can coefficient of variation of time-domain analysis be valuable for detecting cardiovascular autonomic neuropathy in young patients with type 1 diabetes: a case control study BMC Cardiovasc Disord 2017 17 1 34 28103812
   PubMed Web of Science ®Google Scholar
• Menon AS Dixit A Garg MK Girish R Cardiac autonomic neuropathy in patients with type 2 diabetes mellitus at high risk for foot ulcers Indian J Endocrinol Metab 2017 21 2 282 285 28459026
   PubMedGoogle Scholar
• Tahrani AA Altaf QA Piya MK Barnett AH Peripheral and autonomic neuropathy in South Asians and white Caucasians with type 2 diabetes mellitus: possible explanations for epidemiological differ-ences J Diabetes Res 2017 2017 1273789 28409160
   PubMed Web of Science ®Google Scholar
• Pop-Busui R Braffett BH Zinman B Cardiovascular autonomic neuropathy and cardiovascular outcomes in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study Diabetes Care 2017 40 1 94 100 27803120
   PubMed Web of Science ®Google Scholar
• Dimova R Tankova T Guergueltcheva V Risk factors for autonomic and somatic nerve dysfunction in different stages of glucose tolerance J Diabetes Complications 2017 31 3 537 543 27894750
   PubMed Web of Science ®Google Scholar
• Pfeifer MA Weinberg CR Cook DL Autonomic neural dysfunction in recently diagnosed diabetic subjects Diabetes Care 1984 7 5 447 453 6499637
   PubMed Web of Science ®Google Scholar
• Ziegler D Diabetic cardiovascular autonomic neuropathy: prognosis, diagnosis and treatment Diabetes Metab Rev 1994 10 4 339 383 7796704
   PubMed Web of Science ®Google Scholar
• Giacco F Brownlee M Oxidative stress and diabetic complications Circ Res 2010 107 9 1058 1070 21030723
   PubMed Web of Science ®Google Scholar
• No authors listed The effect of intensive diabetes therapy on measures of autonomic nervous system function in the Diabetes Control and Complications Trial (DCCT) Diabetologia 1998 41 4 416 423 9562345
   PubMed Web of Science ®Google Scholar
• Boulton AJ Vinik AI Arezzo JC Diabetic neuropathies: a statement by the American Diabetes Association Diabetes Care 2005 28 4 956 962 15793206
   PubMed Web of Science ®Google Scholar
• Witte DR Tesfaye S Chaturvedi N Risk factors for cardiac autonomic neuropathy in type 1 diabetes mellitus Diabetologia 2005 48 1 164 171 15619072
   PubMed Web of Science ®Google Scholar
• Chung JO Park SY Cho DH Chung DJ Chung MY Anemia, bilirubin, and cardiovascular autonomic neuropathy in patients with type 2 diabetes Medicine (Baltimore) 2017 96 15 e6586 28403090
   PubMed Web of Science ®Google Scholar
• Valensi P Pariès J Attali JR Cardiac autonomic neuropathy in diabetic patients: influence of diabetes duration, obesity, and microangiopathic complications – the French multicenter study Metabolism 2003 52 7 815 820 12870154
   PubMed Web of Science ®Google Scholar
• Maser RE Lenhard MJ Cardiovascular autonomic neuropathy due to diabetes mellitus: clinical manifestations, consequences, and treatment J Clin Endocrinol Metab 2005 90 10 5896 5903 16014401
   PubMed Web of Science ®Google Scholar
• Ko SH Park SA Cho JH Progression of cardiovascular autonomic dysfunction in patients with type 2 diabetes: a 7-year follow-up study Diabetes Care 2008 31 9 1832 1836 18509202
   PubMed Web of Science ®Google Scholar
• Huang CC Lee JJ Lin TK Diabetic retinopathy is strongly predictive of cardiovascular autonomic neuropathy in type 2 diabetes J Diabetes Res 2016 2016 6090749 26955641
   PubMed Web of Science ®Google Scholar
• Pop-Busui R Evans GW Gerstein HC Effects of cardiac autonomic dysfunction on mortality risk in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial Diabetes Care 2010 33 7 1578 1584 20215456
   PubMed Web of Science ®Google Scholar
• Tannus LR Drummond KR Clemente EL da Matta MF Gomes MB Predictors of cardiovascular autonomic neuropathy in patients with type 1 diabetes Front Endocrinol (Lausanne) 2014 5 191 25505446
   PubMed Web of Science ®Google Scholar
• Charles M Fleischer J Witte DR Impact of early detection and treatment of diabetes on the 6-year prevalence of cardiac autonomic neuropathy in people with screen-detected diabetes: ADDITION-Denmark, a cluster-randomised study Diabetologia 2013 56 1 101 108 23064291
   PubMed Web of Science ®Google Scholar
• Abbott CA Chaturvedi N Malik RA Explanations for the lower rates of diabetic neuropathy in Indian Asians versus Europeans Diabetes Care 2010 33 6 1325 1330 20215455
   PubMed Web of Science ®Google Scholar
• Gæde P Oellgaard J Carstensen B Years of life gained by multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: 21 years follow-up on the Steno-2 randomised trial Diabetologia 2016 59 11 2298 2307 27531506
   PubMed Web of Science ®Google Scholar
• Edwards JL Vincent AM Cheng HT Feldman EL Diabetic neuropathy: mechanisms to management Pharmacol Ther 2008 120 1 1 34 18616962
   PubMed Web of Science ®Google Scholar
• Verrotti A Prezioso G Scattoni R Chiarelli F Autonomic neuropathy in diabetes mellitus Front Endocrinol (Lausanne) 2014 5 205 25520703
   PubMed Web of Science ®Google Scholar
• Soriano FG Virág L Szabó C Diabetic endothelial dysfunction: role of reactive oxygen and nitrogen species production and poly(ADP-ribose) polymerase activation J Mol Med 2001 79 8 437 448 11511974
   PubMed Web of Science ®Google Scholar
• Hosseini A Abdollahi M Diabetic neuropathy and oxidative stress: therapeutic perspectives Oxid Med Cell Longev 2013 2013 168039 23738033
   PubMed Web of Science ®Google Scholar
• Adeshara KA Diwan AG Tupe RS Diabetes and complications: cellular signaling pathways, current understanding and targeted therapies Curr Drug Targets 2016 17 11 1309 1328 26648059
   PubMed Web of Science ®Google Scholar
• Vinik AI Erbas T Casellini CM Diabetic cardiac autonomic neuropathy, inflammation and cardiovascular disease J Diabetes Investig 2013 4 1 4 18
   PubMed Web of Science ®Google Scholar
• Polydefkis M Griffin JW McArthur J New insights into diabetic polyneuropathy JAMA 2003 290 10 1371 6 12966130
   PubMed Web of Science ®Google Scholar
• Ziegler D Buchholz S Sohr C Nourooz-Zadeh J Roden M Oxidative stress predicts progression of peripheral and cardiac autonomic nerve dysfunction over 6 years in diabetic patients Acta Diabetol 2015 52 1 65 72 24898524
   PubMed Web of Science ®Google Scholar
• Jaiswal M Fingerlin TE Urbina EM Impact of glycemic control on heart rate variability in youth with type 1 diabetes: the SEARCH CVD study Diabetes Technol Ther 2013 15 12 977 983 24010960
   PubMed Web of Science ®Google Scholar
• Shah MS Brownlee M Molecular and cellular mechanisms of cardiovascular disorders in diabetes Circ Res 2016 118 11 1808 1829 27230643
   PubMed Web of Science ®Google Scholar
• Gibbons C Centi J Vernino S Freeman R Autoimmune autonomic ganglionopathy with reversible cognitive impairment Arch Neurol 2012 69 4 461 466 22158721
   PubMedGoogle Scholar
• Gibbons C Freeman R Antibody titers predict clinical features of autoimmune autonomic ganglionopathy Auton Neurosci 2009 146 1–2 8 12 19144572
   PubMed Web of Science ®Google Scholar
• Skärstrand H Dahlin LB Lernmark A Vaziri-Sani F Neuropeptide Y autoantibodies in patients with long-term type 1 and type 2 diabetes and neuropathy J Diabetes Complications 2013 27 6 609 617 23910631
   PubMed Web of Science ®Google Scholar
• Stroud CR Heller SR Ward JD Hardisty CA Weetman AP Analysis of antibodies against components of the autonomic nervous system in diabetes mellitus QJM 1997 90 9 577 585 9349450
   PubMed Web of Science ®Google Scholar
• Granberg V Ejskjaer N Peakman M Sundkvist G Autoantibodies to autonomic nerves associated with cardiac and peripheral autonomic neuropathy Diabetes Care 2005 28 8 1959 1964 16043739
   PubMed Web of Science ®Google Scholar
• Ejskjaer N Arif S Dodds W Prevalence of autoantibodies to autonomic nervous tissue structures in type 1 diabetes mellitus Diabet Med 1999 16 7 544 549 10445828
   PubMed Web of Science ®Google Scholar
• Berntorp K Frid A Alm R Fredrikson GN Sjöberg K Ohlsson B Antibodies against gonadotropin-releasing hormone (GnRH) in patients with diabetes mellitus is associated with lower body weight and autonomic neuropathy BMC Res Notes 2013 6 329 23958111
   PubMedGoogle Scholar
• Zanone MM Raviolo A Coppo E Association of autoimmunity to autonomic nervous structures with nerve function in patients with type 1 diabetes: a 16-year prospective study Diabetes Care 2014 37 4 1108 1115 24550215
   PubMed Web of Science ®Google Scholar
• Politi C Ciccacci C D’Amato C Novelli G Borgiani P Spallone V Recent advances in exploring the genetic susceptibility to diabetic neuropathy Diabetes Res Clin Pract 2016 120 198 208 27596057
   PubMed Web of Science ®Google Scholar
• Ciccacci C Morganti R Di Fusco D Common polymorphisms in MIR146a, MIR128a and MIR27a genes contribute to neuropathy susceptibility in type 2 diabetes Acta Diabetol 2014 51 4 663 671 24682535
   PubMed Web of Science ®Google Scholar
• Osztovits J Horváth T Littvay L Effects of genetic vs. environmental factors on cardiovascular autonomic function: a twin study Diabet Med 2011 28 10 1241 8 21679234
   PubMed Web of Science ®Google Scholar
• Tahrani AA Obstructive sleep apnoea in diabetes: does it matter? Diab Vasc Dis Res Epub 2017 6 1
   Web of Science ®Google Scholar
• Tahrani AA Ali A Raymond NT Obstructive sleep apnea and diabetic neuropathy: a novel association in patients with type 2 diabetes Am J Respir Crit Care Med 2012 186 5 434 441 22723291
   PubMed Web of Science ®Google Scholar
• Janovsky CC Rolim LC De Sá JR Cardiovascular autonomic neuropathy contributes to sleep apnea in young and lean type 1 diabetes mellitus patients Front Endocrinol (Lausanne) 2014 5 119 25157241
   PubMed Web of Science ®Google Scholar
• Stevens M Ali A Dubb K Begum S Piya M Tahrani A Obstructive sleep apnoea is associated with cardiac autonomic abnormalities in patients with type 2 diabetes Diabet Med 2014 31 37 Available from: https://insights.ovid.com/diabetic-medicine/diame/2014/03/001/obstructive-sleep-apnoea-associated-cardiac/110/00003135 Accessed September 21, 2017
   Web of Science ®Google Scholar
• Altaf Q Ali A Tahrani A The impact of obstructive sleep apnoea on cardiac autonomic neuropathy in patients with type 2 diabetes: a longitudinal study 2017 Available from: http://www.neurodiab2017.com/Portals/0/Docs/abstract_book.pdf Accessed August 31, 2017
   Google Scholar
• Theilade S Lyngbaek S Hansen TW Soluble urokinase plasminogen activator receptor levels are elevated and associated with complications in patients with type 1 diabetes J Intern Med 2015 277 3 362 371 24830873
   PubMed Web of Science ®Google Scholar
• Chung T Prasad K Lloyd TE Peripheral neuropathy: clinical and electrophysiological considerations Neuroimaging Clin N Am 2014 24 1 49 65 24210312
   PubMed Web of Science ®Google Scholar
• Albers JW Pop-Busui R Diabetic neuropathy: mechanisms, emerging treatments, and subtypes Curr Neurol Neurosci Rep 2014 14 8 473 24954624
   PubMed Web of Science ®Google Scholar
• Vinik AI Freeman R Erbas T Diabetic autonomic neuropathy Semin Neurol 2003 23 4 365 372 15088257
   PubMed Web of Science ®Google Scholar
• Pop-Busui R What do we know and we do not know about cardiovascular autonomic neuropathy in diabetes J Cardiovasc Transl Res 2012 5 4 463 478 22644723
   PubMed Web of Science ®Google Scholar
• Hillis G Woodward M Rodgers A Resting heart rate and the risk of death and cardiovascular complications in patients with type 2 diabetes mellitus Diabetologia 2012 55 5 1283 1290 22286552
   PubMed Web of Science ®Google Scholar
• Vinik AI Ziegler D Diabetic cardiovascular autonomic neuropathy Circulation 2007 115 3 387 397 17242296
   PubMed Web of Science ®Google Scholar
• No authors listed Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy Neurology 1996 46 5 1470 8628505
   PubMed Web of Science ®Google Scholar
• Kuehl M Stevens MJ Cardiovascular autonomic neuropathies as complications of diabetes mellitus Nat Rev Endocrinol 2012 8 7 405 416 22371159
   PubMed Web of Science ®Google Scholar
• Ninkovic VM Ninkovic SM Miloradovic V Prevalence and risk factors for prolonged QT interval and QT dispersion in patients with type 2 diabetes Acta Diabetol 2016 53 5 737 744 27107571
   PubMed Web of Science ®Google Scholar
• Veglio M Chinaglia A Cavallo-Perin P QT interval, cardiovascular risk factors and risk of death in diabetes J Endocrinol Invest 2004 27 2 175 181 15129815
   PubMed Web of Science ®Google Scholar
• Sargin H Ozisik M Ozisik NC The prevalence of silent ischemia in Turkish patients with type 2 diabetes mellitus Tohoku J Exp Med 2005 205 4 351 355 15750331
   PubMed Web of Science ®Google Scholar
• Deluca AJ Kaplan S Aronow WS Comparison of prevalence of unrecognized myocardial infarction and of silent myocardial ischemia detected by a treadmill exercise sestamibi stress test in patients with versus without diabetes mellitus Am J Cardiol 2006 98 8 1045 1046 17027568
   PubMed Web of Science ®Google Scholar
• Wackers FJ Young LH Inzucchi SE Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study Diabetes Care 2004 27 8 1954 1961 15277423
   PubMed Web of Science ®Google Scholar
• Deluca AJ Saulle LN Aronow WS Ravipati G Weiss MB Prevalence of silent myocardial ischemia in persons with diabetes mellitus or impaired glucose tolerance and association of hemoglobin A1c with prevalence of silent myocardial ischemia Am J Cardiol 2005 95 12 1472 1474 15950575
   PubMed Web of Science ®Google Scholar
• Ambepityia G Kopelman PG Ingram D Swash M Mills PG Timmis AD Exertional myocardial ischemia in diabetes: a quantitative analysis of anginal perceptual threshold and the influence of autonomic function J Am Coll Cardiol 1990 15 1 72 77 2295745
   PubMed Web of Science ®Google Scholar
• Valensi P Sachs RN Harfouche B Predictive value of cardiac autonomic neuropathy in diabetic patients with or without silent myocardial ischemia Diabetes Care 2001 24 2 339 343 11213889
   PubMed Web of Science ®Google Scholar
• Töyry JP Niskanen LK Länsimies EA Partanen KP Uusitupa MI Autonomic neuropathy predicts the development of stroke in patients with non-insulin-dependent diabetes mellitus Stroke 1996 27 8 1316 1318 8711794
   PubMed Web of Science ®Google Scholar
• Cohen JA Estacio RO Lundgren RA Esler AL Schrier RW Diabetic autonomic neuropathy is associated with an increased incidence of strokes Auton Neurosci 2003 108 1–2 73 78 14614967
   PubMed Web of Science ®Google Scholar
• Ko SH Song KH Park SA Cardiovascular autonomic dysfunction predicts acute ischaemic stroke in patients with type 2 diabetes mellitus: a 7-year follow-up study Diabet Med 2008 25 10 1171 1177 19046195
   PubMed Web of Science ®Google Scholar
• Hayat SA Patel B Khattar RS Malik RA Diabetic cardiomyopathy: mechanisms, diagnosis and treatment Clin Sci 2004 107 6 539 557 15341511
   PubMed Web of Science ®Google Scholar
• Boudina S Abel ED Diabetic cardiomyopathy, causes and effects Rev Endocr Metab Disord 2010 11 1 31 39 20180026
   PubMed Web of Science ®Google Scholar
• Vinik AI Erbas T Diabetic autonomic neuropathy Handb Clin Neurol 2013 117 279 294 24095132
   PubMedGoogle Scholar
• Oakley I Emond L Diabetic cardiac autonomic neuropathy and anesthetic management: review of the literature AANA J 2011 79 6 473 479 22400413
   PubMedGoogle Scholar
• Burgos LG Ebert TJ Asiddao C Increased intraoperative cardiovascular morbidity in diabetics with autonomic neuropathy Anesthesiology 1989 70 4 591 597 2929996
   PubMed Web of Science ®Google Scholar
• Latson TW Ashmore TH Reinhart DJ Klein KW Giesecke AH Autonomic reflex dysfunction in patients presenting for elective surgery is associated with hypotension after anesthesia induction Anesthesiology 1994 80 2 326 337 8311315
   PubMed Web of Science ®Google Scholar
• Yun JS Cha SA Lim TS Cardiovascular autonomic dysfunction predicts diabetic foot ulcers in patients with type 2 diabetes without diabetic polyneuropathy Medicine (Baltimore) 2016 95 12 e3128 27015188
   PubMed Web of Science ®Google Scholar
• Chahal S Vohra K Syngle A Association of sudomotor function with peripheral artery disease in type 2 diabetes Neurol Sci 2017 38 1 151 156 27783183
   PubMed Web of Science ®Google Scholar
• Yun JS Ahn YB Song KH The association between abnormal heart rate variability and new onset of chronic kidney disease in patients with type 2 diabetes: a ten-year follow-up study Diabetes Res Clin Pract 2015 108 1 31 37 25656759
   PubMed Web of Science ®Google Scholar
• Forsén A Kangro M Sterner G A 14-year prospective study of autonomic nerve function in type 1 diabetic patients: association with nephropathy Diabet Med 2004 21 8 852 858 15270788
   PubMed Web of Science ®Google Scholar
• Maser RE Mitchell BD Vinik AI Freeman R The association between cardiovascular autonomic neuropathy and mortality in individuals with diabetes: a meta-analysis Diabetes Care 2003 26 6 1895 1901 12766130
   PubMed Web of Science ®Google Scholar
• Soedamah-Muthu SS Chaturvedi N Witte DR Relationship between risk factors and mortality in type 1 diabetic patients in Europe: the EURODIAB Prospective Complications Study (PCS) Diabetes Care 2008 31 7 1360 1366 18375412
   PubMed Web of Science ®Google Scholar
• Ewing DJ Campbell IW Clarke BF Assessment of cardiovascular effects in diabetic autonomic neuropathy and prognostic implications Ann Intern Med 1980 92 2 Pt 2 308 311 7356219
   PubMed Web of Science ®Google Scholar
• Pafili K Trypsianis G Papzoglou D Maltezos E Papanas N Simplified diagnosis of cardiovascular autonomic neuropathy in type 2 diabetes using Ewing’s battery Rev Diabet Stud 2015 12 1–2 213 219 26676669
   PubMedGoogle Scholar
• Ziegler D Laux G Dannehl K Assessment of cardiovascular autonomic function: age-related normal ranges and reproducibility of spectral analysis, vector analysis, and standard tests of heart rate variation and blood pressure responses Diabet Med 1992 9 2 166 175 1563252
   PubMed Web of Science ®Google Scholar
• Pfeifer MA Cook D Brodsky J Quantitative evaluation of cardiac parasympathetic activity in normal and diabetic man Diabetes 1982 31 4 Pt 1 339 345 7152130
   PubMed Web of Science ®Google Scholar
• Sandroni P Benarroch EE Low PA Pharmacological dissection of components of the Valsalva maneuver in adrenergic failure J Appl Physiol (1985) 1991 71 4 1563 1567 1757382
   PubMed Web of Science ®Google Scholar
• Ewing DJ Campbell IW Murray A Neilson JM Clarke BF Immediate heart-rate response to standing: simple test for autonomic neuropathy in diabetes Br Med J 1978 1 6106 145 147 620228
   PubMed Web of Science ®Google Scholar
• Borowik E Grabowicz W Grycewicz T Lubiński A Clinical usefulness of baroreflex sensitivity test in the detection of cardiovascular autonomic neuropathy in patients with type 2 diabetes mellitus Pol Merkur Lekarski 2015 39 233 277 280 26637091
   PubMedGoogle Scholar
• Zygmunt A Stanczyk J Methods of evaluation of autonomic nervous system function Arch Med Sci 2010 6 1 11 18 22371714
   PubMed Web of Science ®Google Scholar
• Shrivastava S Sukla P Shrivastava P Rao N Assessment of the cardiac autonomic neuropathy among the known diabetics and age-matched controls using noninvasive cardiovascular reflex tests in a south-Indian population: a case-control study Avicenna J Med 2016 6 3 81 85 27390670
   PubMedGoogle Scholar
• Turker Y Aslantas Y Aydin Y Heart rate variability and heart rate recovery in patients with type 1 diabetes mellitus Acta Cardiol 2013 68 2 145 150 23705556
   PubMed Web of Science ®Google Scholar
• Montano N Ruscone TG Porta A Lombardi F Pagani M Malliani A Power spectrum analysis of heart rate variability to assess the changes in sympathovagal balance during graded orthostatic tilt Circulation 1994 90 4 1826 1831 7923668
   PubMed Web of Science ®Google Scholar
• La Rovere M Maestri R Pinna G Baroreflex sensitivity assessment: latest advances and strategies Eur Cardiol 2011 7 2 89 92
   Google Scholar
• Kamińska A Tafil-Klawe M Smietanowski M Spontaneous baroreflex sensitivity in subjects with type 1 diabetes with and without cardiovascular autonomic neuropathy Endokrynol Pol 2008 59 5 398 402 18979450
   PubMedGoogle Scholar
• Svačinová J Honzíková N Krtička A Tonhajzerová I Javorka K Javorka M Diagnostic significance of a mild decrease of baroreflex sensitivity with respect to heart rate in type 1 diabetes mellitus Physiol Res 2013 62 6 605 613 23869895
   PubMed Web of Science ®Google Scholar
• Messmer EM Schmid-Tannwald C Zapp D Kampik A In vivo confocal microscopy of corneal small fiber damage in diabetes mellitus Graefes Arch Clin Exp Ophthalmol 2010 248 9 1307 1312 20490534
   PubMed Web of Science ®Google Scholar
• Tavakoli M Begum P McLaughlin J Malik R Corneal confocal microscopy for the diagnosis of diabetic autonomic neuropathy Muscle Nerve 2015 52 3 363 370 25556884
   PubMed Web of Science ®Google Scholar
• Maddaloni E Sabatino F Del Toro R In vivo corneal confocal microscopy as a novel non-invasive tool to investigate cardiac autonomic neuropathy in type 1 diabetes Diabet Med 2014 32 2 262 266 25251450
   PubMed Web of Science ®Google Scholar
• Buse JB Ginsberg HN Bakris GL Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes Association Circulation 2007 115 1 114 126 17192512
   PubMed Web of Science ®Google Scholar
• Howorka K Pumprla J Haber P Koller-Strametz J Mondrzyk J Schabmann A Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy Cardiovasc Res 1997 34 1 206 214 9217892
   PubMed Web of Science ®Google Scholar
• Soares-Miranda L Sandercock G Vale S Metabolic syndrome, physical activity and cardiac autonomic function Diabetes Metab Res Rev 2012 28 4 363 369 22238216
   PubMed Web of Science ®Google Scholar
• Motooka M Koike H Yokoyama T Kennedy NL Effect of dog-walking on autonomic nervous activity in senior citizens Med J Aust 2006 184 2 60 63 16411869
   PubMed Web of Science ®Google Scholar
• Carnethon MR Prineas RJ Temprosa M The association among autonomic nervous system function, incident diabetes, and intervention arm in the Diabetes Prevention Program Diabetes Care 2006 29 4 914 919 16567837
   PubMed Web of Science ®Google Scholar
• Voulgari C Pagoni S Vinik A Poirier P Exercise improves cardiac autonomic function in obesity and diabetes Metab Clin Exp 2013 62 5 609 621 23084034
   PubMed Web of Science ®Google Scholar
• Esposito P Mereu R De Barbieri G Trained breathing-induced oxygenation acutely reverses cardiovascular autonomic dysfunction in patients with type 2 diabetes and renal disease Acta Diabetol 2016 53 2 217 226 25956276
   PubMed Web of Science ®Google Scholar
• Ceriello A Esposito K Ihnat M Thorpe J Giugliano D Long-term glycemic control influences the long-lasting effect of hyperglycemia on endothelial function in type 1 diabetes J Clin Endocrinol Metab 2009 94 8 2751 2756 19491221
   PubMed Web of Science ®Google Scholar
• Jaiswal M Urbina EM Wadwa RP Reduced heart rate variability among youth with type 1 diabetes: the SEARCH CVD study Diabetes Care 2013 36 1 157 162 22961570
   PubMed Web of Science ®Google Scholar
• Azad N Emanuele NV Abraira C The effects of intensive glycemic control on neuropathy in the VA cooperative study on type II diabetes mellitus (VA CSDM) J Diabetes Complications 1999 13 5–6 307 313 10765007
   PubMed Web of Science ®Google Scholar
• Gæde P Vedel P Parving HH Pedersen O Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study Lancet 1999 353 9153 617 622 10030326
   PubMed Web of Science ®Google Scholar
• Ziegler D Schatz H Conrad F Gries FA Ulrich H Reichel G Effects of treatment with the antioxidant α-lipoic acid on cardiac autonomic neuropathy in NIDDM patients: a 4-month randomized controlled multicenter trial (DEKAN study). Deutsche Kardiale Autonome Neuropathie Diabetes Care 1997 20 3 369 73 9051389
   PubMed Web of Science ®Google Scholar
• Manzella D Barbieri M Ragno E Paolisso G Chronic administration of pharmacologic doses of vitamin E improves the cardiac autonomic nervous system in patients with type 2 diabetes Am J Clin Nutr 2001 73 6 1052 1057 11382659
   PubMed Web of Science ®Google Scholar
• Pop-Busui R Stevens MJ Raffel DM Effects of triple antioxidant therapy on measures of cardiovascular autonomic neuropathy and on myocardial blood flow in type 1 diabetes: a randomised controlled trial Diabetologia 2013 56 8 1835 1844 23740194
   PubMed Web of Science ®Google Scholar
• Johansson BL Borg K Fernqvist-Forbes E Kernell A Odergren T Wahren J Beneficial effects of C-peptide on incipient nephropathy and neuropathy in patients with type 1 diabetes mellitus Diabet Med 2000 17 3 181 189 10784221
   PubMed Web of Science ®Google Scholar
• Hu X Li S Yang G Liu H Boden G Li L Efficacy and safety of aldose reductase inhibitor for the treatment of diabetic cardiovascular autonomic neuropathy: systematic review and meta-analysis PLoS One 2014 9 2 e87096 24533052
   PubMed Web of Science ®Google Scholar
• Johnson BF Nesto RW Pfeifer MA Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administration Diabetes Care 2004 27 2 448 454 14747227
   PubMed Web of Science ®Google Scholar
• Athyros VG Didangelos TP Karamitsos DT Papageorgiou AA Boudoulas H Kontopoulos AG Long-term effect of converting enzyme inhibition on circadian sympathetic and parasympathetic modulation in patients with diabetic autonomic neuropathy Acta Cardiol 1998 53 4 201 209 9842405
   PubMed Web of Science ®Google Scholar
• Ziegler D Low PA Freeman R Tritschler H Vinik AI Predictors of improvement and progression of diabetic polyneuropathy following treatment with α-lipoic acid for 4 years in the NATHAN 1 trial J Diabetes Complications 2016 30 2 350 356 26651260
   PubMed Web of Science ®Google Scholar
• Baruch L Anand I Cohen IS Ziesche S Judd D Cohn JN Augmented short- and long-term hemodynamic and hormonal effects of an angiotensin receptor blocker added to angiotensin converting enzyme inhibitor therapy in patients with heart failure Circulation 1999 99 20 2658 2664 10338459
   PubMed Web of Science ®Google Scholar
• Ebbehøj E Poulsen PL Hansen KW Knudsen ST Mølgaard H Mogensen CE Effects on heart rate variability of metoprolol supplementary to ongoing ACE-inhibitor treatment in type I diabetic patients with abnormal albuminuria Diabetologia 2002 45 7 965 975 12136395
   PubMed Web of Science ®Google Scholar
• Lampert R Ickovics JR Viscoli CJ Horwitz RI Lee FA Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial Am J Cardiol 2003 91 2 137 142 12521623
   PubMed Web of Science ®Google Scholar
• Shibao C Lipsitz LA Biaggioni I ASH position paper: evaluation and treatment of orthostatic hypotension J Clin Hypertens (Greenwich) 2013 15 3 147 153 23458585
   PubMed Web of Science ®Google Scholar