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Perspectives

Reexploring 5-methoxyindole-2-carboxylic acid (MICA) as a potential antidiabetic agent

Pages 183-186 | Published online: 04 May 2018

References

  • Barnett AH Type 2 Diabetes 2nd ed Oxford, UK Oxford University Press 2012
  • Yan LJ Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress J Diabetes Res 2014 2014 137919 25019091
  • Luo X Wu J Jing S Yan LJ Hyperglycemic stress and carbon stress in diabetic glucotoxicity Aging Dis 2016 7 1 90 110 26816666
  • Wu J Jin Z Yang X Yan LJ Post-ischemic administration of 5-methoxyindole-2-carboxylic acid at the onset of reperfusion affords neuroprotection against stroke injury by preserving mitochondrial function and attenuating oxidative stress Biochem Biophys Res Commun 2018 497 1 444 450 29448100
  • Wu J Li R Li W Administration of 5-methoxyindole-2-carboxylic acid that potentially targets mitochondrial dihydrolipoamide dehydrogenase confers cerebral preconditioning against ischemic stroke injury Free Radic Biol Med 2017 113 244 254 29017857
  • Karnell R von Schoultz E Hansson LO Nilsson B Arstrand K Kagedal B S100B protein, 5-S-cysteinyldopa and 6-hydroxy-5-methoxyindole-2-carboxylic acid as biochemical markers for survival prognosis in patients with malignant melanoma Melanoma Res 1997 7 5 393 399 9429222
  • Hanson RL Ray PD Walter P Lardy HA Mode of action of hypoglycemic agents. I. Inhibition of gluconeogenesis by quinaldic acid and 5-methoxyindole-2-carboxylic acid J Biol Chem 1969 244 16 4351 4359 5806581
  • Reed J Lardy HA Mode of action of hypoglycemic agents. 3. Studies on 5-methoxy indole-2-carboxylic acid and quinaldic acid J Biol Chem 1970 245 20 5297 5303 5469167
  • Li YY Wu HS Tang L The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo Pharmacol Res 2007 56 4 335 343 17889553
  • Sharma V Kumar P Pathak D Biological importance of the indole nucleus in recent years: a comprehensive review J Heterocycl Chem 2010 47 491 502
  • Daligcon BC Oyama J Hannak K Increased gluconeogenesis in rats exposed to hyper-G stress Life Sci 1985 37 3 235 241 4010477
  • Garcia-Salguero L Aranda F Peragon J Corpas FJ Lupianez JA Metabolic adaptation of renal carbohydrate metabolism. IV. The use of site-specific liver gluconeogenesis inhibitors to ascertain the role of renal gluconeogenesis Arch Int Physiol Biochim Biophys 1991 99 3 237 242 1717058
  • Bauman N Pease BS Effects of 5-methoxyindole-2-carboxylic acid on carbohydrate metabolism Biochem Pharmacol 1969 18 5 1093 1101 5789776
  • Bauman N Hill CJ Inhibition of gluconeogenesis and α-keto oxidation by 5-methoxyindole-2-carboxylic acid Biochemistry 1968 7 4 1322 1327 4878041
  • Haramaki N Han D Handelman GJ Tritschler HJ Packer L Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of α-lipoic acid Free Radic Biol Med 1997 22 3 535 542 8981046
  • Miller JA Runkle SA Tjalkens RB Philbert MA 1,3-Dinitrobenzene induced metabolic impairment through selective inactivation of the pyruvate dehydrogenase complex Toxicol Sci 2011 122 2 502 511 21551353
  • Williams CHJr Lipoamide dehydrogenase, glutathione reductase, thioredoxin reductase, and mercuric ion reductase-a family of flavoenzyme transhydrogenases Muller F Chemistry and Biochemistry of Flavoenzymes III Boca Raton, FL, USA CRC Press 1992 121 212
  • Yan LJ Yang SH Shu H Prokai L Forster MJ Histochemical staining and quantification of dihydrolipoamide dehydrogenase diaphorase activity using blue native PAGE Electrophoresis 2007 28 7 1036 1045 17315258
  • Gorin E Zendowski S Effect of methoxyindole 2-carboxylic acid and 4-pentenoic acid on adipose tissue metabolism Biochim Biophys Acta 1975 388 2 268 278 1138899
  • Siva AB Panneerdoss S Sailasree P Singh DK Kameshwari DB Shivaji S Inhibiting sperm pyruvate dehydrogenase complex and its E3 subunit, dihydrolipoamide dehydrogenase affects fertilization in Syrian hamsters PLoS One 2014 9 5 e97916 24852961
  • Andrzejewski S Gravel SP Pollak M St-Pierre J Metformin directly acts on mitochondria to alter cellular bioenergetics Cancer Metab 2014 2 12 25184038
  • Schillinger E Loge O Metabolic effects and mortality rate in diabetic Chinese hamsters after long-term treatment with 5-methoxyindole-2-carboxylic acid (MICA) Arzneimittelforschung 1976 26 4 554 556 989012
  • Kumar V Kota V Shivaji S Hamster sperm capacitation: role of pyruvate dehydrogenase A and dihydrolipoamide dehydrogenase Biol Reprod 2008 79 2 190 199 18401010
  • Yan LJ Thangthaeng N Sumien N Forster MJ Serum dihydrolipoamide dehydrogenase is a labile enzyme J Biochem Pharmacol Res 2013 1 1 30 42 23646291
  • Richarme G el Yaagoubi A Kohiyama M The MglA component of the binding protein-dependent galactose transport system of Salmonella typhimurium is a galactose-stimulated ATPase J Biol Chem 1993 268 13 9473 9477 8387496
  • Sun Z Park SY Hwang E Thymus vulgaris alleviates UVB irradiation induced skin damage via inhibition of MAPK/AP-1 and activation of Nrf2-ARE antioxidant system J Cell Mol Med 2017 21 2 336 348 27641753
  • Aomine M Effects of 5-methoxyindole-2-carboxylic acid on growth, glucose uptake and glycogen content in Tetrahymena pyriformis GL Int J Biochem 1977 8 1 27 32
  • Kerscher L Oesterhelt D Pyruvate: ferredoxin oxidoreductase – new findings on an ancient enzyme Trends Biochem Sci 1982 7 10 371 374
  • Meury J 5-Methoxyindole-2-carboxylic acid is a potent inhibitor of respiration and potassium ion transport in the archaebacterium Haloferax volcanni FEMS Micobiol Lett 1993 108 3 271 274
  • Heefner DL Currie MG Rossi RF Zepp CM inventors Sepracor Inc., assignee D-amino acid oxidase inhibitors for learning and memory United States patent US 20030162825A1 2003