134
Views
6
CrossRef citations to date
0
Altmetric
Original Research

Molecular Characteristics, Antimicrobial Resistance and Virulence Gene Profiles of Staphylococcus aureus Isolates from Wuhan, Central China

, , , ORCID Icon, , , , & show all
Pages 2063-2072 | Published online: 30 Jun 2020

References

  • Tong SYC, Davis JS, Emily E, Holland TL, Fowler VG. Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management. Clin Microbiol Rev. 2015;28(3):603–661. doi:10.1128/CMR.00134-1426016486
  • Gajdacs M, Urban E. Epidemiology and resistance trends of Staphylococcus aureus isolated from vaginal samples: a 10-year retrospective study in Hungary. Acta Dermatovenerologica Alpina Pannonica Et Adriatica. 2019;28(4):143–147. doi:10.15570/actaapa.2019.35
  • Rao Q, Shang W, Hu X, Rao X. Staphylococcus aureus ST121: a globally disseminated hypervirulent clone. J Med Microbiol. 2015;64(12):1462. doi:10.1099/jmm.0.00018526445995
  • Chen H, Liu Y, Jiang X, Chen M, Wang H. Rapid change of methicillin-resistant staphylococcus aureus clones in a Chinese Tertiary Care Hospital over a 15-year period. Antimicrob Agents Chemother. 2010;54(5):1842–1847.20176895
  • Bouiller K, Gbaguidi-Haore H, Hocquet D, Cholley P, Bertrand X, Chirouze C. Clonal complex 398 methicillin-susceptible Staphylococcus aureus bloodstream infections are associated with high mortality. Clin Microbiol Infect. 2016;22(5):451–455. doi:10.1016/j.cmi.2016.01.01826851655
  • Wang Z, Zhou H, Wang H, et al. Comparative genomics of methicillin-resistant Staphylococcus aureus ST239: distinct geographical variants in Beijing and Hong Kong. BMC Genomics. 2014;15(1):1–10. doi:10.1186/1471-2164-15-52924382143
  • O’Hara FP, Amrinemadsen H, Mera RM, et al. Molecular characterization of Staphylococcus aureus in the United States 2004–2008 reveals the rapid expansion of USA300 among inpatients and outpatients. Microb Drug Resist. 2012;18(6):555. doi:10.1089/mdr.2012.005622775581
  • Gajdacs M. The continuing threat of methicillin-resistant Staphylococcus aureus. Antibiotics-Basel. 2019;8(2):27.
  • Fangyou YU, Tingjian LI, Huang X, et al. Virulence gene profiling and molecular characterization of hospital-acquired Staphylococcus aureus isolates associated with bloodstream infection. Diagn Microbiol Infect Dis. 2012;74(4):363–368. doi:10.1016/j.diagmicrobio.2012.08.01523021064
  • Li X, Huang T, Xu K, Li C, Li Y. Molecular characteristics and virulence gene profiles of Staphylococcus aureus isolates in Hainan, China. BMC Infect Dis. 2019;19(1):873. doi:10.1186/s12879-019-4547-531640587
  • Yudong L, Hui W, Na D, et al. Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. Antimicrob Agents Chemother. 2009;53(2):512–518. doi:10.1128/AAC.00804-0819029328
  • Tan S, Wan C, Wang H, Zhou W, Shu M. Relationship between nasal Carrier isolates and clinical isolates in children with Staphylococcus aureus infections. Microb Pathog. 2019;127:233–238. doi:10.1016/j.micpath.2018.11.03230502517
  • Chen Y, Liu Z, Duo L, et al. Characterization of Staphylococcus aureus from distinct geographic locations in China: an increasing prevalence of spa-t030 and SCCmec type III. PLoS One. 2014;9(4):e96255. doi:10.1371/journal.pone.009625524763740
  • Ghasemzadeh-Moghaddam H, Ghaznavi-Rad E, Sekawi Z, et al. Methicillin-susceptible Staphylococcus aureus from clinical and community sources are genetically diverse. Int J Med Microbiol. 2011;301(4):347–353. doi:10.1016/j.ijmm.2010.10.00421193348
  • Mehraj J, Akmatov MK, Strompl J, et al. Methicillin-sensitive and methicillin-resistant Staphylococcus aureus nasal carriage in a random sample of non-hospitalized adult population in northern Germany. PLoS One. 2014;9(9):e107937. doi:10.1371/journal.pone.010793725251407
  • Asadollahi P, Farahani NN, Mirzaii M, et al. Distribution of the most prevalent spa types among clinical isolates of methicillin-resistant and -susceptible staphylococcus aureus around the world: a review. Front Microbiol. 2018;9:163. doi:10.3389/fmicb.2018.0016329487578
  • Hongbin C, Yudong L, Xiuhong J, Minjun C, Hui W. Rapid change of methicillin-resistant Staphylococcus aureus clones in a Chinese tertiary care hospital over a 15-year period. Antimicrob Agents Chemother. 2010;54(5):1842.20176895
  • Dai Y, Liu J, Guo W, et al. Decreasing methicillin-resistant Staphylococcus aureus (MRSA) infections is attributable to the disappearance of predominant MRSA ST239 clones, Shanghai, 2008-2017. Emer Microbes Infect. 2019;8(1):471–478. doi:10.1080/22221751.2019.1595161
  • Tidwell J, Kirk L, Luttrell T, Pike CA. CA-MRSA decolonization strategies do they reduce recurrence rate? J Wound Ostomy Cont Nurs. 2016;43(6):577–582. doi:10.1097/WON.0000000000000277
  • Liu X, Liang J, Jiang Y, et al. Molecular characteristics of community-acquired methicillin-resistant Staphylococcus aureus strains isolated from outpatients with skin and soft tissue infections in Wuhan, China. Pathog Dis. 2016;74:4. doi:10.1093/femspd/ftw026
  • Liu C, Chen ZJ, Sun Z, et al. Molecular characteristics and virulence factors in methicillin-susceptible, resistant, and heterogeneous vancomycin-intermediate Staphylococcus aureus from central-southern China. J Microbiol Immunol Infect. 2015;48(5):490–496. doi:10.1016/j.jmii.2014.03.00324767415
  • Li X, Fang F, Zhao J, et al. Molecular characteristics and virulence gene profiles of Staphylococcus aureus causing bloodstream infection. Braz J Infect Dis. 2018;22.
  • Enright MC, Day NP, Davies CE, Peacock SJ, Spratt BG. Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus. J Clin Microbiol. 2000;38(3):1008–1015. doi:10.1128/JCM.38.3.1008-1015.200010698988
  • Robinson DA, Enright MC. Multilocus sequence typing and the evolution of methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 2004;10(2):92–97. doi:10.1111/j.1469-0691.2004.00768.x14759234
  • Ito T, Kuwahara-Arai K, Katayama Y, Uehara Y, Hiramatsu K. Staphylococcal Cassette Chromosome mec (SCCmec) analysis of MRSA. Methods Mol Biol. 2007;391:131–148.
  • Campbell SJ, Deshmukh HS, Nelson CL, et al. Genotypic characteristics of staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. J Clin Microbiol. 2008;46(2):678. doi:10.1128/JCM.01822-0718077636
  • Yuan W, Liu J, Zhan Y, et al. Molecular typing revealed the emergence of pvl-positive sequence type 22 methicillin-susceptible Staphylococcus aureus in Urumqi, Northwestern China. Infect Drug Resist. 2019;12:1719–1728. doi:10.2147/IDR.S20290631354320
  • Liang Y, Tu C, Tan C, et al. Antimicrobial resistance, virulence genes profiling and molecular relatedness of methicillin-resistant Staphylococcus aureus strains isolated from hospitalized patients in Guangdong Province, China. Infect Drug Resist. 2019;12:447–459. doi:10.2147/IDR.S19261130881052
  • Wang X, Li X, Liu W, Huang W, Fu Q, Li M. Molecular characteristic and virulence gene profiles of community-associated methicillin-resistant Staphylococcus aureus isolates from pediatric patients in Shanghai, China. Front Microbiol. 2016;7:1818. doi:10.3389/fmicb.2016.0181827895635
  • Manara S, Pasolli E, Dolce D, et al. Whole-genome epidemiology, characterisation, and phylogenetic reconstruction of Staphylococcus aureus strains in a paediatric hospital. Genome Med. 2018;10(1):82. doi:10.1186/s13073-018-0593-730424799
  • McGuinness WA, Malachowa N, DeLeo FR. Vancomycin resistance in Staphylococcus aureus. Yale J Biol Med. 2017;90(2):269–281.28656013
  • Wu D, Wang Q, Yang Y, et al. Epidemiology and molecular characteristics of community-associated methicillin-resistant and methicillin-susceptible Staphylococcus aureus from skin/soft tissue infections in a children’s hospital in Beijing, China. Diagn Microbiol Infect Dis. 2010;67(1):1–8. doi:10.1016/j.diagmicrobio.2009.12.00620227225
  • Yu Y, Yao Y, Weng Q, et al. Dissemination and molecular characterization of Staphylococcus aureus at a Tertiary Referral Hospital in Xiamen City, China. Biomed Res Int. 2017;2017:1367179. doi:10.1155/2017/136717928758109
  • Culos KA, Cannon JP, Grim SA. Alternative agents to vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections. Am J Ther. 2013;20(2):200–212. doi:10.1097/MJT.0b013e31821109ec21642833
  • Goudarzi M, Bahramian M, Satarzadeh Tabrizi M, et al. Genetic diversity of methicillin resistant Staphylococcus aureus strains isolated from burn patients in Iran: ST239-SCCmec III/t037 emerges as the major clone. Microb Pathog. 2017;105:1–7. doi:10.1016/j.micpath.2017.02.00428179118
  • Velasco V, Buyukcangaz E, Sherwood JS, Stepan RM, Koslofsky RJ, Logue CM. Characterization of Staphylococcus aureus from humans and a comparison with isolates of animal origin, in North Dakota, United States. PLoS One. 2015;10(10):e0140497. doi:10.1371/journal.pone.014049726484768
  • Li S, Sun S, Yang C, et al. The changing pattern of population structure of Staphylococcus aureus from Bacteremia in China from 2013 to 2016: ST239-030-MRSA replaced by ST59-t437. Front Microbiol. 2018;9:332. doi:10.3389/fmicb.2018.0033229535697
  • Li Y, Zhao R, Zhang X, et al. Prevalence of enterotoxin genes and spa genotypes of methicillin-resistant Staphylococcus aureus from a Tertiary Care Hospital in China. J Clin Diagn Res. 2015;9(5):Dc11–4.
  • Yu F, Liu Y, Lu C, et al. Dissemination of fusidic acid resistance among Staphylococcus aureus clinical isolates. BMC Microbiol. 2015;15:210. doi:10.1186/s12866-015-0552-z26463589
  • Li X, Fang F, Zhao J, et al. Molecular characteristics and virulence gene profiles of Staphylococcus aureus causing bloodstream infection. Braz J Infect Dis. 2018;22(6):487–494. doi:10.1016/j.bjid.2018.12.00130594541
  • Strandén AM, Frei R, Adler H, Flückiger U, Widmer AF. Emergence of SCCmec type IV as the most common type of methicillin-resistant Staphylococcus aureus in a university hospital. Infection. 2009;37(1):44–48. doi:10.1007/s15010-008-7430-718974930
  • Rossney AS, Shore AC, Morgan PM, Fitzgibbon MM, Brian OC, Coleman DC. The emergence and importation of diverse genotypes of methicillin-resistant Staphylococcus aureus (MRSA) harboring the Panton-Valentine leukocidin gene (pvl) reveal that pvl is a poor marker for community-acquired MRSA strains in Ireland. J Clin Microbiol. 2007;45(8):2554. doi:10.1128/JCM.00245-0717581935
  • Voyich JM, Michael O, Barun M, et al. Is Panton-Valentine leukocidin the major virulence determinant in community-associated methicillin-resistant Staphylococcus aureus disease? J Infect Dis. 2006;194(12):1761–1770. doi:10.1086/50950617109350
  • Song KH, Kim ES, Park KH, et al. Clinical and molecular characterization of panton-valentine leukocidin-positive invasive staphylococcus aureus infections in Korea. Microb Drug Resist. 2019;25(3):450–456. doi:10.1089/mdr.2018.023830379606
  • Gijon M, Bellusci M, Petraitiene B, et al. Factors associated with severity in invasive community-acquired Staphylococcus aureus infections in children: a prospective European multicentre study. Clin Microbiol Infect. 2016;22(7):643.e1–6. doi:10.1016/j.cmi.2016.04.004
  • Immergluck LC, Jain S, Ray SM, et al. Risk of skin and soft tissue infections among children found to be Staphylococcus aureus MRSA USA300 carriers. West J Emerg Med. 2017;18(2):201–212. doi:10.5811/westjem.2016.10.3048328210352