Assessing MicroRNA-375 Levels in Type 2 Diabetes Mellitus (T2DM) Patients and Their First-Degree Relatives with T2DM

References

• O’Brien J , Hayder H , Zayed Y , Peng C . Overview of MicroRNA biogenesis, mechanisms of actions, and circulation. Front Endocrinol (Lausanne) . 2018;9:402. doi:10.3389/fendo.2018.00402 30123182
   PubMed Web of Science ®Google Scholar
• Asahara H . Current status and strategy of microRNA research for cartilage development and osteoarthritis pathogenesis. J Bone Metab . 2016;23(3):121–127. doi:10.11005/jbm.2016.23.3.121 27622175
   PubMedGoogle Scholar
• Kim VN , Han J , Siomi MC . Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol . 2009;10(2):126–139. doi:10.1038/nrm2632 19165215
   PubMed Web of Science ®Google Scholar
• Zhu H , Fan G-C . Extracellular/circulating microRNAs and their potential role in cardiovascular disease. Am J Cardiovasc Dis . 2011;1(2):138–149.22059153
   PubMedGoogle Scholar
• Fransquet PD , Ryan J . Micro RNA as a potential blood-based epigenetic biomarker for alzheimer’s disease. Clin Biochem . 2018;58:5–14. doi:10.1016/j.clinbiochem.2018.05.020 29885309
   PubMed Web of Science ®Google Scholar
• Gilad S , Meiri E , Yogev Y , et al. Serum microRNAs are promising novel biomarkers. PLoS One . 2008;3(9):e3148. doi:10.1371/journal.pone.0003148 18773077
   PubMed Web of Science ®Google Scholar
• Seyhan AA . microRNAs with different functions and roles in disease development and as potential biomarkers of diabetes: progress and challenges. Mol Biosyst . 2015;11(5):1217–1234. doi:10.1039/c5mb00064e 25765998
   PubMedGoogle Scholar
• Wang Q , Huang Z , Ni S , et al. Plasma miR-601 and miR-760 are novel biomarkers for the early detection of colorectal cancer. PLoS One . 2012;7(9):e44398. doi:10.1371/journal.pone.0044398 22970209
   PubMed Web of Science ®Google Scholar
• Wojciechowska A , Braniewska A , Kozar-Kamińska K . MicroRNA in cardiovascular biology and disease. Adv Clin Exp Med . 2017;26(5):865–874. doi:10.17219/acem/62915 29068585
   PubMed Web of Science ®Google Scholar
• Tang X , Tang G , Ozcan S . Role of microRNAs in diabetes. Biochim Biophys Acta . 2008;1779(11):697–701. doi:10.1016/j.bbagrm.2008.06.010 18655850
   PubMed Web of Science ®Google Scholar
• Alharbi KK , Abudawood M , Ali Khan I . Amino-acid amendment of arginine-325-tryptophan in rs13266634 genetic polymorphism studies of the SLC30A8 gene with type 2 diabetes-mellitus patients featuring a positive family history in the Saudi population. J King Saud Univ Sci . 2021;33(1):101258. doi:10.1016/j.jksus.2020.101258
   Web of Science ®Google Scholar
• Khan IA , Jahan P , Hasan Q , Rao P . Genetic confirmation of T2DM meta-analysis variants studied in gestational diabetes mellitus in an Indian population. Diabetes Metab Syndr . 2019;13(1):688–694. doi:10.1016/j.dsx.2018.11.035 30641791
   PubMed Web of Science ®Google Scholar
• Poy MN , Eliasson L , Krutzfeldt J , et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature . 2004;432(7014):226–230. doi:10.1038/nature03076 15538371
   PubMed Web of Science ®Google Scholar
• Kloosterman WP , Lagendijk AK , Ketting RF , Moulton JD , Plasterk RHA , Carrington JC . Targeted inhibition of miRNA maturation with morpholinos reveals a role for miR-375 in pancreatic islet development. PLoS Biol . 2007;5(8):e203. doi:10.1371/journal.pbio.0050203 17676975
   PubMed Web of Science ®Google Scholar
• Kong L , Zhu J , Han W , et al. Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study. Acta Diabetol . 2011;48(1):61–69. doi:10.1007/s00592-010-0226-0 20857148
   PubMed Web of Science ®Google Scholar
• Sun K , Chang X , Yin L , et al. Expression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus. Mol Med Rep . 2014;9(3):967–972. doi:10.3892/mmr.2013.1872 24366165
   PubMed Web of Science ®Google Scholar
• Association AD. 2. Classification and diagnosis of diabetes: standards of medical care in diabetes—2019. Diabetes Care . 2019;42(Supplement 1):S13–S28. doi:10.2337/dc19-S002 30559228
   PubMed Web of Science ®Google Scholar
• Ludvigsson J . C-peptide in diabetes diagnosis and therapy. Front Biosci (Elite Ed) . 2013;5:214–223. doi:10.2741/e609 23276983
   PubMedGoogle Scholar
• Seyhan AA , Nunez Lopez YO , Xie H , et al. Pancreas-enriched miRNAs are altered in the circulation of subjects with diabetes: a pilot cross-sectional study. Sci Rep . 2016;6(1). doi:10.1038/srep31479
   Web of Science ®Google Scholar
• Zhao H , Guan J , Lee H-M , et al. Up-regulated pancreatic tissue microRNA-375 associates with human type 2 diabetes through beta-cell deficit and islet amyloid deposition. Pancreas . 2010;39(6):843–846. doi:10.1097/MPA.0b013e3181d12613 20467341
   PubMed Web of Science ®Google Scholar
• Liu W , Zhao X , Zhang Y-J , Fang G-W , Xue Y . MicroRNA-375 as a potential serum biomarker for the diagnosis, prognosis, and chemosensitivity prediction of osteosarcoma. J Int Med Res . 2018;46(3):975–983. doi:10.1177/0300060517734114 29115164
   PubMed Web of Science ®Google Scholar
• Lei L , Zhou C , Yang X , Li L . Down-regulation of microRNA-375 regulates adipokines and inhibits inflammatory cytokines by targeting AdipoR2 in non-alcoholic fatty liver disease. Clin Exp Pharmacol Physiol . 2018;45(8):819–831. doi:10.1111/1440-1681.12940 29569260
   PubMed Web of Science ®Google Scholar
• Zhang LX , Jin W , Zheng J , et al. MicroRNA-375 regulates proliferation and apoptosis of glioma cancer cells by inhibiting CTGF-EGFR signaling pathway. Bratisl Lek Listy . 2018;119(1):17–21. doi:10.4149/BLL_2018_004 29405725
   PubMed Web of Science ®Google Scholar
• Alam KJ , Mo J-S , Han S-H , et al. MicroRNA 375 regulates proliferation and migration of colon cancer cells by suppressing the CTGF-EGFR signaling pathway. Int J Cancer . 2017;141(8):1614–1629. doi:10.1002/ijc.30861 28670764
   PubMed Web of Science ®Google Scholar
• Harrandah AM , Fitzpatrick SG , Smith MH , Wang D , Cohen DM , Chan EKL . MicroRNA-375 as a biomarker for malignant transformation in oral lesions. Oral Surg Oral Med Oral Pathol Oral Radiol . 2016;122(6):743–752.e1. doi:10.1016/j.oooo.2016.07.022 27720656
   PubMed Web of Science ®Google Scholar
• Chen L-J , Li X-Y , Zhao Y-Q , et al. Down-regulated microRNA-375 expression as a predictive biomarker in non-small cell lung cancer brain metastasis and its prognostic significance. Pathol Res Pract . 2017;213(8):882–888. doi:10.1016/j.prp.2017.06.012 28688608
   PubMed Web of Science ®Google Scholar
• Yan J , She Q , Shen X , Zhang Y , Liu B , Zhang G . Potential role of MicroRNA-375 as biomarker in human cancers detection: a meta-analysis. Biomed Res Int . 2017;2017:1875843. doi:10.1155/2017/1875843 29259977
   PubMed Web of Science ®Google Scholar
• Ramachandran A , Snehalatha C , Satyavani K , Sivasankari S , Vijay V . Cosegregation of obesity with familial aggregation of type 2 diabetes mellitus. Diabetes Obes Metab . 2000;2(3):149–154. doi:10.1046/j.1463-1326.2000.00067.x 11220550
   PubMed Web of Science ®Google Scholar
• Li JKY , Ng MCY , So WY , et al. Phenotypic and genetic clustering of diabetes and metabolic syndrome in Chinese families with type 2 diabetes mellitus. Diabetes Metab Res Rev . 2006;22(1):46–52. doi:10.1002/dmrr.577 16021651
   PubMed Web of Science ®Google Scholar