Coagulative biomarkers on admission to the ICU predict acute kidney injury and mortality in patients with septic shock caused by intra-abdominal infection

References

• Singer M, Deutschman CS, Seymour CW, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016;315(8):801–810. doi:10.1001/jama.2016.028726903338
   PubMed Web of Science ®Google Scholar
• Vincent JL, De Backer D. Circulatory shock. N Engl J Med. 2013;369(18):1726–1734. doi:10.1056/NEJMra120894324171518
   PubMed Web of Science ®Google Scholar
• Levy MM, Rhodes A, Phillips GS, et al. Surviving Sepsis Campaign: association between performance metrics and outcomes in a 7.5-year study. Crit Care Med. 2015;43(1):3–12. doi:10.1097/CCM.000000000000072325275252
   PubMed Web of Science ®Google Scholar
• Angus DC, van der Poll T. Severe sepsis and septic shock. N Engl J Med. 2013;369(9):840–851. doi:10.1056/NEJMra120862323984731
   PubMed Web of Science ®Google Scholar
• Boldingh QJ, de Vries FE, Boermeester MA. Abdominal sepsis. Curr Opin Crit Care. 2017;23(2):159–166. doi:10.1097/MCC.000000000000038828107224
   PubMed Web of Science ®Google Scholar
• Hoste EA, Bagshaw SM, Bellomo R, et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med. 2015;41(8):1411–1423. doi:10.1007/s00134-015-3934-726162677
   PubMed Web of Science ®Google Scholar
• Chawla LS, Eggers PW, Star RA, Kimmel PL. Acute kidney injury and chronic kidney disease as interconnected syndromes. N Engl J Med. 2014;371(1):58–66. doi:10.1056/NEJMra121424324988558
   PubMed Web of Science ®Google Scholar
• Gordon AC, Mason AJ, Thirunavukkarasu N, et al. Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock: the VANISH randomized clinical trial. JAMA. 2016;316(5):509–518. doi:10.1001/jama.2016.1048527483065
   PubMed Web of Science ®Google Scholar
• Vanmassenhove J, Kielstein J, Jorres A, Biesen WV. Management of patients at risk of acute kidney injury. Lancet. 2017;389(10084):2139–2151. doi:10.1016/S0140-6736(17)31329-628561005
   PubMed Web of Science ®Google Scholar
• Bellomo R, Kellum JA, Ronco C, et al. Acute kidney injury in sepsis. Intensive Care Med. 2017;43(6):816–828. doi:10.1007/s00134-017-4755-728364303
   PubMed Web of Science ®Google Scholar
• Kellum JA, Lameire N, Aspelin P, et al. Kidney disease: improving global outcomes (KDIGO) acute kidney injury work group. KDIGO clinical practice guideline for acute kidney injury. Kidney Inter Suppl. 2012;2:1–138.
   Web of Science ®Google Scholar
• Gando S. Microvascular thrombosis and multiple organ dysfunction syndrome. Crit Care Med. 2010;38(2 Suppl):S35–S42. doi:10.1097/CCM.0b013e3181c9e31d20083912
   PubMed Web of Science ®Google Scholar
• Perrin J, Charron C, Francois JH, et al. Coagulation phenotypes in septic shock as evaluated by calibrated automated thrombography. Shock. 2015;43(1):74–79. doi:10.1097/SHK.000000000000027125255379
   PubMed Web of Science ®Google Scholar
• Thiery-Antier N, Binquet C, Vinault S, Meziani F, Boisramé-Helms J, Quenot J-P. Is thrombocytopenia an early prognostic marker in septic shock? Crit Care Med. 2016;44(4):764–772. doi:10.1097/CCM.000000000000152026670473
   PubMed Web of Science ®Google Scholar
• Levi M, van der Poll T. Coagulation and sepsis. Thromb Res. 2017;149:38–44. doi:10.1016/j.thromres.2016.11.00727886531
   PubMed Web of Science ®Google Scholar
• Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med. 2010;38(2 Suppl):S26–S34. doi:10.1097/CCM.0b013e3181c98d2120083910
   PubMed Web of Science ®Google Scholar
• Fourrier F. Severe sepsis, coagulation, and fibrinolysis: dead end or one way? Crit Care Med. 2012;40(9):2704–2708. doi:10.1097/CCM.0b013e318258ff3022732284
   PubMed Web of Science ®Google Scholar
• Verma SK, Molitoris BA. Renal endothelial injury and microvascular dysfunction in acute kidney injury. Semin Nephrol. 2015;35(1):96–107. doi:10.1016/j.semnephrol.2015.01.01025795503
   PubMed Web of Science ®Google Scholar
• de Stoppelaar SF, van ‘t Veer C, van der Poll T. The role of platelets in sepsis. Thromb Haemost. 2014;112(4):666–677. doi:10.1160/TH14-02-012624966015
   PubMed Web of Science ®Google Scholar
• Mihajlovic D, Lendak D, Mitic G, et al. Prognostic value of hemostasis-related parameters for prediction of organ dysfunction and mortality in sepsis. Turk J Med Sci. 2015;45(1):93–98.25790536
   PubMed Web of Science ®Google Scholar
• Greco E, Lupia E, Bosco O, Vizio B, Montrucchio G. Platelets and multi-organ failure in sepsis. Int J Mol Sci. 2017;18(10):2200. doi:10.3390/ijms18102200
   PubMed Web of Science ®Google Scholar
• Su CM, Cheng HH, Hung CW, et al. The value of serial serum cell adhesion molecules in predicting acute kidney injury after severe sepsis in adults. Clin Chim Acta. 2016;457:86–91. doi:10.1016/j.cca.2016.04.00827083317
   PubMed Web of Science ®Google Scholar
• Liu KL, Lee KT, Chang CH, Chen YC, Lin SM, Chu PH. Elevated plasma thrombomodulin and angiopoietin-2 predict the development of acute kidney injury in patients with acute myocardial infarction. Critical Care. 2014;18(3):R100. doi:10.1186/cc1371224886544
   PubMed Web of Science ®Google Scholar
• Katayama S, Nunomiya S, Koyama K, et al. Markers of acute kidney injury in patients with sepsis: the role of soluble thrombomodulin. Critical Care. 2017;21(1):229. doi:10.1186/s13054-017-1686-128841902
   PubMed Web of Science ®Google Scholar
• Solomkin JS, Mazuski JE, Bradley JS, et al. Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America. Surg Infect. 2010;11(1):79–109. doi:10.1089/sur.2009.9930
   PubMed Web of Science ®Google Scholar
• Mazuski JE, Tessier JM, May AK, et al. The surgical infection society revised guidelines on the management of intra-abdominal infection. Surg Infect. 2017;18(1):1–76. doi:10.1089/sur.2016.261
   PubMed Web of Science ®Google Scholar
• Kellum JA, Lameire N. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Critical Care. 2013;17(1):204. doi:10.1186/cc1273423394211
   PubMed Web of Science ®Google Scholar
• Hartwig J, Italiano J Jr. The birth of the platelet. J Thromb Haemost. 2003;1(7):1580–1586.12871294
   PubMed Web of Science ®Google Scholar
• Lyons PG, Micek ST, Hampton N, Kollef MH. Sepsis-associated coagulopathy severity predicts hospital mortality. Crit Care Med. 2018;46:736–742. doi:10.1097/CCM.000000000000299729373360
   PubMed Web of Science ®Google Scholar
• Benediktsson S, Frigyesi A, Kander T. Routine coagulation tests on ICU admission are associated with mortality in sepsis: an observational study. Acta Anaesthesiol Scand. 2017;61(7):790–796. doi:10.1111/aas.1291828681428
   PubMed Web of Science ®Google Scholar
• Pernerstorfer T, Hollenstein U, Hansen JB, et al. Lepirudin blunts endotoxin-induced coagulation activation. Blood. 2000;95(5):1729–1734.10688831
   PubMed Web of Science ®Google Scholar
• Puy C, Ngo ATP, Pang J, et al. Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) blocks the intrinsic pathway of coagulation, inducing the clearance and degradation of FXIa (Activated Factor XI). Arterioscler Thromb Vasc Biol. 2019;39(7):1390–1401. doi:10.1161/ATVBAHA.119.31261931242030
   PubMed Web of Science ®Google Scholar
• Aird WC. Vascular bed-specific hemostasis: role of endothelium in sepsis pathogenesis. Crit Care Med. 2001;29(7 Suppl):S28–S35. doi:10.1097/00003246-200107001-0001311445731
   PubMed Web of Science ®Google Scholar
• Zarbock A, Kellum JA, Schmidt C, et al. Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial. JAMA. 2016;315(20):2190–2199. doi:10.1001/jama.2016.582827209269
   PubMed Web of Science ®Google Scholar
• Karvellas CJ, Farhat MR, Sajjad I, et al. A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Critical Care. 2011;15(1):R72. doi:10.1186/cc1032421352532
   PubMed Web of Science ®Google Scholar
• Meziani F, Gando S, Vincent JL. Should all patients with sepsis receive anticoagulation? Yes. Intensive Care Med. 2017;43(3):452–454. doi:10.1007/s00134-016-4621-z28194512
   PubMed Web of Science ®Google Scholar
• van der Poll T, Opal SM. Should all septic patients be given systemic anticoagulation? No. Intensive Care Med. 2017;43(3):455–457. doi:10.1007/s00134-016-4607-x28194511
   PubMed Web of Science ®Google Scholar
• Zarychanski R, Abou-Setta AM, Kanji S, et al. The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis. Crit Care Med. 2015;43(3):511–518. doi:10.1097/CCM.000000000000076325493972
   PubMed Web of Science ®Google Scholar
• Wang C, Chi C, Guo L, et al. Heparin therapy reduces 28-day mortality in adult severe sepsis patients: a systematic review and meta-analysis. Critical Care. 2014;18(5):563. doi:10.1186/cc1371225318353
   PubMed Web of Science ®Google Scholar
• Warren BL, Eid A, Singer P, et al. Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: a randomized controlled trial. JAMA. 2001;286(15):1869–1878. doi:10.1001/jama.286.15.186911597289
   PubMed Web of Science ®Google Scholar
• Wikkelso A, Wetterslev J, Moller AM, Afshari A. Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding. Cochrane Database Syst Rev. 2016;8(8):CD007871.
   Google Scholar