References
- GhanemFAMovahedAInflammation in high blood pressure: A clinical perspectiveJ Am Soc Hypertens2007111311920409841
- Rubio-GuerraAFVargas-RoblesHVargas-AyalaGRodríguez-LopezLEscalante-AcostaBAThe effect of trandolapril and its fixed-dose combination with verapamil on circulating adhesion molecules levels in hypertensive patients with type 2 diabetesClin Exp Hypertens20083068268818855271
- RubioAFVargasHMacedaALozanoJJEscalanteBACorrelation between the levels of circulating adhesion molecules and atherosclerosis in type-2 diabetic normotensive patientsCell Adh Migr2009336937219717975
- MadamanchiNRVendrovARungeMSOxidative stress and vascular diseaseArterioscler Thromb Vasc Biol200525293815539615
- GriendlingKKSorescuDUshio-FukaiMNAD(P)H oxidase: Role in cardiovascular biology and diseaseCirc Res20008649450110720409
- KimJMontagnamiMKonKQuonMJReciprocal relations between insulin resistance and endothelial dysfunctionCirculation20061131888190416618833
- KwonNSNathanCFStuerhrDJReduced biopterin as a cofactor in the generation of nitrogen oxides by murine macrophagesJ Biol Chem198926420496205012584226
- AlpNJChannonKMRegulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular diseaseArterioscler Thromb Vasc Biol20052441342014656731
- GrossSJonesSHattoriCLRamanCSTetrahydrobiopterin: An essential cofactor of nitric oxide synthase with an elusive roleIgnarroLJNitric Oxide Biology and PathobiologyNew York, NYAcademic Press2000
- HurshmanARKrebsCEdmondsonDHuynhBHMarlettaMAFormation of a pterin radical in the reaction of the heme domain of inducible nitric oxide synthase with oxygenBiochemistry199938156891569610625434
- BauersachsJWidderJDTetrahydrobiopterin, endothelial nitric oxide synthase, and mitochondrial function in the heartHypertension20095390790819398653
- SchmidtTSAlpNJMechanisms for the role of tetrahydrobiopterin in endothelial function and vascular diseaseClin Sci2007113476317555404
- GesierichANiroomandFTiefenbavherCPRole of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolismBasic Res Cardiol200298697512607127
- WuGKellyKAHatakeyamaKMeiningerCJRegulation of endothelial tetrahydrobiopterin synthesis by l-arginineBlauNThonyBPterins, Folates and Neurotransmitters in Molecular MedicineHeilbronnSPS Verlagsgesellschaft mbH2004
- IshiiMShimizuSNagaiTShiotaKKiruchiYYamamotoTStimulation of tetrahydrobiopterin synthesis by insulin: Possible involvement of phosphatidylinositol 3-kinaseInt J Biochem Cell Biol200133657311167133
- ShiotaKIshiiMYamamotoTShimizuSKiuchiYStimulation of tetrahydrobiopterin synthesis by 17β-estradiol in brain microvascular endothelial cellsPteridines200011129132
- Rosenkrantz-WeissPSessaWCMilsteinSKaufmanSWatsonCAPoberJSRegulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cellsJ Clin Invest199493223622437514193
- IshiiMShimizuSShiotaKYamamotoSKiuchiYYamamotoTStimulation of tetrahydrobiopterin synthesis by cyclosporin A during lipopolysaccharide treatment in vascular endothelial cellsPteridines2002138993
- JohnsDGDorranceAMTramontiniNLWebbRCGlucocorticoids inhibit tetrahydrobiopterin-dependent endothelial functionExp Biol Med20012262731
- SchoedonGScheemannMBlauNEdgellCJSChafnerAModulation of human endothelial cell tetrahydrobiopterin synthesis by activating and deactivating cytokines: New perspectives on endothelium-derived relaxing factorBiochem Biophys Res Comm1993196134313488250889
- KohliRMeiningerCJHaynesTEYanWSelfJTWuGDietary L-arginine supplementation enhances endothelial nitric oxide synthesis in streptozotocin-induced diabetic ratsJ Nutr200413460060914988454
- LaursenJBSomersMKurzSEndothelial regulation of vasomotion in ApoE-deficient mice. Implications for interactions between peroxynitrite and tetrahydrobiopterinCirculation20011031282128811238274
- BakerHMilstienSKatusikZSEffect of vitamin C on the availability of tetrahydrobiopterin in human endothelial cellsJ Cardiovasc Pharmacol20013733333811243424
- KnowlesRGMoncadaSMammalian nitric oxide synthaseBiochem J19942982492547510950
- CosentinoFLuscherTFTetrahydrobiopterin and endothelial nitric synthase activityCardiovasc Res19994327427810536654
- WhitsettJMartasekPZhaoHEndothelial cell superoxide anion radical generation is not dependent on endothelial nitric oxide synthaseserine 1179 phosphorylation and endothelial nitric oxide dimer/monomer distributionFree Rad Biol Med2006402056205816716906
- Vazquez-VivarJTetrahydrobiopterin, superoxide and vascular dysfunctionFree Rad Biol Med2009471108111919628033
- CrabtreeMJSmithCILamGGoligorskyMSGrossSSRatio of 5,6,7,8-tetrahydrobiopterin to 7,8-dihydrobiopterin in endothelial cells determines glucose-elicited changes in NO vs superoxide production by eNOSAm J Physiol Heart Circ Physiol2008294H1530H154018192221
- ZouMHShiCCohenRAOxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitriteJ Clin Invest200210981782611901190
- YangYHuangAKaleyGSunDeNOS uncoupling and endothelial dysfunction in aged vesselsAm J Physiol Heart Circ Physiol2009297H1829H183619767531
- StuehrDPouSRosenGMOxygen reduction by nitric-oxide synthasesJ Biol Chem2001276145331453611279231
- HeitzerTKrohnKAlbersSMeinertzTTetrahydrobiopterin improves endothelial vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitusDiabetologia2000431435143811126415
- LandmesserUDikalovSPriceSROxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertensionJ Clin Invest20031111201120912697739
- KatusicZSd’UscioLNathKAVascular protection by tetrahydrobiopterin: Progress and therapeutic prospectsTrends Pharmacol Sci200930485419042039
- ArtuncFEssigMArtuncNEffects of tetrahydrobiopterin on nitric oxide bioavailability and renal hemodynamics in healthy volunteersJ Nephrol20082185086019034869
- AlpNJMcAteerMAKhooJChoudhuryRPChannonKMIncreased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout miceArterioscler Thromb Vasc Biol20042444545014707037
- IhlemannNRask-MadsenCHTetrahydrobiopterin restores endothelial dysfunction induced by an oral glucose challenge in healthy subjectsAm J Physiol2003285H875H882
- PorkertMSherSReddyUTetrahydrobiopterin: A novel anti-hypertensive therapyJ Hum Hypertens20082240140718322548
- SettergrenMBöhmFMalmströmREChannonKMPernowJL-arginine and tetrahydrobiopterin protects against ischemia/reperfusion-induced endothelial dysfunction in patients with type 2 diabetes mellitus and coronary artery diseaseAtherosclerosis2009204737818849028
- WilsonAMHaradaRNairNBalasubramanianNCookeJPL-arginine supplementation in peripheral arterial disease: No benefit and possible harmCirculation200711618819517592080
- SommerFKlotzTSteineritzDBlochWEvaluation of tetrahydrobiopterin as a potential therapeutic agent to treat erectile dysfunctionAsian J Androl2006815916716491266
- HattoriYHattoriSWangXSatohHNakanishiNKasaiKOral administration of tetrahydrobiopterin slows the progression of atherosclerosis in apolipoprotein E-knockout miceArterioscler Thromb Vasc Biol20072786587017272747
- RubioAFVargasGLozanoJJNarvaezJLRodriguezLComparison between isosorbide dinitrate aerosol and nifedipine in the management of hypertensive emergenciesJ Hum Hypertens19991347347610449212
- LiHFörstermannUPrevention of atherosclerosis by interference with the vascular nitric oxide systemCurr Pharm Des2009153133314519754387
- TenenbaumAFismanEZMotroML-arginine: Rediscovery in progressCardiology1998901531599892762
- BogerRHThe pharmacodynamics of L-arginineJ Nutr2007137S1650S1655
- StroesESGvan FaassenEEYoMFolic acid reverts dysfunction of endothelial nitric oxide synthaseCirc Res2000861129113410850963
- The Heart Outcomes Prevention Evaluation (HOPE) 2 InvestigatorsHomocysteine lowering with folic acid and B vitamins in vascular diseaseN Engl J Med20063541567157716531613
- AlpNJMussaSKhooJTetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP–cyclohydrolase I overexpressionJ Clin Invest200311272573512952921
- LaufsULa FataVPlutzkyJLiaoJKUpregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitorsCirculation199897112911359537338
- HattoriYNakanishiNAkimotoKYoshidaMKasaiKHMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetra-hydrobiopterin in vascular endothelial cellsArterioscler Thromb Vasc Biol20032317618212588756
- NissenSETuzcuEMSchoenhagenPEffect of intensive compared with moderate lipid-lowering therapy on progression of coronary atherosclerosis: A randomized controlled trialJAMA20042911071108014996776
- NickeningGHarrisonDGThe AT1-type angiotensin receptor in oxidative stress and atherogenesis. Part 1Circulation200210539339611804998
- DavidBMatcharDBMcCroryDCSystematic review: Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers for treating essential hypertensionAnn Intern Med2008148162917984484
- ImanishiTIkejimaHTsujiokaHAddition of eplerenone to an angiotensin-converting enzyme inhibitor effectively improves nitric oxide bioavailabilityHypertension20085173474118227404
- ImanishiTTsujiokaHIkejimaHRenin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changesHypertension20085256357218645051