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Original Research

Incidence and Predictors of Opportunistic Infections Among Adult HIV Infected Patients on Anti-Retroviral Therapy at Dessie Comprehensive Specialized Hospital, Ethiopia: A Retrospective Follow-Up Study

, , ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 195-206 | Published online: 19 Apr 2022

References

  • Gona P, Van Dyke RB, Williams PL, et al. Incidence of opportunistic and other infections in HIV-infected children in the HAART era. JAMA. 2006;296(3):292–300. doi:10.1001/jama.296.3.292
  • Iroezindu M, Ofondu E, Hausler H, Van Wyk B. Prevalence and risk factors for opportunistic infections in HIV patients receiving antiretroviral therapy in a resource-limited setting in Nigeria. J AIDs Clin Res. 2013;3:2.
  • Podlekareva D, Mocroft A, Dragsted UB, et al. Factors associated with the development of opportunistic infections in HIV-1–infected adults with high CD4+ cell counts: a EuroSIDA study. J Infect Dis. 2006;194(5):633–641.
  • WHO. Global health sector strategy on HIV. 2016–2021; 2019. Available from: https://wwwwhoint/news-room/fact-sheets/detail/hiv-aids. Accessed March 29, 2022.
  • Kharsany AB, Karim QA. HIV infection and AIDS in sub-Saharan Africa: current status, challenges and opportunities. Open AIDS J. 2016;10:34.
  • Low A, Gavriilidis G, Larke N, et al. Incidence of opportunistic infections and the impact of antiretroviral therapy among HIV-infected adults in low-and middle-income countries: a systematic review and meta-analysis. Clin Infect Dis. 2016;62(12):1595–1603.
  • Ethiopian Public Health Institute and ICAP at Columbia University. Ethiopia Population-Based HIV Impact Assessment (EPHIA). Summary Sheet: Preliminary Findings; 2017–2018. 2018:4–7.
  • IeDEA T. Immunodeficiency at the start of combination antiretroviral therapy in low-, middle-and high-income countries. J Acquired Immune Deficiency Syndromes. 2014;65(1):e8.
  • Control CfD, Prevention. Guidelines for the Prevention and Treatment of opportunistic Infections in HIV-infected Adults and Adolescents. MMWR. 2009;58(4):1–206.
  • Edwards LA. Establishing a Pastoral Care Ministry for Those Infected and Affected by HIV/AIDS at the Robert Pinn Memorial Baptist Church. Eastern University; 2015.
  • Seyler C, Messou E, Gabillard D, Inwoley A, Alioum A, Anglaret X. Morbidity before and after HAART initiation in Sub-Saharan African HIV-infected adults: a recurrent event analysis. AIDS Res Hum Retroviruses. 2007;23(11):1338–1347.
  • Zhou J, Paton N, Ditangco R. AIDS-defining illness diagnosed within 90 days after starting highly active antiretroviral therapy among patients from the TREAT Asia HIV Observational Database. Int J STD AIDS. 2007;18(7):446–452.
  • Arefaine ZG, Abebe S, Bekele E, Adem A, Adama Y. Incidence and predictors of HIV related opportunistic infections after initiation of highly active antiretroviral therapy at Ayder Referral Hospital, Mekelle, Ethiopia: a retrospective single centered cohort study. PLoS One. 2020;15(4):e0229757.
  • Moges N, Kassa G. Prevalence of opportunistic infections and associated factors among HIV positive patients taking anti-retroviral therapy in DebreMarkos Referral Hospital, Northwest Ethiopia. J AIDs Clin Res. 2014;5(5):1–300.
  • World Health Organization. WHO Case Definitions of HIV for Surveillance and Revised Clinical Staging and Immunological Classification of HIV-Related Disease in Adults and Children. World Health Organization; 2007.
  • Mariam ZT, Abebe G, Mulu A. Opportunistic and other intestinal parasitic infections in AIDS patients, HIV seropositive healthy carriers and HIV seronegative individuals in southwest Ethiopia. East Afr J Public Health. 2008;5(3):169–173.
  • Nsagha DS, Njunda AL, Assob NJC, Ayima CW, Tanue EA, Kwenti TE. Intestinal parasitic infections in relation to CD4+ T cell counts and diarrhea in HIV/AIDS patients with or without antiretroviral therapy in Cameroon. BMC Infect Dis. 2015;16(1):1–10.
  • Patel SD, Javadekar TB, Kinariwala D. Enteric opportunistic parasitic infections in HIV seropositive patients at tertiary care teaching hospital. Natl J Med Res. 2015;5(3):190–194.
  • Shenoy N, Ramapuram JT, Shenoy A, Ahmed J, Srikant N. Incidence of opportunistic infections among HIV-positive adults on highly active antiretroviral therapy in a teaching hospital, India: prospective study. J Int Assoc Providers AIDS Care. 2017;16(3):309–311.
  • Sun H, Chen M, Hsieh S, et al. Changes in the clinical spectrum of opportunistic illnesses in persons with HIV infection in Taiwan in the era of highly active antiretroviral therapy. Jpn J Infect Dis. 2006;59(5):311.
  • Shearer K, Maskew M, Ajayi T, et al. Incidence and predictors of herpes zoster among antiretroviral therapy-naive patients initiating HIV treatment in Johannesburg, South Africa. Int J Infect Dis. 2014;23:56–62.
  • Ghate M, Deshpande S, Tripathy S, et al. Incidence of common opportunistic infections in HIV-infected individuals in Pune, India: analysis by stages of immunosuppression represented by CD4 counts. Int j Infect Dis. 2009;13(1):e1–e8.
  • De Beaudrap P, Etard J-F, Diouf A, et al. Incidence and determinants of new AIDS-defining illnesses after HAART initiation in a Senegalese cohort. BMC Infect Dis. 2010;10(1):1–9.
  • Candiani T, Pinto J, Cardoso CAA, et al. Impact of highly active antiretroviral therapy (HAART) on the incidence of opportunistic infections, hospitalizations and mortality among children and adolescents living with HIV/AIDS in Belo Horizonte, Minas Gerais State, Brazil. Cadernos de Saúde Pública. 2007;23:S414–S23.
  • Buchacz K, Lau B, Jing Y, et al. Incidence of AIDS-defining opportunistic infections in a multicohort analysis of HIV-infected persons in the United States and Canada, 2000–2010. J Infect Dis. 2016;214(6):862–872.
  • Sabasaba A, Mwambi H, Somi G, Ramadhani A, Mahande MJ. Effect of isoniazid preventive therapy on tuberculosis incidence and associated risk factors among HIV infected adults in Tanzania: a retrospective cohort study. BMC Infect Dis. 2019;19(1):1–8.
  • Dalbo M, Tamiso A. Incidence and predictors of tuberculosis among HIV/AIDS infected patients: a five-year retrospective follow-up study. Adv Infect Dis. 2016;6(02):70.
  • Wachamo D, Bonja F. Magnitude of Opportunistic Infections and Associated Factors Among HIV-Positive Adults on ART at Selected Public Hospitals in Sidama National Regional State, Southern Ethiopia. HIV/AIDS. 2020;12:479.
  • Mocroft A, Youle M, Phillips AN, et al. The incidence of AIDS-defining illnesses in 4883 patients with human immunodeficiency virus infection. Arch Intern Med. 1998;158(5):491–497.
  • Damtie D, Yismaw G, Woldeyohannes D, Anagaw B. Common opportunistic infections and their CD4 cell correlates among HIV-infected patients attending at antiretroviral therapy clinic of Gondar University Hospital, Northwest Ethiopia. BMC Res Notes. 2013;6(1):1–7.
  • Tewachew AS, Mekonnen WN, Mekuria AD, Amare YE. Determinants of Opportunistic Infections Among HIV-Positive Patients on HAART in Debre Berhan Referral Hospital, North Shoa Zone, Ethiopia, 2020: a Case–Control Study. HIV/AIDS. 2021;13:337.
  • Alene KA, Nega A, Taye BW. Incidence and predictors of tuberculosis among adult people living with human immunodeficiency virus at the University of Gondar Referral Hospital, Northwest Ethiopia. BMC Infect Dis. 2013;13(1):1–9.
  • Lawn SD, Badri M, Wood R. Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort. Aids. 2005;19(18):2109–2116.
  • Melkamu H, Seyoum B, Dessie Y. Determinants of tuberculosis infection among adult HIV positives attending clinical care in western Ethiopia: a case-control study. AIDS Res Treat. 2013;2013:64.
  • Diaz A, Del Romero J, Rodriguez C, et al. Effects of region of birth, educational level and age on late presentation among men who have sex with men newly diagnosed with HIV in a network of STI/HIV counselling and testing clinics in Spain. Eurosurveillance. 2015;20(14):21088.
  • Sobrino-Vegas P, Miguel LG-S, Caro-Murillo AM, et al. Delayed diagnosis of HIV infection in a multicenter cohort: prevalence, risk factors, response to HAART and impact on mortality. Curr HIV Res. 2009;7(2):224–230.
  • Ford N, Vitoria M, Hirnschall G, Doherty M. Getting to zero HIV deaths: progress, challenges and ways forward. J Int AIDS Soc. 2013;16(1):54.
  • Temesgen B, Kibret GD, Alamirew NM, et al. Incidence and predictors of tuberculosis among HIV-positive adults on antiretroviral therapy at Debre Markos referral hospital, Northwest Ethiopia: a retrospective record review. BMC Public Health. 2019;19(1):1–9.