Efficacy and tolerability of a single-pill combination of telmisartan 80 mg and hydrochlorothiazide 25 mg according to age, gender, race, hypertension severity, and previous antihypertensive use: planned analyses of a randomized trial

Dingliang Zhu1 Shanghai Ruijin Hospital, Shanghai, People’s Republic of ChinaCorrespondence[email protected]

Harold Bays2 Louisville Metabolic and Atherosclerosis Research Center Inc, Louisville, KY, USA

Pingjin Gao1 Shanghai Ruijin Hospital, Shanghai, People’s Republic of China

Michaela Mattheus3 Boehringer Ingelheim International GmbH, Ingelheim, Germany

Birgit Voelker3 Boehringer Ingelheim International GmbH, Ingelheim, Germany

Luis M Ruilope4 Hospital 12 de Octubre, Madrid, Spain

Pages 1-14 | Published online: 03 Apr 2013

Cite this article

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

References

GradmanAHBasileJNCarterBLBakrisGLCombination therapy in hypertensionJ Clin Hypertens (Greenwich)201113314615421366845
PubMed Web of Science ®Google Scholar
SeverPSMesserliFHHypertension management 2011: optimal combination therapyEur Heart J201132202499250621697169
PubMed Web of Science ®Google Scholar
FranklinSSNeutelJMInitial combination therapy for rapid and effective control of moderate and severe hypertensionJ Hum Hypertens200923141118615100
PubMed Web of Science ®Google Scholar
ChobanianAVBakrisGLBlackHRSeventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressureHypertension20034261206125214656957
PubMed Web of Science ®Google Scholar
ManciaGDeBGDominiczakA2007 Guidelines for the Management of Arterial Hypertension: The Task Force for the Management of Arterial Hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)J Hypertens20072561105118717563527
PubMed Web of Science ®Google Scholar
CorraoGNicotraFParodiACardiovascular protection by initial and subsequent combination of antihypertensive drugs in daily life practiceHypertension201158456657221825231
PubMed Web of Science ®Google Scholar
BangaloreSLeyLImproving treatment adherence to antihypertensive therapy: the role of single-pill combinationsExpert Opin Pharmacother201213334535522220825
PubMed Web of Science ®Google Scholar
PloskerGLWhiteWBTelmisartan/hydrochlorothiazide: a review of its use as fixed-dose combinations in essential hypertensionDrugs200868131877189918729541
PubMed Web of Science ®Google Scholar
ZhuDLBaysHGaoPMattheusMVoelkerBRuilopeLMEfficacy and tolerability of initial therapy with single-pill combination telmisartan/hydrochlorothiazide 80/25 mg in patients with grade 2 or 3 hypertension: a multinational, randomized, double-blind, active-controlled trialClin Ther20123471613162422717420
PubMed Web of Science ®Google Scholar
ChapmanABSchwartzGLBoerwinkleETurnerSTPredictors of antihypertensive response to a standard dose of hydrochlorothiazide for essential hypertensionKidney Int20026131047105511849460
PubMed Web of Science ®Google Scholar
NeutelJMLong-term blood pressure control: what can we do?Postgrad Med20111231889321293088
PubMed Web of Science ®Google Scholar
JohnsonJAEthnic differences in cardiovascular drug response: potential contribution of pharmacogeneticsCirculation2008118131383139318809808
PubMed Web of Science ®Google Scholar
GuptaAKRacial differences in response to antihypertensive therapy: does one size fits all?Int J Prev Med20101421721921566775
PubMedGoogle Scholar
OfiliEOFerdinandKCSaundersEIrbesartan/HCTZ fixed combinations in patients of different racial/ethnic groups with uncontrolled systolic blood pressure on monotherapyJ Natl Med Assoc200698461862616623075
PubMed Web of Science ®Google Scholar
CushmanWCNeutelJMSaundersEEfficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in older vs younger patients with hypertension uncontrolled with monotherapyAm J Geriatr Cardiol2008171273618174757
PubMedGoogle Scholar
OfiliEOCableGNeutelJMSaundersEEfficacy and safety of fixed combinations of irbesartan/hydrochlorothiazide in hypertensive women: the inclusive trialJ Womens Health (Larchmt)200817693193818681815
PubMed Web of Science ®Google Scholar
NashDTCrikelairNZappeDAchieving BP goals with valsartan and HCTZ alone and in combination: pooled analysis of two randomized, double-blind, placebo-controlled studiesCurr Med Res Opin20082492617262618687165
PubMed Web of Science ®Google Scholar
WhiteWBDavidaiGSchumacherHImpact of angiotensin receptor blockade in combination with hydrochlorothiazide 25 mg in 2121 patients with stage 1–2 hypertensionJ Hum Hypertens2009231281782519357698
PubMed Web of Science ®Google Scholar
WeirMRRolfeMPotassium homeostasis and renin-angiotensin-aldosterone system inhibitorsClin J Am Soc Nephrol20105353154820150448
PubMed Web of Science ®Google Scholar
KohKKQuonMJHanSHDistinct vascular and metabolic effects of different classes of anti-hypertensive drugsInt J Cardiol20101401738119059660
PubMed Web of Science ®Google Scholar
SrivastavaTNYoungDBImpairment of cardiac function by moderate potassium depletionJ Card Fail1995131952009420651
PubMedGoogle Scholar
FranseLVPahorMDiBMSomesGWCushmanWCApplegateWBHypokalemia associated with diuretic use and cardiovascular events in the Systolic Hypertension in the Elderly ProgramHypertension20003551025103010818057
PubMed Web of Science ®Google Scholar
HwangKSKimGHThiazide-induced hyponatremiaElectrolyte Blood Press201081515721468197
PubMedGoogle Scholar
SavagePJPresselSLCurbJDInfluence of long-term, low-dose, diuretic-based, antihypertensive therapy on glucose, lipid, uric acid, and potassium levels in older men and women with isolated systolic hypertension: The Systolic Hypertension in the Elderly Program. SHEP Cooperative Research GroupArch Intern Med199815877417519554680
PubMedGoogle Scholar
BrandFNMcGeeDLKannelWBStokesJIIICastelliWPHyperuricemia as a risk factor of coronary heart disease: the Framingham StudyAm J Epidemiol1985121111183964986
PubMed Web of Science ®Google Scholar
SowersJRRaijLJialalIAngiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensivesJ Hypertens20102881761176920498618
PubMed Web of Science ®Google Scholar
KalraSKalraBAgrawalNCombination therapy in hypertension: An updateDiabetol Metabol Syndr2010214454
Web of Science ®Google Scholar

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Efficacy and tolerability of a single-pill combination of telmisartan 80 mg and hydrochlorothiazide 25 mg according to age, gender, race, hypertension severity, and previous antihypertensive use: planned analyses of a randomized trial

References

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Efficacy and tolerability of a single-pill combination of telmisartan 80 mg and hydrochlorothiazide 25 mg according to age, gender, race, hypertension severity, and previous antihypertensive use: planned analyses of a randomized trial

References

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date