142
Views
6
CrossRef citations to date
0
Altmetric
Clinical Trial Report

Comparison of extracorporeal cellular therapy (ELAD®) vs standard of care in a randomized controlled clinical trial in treating Chinese subjects with acute-on-chronic liver failure

, , , , , , , , & show all
Pages 139-152 | Published online: 16 Nov 2018

References

  • Chinese Medical Association-Chinese Society of Infectious and Parasitic diseases in conjunction with Chinese Society of Hepatic DiseaseViral hepatitis prevention and treatment programsZhonghua Gan Zang Bing Za Zhi20008324329
  • Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical AssociationSevere Liver Diseases and Artificial Liver Group, Chinese Society of Hepatology, Chinese Medical Association. Diagnostic and treatment guidelines for liver failureZhonghua Gan Zang Bing Za Zhi20061464364616995974
  • SarinSKKumarAAlmeidaJAAcute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL)Hepatol Int20093126928219669378
  • LiQYuanGYTangKCLiuGWWangRCaoWKPrognostic factors for chronic severe hepatitis and construction of a prognostic modelHepatobiliary Pancreat Dis Int200871404418234637
  • SussmanNLGislasonGTConlinCAKellyJHThe Hepatix extra-corporeal liver assist device: initial clinical experienceArtif Organs19941853903968037614
  • EllisAJHughesRDWendonJAPilot-controlled trial of the extracorporeal liver assist device in acute liver failureHepatology1996246144614518938179
  • MillisJMCroninDCJohnsonRInitial experience with the modified extracorporeal liver-assist device for patients with fulminant hepatic failure: system modifications and clinical impactTransplantation200274121735174612499890
  • World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjectsJAMA2000284233043304511122593
  • LandeenLKLapetodaJvan AllenJHerediaNBrothertonJAshleyRP1104: expression of liver-specific cytochrome P450 isoenzymes and oxygenases in C3A cells prior to and after treatment with the ELAD liver support systemJ Hepatol201562Suppl 2S764
  • BrothertonJHeDAsslaniSMillisMELAD® cellular and system performance improvements [AASLD abstract 855]Hepatology200746Suppl 1615A616A17879364
  • BedardPWLapetodaJvan AllenJHerediaNMichalopoulosGKLandeenLKELAD VTL C3A cells may impact liver regeneration through secreted factorsAASLD – The Liver MeetingNovember 13–17, 2015San Francisco, CA, USA
  • KamathPSWiesnerRHMalinchocMA model to predict survival in patients with end-stage liver diseaseHepatology200133246447011172350
  • LachinJMIntroduction to sample size determination and power analysis for clinical trialsControl Clin Trials198122931137273794
  • PolsonJLeeWMAmerican Association for the Study of Liver DiseaseAASLD position paper: the management of acute liver failureHepatology20054151179119715841455
  • FoxtonMRKendrickSSizerEChange in model for end-stage liver disease score on the transplant waiting list predicts survival in patients undergoing liver transplantationTranspl Int200612191298899417081228
  • LapetodaJLandeenLKMichalopoulosGKBedardPWAnti-apoptotic effects of cellular therapy: VTL C3A cell-secreted factors reduce in vitro hepatocellular injury via multiple mechanisms17th International Symposium on Albumin Dialysis (ISAD)September 16–18, 2016Rostock-Warnemünde, Germany
  • MaghzalGJLeckMCCollinsonELiCStockerRLimited role for the bilirubin-biliverdin redox amplification cycle in the cellular antioxidant protection by biliverdin reductaseJ Biol Chem200928443292512925919690164
  • López-VelázquezJAChávez-TapiaNCPonciano-RodríguezGBilirubin alone as a biomarker for short-term mortality in acute-on-chronic liver failure: an important prognostic indicatorAnn Hepatol201413198104
  • MathurinPAbdelnourMRamondMJEarly change in bilirubin levels is an important prognostic factor in severe alcoholic hepatitis treated with prednisoloneHepatology20033861363136914647046
  • MorrisJMForrestEHBilirubin response to corticosteroids in severe alcoholic hepatitisEur J Gastroenterol Hepatol200517775976215947554
  • LeeMKimWChoiYSpontaneous evolution in bilirubin levels predicts liver-related mortality in patients with alcoholic hepatitisPLoS One201497e10087025013906
  • LiJWuJLiuHXEarly bilirubin response in acute-on-chronic hepatitis B liver failure patients treated with corticosteroids predicates a lower 3-month mortalityInt J Clin Exp Med2016961036410373
  • FattovichGPantalenaMZagniIRealdiGSchalmSWChristensenEEuropean Concerted Action on Viral Hepatitis (EUROHEP. Effect of hepatitis B and C virus infections on the natural history of compensated cirrhosis: a cohort study of 297 patientsAm J Gastroenterol200297112886289512425564
  • FattovichGStroffoliniTZagniIDonatoFHepatocellular carcinoma in cirrhosis: incidence and risk factorsGastroenterology20041275 Suppl 1S35S5015508101