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Original Research

Foveal Avascular Zone Does Not Correspond to Choroidal Characteristics in Patients with Diabetic Retinopathy: A Single-Center Cross-Sectional Analysis

, , ORCID Icon, , & ORCID Icon
Pages 2893-2903 | Published online: 28 Jun 2021

References

  • Byeon SH , Kim M , Kwon OW . Ischemia. In: Bernardes R , Cunha-Vaz J , editors. Optical Coherence Tomography a Clinical and Technical Update . Vols. 24–26. Springer-Verlag; 2012:chap 2.
  • Nickla DL , Wallman J . The multifunctional choroid. Prog Retin Eye Res . 2010;29(2):144–168. doi:10.1016/j.preteyeres.2009.12.002 20044062
  • Garcia JM , Lima TT , Louzada RN , Rassi AT , Isaac DL , Avila M . Diabetic macular ischemia diagnosis: comparison between optical coherence tomography angiography and fluorescein angiography. J Ophthalmol . 2016;2016:3989310. doi:10.1155/2016/3989310 27891250
  • Dmuchowska DA , Krasnicki P , Mariak Z . Can optical coherence tomography replace fluorescein angiography in detection of ischemic diabetic maculopathy? Graefes Arch Clin Exp Ophthalmol . 2014;252(5):731–738. doi:10.1007/s00417-013-2518-x 24292702
  • Lutty GA . Diabetic choroidopathy. Vision Res . 2017;139:161–167. doi:10.1016/j.visres.2017.04.011 28535994
  • Melancia D , Vicente A , Cunha JP , Abegão Pinto L , Ferreira J . Diabetic choroidopathy: a review of the current literature. Graefes Arch Clin Exp Ophthalmol . 2016;254(8):1453–1461. doi:10.1007/s00417-016-3360-8 27109344
  • Sun Z , Yang D , Tang Z , Ng DS , Cheung CY . Optical coherence tomography angiography in diabetic retinopathy: an updated review. Eye (Lond) . 2021;35(1):149–161. doi:10.1038/s41433-020-01233-y 33099579
  • Kim M , Ha MJ , Choi SY , Park YH . Choroidal vascularity index in type-2 diabetes analyzed by swept-source optical coherence tomography. Sci Rep . 2018;8(1):70. doi:10.1038/s41598-017-18511-7 29311618
  • Ryu G , Kim I , Sagong M . Topographic analysis of retinal and choroidal microvasculature according to diabetic retinopathy severity using optical coherence tomography angiography. Graefes Arch Clin Exp Ophthalmol . 2021;259(1):61–68. doi:10.1007/s00417-020-04785-7 32648156
  • Krasnicki P , Dmuchowska DA , Proniewska-Skretek E , Dobrzycki S , Mariak Z . Ocular haemodynamics in patients with type 2 diabetes and coronary artery disease. Br J Ophthalmol . 2014;98(5):675–678. doi:10.1136/bjophthalmol-2013-304224 24457359
  • Agrawal R , Ding J , Sen P , et al. Exploring choroidal angioarchitecture in health and disease using choroidal vascularity index. Prog Retin Eye Res . 2020;77:100829. doi:10.1016/j.preteyeres.2020.100829 31927136
  • Sonoda S , Sakamoto T , Yamashita T , et al. Luminal and stromal areas of choroid determined by binarization method of optical coherence tomographic images. Am J Ophthalmol . 2015;159(6):1123–1131.e1. doi:10.1016/j.ajo.2015.03.005 25790737
  • Daruich A , Matet A , Moulin A , et al. Mechanisms of macular edema: beyond the surface. Prog Retin Eye Res . 2018;63:20–68. doi:10.1016/j.preteyeres.2017.10.006 29126927
  • Early Treatment Diabetic Retinopathy Study Research Group. Grading diabetic retinopathy from stereoscopic color fundus photographs–an extension of the modified Airlie House classification. ETDRS report number 10. Ophthalmology . 1991;98(5 Suppl):786–806. doi:10.1016/S0161-6420(13)38012-9 2062513
  • Early Treatment Diabetic Retinopathy Study Research Group. Classification of diabetic retinopathy from fluorescein angiograms. ETDRS report number 11. Ophthalmology . 1991;98(5 Suppl):807–822. doi:10.1016/S0161-6420(13)38013-0 2062514
  • Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema. Early Treatment Diabetic Retinopathy Study report number 1. Arch Ophthalmol . 1985;103(12):1796–1806. doi:10.1001/archopht.1985.01050120030015 2866759
  • Early Treatment Diabetic Retinopathy Study Research Group. Fundus photographic risk factors for progression of diabetic retinopathy. ETDRS report number 12. Ophthalmology . 1991;98(5 Suppl):823–833. doi:10.1016/S0161-6420(13)38014-2 2062515
  • Agrawal R , Gupta P , Tan KA , Cheung CM , Wong TY , Cheng CY . Choroidal vascularity index as a measure of vascular status of the choroid: measurements in healthy eyes from a population-based study. Sci Rep . 2016;6(1):21090. doi:10.1038/srep21090 26868048
  • Sonoda S , Sakamoto T , Yamashita T , et al. Choroidal structure in normal eyes and after photodynamic therapy determined by binarization of optical coherence tomographic images. Invest Ophthalmol Vis Sci . 2014;55(6):3893–3899. doi:10.1167/iovs.14-14447 24894395
  • Gerendas BS , Waldstein SM , Simader C , et al. Three-dimensional automated choroidal volume assessment on standard spectral-domain optical coherence tomography and correlation with the level of diabetic macular edema. Am J Ophthalmol . 2014;158(5):1039–1048. doi:10.1016/j.ajo.2014.08.001 25127697
  • Adhi M , Brewer E , Waheed NK , Duker JS . Analysis of morphological features and vascular layers of choroid in diabetic retinopathy using spectral-domain optical coherence tomography. JAMA Ophthalmol . 2013;131(10):1267–1274. doi:10.1001/jamaophthalmol.2013.4321 23907153
  • Johannesen SK , Viken JN , Vergmann AS , Grauslund J . Optical coherence tomography angiography and microvascular changes in diabetic retinopathy: a systematic review. Acta Ophthalmol . 2019;97(1):7–14. doi:10.1111/aos.13859 30238633
  • Singh SR , Vupparaboina KK , Goud A , Dansingani KK , Chhablani J . Choroidal imaging biomarkers. Surv Ophthalmol . 2019;64(3):312–333. doi:10.1016/j.survophthal.2018.11.002 30496750
  • Iovino C , Pellegrini M , Bernabei F , et al. Choroidal vascularity index: an in-depth analysis of this novel optical coherence tomography parameter. J Clin Med . 2020;9(2):Feb. doi:10.3390/jcm9020595
  • Campos A , Campos EJ , Martins J , Ambrósio AF , Silva R . Viewing the choroid: where we stand, challenges and contradictions in diabetic retinopathy and diabetic macular oedema. Acta Ophthalmol . 2017;95(5):446–459. doi:10.1111/aos.13210 27545332
  • Kim M , Choi SY , Park YH . Quantitative analysis of retinal and choroidal microvascular changes in patients with diabetes. Sci Rep . 2018;8(1):12146. doi:10.1038/s41598-018-30699-w 30108264
  • Gupta C , Tan R , Mishra C , et al. Choroidal structural analysis in eyes with diabetic retinopathy and diabetic macular edema-A novel OCT based imaging biomarker. PLoS One . 2018;13(12):e0207435. doi:10.1371/journal.pone.0207435 30533048
  • Tan KA , Laude A , Yip V , Loo E , Wong EP , Agrawal R . Choroidal vascularity index - a novel optical coherence tomography parameter for disease monitoring in diabetes mellitus? Acta Ophthalmol . 2016;94(7):e612–e616. doi:10.1111/aos.13044 27151819
  • Conrath J , Giorgi R , Raccah D , Ridings B . Foveal avascular zone in diabetic retinopathy: quantitative vs qualitative assessment. Eye (Lond) . 2005;19(3):322–326. doi:10.1038/sj.eye.6701456 15258601
  • Sim DA , Keane PA , Fung S , et al. Quantitative analysis of diabetic macular ischemia using optical coherence tomography. Invest Ophthalmol Vis Sci . 2014;55(1):417–423. doi:10.1167/iovs.13-12677 24398090
  • Lee DH , Kim JT , Jung DW , Joe SG , Yoon YH . The relationship between foveal ischemia and spectral-domain optical coherence tomography findings in ischemic diabetic macular edema. Invest Ophthalmol Vis Sci . 2013;54(2):1080–1085. doi:10.1167/iovs.12-10503 23329668
  • Oh J , Baik DJ , Ahn J . Inter-relationship between retinal and choroidal vasculatures using optical coherence tomography angiography in normal eyes. Eur J Ophthalmol . 2020;30(1):48–57. doi:10.1177/1120672118816225 30516077
  • Nesper PL , Roberts PK , Onishi AC , et al. Quantifying microvascular abnormalities with increasing severity of diabetic retinopathy using optical coherence tomography angiography. Invest Ophthalmol Vis Sci . 2017;58(6):BIO307–BIO315. doi:10.1167/iovs.17-21787 29059262
  • Yazici A , Sogutlu Sari E , Koc R , et al. Alterations of choroidal thickness with diabetic neuropathy. Invest Ophthalmol Vis Sci . 2016;57(4):1518–1522. doi:10.1167/iovs.15-17966 27035624
  • Gärtner J , Fischer F . Experimental autonomic neuropathy in the choroid of streptozotocin-diabetic rats. Electron microscopic observations. Retina . 1989;9(1):49–58. doi:10.1097/00006982-198909010-00007 2717804
  • Fryczkowski AW , Sato SE , Hodes BL . Changes in the diabetic choroidal vasculature: scanning electron microscopy findings. Ann Ophthalmol . 1988;20(8):299–305.3190107
  • Markan A , Agarwal A , Arora A , Bazgain K , Rana V , Gupta V . Novel imaging biomarkers in diabetic retinopathy and diabetic macular edema. Ther Adv Ophthalmol . 2020;12:2515841420950513. doi:10.1177/2515841420950513 32954207
  • Hayreh SS . In vivo choroidal circulation and its watershed zones. Eye (Lond) . 1990;4(Pt 2):273–289. doi:10.1038/eye.1990.39 2199236
  • Rosen RB , Andrade Romo JS , Krawitz BD , et al. Earliest evidence of preclinical diabetic retinopathy revealed using optical coherence tomography angiography perfused capillary density. Am J Ophthalmol . 2019;203:103–115. doi:10.1016/j.ajo.2019.01.012 30689991
  • Ferrara D , Waheed NK , Duker JS . Investigating the choriocapillaris and choroidal vasculature with new optical coherence tomography technologies. Prog Retin Eye Res . 2016;52:130–155. doi:10.1016/j.preteyeres.2015.10.002 26478514
  • Agrawal R , Seen S , Vaishnavi S , et al. Choroidal vascularity index using swept-source and spectral-domain optical coherence tomography: a Comparative Study. Ophthalmic Surg Lasers Imaging Retina . 2019;50(2):e26–e32. doi:10.3928/23258160-20190129-15 30768226