References
- Whiting DR Guariguata L Weil C Shaw J IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030 Diabetes Res Clin Pract 2011 94 3 311 321 22079683
- Copeland KC Silverstein J Moore KR Management of newly diagnosed type 2 Diabetes Mellitus (T2DM) in children and adolescents Pediatrics 2013 131 2 364 382 23359574
- Ciulla TA Amador AG Zinman B Diabetic retinopathy and diabetic macular edema: pathophysiology, screening, and novel therapies Diabetes Care 2003 26 9 2653 2664 12941734
- Stratton IM Adler AI Neil HA Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study BMJ 2000 321 7258 405 412 10938048
- Davidson MH Hauptman J DiGirolamo M Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial JAMA 1999 281 3 235 242 9918478
- Lavie CJ Milani RV Ventura HO Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss J Am Coll Cardiol 2009 53 21 1925 1932 19460605
- Eckel RH Kahn SE Ferrannini E Obesity and type 2 diabetes: what can be unified and what needs to be individualized? J Clin Endocrinol Metab 2011 96 6 1654 1663 21602457
- Kim SH Reaven G Obesity and insulin resistance: an ongoing saga Diabetes 2010 59 9 2105 2106 20805385
- Xi P Liu RH Whole food approach for type 2 diabetes prevention Mol Nutr Food Res 2016 60 8 1819 1836 27159643
- Hausenblas HA Schoulda JA Smoliga JM Resveratrol treatment as an adjunct to pharmacological management in type 2 diabetes mellitus--systematic review and meta-analysis Mol Nutr Food Res 2015 59 1 147 159 25138371
- Huang H Chen G Dong Y Zhu Y Chen H Chromium supplementation for adjuvant treatment of type 2 diabetes mellitus: results from a pooled analysis Mol Nutr Food Res 2018 62 1 1700438
- Lamson DW Plaza SM Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment Altern Med Rev 2002 7 2 94 111 11991790
- Joseph AM Joanisse DR Baillot RG Hood DA Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions Exp Diabetes Res 2012 2012 642038 22203837
- Garrido-Maraver J Cordero MD Oropesa-Avila M Clinical applications of coenzyme Q10 Front Biosci (Landmark Ed) 2014 19 4 619 633 24389208
- Hernández-Camacho JD Bernier M López-Lluch G Navas P Coenzyme Q10 supplementation in aging and disease Front Physiol 2018 9 44 29459830
- Hargreaves IP Coenzyme Q10 as a therapy for mitochondrial disease Int J Biochem Cell Biol 2014 49 105 111 24495877
- Ates O Bilen H Keles S Plasma coenzyme Q10 levels in type 2 diabetic patients with retinopathy Int J Ophthalmol 2013 6 5 675 679 24195048
- Hasegawa G Yamamoto Y Zhi JG Daily profile of plasma %CoQ10 level, a biomarker of oxidative stress, in patients with diabetes manifesting postprandial hyperglycaemia Acta Diabetol 2005 42 4 179 181 16382305
- Mezawa M Takemoto M Onishi S The reduced form of coenzyme Q10 improves glycemic control in patients with type 2 diabetes: an open label pilot study Biofactors 2012 38 6 416 421 22887051
- Kadhim Mohammed-Jawad N Al- Sabbagh M Al-Jezaeri KA Role of L-carnitine and coenzyme Q10 as adjuvant therapy in patients with type 2 diabetes mellitus Am J Pharmacol Sci 2014 2 5 82 86
- Moazen M Mazloom Z Ahmadi A Dabbaghmanesh MH Roosta S Effect of coenzyme Q10 on glycaemic control, oxidative stress and adiponectin in type 2 diabetes J Pak Med Assoc 2015 65 4 404 408 25976576
- Mehrdadi P Kolahdouz Mohammadi R Alipoor E Eshraghian MR Esteghamati A Hosseinzadeh-Attar MJ The effect of coenzyme Q10 supplementation on circulating levels of novel adipokine Adipolin/CTRP12 in overweight and obese patients with type 2 diabetes Exp Clin Endocrinol Diabetes 2017 125 3 156 162 27657997
- Eriksson JG Forsén TJ Mortensen SA Rohde M The effect of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus Biofactors 1999 9 2–4 315 318 10416046
- Zahedi H Eghtesadi S Seifirad S Effects of CoQ10 supplementation on lipid profiles and glycemic control in patients with type 2 diabetes: a randomized, double blind, placebo-controlled trial J Diabetes Metab Disord 2014 13 81 26413493
- Liberati A Altman DG Tetzlaff J The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration PLoS Med 2009 6 7 e1000100 19621070
- Higgins JP Green S homepage on the Internet Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] Available from: http://handbook.cochrane.org/ Accessed October 26, 2018
- Guyatt GH Oxman AD Vist GE GRADE Working Group GRADE: an emerging consensus on rating quality of evidence and strength of recommendations BMJ 2008 336 7650 924 926 18436948
- Higgins JP Thompson SG Deeks JJ Altman DG Measuring inconsistency in meta-analyses BMJ 2003 327 7414 557 560 12958120
- Egger M Davey Smith G Schneider M Minder C Bias in meta-analysis detected by a simple, graphical test BMJ 1997 315 7109 629 634 9310563
- Morton SC Adams JL Suttorp MJ Shekelle PG Meta-regression Approaches: What, Why, When, and How? Rockville, MD USA Agency for Healthcare Research and Quality 2004
- Chew GT Watts GF Davis TM Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction Diabetes Care 2008 31 8 1502 1509 18487480
- Hamilton SJ Chew GT Watts GF Coenzyme Q10 improves endothelial dysfunction in statin-treated type 2 diabetic patients Diabetes Care 2009 32 5 810 812 19228872
- Hernández-Ojeda J Cardona-Muñoz EG Román-Pintos LM The effect of ubiquinone in diabetic polyneuropathy: a randomized double-blind placebo-controlled study J Diabetes Complications 2012 26 4 352 358 22595020
- Hosseinzadeh-Attar M Kolahdouz Mohammadi R Eshraghian M Reduction in asymmetric dimethylarginine plasma levels by coenzyme Q10 supplementation in patients with type 2 diabetes mellitus Minerva Endocrinol 2015 40 4 259 266 26140473
- Lim SC Lekshminarayanan R Goh SK The effect of coenzyme Q10 on microcirculatory endothelial function of subjects with type 2 diabetes mellitus Atherosclerosis 2008 196 2 966 969 18164307
- Playford DA Watts GF Croft KD Burke V Combined effect of coenzyme Q10 and fenofibrate on forearm microcirculatory function in type 2 diabetes Atherosclerosis 2003 168 1 169 179 12732401
- Raygan F Rezavandi Z Dadkhah Tehrani S Farrokhian A Asemi Z The effects of coenzyme Q10 administration on glucose homeostasis parameters, lipid profiles, biomarkers of inflammation and oxidative stress in patients with metabolic syndrome Eur J Nutr 2016 55 8 2357 2364 26385228
- Gholami M Rezvanfar MR Delavar M Abdollahi M Khosrowbeygi A Effects of coenzyme Q10 supplementation on serum values of gamma-glutamyl transferase, pseudocholinesterase, bilirubin, ferritin, and high-sensitivity c-reactive protein in women with type 2 diabetes Exp Clin Endocrinol Diabetes 2018
- Akbari Fakhrabadi M Zeinali Ghotrom A Mozaffari-Khosravi H Hadi Nodoushan H Nadjarzadeh A Effect of coenzyme Q10 on oxidative stress, glycemic control and inflammation in diabetic neuropathy: a double blind randomized clinical trial Int J Vitam Nutr Res 2014 84 5–6 252 260 26255546
- Moradi M Haghighatdoost F Feizi A Larijani B Azadbakht L Effect of coenzyme Q10 supplementation on diabetes biomarkers: a systematic review and meta-analysis of randomized controlled clinical trials Arch Iran Med 2016 19 8 588 596 27544369
- Suksomboon N Poolsup N Juanak N Effects of coenzyme Q10 supplementation on metabolic profile in diabetes: a systematic review and meta-analysis J Clin Pharm Ther 2015 40 4 413 418 25913756
- Ceriello A Oxidative stress and glycemic regulation Metabolism 2000 49 2 Suppl 1 27 29 10693917
- Keane KN Cruzat VF Carlessi R de Bittencourt PI Newsholme P Molecular events linking oxidative stress and inflammation to insulin resistance and β-cell dysfunction Oxid Med Cell Longev 2015 2015 181643 26257839
- Amin MM Asaad GF Abdel Salam RM El-Abhar HS Arbid MS Novel CoQ10 antidiabetic mechanisms underlie its positive effect: modulation of insulin and adiponectine receptors, tyrosine kinase, PI3K, glucose transporters, sRAGE and visfatin in insulin resistant/diabetic rats PLoS One 2014 9 2 e89169 24586567
- Lee SK Lee JO Kim JH Coenzyme Q10 increases the fatty acid oxidation through AMPK-mediated PPARα induction in 3T3-L1 preadipocytes Cell Signal 2012 24 12 2329 2336 22885103
- Skoglund-Andersson C Karpe F Hellénius ML Regnström J Hamsten A Tornvall P In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins Eur J Clin Invest 2003 33 1 51 57 12492452
- Singh RB Niaz MA Rastogi SS Shukla PK Thakur AS Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease J Hum Hypertens 1999 13 3 203 208 10204818
- Digiesi V Cantini F Oradei A Coenzyme Q10 in essential hypertension Mol Aspects Med 1994 15 Suppl s257 s263 7752838
- Pepe S Marasco SF Haas SJ Sheeran FL Krum H Rosenfeldt FL Coenzyme Q10 in cardiovascular disease Mitochondrion 2007 7 Suppl S154 S167 17485243
- Lönnrot K Pörsti I Alho H Wu X Hervonen A Tolvanen JP Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats Br J Pharmacol 1998 124 7 1500 1506 9723964
- Hidaka T Fujii K Funahashi I Fukutomi N Hosoe K Safety assessment of coenzyme Q10 (CoQ10) Biofactors 2008 32 1–4 199 208 19096117
- Haas AV McDonnell ME Pathogenesis of cardiovascular disease in diabetes Endocrinol Metab Clin North Am 2018 47 1 51 63 29407056
- Carr ME Diabetes mellitus: a hypercoagulable state J Diabetes Complications 2001 15 1 44 54 11259926
- Watson KE Peters Harmel AL Matson G Atherosclerosis in type 2 diabetes mellitus: the role of insulin resistance J Cardiovasc Pharmacol Ther 2003 8 4 253 260 14740074