Molecular Mechanisms and Epidemiology of Carbapenem-Resistant Escherichia coli Isolated from Chinese Patients During 2002–2017

References

• Gajdacs M, Abrok M, Lazar A, et al. Comparative epidemiology and resistance trends of common urinary pathogens in a tertiary-care hospital: a 10-year surveillance study. Medicina (Kaunas). 2019;55. doi:10.3390/medicina55070356
   Web of Science ®Google Scholar
• Kappell AD, DeNies MS, Ahuja NH, et al. Detection of multi-drug resistant Escherichia coli in the urban waterways of Milwaukee, WI. Front Microbiol. 2015;6:336. doi:10.3389/fmicb.2015.0033625972844
   PubMed Web of Science ®Google Scholar
• Gajdacs M. The concept of an ideal antibiotic: implications for drug design. Molecules. 2019;24:892. doi:10.3390/molecules24050892
   PubMed Web of Science ®Google Scholar
• Gajdacs M, Albericio F. Antibiotic resistance: from the bench to patients. Antibiotics (Basel). 2019;8. doi:10.3390/antibiotics8030129
   Web of Science ®Google Scholar
• Tamma PD, Han JH, Rock C, et al. Carbapenem therapy is associated with improved survival compared with piperacillin-tazobactam for patients with extended-spectrum beta-lactamase bacteremia. Clin Infect Dis. 2015;60:1319–1325. doi:10.1093/cid/civ00325586681
   PubMed Web of Science ®Google Scholar
• Ji X, Zheng B, Berglund B, et al. Dissemination of extended-spectrum beta-lactamase-producing Escherichia coli carrying mcr-1 among multiple environmental sources in rural China and associated risk to human health. Environ Pollut. 2019;251:619–627. doi:10.1016/j.envpol.2019.05.00231108295
   PubMed Web of Science ®Google Scholar
• De Gheldre Y, Maes N, Rost F, et al. Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance. J Clin Microbiol. 1997;35:152–160. doi:10.1128/JCM.35.1.152-160.19978968898
   PubMed Web of Science ®Google Scholar
• Ehrhardt AF, Sanders CC, Thomson KS, et al. Emergence of resistance to imipenem in Enterobacter isolates masquerading as Klebsiella pneumoniae during therapy with imipenem/cilastatin. Clin Infect Dis. 1993;17:120–122. doi:10.1093/clinids/17.1.1208353231
   PubMed Web of Science ®Google Scholar
• Cuzon G, Naas T, Guibert M, et al. In vivo selection of imipenem-resistant Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-15 and plasmid-encoded DHA-1 cephalosporinase. Int J Antimicrob Agents. 2010;35:265–268. doi:10.1016/j.ijantimicag.2009.10.02120034767
   PubMed Web of Science ®Google Scholar
• Fuste E, Lopez-Jimenez L, Segura C, et al. Carbapenem-resistance mechanisms of multidrug-resistant Pseudomonas aeruginosa. J Med Microbiol. 2013;62:1317–1325. doi:10.1099/jmm.0.058354-023722434
   PubMed Web of Science ®Google Scholar
• Muscarella LF. Risk of transmission of carbapenem-resistant Enterobacteriaceae and related “superbugs” during gastrointestinal endoscopy. World J Gastrointest Endosc. 2014;6:457–474. doi:10.4253/wjge.v6.i10.45725324917
   PubMedGoogle Scholar
• Logan LK, Weinstein RA. the epidemiology of carbapenem-resistant Enterobacteriaceae: the impact and evolution of a global menace. J Infect Dis. 2017;215:S28–S36. doi:10.1093/infdis/jiw28228375512
   PubMed Web of Science ®Google Scholar
• Nordmann P, Naas T, Poirel L. Global spread of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis. 2011;17:1791–1798. doi:10.3201/eid1710.11065522000347
   PubMed Web of Science ®Google Scholar
• Queenan AM, Bush K. Carbapenemases: the versatile beta-lactamases. Clin Microbiol Rev. 2007;20:440–458. doi:10.1128/CMR.00001-0717630334
   PubMed Web of Science ®Google Scholar
• Mach T, Neves P, Spiga E, et al. Facilitated permeation of antibiotics across membrane channels–interaction of the quinolone moxifloxacin with the OmpF channel. J Am Chem Soc. 2008;130:13301–13309. doi:10.1021/ja803188c18788798
   PubMed Web of Science ®Google Scholar
• Delcour AH. Outer membrane permeability and antibiotic resistance. Biochim Biophys Acta. 2009;1794:808–816. doi:10.1016/j.bbapap.2008.11.00519100346
   PubMed Web of Science ®Google Scholar
• Choi U, Lee CR. Distinct roles of outer membrane porins in antibiotic resistance and membrane integrity in Escherichia coli. Front Microbiol. 2019;10:953. doi:10.3389/fmicb.2019.0095331114568
   PubMed Web of Science ®Google Scholar
• Satlin MJ, Chen L, Patel G, et al. Multicenter clinical and molecular epidemiological analysis of bacteremia due to carbapenem-resistant Enterobacteriaceae (CRE) in the CRE epicenter of the United States. Antimicrob Agents Chemother. 2017;61. doi:10.1128/AAC.02349-16
   Web of Science ®Google Scholar
• Tangden T, Giske CG. Global dissemination of extensively drug-resistant carbapenemase-producing Enterobacteriaceae: clinical perspectives on detection, treatment and infection control. J Intern Med. 2015;277:501–512. doi:10.1111/joim.1234225556628
   PubMed Web of Science ®Google Scholar
• CLSI. Performance standard for antimicrobial susceptibility testing In: CLSI Supplement M100. 29th ed. Wayne, PA: Clinical and Laboratory Standards Institute; 2019;32-40.
   Google Scholar
• Spengler G, Kincses A, Gajdacs M, et al. New roads leading to old destinations: efflux pumps as targets to reverse multidrug resistance in bacteria. Molecules. 2017;22:468. doi:10.3390/molecules22030468
   Web of Science ®Google Scholar
• Zhang X, Zhang Y, Wang F, et al. Unravelling mechanisms of nitrofurantoin resistance and epidemiological characteristics among Escherichia coli clinical isolates. Int J Antimicrob Agents. 2018;52:226–232. doi:10.1016/j.ijantimicag.2018.04.02129753133
   PubMed Web of Science ®Google Scholar
• Hunter SB, Vauterin P, Lambert-Fair MA, et al. Establishment of a universal size standard strain for use with the PulseNet standardized pulsed-field gel electrophoresis protocols: converting the national databases to the new size standard. J Clin Microbiol. 2005;43:1045–1050. doi:10.1128/JCM.43.3.1045-1050.200515750058
   PubMed Web of Science ®Google Scholar
• Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol. 1995;33:2233–2239. doi:10.1128/JCM.33.9.2233-2239.19957494007
   PubMed Web of Science ®Google Scholar
• Nicolau DP, Carmeli Y, Crank CW, et al. Carbapenem stewardship: does ertapenem affect Pseudomonas susceptibility to other carbapenems? A review of the evidence. Int J Antimicrob Agents. 2012;39:11–15. doi:10.1016/j.ijantimicag.2011.08.01822047702
   PubMed Web of Science ®Google Scholar
• Gupta V, Ye G, Olesky M, et al. National prevalence estimates for resistant Enterobacteriaceae and Acinetobacter species in hospitalized patients in the United States. Int J Infect Dis. 2019;85:203–211. doi:10.1016/j.ijid.2019.06.01731229615
   PubMed Web of Science ®Google Scholar
• Khosravi AD, Taee S, Dezfuli AA, et al. Investigation of the prevalence of genes conferring resistance to carbapenems in Pseudomonas aeruginosa isolates from burn patients. Infect Drug Resist. 2019;12:1153–1159. doi:10.2147/IDR.S19775231123412
   PubMed Web of Science ®Google Scholar
• Hoang CQ, Nguyen HD, Vu HQ, et al. Emergence of New Delhi Metallo-Beta-Lactamase (NDM) and Klebsiella pneumoniae Carbapenemase (KPC) Production by Escherichia coli and Klebsiella pneumoniae in Southern Vietnam and Appropriate Methods of Detection: a Cross-Sectional Study. Biomed Res Int. 2019;2019:9757625. doi:10.1155/2019/975762531179337
   PubMed Web of Science ®Google Scholar
• Gong X, Zhang J, Su S, et al. Molecular characterization and epidemiology of carbapenem non-susceptible Enterobacteriaceae isolated from the Eastern region of Heilongjiang Province, China. BMC Infect Dis. 2018;18:417. doi:10.1186/s12879-018-3294-330134844
   PubMed Web of Science ®Google Scholar
• Yigit H, Queenan AM, Anderson GJ, et al. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob Agents Chemother. 2001;45:1151–1161. doi:10.1128/AAC.45.4.1151-1161.200111257029
   PubMed Web of Science ®Google Scholar
• Oteo J, Perez-Vazquez M, Bautista V, et al. The spread of KPC-producing Enterobacteriaceae in Spain: WGS analysis of the emerging high-risk clones of Klebsiella pneumoniae ST11/KPC-2, ST101/KPC-2 and ST512/KPC-3. J Antimicrob Chemother. 2016;71:3392–3399. doi:10.1093/jac/dkw32127530752
   PubMed Web of Science ®Google Scholar
• Sekizuka T, Yatsu K, Inamine Y, et al. Complete genome sequence of a blaKPC-2-positive Klebsiella pneumoniae strain isolated from the effluent of an urban sewage treatment plant in Japan. mSphere. 2018;3.doi. doi:10.1128/mSphere.00314-18
   Google Scholar
• Huang J, Ding H, Shi Y, et al. Further spread of a blaKPC-harboring untypeable plasmid in Enterobacteriaceae in China. Front Microbiol. 2018;9:1938. doi:10.3389/fmicb.2018.0193830186260
   PubMedGoogle Scholar
• Tseng SP, Wang SF, Ma L, et al. The plasmid-mediated fosfomycin resistance determinants and synergy of fosfomycin and meropenem in carbapenem-resistant Klebsiella pneumoniae isolates in Taiwan. J Microbiol Immunol Infect. 2017;50:653–661. doi:10.1016/j.jmii.2017.03.00328705769
   PubMedGoogle Scholar
• Liang WJ, Liu HY, Duan GC, et al. Emergence and mechanism of carbapenem-resistant Escherichia coli in Henan, China, 2014. J Infect Public Health. 2018;11:347–351. doi:10.1016/j.jiph.2017.09.02029107607
   PubMed Web of Science ®Google Scholar
• Chang YT, Siu LK, Wang JT, et al. Resistance mechanisms and molecular epidemiology of carbapenem-nonsusceptible Escherichia coli in Taiwan, 2012–2015. Infect Drug Resist. 2019;12:2113–2123. doi:10.2147/IDR.S20823131406467
   PubMed Web of Science ®Google Scholar
• Albiger B, Glasner C, Struelens MJ, et al. Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015. Euro Surveill. 2015;20. doi:10.2807/1560-7917.ES.2015.20.45.30062
   PubMedGoogle Scholar
• Yong D, Toleman MA, Giske CG, et al. Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob Agents Chemother. 2009;53:5046–5054. doi:10.1128/AAC.00774-0919770275
   PubMed Web of Science ®Google Scholar
• Dong F, Lu J, Wang Y, et al. A five-year surveillance of carbapenemase-producing Klebsiella pneumoniae in a pediatric hospital in china reveals increased predominance of NDM-1. Biomed Environ Sci. 2017;30:562–569. doi:10.3967/bes2017.07528807096
   PubMed Web of Science ®Google Scholar
• Kumarasamy KK, Toleman MA, Walsh TR, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis. 2010;10:597–602. doi:10.1016/S1473-3099(10)70143-220705517
   PubMed Web of Science ®Google Scholar
• Walsh TR. Emerging carbapenemases: a global perspective. Int J Antimicrob Agents. 2010;36(Suppl 3):S8–S14. doi:10.1016/S0924-8579(10)70004-2
   PubMed Web of Science ®Google Scholar
• Groundwater PW, Xu S, Lai F, et al. New Delhi metallo-beta-lactamase-1: structure, inhibitors and detection of producers. Future Med Chem. 2016;8:993–1012. doi:10.4155/fmc-2016-001527253479
   PubMed Web of Science ®Google Scholar
• Nordmann P, Boulanger AE, Poirel L. NDM-4 metallo-beta-lactamase with increased carbapenemase activity from Escherichia coli. Antimicrob Agents Chemother. 2012;56:2184–2186. doi:10.1128/AAC.05961-1122252797
   PubMed Web of Science ®Google Scholar
• Khan S, Ali A, Khan AU. Structural and functional insight of New Delhi Metallo beta-lactamase-1 variants. Future Med Chem. 2018;10:221–229. doi:10.4155/fmc-2017-014329202600
   PubMed Web of Science ®Google Scholar
• Hornsey M, Phee L, Wareham DW. A novel variant, NDM-5, of the New Delhi metallo-beta-lactamase in a multidrug-resistant Escherichia coli ST648 isolate recovered from a patient in the United Kingdom. Antimicrob Agents Chemother. 2011;55:5952–5954. doi:10.1128/AAC.05108-1121930874
   PubMed Web of Science ®Google Scholar
• Zhang F, Xie L, Wang X, et al. Further Spread of blaNDM-5 in Enterobacteriaceae via IncX3 Plasmids in Shanghai, China. Front Microbiol. 2016;7:424. doi:10.3389/fmicb.2016.0042427065982
   PubMed Web of Science ®Google Scholar
• Yang P, Xie Y, Feng P, et al. blaNDM-5 carried by an IncX3 plasmid in Escherichia coli sequence type 167. Antimicrob Agents Chemother. 2014;58:7548–7552. doi:10.1128/AAC.03911-1425246393
   PubMed Web of Science ®Google Scholar
• Krishnaraju M, Kamatchi C, Jha AK, et al. Complete sequencing of an IncX3 plasmid carrying blaNDM-5 allele reveals an early stage in the dissemination of the blaNDM gene. Indian J Med Microbiol. 2015;33:30–38. doi:10.4103/0255-0857.14837325559999
   PubMed Web of Science ®Google Scholar
• Hammerum AM, Hansen F, Olesen B, et al. Investigation of a possible outbreak of NDM-5-producing ST16 Klebsiella pneumoniae among patients in Denmark with no history of recent travel using whole-genome sequencing. J Glob Antimicrob Resist. 2015;3:219–221. doi:10.1016/j.jgar.2015.05.00327873714
   PubMed Web of Science ®Google Scholar
• Wailan AM, Paterson DL, Caffery M, et al. Draft Genome Sequence of NDM-5-Producing Escherichia coli Sequence Type 648 and Genetic Context of blaNDM-5 in Australia. Genome Announc. 2015;3. doi:10.1128/genomeA.00194-15
   Google Scholar
• Cyoia PS, Koga VL, Nishio EK, et al. Distribution of ExPEC virulence factors, bla CTX-M, fosA3, and mcr-1 in Escherichia coli isolated from commercialized chicken carcasses. Front Microbiol. 2018;9:3254. doi:10.3389/fmicb.2018.0325430692971
   PubMed Web of Science ®Google Scholar
• Bush K. Past and Present Perspectives on beta-Lactamases. Antimicrob Agents Chemother. 2018;62. doi:10.1128/AAC.01076-18
   PubMed Web of Science ®Google Scholar
• Sato N, Kawamura K, Nakane K, et al. First detection of fosfomycin resistance gene fosA3 in CTX-M-producing Escherichia coli isolates from healthy individuals in Japan. Microb Drug Resist. 2013;19:477–482. doi:10.1089/mdr.2013.006123909549
   PubMed Web of Science ®Google Scholar
• Xie M, Lin D, Chen K, et al. Molecular characterization of Escherichia coli strains isolated from retail meat that harbor blaCTX-M and fosA3 genes. Antimicrob Agents Chemother. 2016;60:2450–2455. doi:10.1128/AAC.03101-1526856843
   PubMedGoogle Scholar
• Rosa JF, Rizek C, Marchi AP, et al. Clonality, outer-membrane proteins profile and efflux pump in KPC- producing Enterobacter sp. in Brazil. BMC Microbiol. 2017;17:69. doi:10.1186/s12866-017-0970-128302074
   PubMed Web of Science ®Google Scholar
• Shi W, Li K, Ji Y, et al. Carbapenem and cefoxitin resistance of Klebsiella pneumoniae strains associated with porin OmpK36 loss and DHA-1 beta-lactamase production. Braz J Microbiol. 2013;44:435–442. doi:10.1590/S1517-8382201300020001524294234
   PubMed Web of Science ®Google Scholar
• Osei Sekyere J, Amoako DG. Carbonyl Cyanide m-Chlorophenylhydrazine (CCCP) reverses resistance to colistin, but not to carbapenems and tigecycline in multidrug-resistant Enterobacteriaceae. Front Microbiol. 2017;8:228. doi:10.3389/fmicb.2017.0022828261184
   PubMed Web of Science ®Google Scholar
• Gajdacs M, Urban E. Resistance trends and epidemiology of citrobacter-enterobacter-serratia in urinary tract infections of inpatients and outpatients (RECESUTI): a 10-year survey. Medicina (Kaunas). 2019;55. doi:10.3390/medicina55060285
   Web of Science ®Google Scholar