287
Views
0
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Combined Exercise Training Promotes More Benefits on Cardiovascular Autonomic Modulation in Ovariectomized Rats Than Isolated Aerobic or Resistance Training

ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 1903-1913 | Received 20 Aug 2022, Accepted 10 Apr 2023, Published online: 26 Jun 2023

References

  • World Health Organization. Cardiovascular diseases (CVDs). Available from: https://www.who.int/newsroom/fact-sheets/detail/cardiovascular-diseases-(cvds). Accessed October 25, 2022.
  • Vogel B, Acevedo M, Appelman Y, et al. The Lancet women and cardiovascular disease Commission: reducing the global burden by 2030. Lancet. 2021;397(10292):2385–2438. doi:10.1016/S0140-6736(21)00684-X
  • de Jong M, Woodward M, Peters SAE. Diabetes, glycated hemoglobin, and the risk of myocardial infarction in women and men: a prospective cohort study of the UK biobank. Diabetes Care. 2020;43(9):2050–2059. doi:10.2337/DC19-2363
  • Tsao CW, Aday AW, Almarzooq ZI, et al. Heart disease and stroke statistics-2022 update: a report from the American heart association. Circulation. 2022;145(8):E153–E639. doi:10.1161/CIR.0000000000001052
  • Shimojo GL, Palma RK, Brito JO, Sanches IC, Irigoyen MC, de Angelis K. Dynamic resistance training decreases sympathetic tone in hypertensive ovariectomized rats. Braz J Med Biol Res. 2015;48(6):523–527. doi:10.1590/1414431X20154387
  • Flues K, Paulini J, Brito SS, et al. Exercise training associated with estrogen therapy induced cardiovascular benefits after ovarian hormones deprivation. Maturitas. 2010;65(3):267–271. doi:10.1016/j.maturitas.2009.11.007
  • Takezawa H, Hayashi H, Sano H, Ebihara S. Estrous-related variations of blood pressure and heart rate in female rats - PubMed. Front Med Bioeng Eng. 1994;6(2):131–137.
  • Takezawa H, Hayashi H, Sano H, Saito H, Ebihara S. Circadian and estrous cycle dependent variations in blood pressure and heart rate in female rats. Am J Physiol. 1994;267(5):Pt 2. doi:10.1152/AJPREGU.1994.267.5.R1250
  • Angelis De K, Do M, Brasileiro S, et al. Sistema nervoso autônomo e doença cardiovascular. Revista da Sociedade de Cardiologia do Rio Grande do Sul. 2004;13(03):1–7. doi:10.1126/science.150.3699.971
  • Porta A, Żebrowski J. Inferring cardiovascular control from spontaneous variability. Auton Neurosci. 2013;178(1–2):1–3. doi:10.1016/j.autneu.2013.05.006
  • Joaquim LF, Salgado HC, Fazan Júnior R. Variabilidade da pressão arterial e freqüência cardíaca, e sensibilidade do barorreflexo, em animais geneticamente manipulados. Rev Bras Hipert. 2005;12(1):36–40.
  • Suarez-Roca H, Mamoun N, Sigurdson MI, Maixner W. Baroreceptor modulation of the cardiovascular system, pain, consciousness, and cognition. Compr Physiol. 2021;11(2):1373. doi:10.1002/CPHY.C190038
  • Saladini F, Di Marco A, Palatini P. Autonomic dysfunction: how to identify and when to treat? High Blood Press Cardiovasc Prev. 2016;23(3):237–243. doi:10.1007/s40292-016-0162-3
  • Flores LJ, Figueroa D, Sanches IC, et al. Effects of exercise training on autonomic dysfunction management in an experimental model of menopause and myocardial infarction. Menopause. 2010;17(4):1. doi:10.1097/gme.0b013e3181cdebc9
  • Chodzko-Zajko WJ, Proctor DN, Fiatarone Singh MA, et al. Exercise and physical activity for older adults. Med Sci Sports Exerc. 2009;41(7):1510–1530. doi:10.1249/MSS.0b013e3182A0c95c
  • Sanches IC, Conti FF, Sartori M, Irigoyen MC, De Angelis K. Standardization of resistance exercise training: effects in diabetic ovariectomized rats. Int J Sports Med. 2014;35(4):323–329. doi:10.1055/s-0033-1351254
  • De Oliveira brito-monzani J, Stoyell-Conti FF, Shecaira TP, et al. Aerobic or resistance training improves autonomic control of circulation in oophorectomized rats with cardiometabolic dysfunctions: impact on renal oxidative stress. Exp Gerontol. 2021:145. doi:10.1016/J.EXGER.2020.111181
  • da Palma RK, Moraes-Silva IC, da Dias DS, et al. Resistance or aerobic training decreases blood pressure and improves cardiovascular autonomic control and oxidative stress in hypertensive menopausal rats. J Appl Physiol. 2016;121(4):130. doi:10.1152/japplphysiol.00130.2016
  • Whelton PK, Carey RM, Aronow WS, et al. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNAGuidelineforthe prevention, detection, evaluation, and management of high blood pressure in adults: executive summary: a report of the American College of Cardiology/American Heart Association Task F. Hypertension. 2018;71(6):1269–1324. doi:10.1161/HYP.0000000000000066
  • Visseren FLJ, MacH F, Smulders YM, et al. 2021 ESC Guidelines on cardiovascular disease prevention in clinical practiceDeveloped by the task force for cardiovascular disease prevention in clinical practice with representatives of the European Society of Cardiology and 12 medical societies With the special contribution of the European Association of Preventive Cardiology (EAPC). Eur Heart J. 2021;42(34):3227–3337. doi:10.1093/EURHEARTJ/EHAB484
  • Shimojo GL, da Silva Dias D, Malfitano C, et al. Combined aerobic and resistance exercise training improve hypertension associated with menopause. Front Physiol. 2018;9:1471. doi:10.3389/fphys.2018.01471
  • Conti FF, de Brito JO, Bernardes N, et al. Positive effect of combined exercise training in a model of metabolic syndrome and menopause: autonomic, inflammatory, and oxidative stress evaluations. Am J Physiol Regul Integr Comp Physiol. 2015;309(12):R1532–R1539. doi:10.1152/ajpregu.00076.2015
  • Sanches IC, Conti FF, Bernardes N, et al. Impact of combined exercise training on cardiovascular autonomic control and mortality in diabetic ovariectomized rats. J Appl Physiol. 2015;119(6):656–662. doi:10.1152/japplphysiol.00883.2014
  • Ferreira MJ, Sanches IC, Jorge L, Llesuy SF, Irigoyen MC, de Angelis K. Ovarian status modulates cardiovascular autonomic control and oxidative stress in target organs. Biol Sex Differ. 2020;11(1). doi:10.1186/S13293-020-00290-Y
  • Irigoyen MC, Paulini J, Flores LJF, et al. Exercise training improves baroreflex sensitivity associated with oxidative stress reduction in ovariectomized rats. Hypertension. 2005;46(4):998–1003. doi:10.1161/01.HYP.0000176238.90688.6b
  • Sanches IC, De Oliveira Brito J, Candido GO, et al. Cardiometabolic benefits of exercise training in an experimental model of metabolic syndrome and menopause. Menopause. 2012;19(5):562–568. doi:10.1097/gme.0b013e3182358c9c
  • Brito JO, Ponciano K, Figueroa D, et al. Parasympathetic dysfunction is associated with insulin resistance in fructose-fed female rats. Braz J Med Biol Res. 2008;41(9):804–808. doi:10.1590/S0100-879X2008005000030
  • Bonora E, Moghetti P, Zancanaro C, et al. Estimates of in vivo insulin action in man: comparison of insulin tolerance tests with euglycemic and hyperglycemic glucose clamp studies. J Clin Endocrinol Metab. 1989;68(2):374–378. doi:10.1210/jcem-68-2-374
  • Bertagnolli M, Campos C, Schenkel PC, et al. Baroreflex sensitivity improvement is associated with decreased oxidative stress in trained spontaneously hypertensive rat. J Hypertens. 2006;24(12):2437–2443. doi:10.1097/01.HJH.0000251905.08547.17
  • Montano N, Porta A, Cogliati C, et al. Heart rate variability explored in the frequency domain: a tool to investigate the link between heart and behavior. Neurosci Biobehav Rev. 2009;33(2):71–80. doi:10.1016/j.neubiorev.2008.07.006
  • Rodrigues B, Figueroa DM, Mostarda CT, Heeren MV, Irigoyen MC, De Angelis K. Maximal exercise test is a useful method for physical capacity and oxygen consumption determination in streptozotocin-diabetic rats. Cardiovasc Diabetol. 2007;6(1):38. doi:10.1186/1475-2840-6-38
  • Myers J, Gullestad L, Vagelos R, et al. Clinical, hemodynamic, and cardiopulmonary exercise test determinants of survival in patients referred for evaluation of heart failure. Ann Intern Med. 1998;129(4):286–293. doi:10.7326/0003-4819-129-4-199808150-00004
  • Freire Machi J, da Silva Dias D, Freitas S, et al. Impact of aging on cardiac function in a female rat model of menopause: role of autonomic control, inflammation, and oxidative stress. Clin Interv Aging. 2016;11:341. doi:10.2147/CIA.S88441
  • Stunes AK, Erben RG, Schüler C, et al. Skeletal effects of plyometric exercise and metformin in ovariectomized rats. Bone. 2020;132:115193. doi:10.1016/J.BONE.2019.115193
  • Frontoni S, Bracaglia D, Gigli F. Relationship between autonomic dysfunction, insulin resistance and hypertension, in diabetes. Nutr Metab Cardiovasc Dis. 2005;15(6):441449. doi:10.1016/J.NUMECD.2005.06.010
  • Lingvay I, Sumithran P, Cohen RV, le Roux CW. Obesity management as a primary treatment goal for type 2 diabetes: time to reframe the conversation. Lancet. 2022;399(10322):394–405. doi:10.1016/S0140-6736(21)01919-X
  • Véras-Silva A, Mattos K, Gava N, Brum P, Negrão C, Krieger E. Low-intensity exercise training decreases cardiac output and hypertension in spontaneously hypertensive rats. Am J Physiol. 1997;273(6):H2627–31. doi:10.1152/AJPHEART.1997.273.6.H2627
  • Negrão C, Moreira E, Santos M, Farah V, Krieger E. Vagal function impairment after exercise training. J Appl Physiol. 1992;72(5):1749–1753. doi:10.1152/JAPPL.1992.72.5.1749
  • Guyenet PG. The sympathetic control of blood pressure. Nat Rev Neurosci. 2006;7(5):335–346. doi:10.1038/NRN1902
  • Michelini LC, Stern JE. Exercise-induced neuronal plasticity in central autonomic networks: role in cardiovascular control. Exp Physiol. 2009;94(9):947–960. doi:10.1113/expphysiol.2009.047449
  • Michelini LC. Differential effects of vasopressinergic and oxytocinergic pre-autonomic neurons on circulatory control: reflex mechanisms and changes during exercise. Clin Exp Pharmacol Physiol. 2007;34(4):369–376. doi:10.1111/j.1440-1681.2007.04589.x
  • Michelini LC, Morris M. Endogenous vasopressin modulates the cardiovascular responses to exercise. In: Annals of the New York Academy of Sciences. Vol. 897. New York Academy of Sciences;1999:198–211. doi:10.1111/j.1749-6632.1999.tb07892.x
  • Santos CR, Ruggeri A, Ceroni A, Michelini LC. Exercise training abrogates age-dependent loss of hypothalamic oxytocinergic circuitry and maintains high parasympathetic activity. J Neuroendocrinol. 2018;30(8):e12601. doi:10.1111/jne.12601
  • Hopf HB, Skyschally A, Heusch G, Peters J. Low-frequency spectral power of heart rate variability is not a specific marker of cardiac sympathetic modulation. Anesthesiology. 1995;82(3):609–619. doi:10.1097/00000542-199503000-00002
  • P B, M RJ, C MA, et al. Assessment of autonomic function in humans by heart rate spectral analysis. Am J Physiol. 1985;248(1):Pt 2. doi:10.1152/AJPHEART.1985.248.1.H151
  • De Maria B, Bari V, Sgoifo A, et al. Concomitant evaluation of heart period and QT interval variability spectral markers to typify cardiac control in humans and rats. Front Physiol. 2019;10:1478. doi:10.3389/FPHYS.2019.01478/BIBTEX
  • Bernardes N, Da D, Dias S, Dias S. Exercise training improves cardiovascular health in post menopause women; 2008.
  • Quinteiro H, Buzin M, Conti FF, et al. Aerobic exercise training promotes additional cardiac benefits better than resistance exercise training in postmenopausal rats with diabetes. Menopause. 2015;22(5):534–541. doi:10.1097/GME.0000000000000344
  • Higa KT, Mori E, Viana FF, Morris M, Michelini LC. Baroreflex control of heart rate by oxytocin in the solitary-vagal complex. Am J Physiol Regul Integr Comp Physiol. 2002;282(2):51–52. doi:10.1152/ajpregu.00806.2000
  • Zaki ME. Effects of whole body vibration and resistance training on bone mineral density and anthropometry in obese postmenopausal women. J Osteoporos. 2014;2014:702589. doi:10.1155/2014/702589
  • Stanisic J, Koricanac G, Kostic M, et al. Low-intensity exercise in the prevention of cardiac insulin resistance-related inflammation and disturbances in NOS and MMP-9 regulation in fructose-fed ovariectomized rats. Appl Physiol Nutr Metab. 2019;44(11):1219–1229. doi:10.1139/apnm-2018-0785