126
Views
3
CrossRef citations to date
0
Altmetric
Original Research

Association of Metabolic Obesity Phenotypes and Total Testosterone in Chinese Male Population

, , , , , , , , & show all
Pages 399-408 | Published online: 29 Jan 2021

References

  • Pinkey JH , Kopelman PG . Endocrine Determinant of Obesity. In: Bray GA, Bouchard C, Handbook of Obesity. Etiology and Pathophysiology . 2nd ed ed. New York: Marcel Dekker; 2004:655–670.
  • Kalyani RR , Dobs AS . Androgen deficiency, diabetes, and the metabolic syndrome in men. Curr Opin Endocrinol Diabetes Obes . 2007;14(3):226–234. doi:10.1097/MED.0b013e32814db856 17940444
  • Escobar-Morreale HF , Santacruz E , Luque-Ramírez M , Botella Carretero JI . Prevalence of ‘obesity-associated gonadal dysfunction’ in severely obese men and women and its resolution after bariatric surgery: a systematic review and meta-analysis. Hum Reprod Update . 2017;1–19.
  • Pasquali R , Vicennati V , Gambineri A . Adrenal and gonadal function in obesity. J Endocrinol Invest . 2002;25:893–898. doi:10.1007/BF03344053 12508952
  • Eriksson J , Haring R , Grarup N , et al. Causal relationship between obesity and serum testosterone status in men: a bi-directional mendelian randomization analysis. PLoS One . 2017;12(4):4. doi:10.1371/journal.pone.0176277
  • Renato Pasquali R . Obesity and androgens: facts and perspectives. Fertil Steril . 2006;85(5):1319–1340. doi:10.1016/j.fertnstert.2005.10.054 16647374
  • Munoz-Garach A , Cornejo-Pareja I , Tinahones FJ . Does metabolically healthy obesity exist? Nutrients . 2016;8(6):320. doi:10.3390/nu8060320
  • Brand JS , Rovers MM , Yeap BB , et al. Testosterone, sex hormone-binding globulin and the metabolic syndrome in men: an individual participant data meta-analysis of observational studies. PLoS One . 2014;9(7):e100409. doi:10.1371/journal.pone.0100409 25019163
  • Corona G , Monami M , Rastrelli G , et al. Testosterone and metabolic syndrome: a meta-analysis study. J Sex Med . 2011;8(1):272–283. doi:10.1111/j.1743-6109.2010.01991.x 20807333
  • Angelova P , Kamenov Z , Tsakova A , El-Darawish Y , Okamura H . Interleukin-18 and testosterone levels in men with metabolic syndrome.. Aging Male . 2018;21(2):130–137. doi:10.1080/13685538.2017.1401993 29168426
  • Hong D , Kim Y-S , Son ES , et al. Total testosterone and sex hormone-binding globulin are associated with metabolic syndrome independent of age and body mass index in Korean men. Maturitas . 2013;74:148–153. doi:10.1016/j.maturitas.2012.10.016 23218685
  • Sá EQ , Sá FC , Oliveira KC , Feres F , Verreschi IT . Association between sex hormone-binding globulin (SHBG) and metabolic syndrome among men. Sao Paulo Med J . 2014;132(2):111–115. doi:10.1590/1516-3180.2014.1322666 24714992
  • Zhang J , Huang X , Liao M , et al. Both total testosterone and sex hormone-binding globulin are independent risk factors for metabolic syndrome: results from fangchenggang area male health and examination survey in China. Diabetes Metab Res Rev . 2013;29:391–397. doi:10.1002/dmrr.2405 23463406
  • Siddiqui K , Al-Rubeaan K , Nawaz SS , Aburisheh KH , Alaabdin AMZ , Tolba IA . Serum Sex Hormone Binding Globulin (SHBG) relation with different components of metabolic syndrome in men with type 2 diabetes. Horm Metab Res . 2018;50(2):138–144. doi:10.1055/s-0043-123348 29245159
  • Callou de Sá EQ , Feijó de Sá FC , e Silva RDS , et al. Endogenous oestradiol but not testosterone is related to coronary artery disease in men. Clin Endocrinol (Oxf) . 2011;75(2):177–183. doi:10.1111/j.1365-2265.2011.04017.x 21521286
  • Bhasin S , Jasjua GK , Pencina M , et al. Sex hormone-binding globulin, but not testosterone, is associated prospectively and independently with incident metabolic syndrome in men: the framingham heart study. Diabetes Care . 2011;34(11):2464–2470. doi:10.2337/dc11-0888 21926281
  • Lopez-Miranda J , Perez-Martinez P . It is time to define metabolically obese but normal-weight (MONW) individuals. Clin Endocrinol (Oxf) . 2013;79(3):314–315. doi:10.1111/cen.12181 23445212
  • Martini AC , Molina RI , Ruiz RD , Fiol de Cuneo M . Obesity and male fertility. Rev Fac Cien Med Univ Nac Cordoba . 2012;69:2.
  • Lotti F , Rastrelli G , Maseroli E , et al. Impact of metabolically healthy obesity in patients with andrological problems. J Sex Med . 2019;16(6):821–832. doi:10.1016/j.jsxm.2019.03.006 30962157
  • Wang C , Nieschlag E , Swerdloff R , et al. Investigation, treatment, and monitoring of late-onset hypogonadism in males: ISA, ISSAM, EAU, EAA, and ASA recommendations. J Androl . 2008;30(1):1–9. doi:10.2164/jandrol.108.006486 18772485
  • Lauer MS, Fontanarosa PB. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III). JAMA . 2001;285(19):2486–2497. doi:10.1001/jama.285.19.2486 11368702
  • Kim JM , Kim BH , Lee H , et al. The relationship between thyroid function and different obesity phenotypes in Korean euthyroid adults. Diabetes Metab J . 2019;43(6):867–878.30968620
  • Pitteloud N , Hardin M , Dwyer AA , et al. Increasing insulin resistance is associated with a decrease in leydig cell testosterone secretion in men. J Clin Endocrinol Metab . 2005;90:2636–2641. doi:10.1210/jc.2004-2190 15713702
  • Lin T , Wang D , Stocco DM . Interleukin-1 inhibits leydig cell steroidogenesis without affecting steroidogenic acute regulatory protein messenger ribonucleic acid or protein levels. J Endocrinol . 1998;156:461–467. doi:10.1677/joe.0.1560461 9582502
  • Primeau V , Coderre L , Karelis AD , et al. Characterizing the profile of obese patients who are metabolic healthy. Int I Obes (Lond) . 2011;35:971–981. doi:10.1038/ijo.2010.216
  • Wang B , Zhang M , Wang S , et al. Dynamic status of metabolically healthy overweight/obesity and metabolically unhealthy and normal weight and the risk of type 2 diabetes mellitus: a cohort study of a rural adult Chinese population. Obes Res Clin Pract . 2018;12(1):61–71. doi:10.1016/j.orcp.2017.10.005 29100915
  • Ortega FB , Cadenas-Sanchez C , Migueles JH , et al. Role of physical activity and fitness in the characterization and prognosis of the metabolically healthy obesity phenotype: a systematic review and meta-analysis. Prog Cardiovasc Dis . 2018;61(2):190–205. doi:10.1016/j.pcad.2018.07.008 30122522
  • Yeh T-L , Chen -H-H , Tsai S-Y , Lin C-Y , Liu S-J , Chien K-L . The relationship between metabolically healthy obesity and the risk of cardiovascular disease: a systematic review and meta-analysis. J Clin Med . 2019;8(8):1228. doi:10.3390/jcm8081228
  • Perez-Martinez P , Alcala-Diaz JF , Delgado-Lista J , et al. Metabolic phenotypes of obesity influence triglyceride and inflammation homoeostasis. Eur J Clin Invest . 2014;44(11):1053–1064. doi:10.1111/eci.12339 25231836
  • Wildman RP , Muntner P , Reynolds K , et al. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999–2004). Arch Intern Med . 2008;168:1617–1624. doi:10.1001/archinte.168.15.1617 18695075
  • Karelis AD , St-Pierre DH , Conus F , Rabasa-Lhoret R , Poehlman ET . Metabolic and body composition factors in subgroups of obesity: what do we know? J Clin Endocrinol Metab . 2004;89(6):2569e75. doi:10.1210/jc.2004-0165 15181025
  • Yoo HJ , Hwang SY , Hong HC , et al. Association of metabolically abnormal but normal weight (MANW) and metabolically healthy but obese (MHO) individuals with arterial stiffness and carotid atherosclerosis. Atherosclerosis . 2014;234(1):218–223. doi:10.1016/j.atherosclerosis.2014.02.033 24681911
  • Choi KM , Cho HJ , Choi HY , et al. Higher mortality in metabolically obese normal-weight people than in metabolically healthy obese subjects in elderly Koreans. Clin Endocrinol (Oxf) . 2013;79(3):364–370. doi:10.1111/cen.12154 23330616
  • Kim M , Paik JK , Kim KR , et al. Increased oxidative stress in normal-weight postmenopausal women with metabolic syndrome compared with metabolically healthy overweight/obese individuals. Metabolism . 2012;62(4):554–560. doi:10.1016/j.metabol.2012.10.006 23142163
  • Vermeulen A , Kaufman JM , Deslypere JP , Thomas G . Attenuated luteinizing hormone (LH) pulse amplitude but normal LH pulse frequency, and its relation to plasma androgens in hypogonadism of obese men. J Clin Endocrinol Metab . 1993;76(5):1140–1146. doi:10.1210/jcem.76.5.8496304 8496304
  • George JT , Millar RP , Anderson RA . Hypothesis: kisspeptin mediates male hypogonadism in obesity and type 2 diabetes. Neuroendocrinology . 2010;91(4):302–307. doi:10.1159/000299767 20628262