References
- Williams WW, Salem RM, McKnight AJ, et al. Association testing of previously reported variants in a large case-control meta-analysis of diabetic nephropathy. Diabetes. 2012;61(8):2187–2194. doi:10.2337/db11-0751
- Feng B, Lu Y, Ye L, Yin L, Zhou Y, Chen A. Mendelian randomization study supports the causal association between serum cystatin C and risk of diabetic nephropathy. Front Endocrinol. 2022;13:1043174. doi:10.3389/fendo.2022.1043174
- Gan J, Zheng Y, Yu Q, et al. Serum lipocalin-2 levels are increased and independently associated with early-stage renal damage and carotid atherosclerotic plaque in patients with T2DM. Front Endocrinol. 2022;13:855616. doi:10.3389/fendo.2022.855616
- Reiss AB, Miyawaki N, Moon J, et al. CKD, arterial calcification, atherosclerosis and bone health: inter-relationships and controversies. Atherosclerosis. 2018;278:49–59. doi:10.1016/j.atherosclerosis.2018.08.046
- Houeiss P, Njeim R, Tamim H, et al. Urinary 20-HETE: a prospective Non-Invasive prognostic and diagnostic marker for diabetic kidney disease. J Adv Res. 2023;44:109–117. doi:10.1016/j.jare.2022.04.013
- Wei L, Han Y, Tu C. Molecular pathways of diabetic kidney disease inferred from proteomics. Diabetes Metab Syndr Obes. 2023;16:117–128. doi:10.2147/DMSO.S392888
- Lin Z, Zhang D, Zhang X, et al. Extracellular status of thrombospondin-2 in type 2 diabetes mellitus and utility as a biomarker in the determination of early diabetic kidney disease. BMC Nephrol. 2023;24(1):154. doi:10.1186/s12882-023-03216-z
- Tu Y, Yu H, Zhang P, et al. Decreased serum CA19-9 is associated with improvement of insulin resistance and metabolic control in patients with obesity and type 2 diabetes after Roux-en-Y gastric bypass. J Diabetes Investig. 2014;5(6):694–700. doi:10.1111/jdi.12200
- Scarà S, Bottoni P, Scatena R. CA 19-9: biochemical and clinical aspects. Adv Exp Med Biol. 2015;867:247–260. doi:10.1007/978-94-017-7215-0_15
- Li Z, Wang J, Han X, et al. Association between cancer antigen 19-9 and diabetes risk: a prospective and Mendelian randomization study. J Diabetes Investig. 2020;11(3):585–593. doi:10.1111/jdi.13166
- Sharma JB, Sharma S, Usha BR, Gupta A, Kumar S, Mukhopadhyay AK. A cross-sectional study of tumor markers during normal and high-risk pregnancies. Int J Gynaecol Obstet. 2015;129(3):203–206. doi:10.1016/j.ijgo.2014.12.014
- Zayed AA, Beano AM, Amer FN, et al. Serum levels of carcinoembryonic antigen in patients with type 2 diabetes. Endocr Pract. 2016;22(11):1310–1318. doi:10.4158/EP161221.OR
- Du R, Cheng D, Lin L, et al. Association between serum CA 19-9 and metabolic syndrome: a cross-sectional study. J Diabetes. 2017;9(11):1040–1047. doi:10.1111/1753-0407.12523
- Son DH, Lee HS, Lee YJ. Association between serum carbohydrate antigen 19-9 levels and leukoaraiosis in middle-aged and older adults: a cross-sectional study. Atherosclerosis. 2020;292:188–192. doi:10.1016/j.atherosclerosis.2019.11.003
- Park B, Lee YJ. Association of serum carbohydrate antigen 19-9 level with arterial stiffness and coronary artery calcification in middle-aged and older adults: a cross-sectional study. J Hypertens. 2020;38(1):95–101. doi:10.1097/HJH.0000000000002217
- Lin B, Ma YY, Wang JW. Nano-technological approaches for targeting kidney diseases with focus on diabetic nephropathy: recent progress, and future perspectives. Front Bioeng Biotechnol. 2022;10:870049. doi:10.3389/fbioe.2022.870049
- Lee KY, Sohn YH, Baik JS, Kim GW, Kim JS. Arterial pulsatility as an index of cerebral microangiopathy in diabetes. Stroke. 2000;31(5):1111–1115. doi:10.1161/01.str.31.5.1111
- Nakamura N, Aoji O, Yoshikawa T, et al. Elevated serum CA19-9 levels in poorly controlled diabetic patients. Jpn J Med. 1986;25(3):278–280. doi:10.2169/internalmedicine1962.25.278
- Gul K, Nas S, Ozdemir D, Gumus M, Ersoy R, Cakir B. CA 19-9 level in patients with type 2 diabetes mellitus and its relation to the metabolic control and microvascular complications. Am J Med Sci. 2011;341(1):28–32. doi:10.1097/MAJ.0b013e3181f0e2a0
- Kim SH, Baek CO, Lee KA, et al. Clinical implication of elevated CA 19-9 level and the relationship with glucose control state in patients with type 2 diabetes. Endocrine. 2014;46(2):249–255. doi:10.1007/s12020-013-0058-0
- Cui L, Lv N, Li B, et al. Serum CA 19-9 level is correlated to the clinical characteristics and chronic complications of patients newly diagnosed with type 2 diabetes mellitus. Exp Clin Endocrinol Diabetes. 2021;129(8):581–586. doi:10.1055/a-0994-9970
- Tong W, Gao H, Wei X, et al. Correlation of serum CA199 levels with glycemic control and microvascular complications in patients with type 2 diabetes mellitus. Am J Transl Res. 2021;13(4):3302–3308.
- Turgutalp K, Ozhan O, Helvacı I, et al. Serum levels of cancer biomarkers in diabetic and non-diabetic proteinuric patients: a preliminary study. Clin Chem Lab Med. 2013;51(4):889–895. doi:10.1515/cclm-2012-0657
- Guo J, Sun C, Wang B, et al. Associations between vitamin D and β-cell function and colorectal cancer-associated tumor markers in Chinese type 2 diabetic patients with albuminuria. Clin Lab. 2019;65(4):641–649. doi:10.7754/Clin.Lab.2019.181111
- Wu Y, Wan Q, Xu Y, et al. Lower visceral fat area in patients with type 2 diabetic peripheral neuropathy. Diabetes Metab Syndr Obes. 2022;15:3639–3654. doi:10.2147/DMSO.S388330
- Fitch KV, Stanley TL, Looby SE, Rope AM, Grinspoon SK. Relationship between neck circumference and cardiometabolic parameters in HIV-infected and non-HIV-infected adults. Diabetes Care. 2011;34(4):1026–1031. doi:10.2337/dc10-1983
- Levey AS, Stevens LA, Schmid CH, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med. 2009;150(9):604–612. doi:10.7326/0003-4819-150-9-200905050-00006
- Yan P, Zhang Z, Wan Q, et al. Association of serum uric acid with bone mineral density and clinical fractures in Chinese type 2 diabetes mellitus patients: a cross-sectional study. Clin Chim Acta. 2018;486:76–85. doi:10.1016/j.cca.2018.07.033
- Feng F, Tian Y, Xu G, et al. Diagnostic and prognostic value of CEA, CA19-9, AFP and CA125 for early gastric cancer. BMC Cancer. 2017;17(1):737. doi:10.1186/s12885-017-3738-y
- Chen MM, Jia JH, Tan YJ, et al. Shen-Qi-Jiang-Tang granule ameliorates diabetic nephropathy via modulating tumor necrosis factor signaling pathway. J Ethnopharmacol. 2023;303:116031. doi:10.1016/j.jep.2022.116031
- Tahrani AA, Ali A, Raymond NT, et al. Obstructive sleep apnea and diabetic nephropathy: a cohort study. Diabetes Care. 2013;36(11):3718–3725. doi:10.2337/dc13-0450
- Yu H, Li R, Zhang L, Chen H, Bao Y, Jia W. Serum CA19-9 level associated with metabolic control and pancreatic beta cell function in diabetic patients. Exp Diabetes Res. 2012;2012:745189. doi:10.1155/2012/745189
- Shang X, Song C, Du X, Shao H, Xu D, Wang X. The serum levels of tumor marker CA19-9, CEA, CA72-4, and NSE in type 2 diabetes without malignancy and the relations to the metabolic control. Saudi Med J. 2017;38(2):204–208. doi:10.15537/smj.2017.2.15649
- Du R, Sun W, Lin L, et al. Serum CA 19-9 and risk of incident diabetes in middle-aged and elderly Chinese: a prospective cohort study. Acta Diabetol. 2017;54(2):201–208. doi:10.1007/s00592-016-0937-y
- Huang Y, Xu Y, Bi Y, et al. Relationship between CA 19-9 levels and glucose regulation in a middle-aged and elderly Chinese population. J Diabetes. 2012;4(2):147–152. doi:10.1111/j.1753-0407.2011.00179.x
- Cheng YC, Li YH, Hsu CY, Lee IT. Synergistic association of carcinoembryonic antigen and carbohydrate antigen 19-9 on the risk of abnormal glucose regulation. Diabetes Metab Syndr Obes. 2020;13:1933–1942. doi:10.2147/DMSO.S256223
- Ankit BS, Agrawal R, Gadhwal A, Chahar C, Agrawal RP. The influence of metformin on serum carbohydrate antigen 19-9 (CA 19-9) levels in type 2 diabetes mellitus patients. J Assoc Physicians India. 2018;66(3):38–41.
- Liu XY. The high prevalence of short-term elevation of tumor markers due to hyperglycemia in diabetic patients. Diabetes Metab Syndr Obes. 2022;15:1113–1122. doi:10.2147/DMSO.S350599
- Hao M, Head WS, Gunawardana SC, Hasty AH, Piston DW. Direct effect of cholesterol on insulin secretion: a novel mechanism for pancreatic beta-cell dysfunction. Diabetes. 2007;56(9):2328–2338. doi:10.2337/db07-0056
- Li Z, Huang Q, Sun L, Bao T, Dai Z. Atherogenic index in type 2 diabetes and its relationship with chronic microvascular complications. Int J Endocrinol. 2018;2018:1765835. doi:10.1155/2018/1765835
- Sakashita M, Tanaka T, Inagi R. Metabolic changes and oxidative stress in diabetic kidney disease. Antioxidants. 2021;10(7):1143. doi:10.3390/antiox10071143
- Bjornstad P, Wiromrat P, Johnson RJ, et al. Serum uromodulin predicts less coronary artery calcification and diabetic kidney disease over 12 years in adults with type 1 diabetes: the CACTI study. Diabetes Care. 2019;42(2):297–302. doi:10.2337/dc18-1527
- Harkin C, Cobice D, Brockbank S, et al. Biomarkers for detecting kidney dysfunction in type-2 diabetics and diabetic nephropathy subjects: a case-control study to identify potential biomarkers of DN to stratify risk of progression in T2D patients. Front Endocrinol. 2022;13:887237. doi:10.3389/fendo.2022.887237
- Weir MR. Microalbuminuria and cardiovascular disease. Clin J Am Soc Nephrol. 2007;2(3):581–590. doi:10.2215/CJN.03190906
- Lee SP, Sung IK, Kim JH, Lee SY, Park HS, Shim CS. Usefulness of carbohydrate antigen 19-9 test in healthy people and necessity of medical follow-up in individuals with elevated carbohydrate antigen 19-9 level. Korean J Fam Med. 2019;40(5):314–322. doi:10.4082/kjfm.18.0057
- Varol E, Ozaydin M, Dogan A, Kosar F. Tumour marker levels in patients with chronic heart failure. Eur J Heart Fail. 2005;7(5):840–843. doi:10.1016/j.ejheart.2004.12.008