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Original Research

Resistance To First-Line Antituberculosis Drugs And Prevalence Of pncA Mutations In Clinical Isolates Of Mycobacterium tuberculosis From Zunyi, Guizhou Province Of China

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Pages 3093-3102 | Published online: 30 Sep 2019

References

  • World Health Organization. Global tuberculosis report. 2018 Available from: http://www.who.int/tb/publications/global_report/en;2018. Accessed 78, 2019.
  • Stehr M, Elamin AA, Singh M. Pyrazinamide: the importance of uncovering the mechanisms of action in mycobacteria. Expert Rev Anti Infect Ther. 2015;13:593–603. doi:10.1586/14787210.2015.102178425746054
  • Ramirez-Busby SM, Valafar F. Systematic review of mutations in pyrazinamidase associated with pyrazinamide resistance in Mycobacterium tuberculosis clinical isolates. Antimicrob Agents Chemother. 2015;59:5267–5277. doi:10.1128/AAC.00204-1526077261
  • Streicher EM, Maharaj K, York T, et al. Rapid sequencing of the Mycobacterium tuberculosis pncA gene for detection of pyrazinamide susceptibility. J Clin Microbiol. 2014;52:4056–4057. doi:10.1128/JCM.02438-1425165081
  • World Health Organization. Technical manual for drug susceptibility testing of medicines used in the treatment of tuberculosis. 2018 Available from: http://apps.who.int/medicinedocs/documents/s23565en/s23565en.pdf. Accessed 78, 2019.
  • Yadon AN, Maharaj K, Adamson JH, et al. A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide. Nat Commun. 2017;8:588. doi:10.1038/s41467-017-00721-228928454
  • Zignol M, Dean AS, Alikhanova N, et al. Population-based resistance of Mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project. Lancet Infect Dis. 2016;16:1185–1192. doi:10.1016/S1473-3099(16)30190-627397590
  • Khan MT, Malik SI, Ali S, et al. Pyrazinamide resistance and mutations in pncA among isolates of Mycobacterium tuberculosis from Khyber Pakhtunkhwa, Pakistan. BMC Infect Dis. 2019;19:116. doi:10.1186/s12879-019-3764-230728001
  • Daneau G, Gumusboga M, De Rijk P, et al. The majority of patients with multidrug-resistant tuberculosis in Sub-Saharan Africa present a concomitant resistance to pyrazinamide. Int J Mycobacteriol. 2016;(Suppl 1):S46–S47. doi:10.1016/j.ijmyco.2016.10.01528043604
  • Ngabonziza JCS, Diallo AB, Tagliani E, et al. Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide. PLoS One. 2017;12:e0187211. doi:10.1371/journal.pone.018721129088294
  • Sengstake S, Bergval IL, Schuitema AR, et al. Pyrazinamide resistance-conferring mutations in pncA and the transmission of multidrug resistant TB in Georgia. BMC Infect Dis. 2017;17:491. doi:10.1186/s12879-017-2594-328697808
  • Li D, Song Y, Zhang CL, Li X, Xia X, Zhang AM. Screening mutations in drug-resistant Mycobacterium tuberculosis strains in Yunnan, China. J Infect Public Health. 2017;10:630–636. doi:10.1016/j.jiph.2017.04.00828623123
  • World Health Organization. Laboratory Services in Tuberculosis Control. Part III: Culture. Geneva: World Health Organization; 1998 Available from: http://apps.who.int/iris/bitstream/handle/10665/65942/WHO_TB_98.258_(part3).pdf;jsessionid=64EF54513AD4144A520B24B4E3DFCBA5?sequence=3. Accessed 78, 2019.
  • Miotto P, Cabibbe AM, Feuerriegel S, et al. Mycobacterium tuberculosis pyrazinamide resistance determinants: a multicenter study. MBio. 2014;5:e01819–14. doi:10.1128/mBio.01819-1425336456
  • Lan Y, Li Y, Chen L, Zhang J, Zhang H. Drug resistance profiles and trends in drug-resistant tuberculosis at a major hospital in Guizhou Province of China. Infect Drug Resist. 2019;12:211–219. doi:10.2147/IDR.S18853830666136
  • Zignol M, Dara M, Dean AS, et al. Drug-resistant tuberculosis in the WHO European Region: an analysis of surveillance data. Drug Resist Updat. 2013;16:108–115. doi:10.1016/j.drup.2014.02.00324631052
  • Pang Y, Zhu D, Zheng H, et al. Prevalence and molecular characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates from Southern China. BMC Infect Dis. 2017;17:711. doi:10.1186/s12879-017-2761-629110640
  • Xia Q, Zhao LL, Li F, et al. Phenotypic and genotypic characterization of pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis isolates in Zhejiang, China. Antimicrob Agents Chemother. 2015;59:1690–1695. doi:10.1128/AAC.04541-1425583712
  • Bhuju S, Fonseca Lde S, Marsico AG, et al. Mycobacterium tuberculosis isolates from Rio de Janeiro reveal unusually low correlationbetween pyrazinamide resistance and mutations in the pncA gene. Infect Genet Evol. 2013;19:1–6. doi:10.1016/j.meegid.2013.06.00823770140
  • Alexander DC, Ma JH, Guthrie JL, Blair J, Chedore P, Jamieson FB. Gene sequencing for routine verification of pyrazinamide resistance in Mycobacterium tuberculosis: a role for pncA but not rpsA. J Clin Microbiol. 2012;50:3726–3728. doi:10.1128/JCM.00620-1222895038
  • Cuevas-Córdoba B, Xochihua-González SO, Cuellar A, Fuentes-Dominguez J, Zenteno-Cuevas R. Characterization of pncA gene mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from Mexico. Infect Genet Evol. 2013;19:330–334. doi:10.1016/j.meegid.2012.12.01323321280
  • Sheen P, Requena D, Gushiken E, et al. A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance. BMC Genomics. 2017;18:769. doi:10.1186/s12864-017-4146-z29020922
  • Kahbazi M, Sarmadian H, Ahmadi A, et al. Novel mutations in pncA gene of pyrazinamide resistant clinical isolates of Mycobacterium tuberculosis. Sci Pharm. 2018;86:pii:15. doi:10.3390/scipharm86020015
  • Andres S, Gröschel MI, Hillemann D, Merker M, Niemann S, Kranzer K. A diagnostic algorithm to investigate pyrazinamide and ethambutol resistance in rifampin-resistant Mycobacterium tuberculosis isolates in a low-incidence setting. Antimicrob Agents Chemother. 2019;63:e01798–18. doi:10.1128/AAC.01798-1830455227
  • Akhmetova A, Kozhamkulov U, Bismilda V, et al. Mutations in the pncA and rpsA genes among 77 Mycobacterium tuberculosis isolates in Kazakhstan. Int J Tuberc Lung Dis. 2015;19:179–184. doi:10.5588/ijtld.14.030525574916
  • Marttila HJ, Marjamäki M, Vyshnevskaya E, et al. pncA mutations in pyrazinamide-resistant Mycobacterium tuberculosis isolates from northwestern Russia. Antimicrob Agents Chemother. 1999;43:1764–1766.10390239
  • Juréen P, Werngren J, Toro JC, Hoffner S. Pyrazinamide resistance and pncA gene mutations in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2008;52:1852–1854. doi:10.1128/AAC.00110-0818316515
  • Yüksel P, Tansel O. Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Turkey. New Microbiol. 2009;32:153–158.19579692
  • Daum LT, Konstantynovska OS, Solodiankin OS, et al. Characterization of novel Mycobacterium tuberculosis pncA gene mutations in clinical isolates from the Ukraine. Diagn Microbiol Infect Dis. 2019;93:334–338. doi:10.1016/j.diagmicrobio.2018.10.01830583880
  • Muthaiah M, Jagadeesan S, Ayalusamy N, et al. Molecular epidemiological study of pyrazinamide-resistance in clinical isolates of Mycobacterium tuberculosis from South India. Int J Mol Sci. 2010;11:2670–2680. doi:10.3390/ijms1107267020717529
  • Chaidir L, Ruesen C, Dutilh BE, et al. Use of whole-genome sequencing to predict Mycobacterium tuberculosis drug resistance in Indonesia. J Glob Antimicrob Resist. 2019;16:170–177. doi:10.1016/j.jgar.2018.08.01830172045
  • Aung WW, Ei PW, Nyunt WW, et al. Pyrazinamide resistance among multidrug-resistant Mycobacterium tuberculosis clinical isolates in Myanmar. Antimicrob Agents Chemother. 2018;62:e01984–17. doi:10.1128/AAC.01984-1729263056
  • Jonmalung J, Prammananan T, Leechawengwongs M, Chaiprasert A. Surveillance of pyrazinamide susceptibility among multidrug-resistant Mycobacterium tuberculosis isolates from Siriraj Hospital, Thailand. BMC Microbiol. 2010;10:223. doi:10.1186/1471-2180-10-22320727143
  • Gu Y, Yu X, Jiang G, et al. Pyrazinamide resistance among multidrug-resistant tuberculosis clinical isolates in a nationalreferral center of China and its correlations with pncA, rpsA, and panD gene mutations. Diagn Microbiol Infect Dis. 2016;84:207–211. doi:10.1016/j.diagmicrobio.2015.10.01726775806
  • Li D, Hu Y, Werngren J, et al. Multicenter study of the emergence and genetic characteristics of pyrazinamide-resistant tuberculosis in China. Antimicrob Agents Chemother. 2016;60:5159–5166. doi:10.1128/AAC.02687-1527297481
  • Cui Z, Wang J, Lu J, Huang X, Zheng R, Hu Z. Evaluation of methods for testing the susceptibility of clinical Mycobacterium tuberculosis isolates to pyrazinamide. J Clin Microbiol. 2013;51:1374–1380. doi:10.1128/JCM.03197-1223390285
  • Ando H, Mitarai S, Kondo Y, et al. Pyrazinamide resistance in multidrug-resistant Mycobacterium tuberculosis isolates in Japan. Clin Microbiol Infect. 2010;16:1164–1168. doi:10.1111/j.1469-0691.2009.03078.x19832709
  • Jnawali HN, Hwang SC, Park YK, et al. Characterization of mutations in multi- and extensive drug resistance among strains of Mycobacterium tuberculosis clinical isolates in Republic of Korea. Diagn Microbiol Infect Dis. 2013;76:187–196. doi:10.1016/j.diagmicrobio.2013.02.03523561273
  • Huy NQ, Lucie C, Hoa TTT, et al. Molecular analysis of pyrazinamide resistance in Mycobacterium tuberculosis in Vietnam highlights the high rate of pyrazinamide resistance-associated mutations in clinical isolates. Emerg Microbes Infect. 2017;6:e86. doi:10.1038/emi.2017.7329018250
  • CRyPTIC Consortium and the 100,000 Genomes Project, et al. Prediction of susceptibility to first-line tuberculosis drugs by DNA sequencing. N Engl J Med. 2018;379:1403–1415. doi:10.1056/NEJMoa180047430280646